Top 10 Hotels in Syracuse, MO (from $57) 2026 - Competitive Prices

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Our top choices for Syracuse hotels

A gazebo in a snow-covered garden with benches and a building in the background.

A kitchen with wooden cabinets, a wooden island with stools, a refrigerator, and various kitchen appliances.

A hallway with wooden flooring, a staircase with a dark handrail, a door with a window, and a wall with framed pictures.

A white two-story house with a covered porch and a small garden area with a bench and a gazebo.

1. Hawthorne Inn

Versailles

Jean

$104 nightly

$113 total

Oct 17 - Oct 18

Total with taxes and fees

An indoor swimming pool with lounge chairs and a hot tub, surrounded by wooden walls and windows.

A hotel room with a bed, a sofa, a coffee table, and framed pictures on the wall.

A hotel room with a desk, computer, and a sofa. There is a dining area in the background with chairs and tables.

A hotel with an indoor pool, featuring a prominent sign and a brick facade.

2. Quality Inn & Suites Boonville - Columbia

Boonville

Tammie

$101 nightly

$115 total

Nov 16 - Nov 17

Total with taxes and fees

A spacious lobby with a high ceiling, ornate chandeliers, and classic furniture.

A spacious kitchen with wooden cabinets, a dining area with a round table and chairs, and a bar area with stools.

A building entrance with a classic architectural design, featuring a large arched entrance and two potted plants on either side.

A spacious living room with a fireplace, a dining area, and a bar area with wooden cabinets and a television.

3. Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel

Sedalia Downtown Historic District

Pamela

$123 nightly

$140 total

Nov 11 - Nov 12

Total with taxes and fees

A hotel room with a bed, a sofa, a television, and a large window with curtains.

A motel with a covered parking area, multiple rooms, and a visible sign for a nearby Super 8 motel.

A hotel room with a bed, two bedside tables, a window with curtains, a wall-mounted air conditioner, and a large picture of a boat on the wall.

A kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave.

4. Super 8 by Wyndham Boonville

Boonville

Robert

$69 nightly

$79 total

Nov 2 - Nov 3

Total with taxes and fees

A Sedalia Station building with a covered walkway, outdoor seating, and flower planters.

A hotel lobby with a bar area, seating arrangements, and a fireplace.

An indoor swimming pool with clear water, a diving board, and lounge chairs.

A spacious living area with a large TV, comfortable seating, and a sign reading "MISSOURI".

5. Comfort Inn Sedalia Station

Sedalia

LESLIE

$115 nightly

$131 total

Oct 31 - Nov 1

Total with taxes and fees

A swimming pool area with a covered bench, a chair, and a sign indicating pool rules.

A modern room with a blue wall, a gray sofa, a wooden coffee table, and a yellow chair.

A hotel room with a desk, two chairs, a printer, a phone, a framed picture, and a 'No Smoking' sign.

A coffee station with two coffee machines and a variety of coffee pods and cups.

6. Holiday Inn Express Boonville by IHG

Boonville

Thomas

$155 nightly

$174 total

Oct 25 - Oct 26

Total with taxes and fees

A spacious indoor area with a high ceiling and wooden beams, featuring multiple dining tables and a central counter with a display of colorful items.

A modern living room with a sofa, ottoman, and bench, a herringbone wood floor, and a large TV on the wall.

A modern building with a landscaped front yard, a Best Western sign, and a brick facade.

A spacious living area with a herringbone floor pattern, a fireplace, and a large window offering a view of the outdoors.

7. Best Western State Fair Inn

Sedalia

Russell

$123 nightly

$140 total

Oct 25 - Oct 26

Total with taxes and fees

A grand staircase with a red carpet leading to a balcony with ornate railings.

A spacious living room with a high ceiling, a large flat-screen TV, and a red patterned carpet.

A hotel room with a bed, bedside tables, a chair, a desk, and a mirror.

A spacious lobby with a reception desk, a chandelier, a clock, and a staircase.

