An aerial view of a coastal landscape with a dam, farmland, and dense forests.

Find 2 Star Hotels in Santee, SC from $61

Check availability on Santee 2 Star Hotels

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Oct 4 - Oct 5
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Oct 5 - Oct 6
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Oct 9 - Oct 11
In two weeks
Oct 16 - Oct 18

Our top choices for Santee 2-star hotels

A breakfast area with a self-service counter, refrigerated display, and a digital menu board.
A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.
A modern lobby with a blue sofa, teal chairs, and a wooden table.
A modern hotel lobby with a central reception desk, a children's play area, and a restaurant named "Top It Break."

1. Tru By Hilton Santee

Tru By Hilton Santee
Santee
United States
Connor
$101 nightly
$112 total
Oct 11 - Oct 12
Total with taxes and fees
Tru By Hilton Santee
A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.
A Baymont by Wyndham hotel with a blue and yellow facade, a covered parking area, and a large parking lot.
A hotel corridor with blue doors, a covered walkway, and a parking lot in the background.
A spacious dining area with multiple tables and chairs, large windows, and a patterned carpet.

2. Baymont by Wyndham Santee

Baymont by Wyndham Santee
Santee
United States
Cindy
$80 nightly
$89 total
Oct 5 - Oct 6
Total with taxes and fees
Baymont by Wyndham Santee
A hotel room with two beds, a desk, a chair, and a mirror.
A wooden pergola with a bench, a well-maintained lawn, and a parking area with buildings in the background.
A living room with a sofa, armchair, coffee table, and a flat-screen TV mounted on the wall.
A modern cafe with a stone backsplash, wooden cabinets, and yellow chairs.

3. SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
Manning
United States
Bruce
$95 nightly
$105 total
Oct 25 - Oct 26
Total with taxes and fees
SureStay Hotel by Best Western Manning
A self-service kiosk with a beverage cooler, microwave, and various food items.
A pool table in a room with a colorful mural, chairs, and a sofa.
A breakfast counter with a sign reading 'TOP IT BREAKFAST,' a coffee machine, a yogurt dispenser, and various food items.
A modern interior with a dining area, seating arrangements, and a reception desk.

4. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
Orangeburg
United States
Deborah
$118 nightly
$131 total
Oct 18 - Oct 19
Total with taxes and fees
Tru by Hilton Orangeburg
A two-story building with a sign reading "PachTree Inn".
A reception desk with a clock, framed certificates, and a window with a view.
A compact hotel room with a kitchenette, a television, a desk, and a chair.
A clean, well-lit dining area with round tables and chairs, a kitchen in the background, and a decorative leaf on the wall.

5. Peach Tree Inn

Peach Tree Inn
St. George
United States
Linda
$57 nightly
$62 total
Oct 11 - Oct 12
Total with taxes and fees
Peach Tree Inn
A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.
A hotel room with two beds, a seating area, and a large abstract painting on the wall.
A modern hotel room with a grey sofa, a flat-screen TV, a desk with a lamp, and abstract wall art.
An outdoor patio area with a fire pit, seating, and tables.

6. SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
Orangeburg
United States
Henrietta
$109 nightly
$121 total
Oct 12 - Oct 13
Total with taxes and fees
SpringHill Suites by Marriott Orangeburg
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.
A modern living room with a sofa, a red ottoman, a TV mounted on the wall, and a wooden entertainment unit.
A spacious lobby with a modern staircase, seating area with orange and teal chairs, and a fireplace.
A modern living room with teal and orange chairs, a grey sofa, a fireplace, and a staircase.

7. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
United States
santa
$106 nightly
$117 total
Nov 1 - Nov 2
Total with taxes and fees
Comfort Inn & Suites Santee
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.
A modern hotel with a swimming pool, outdoor seating, and a sign reading "Hampton Inn".
A Hampton Inn hotel at night with a well-lit facade and a parking lot in the foreground.
A gym with treadmills, weight machines, and a wall of dumbbells.

8. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
United States
sandra
$110 nightly
$122 total
Oct 11 - Oct 12
Total with taxes and fees
Hampton Inn Santee-I-95
A hotel room with two beds, a desk, and a chair. There are wall-mounted lamps and a large window with curtains.
A Comfort Inn & Suites hotel with a brick facade, multiple windows, and a clear blue sky.
A reception area with a wooden reception desk, a wall-mounted clock, and a welcome mat.
A swimming pool with a 4ft depth marker, lounge chairs, and a covered seating area.

9. Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg
Orangeburg
United States
LINA
$98 nightly
$108 total
Oct 11 - Oct 12
Total with taxes and fees
Comfort Inn & Suites Orangeburg
A two-story building with a grey facade, large windows, and a covered entrance area.
A hotel reception area with a counter, coffee machines, and a refrigerator.
A Red Roof Inn with two red leather armchairs and a small wooden table in front of a stone-patterned wall.
A hotel room with a bed, a nightstand, a chair, and a bathroom visible through an open door.

10. Red Roof Inn Orangeburg

Red Roof Inn Orangeburg
Orangeburg
United States
phyllis
$57 nightly
$63 total
Oct 19 - Oct 20
Total with taxes and fees
Red Roof Inn Orangeburg
A hotel lobby with a large potted plant, a blue armchair, a dining area with chairs and a table, and a red doormat with the hotel name.
A compact living space with a dining area, kitchenette, and a large window with blinds.
A two-story hotel with a covered entrance and a parking lot.
A compact kitchen with wooden cabinets, a microwave, and a dining area with purple chairs.

11. Econo Lodge St. George

Econo Lodge St. George
St. George
United States
Michelle
$67 nightly
$73 total
Oct 25 - Oct 26
Total with taxes and fees
Econo Lodge St. George
A hotel entrance with a sign reading "Best Western PLISS."
A modern kitchen with a red accent wall, white cabinetry, and a built-in espresso machine.
A spacious kitchen with white cabinets, a dining area with red patterned chairs, and a fireplace.
A spacious living room with a large window, a ceiling fan, and a vibrant red accent wall.

12. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
United States
Johnny
$131 nightly
$145 total
Oct 14 - Oct 15
Total with taxes and fees
Best Western Plus Santee Inn
A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.
A modern kitchen with a wooden table and bench, blue cabinets, and a yellow pendant light fixture.
A modern indoor swimming pool with clear glass walls, sunlit lounge areas, and a view of greenery outside.
A hotel with a modern design, featuring a prominent 'Spark' sign, a well-maintained lawn, and a clear driveway.

13. Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
Orangeburg
United States
TaNikka
$98 nightly
$108 total
Oct 8 - Oct 9
Total with taxes and fees
Spark by Hilton Orangeburg
A hotel room with a bed, a desk, a chair, a sofa, and a table.
A Baymont Inn & Suites reception desk with a sign indicating Orangeburg, South Carolina.
A gym with cardio equipment, dumbbells, and a TV on a shelf.
A breakfast corner with wooden tables and chairs, a coffee machine, and a sign indicating breakfast hours.

14. Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North
Orangeburg
United States
SHERRY
$55 nightly
$61 total
Oct 12 - Oct 13
Total with taxes and fees
Baymont by Wyndham Orangeburg North
A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.
A gym with treadmills, a bench, and a ball.
A snack shop with a sign reading "Hampton Suite Shop" and a variety of snacks and drinks on display.
A hotel room with a large bed, a desk with a flat-screen TV, a chair, a desk lamp, and a window with curtains.

15. Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
Orangeburg
United States
sonia
$130 nightly
$145 total
Oct 25 - Oct 26
Total with taxes and fees
Hampton Inn & Suites Orangeburg
A breakfast bar with pastries, fruits, and a vase with flowers.
A hotel room with two beds, a nightstand, and two wall-mounted lamps.
A Travelodge motel with a parking lot and a signboard.
A hotel bathroom with a sink, mirror, towel rack, and a door leading to the bedroom.

16. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
Orangeburg
United States
Beth
$62 nightly
$69 total
Oct 5 - Oct 6
Total with taxes and fees
Travelodge by Wyndham Orangeburg
A hotel lobby with a reception desk, seating area, and a large potted plant.
A hotel lobby with multiple seating areas, a reception desk, and a television.
A hotel lobby with seating areas, a television, and a patterned carpet.
A Hampton Inn hotel with a clear sky.

17. Hampton Inn Manning

Hampton Inn Manning
Manning
United States
Shara
$135 nightly
$150 total
Oct 18 - Oct 19
Total with taxes and fees
Hampton Inn Manning
A lobby with a reception desk, a sofa, a coffee station, and a flag.
A modern hotel lobby with a green ceiling, a grey sofa, a patterned ottoman, a wooden bench, and a chair with a geometric throw.
A hotel room with a large bed, a desk, a chair, a nightstand, and a wall-mounted lamp.
A Holiday Inn Express & Suites building with a clear entrance, a covered waiting area, and a landscaped garden.

18. Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
Orangeburg
United States
Jenelyn
$105 nightly
$117 total
Nov 1 - Nov 2
Total with taxes and fees
Holiday Inn Express & Suites Orangeburg by IHG
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.
A living room with a brown sofa set, a wooden coffee table, and a chandelier.
A hotel room with a flat-screen TV, a desk with a chair, a microwave, and a refrigerator.
A spacious kitchen with a central island, a chandelier, and a sign indicating 'Quality' on the wall.

19. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
United States
Mark
$59 nightly
$65 total
Oct 25 - Oct 26
Total with taxes and fees
Quality Inn & Suites Santee I-95
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.
A kitchen with a countertop, cabinets, a microwave, and a sink.
A room with a flat-screen TV mounted on the wall, a small round table with a computer and keyboard, a chair, and a framed picture above the table.
A bathroom with a granite countertop, a sink, a mirror, and a light fixture above the mirror.

20. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
United States
Joshua
$64 nightly
$71 total
Oct 11 - Oct 12
Total with taxes and fees
Travelodge by Wyndham Santee
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Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Santee.
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

9074 Old Number Six Hwy Santee SC
$139 nightly
$154 total
Oct 11 - Oct 12
Total with taxes and fees
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg

663 Citadel Road Orangeburg SC
$101 nightly
$112 total
Nov 1 - Nov 2
Total with taxes and fees
8.4/10 Very Good! (834 reviews)
Fairfield Inn by Marriott Orangeburg
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

139 Bradford Blvd Santee SC
$104 nightly
$115 total
Oct 18 - Oct 19
Total with taxes and fees
Holiday Inn Santee by IHG
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

See all hotels in Santee
A tree with Spanish moss and autumn leaves in a body of water.

Top Santee Hotel Reviews

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

8/10 Good
"Good cleaning room, good ac"
Benjamin 2-night trip
Posted 6 days ago
Travelodge by Wyndham Santee
Red Roof Inn Santee

Red Roof Inn Santee

10/10 Excellent
"Nice place. Clean & mattress was super comfy!"
Karyn 1-night trip
Posted 1 month ago
Red Roof Inn Santee

Find out more about Santee

When you've got to get away to a new or favorite destination without breaking the bank, Santee awaits with top 2 Star hotels and a change of scenery. Stay on your feet visiting top attractions that draw of visitors, or sip a cup of coffee nearby and relax. You're about to find out why both locals and travelers love this place.

The Perfect 2 Star Hotel at the Perfect Price

2 Star hotels are in high demand in Santee. You'll find the best deals right here, so book early and save on a great getaway. Thanks to several convenient locations and comfortable amenities, you'll find 2 Star Hotel that suits your vacation style. Stay here and be one of the first guests to leave a review and share your thoughts. So, savor the comfort of a well-kept room and attentive hospitality. With our travel deals, the world is wide open to you one hotel at a time, and the globe-trotting starts in Santee.

Reserve Your Two-Star Accommodation Today

Plan your trip to Santee now with Expedia's easy online travel booking and start relaxing before you even leave the house. Recently, this region has seen a decline in tourism. Take advantage of the 2 Star Hotel availability and easy-going atmosphere.

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