8. Econo Lodge Truman Inn

Sedalia

John

$70 nightly

$80 total

Oct 26 - Oct 27

Total with taxes and fees

A hotel room with two single beds, a nightstand with a lamp, and a chair.

A small room with a television mounted on the wall, a microwave on a wooden table, and a small cabinet with drawers.

A neatly made bed with a grey quilt, two bedside tables with lamps, and a wooden nightstand with a remote control.

A compact kitchenette with a refrigerator, microwave, and coffee maker.

9. Western Hills Motel

Versailles

Shon

$76 nightly

$82 total

Oct 27 - Oct 28

Total with taxes and fees

A reception area with a stone wall, a welcome mat, a desk, a computer, and a pendant light.

A compact kitchen with wooden cabinets, a refrigerator, and a dining table with chairs.

A hotel room with a flat-screen TV mounted on the wall, a small desk with drawers, a microwave, and a trash bin.

A hotel room with two beds, each with green and white floral bedding, a framed picture on the wall, and a green accent wall.

10. Budget Inn

Sedalia

Amber

$65 nightly

$74 total

Oct 18 - Oct 19

Total with taxes and fees

A landscaped area with white pebbles, shrubs, and a fountain.

A large, rustic building surrounded by dense greenery.

A hotel room with a desk, a black office chair, a television mounted on the wall, a microwave, a coffee maker, and a lamp.

A reception desk with a black and white patterned tile design, a framed picture above it, and a colorful rug in front.

11. American Inn Sedalia

Sedalia

Joshua

$55 nightly

$63 total

Nov 4 - Nov 5

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, and a window with a view of the outside.

A room with a flat-screen TV mounted on the wall, a small wooden table with items on it, and a patterned carpet.

A small kitchenette with a microwave, refrigerator, and a flat-screen TV mounted on the wall. There are two chairs in front of a desk with a telephone and a small table with a box.

A laundry area with three front-loading washing machines and a refrigerator.

12. Motel 6 Sedalia, MO

Sedalia

"This room was clean. The bed was comfortable. The shower handle was falling apart and I couldn't adjust the temperature very well. The room was cold, so we turned on our heater which immediately started smoking and set off our smoke detector. We tried to tell the staff, but no one ever seemed to be around. We had a neighbor having a very loud conversation next door about owing someone else money early in the morning. Our experience was just okay."

Richard

$56 nightly

$64 total

Nov 4 - Nov 5

Total with taxes and fees

A reception area with a chandelier, a wall clock, and a signboard.

A motel with a neon sign indicating 'NO VACANCY' and a Coca-Cola vending machine.

A covered corridor with a row of windows and doors, a bench, and a parked car.

A row of motel rooms with a covered walkway, a parking area with cars, and a small garden area.

13. Super 7 Motel Sedalia

Sedalia

Kiley

$51 nightly

$57 total

Nov 1 - Nov 2

Total with taxes and fees

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Top Syracuse Hotel Reviews

Quality Inn & Suites Boonville - Columbia

10/10 Excellent

"Property location is excellent as it is right off the interstate. Close to downtown via car travel."

Best Western State Fair Inn

8/10 Good

"This is a good old hotel for a night or two. We enjoyed the large indoor space for relaxing and playing games. The fridge in the room was larger than most. Bathroom was divided and the tub/toilet part was very tight. Within walking distance of a good restaurant. Plenty of parking. The breakfast buffet had real scrambled eggs, a big plus."

Comfort Inn Sedalia Station

10/10 Excellent

"I didn't like the shampoo,conditioner,body wash or lotion dispensors."

Super 8 by Wyndham Boonville

8/10 Good

"Staff was very friendly and helpful. I was working nights on the highway and needed to find a place that would allow me to check in at 5:00am and after calling multiple hotels this was the only that would accommodate me. The room was clean and slightly updated. Only complaint was the bed frame was all metal and made a lot of noise when moving around on the bed. Overall I would stay here again."

Hawthorne Inn

10/10 Excellent

"The location is awesome, the rooms are nice and the amenities are great."

4 Bedroom Comfortable Cottage

10/10 Excellent

"Very family and pet friendly! The house and location was perfect for what we needed!! Nice communication.."

Holiday Inn Express Boonville by IHG

8/10 Good

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Scarlet Suite

10/10 Excellent

"N"

Econo Lodge Truman Inn

8/10 Good

"Very nice and helpful owners. I would prefer a bit of carpeting in the room but overall a good value. Thanks for hosting us!"

More cheap stays in Syracuse

American Inn Sedalia

1217 S Limit Ave Sedalia MO

$55 nightly

$63 total

Nov 4 - Nov 5

Total with taxes and fees

Motel 6 Sedalia, MO

3402 W Broadway Blvd Sedalia MO

$56 nightly

$64 total

Nov 4 - Nov 5

Total with taxes and fees

5.6/10 (763 reviews)

Days Inn by Wyndham Boonville

2401 Pioneer St Boonville MO

$61 nightly

$70 total

Nov 8 - Nov 9

Total with taxes and fees

Econo Lodge Truman Inn

3501 W Broadway Blvd Sedalia MO

$70 nightly

$80 total

Oct 26 - Oct 27

Total with taxes and fees

5.8/10 (872 reviews)

Quality Inn & Suites Boonville - Columbia

2427 Mid America Industrial Dr Boonville MO

$101 nightly

$115 total

Nov 16 - Nov 17

Total with taxes and fees

7.4/10 Good! (642 reviews)

Comfort Inn Sedalia Station

3600 W Broadway Blvd Sedalia MO

$115 nightly

$131 total

Oct 31 - Nov 1

Total with taxes and fees

9.2/10 Wonderful! (674 reviews)

Hotels in Syracuse with star-rating

Frequently asked questions

What is the best area to stay in Syracuse?

The best area to stay in Syracuse is the downtown district, particularly around Armory Square and the Connective Corridor, as it offers the most options for lodging and activities.This area is the city's main entertainment and dining hub, with many restaurants, cafes, and shops housed in historic buildings. Armory Square, a pedestrian-friendly district, is a central point for evening activities. The Connective Corridor links downtown with Syracuse University, providing easy access to cultural institutions like the Everson Museum of Art and the Carrier Dome.Couples will find downtown Syracuse appealing for its variety of dining experiences and evening entertainment options. Many hotels in this area offer amenities such as high-end fitness equipment and on-site dining, suiting a comfortable and convenient stay.For solo travelers, staying downtown provides easy access to public transportation and a concentration of points of interest within walking distance.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Syracuse.

How much is the nightly rate at a Syracuse hotel?

Prices for hotels in Syracuse often vary, but you can find a great deal from $57 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Find hotels in Syracuse, MO from $57

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Syracuse

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Syracuse hotels

1. Hawthorne Inn

2. Quality Inn & Suites Boonville - Columbia

3. Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel

4. Super 8 by Wyndham Boonville

5. Comfort Inn Sedalia Station

6. Holiday Inn Express Boonville by IHG

7. Best Western State Fair Inn

8. Econo Lodge Truman Inn

9. Western Hills Motel

10. Budget Inn

11. American Inn Sedalia

12. Motel 6 Sedalia, MO

13. Super 7 Motel Sedalia

Top Syracuse Hotel Reviews

Quality Inn & Suites Boonville - Columbia

Best Western State Fair Inn

Comfort Inn Sedalia Station

Super 8 by Wyndham Boonville

Hawthorne Inn

4 Bedroom Comfortable Cottage

Holiday Inn Express Boonville by IHG

Scarlet Suite

Econo Lodge Truman Inn

More cheap stays in Syracuse

American Inn Sedalia

Motel 6 Sedalia, MO

Days Inn by Wyndham Boonville

Econo Lodge Truman Inn

Quality Inn & Suites Boonville - Columbia

Comfort Inn Sedalia Station

Hotels in Syracuse with star-rating

Frequently asked questions

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