Title: The Best 2 Star Hotels in Santee, SC from $63 | Expedia.com

[Santee Travel Guide](https://expedia.com/Santee.dx9953)[Hotels in Santee](https://expedia.com/Santee-Hotels.d9953.Travel-Guide-Hotels)[Vacation Rentals in Santee](https://expedia.com/Santee-Vacation-Rentals.d9953.Travel-Guide-VacationRentals)[Flights to Santee](https://expedia.com/Cheap-Flights-To-Santee.d9953.Travel-Guide-Flights)[Car Rentals in Santee](https://expedia.com/Car-Rentals-In-Santee.d9953.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.com/Santee.d9953.Destination-Travel-Guides)

![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Santee 2 Star Hotels

Tonight

[Mar 19 - Mar 20](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-03-19&endDate=2026-03-20&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 20 - Mar 21](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-03-20&endDate=2026-03-21&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santee 2-star hotels

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/320acff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1c5cc7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Santee

[](https://www.expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information)

Santee

8.0/10

Very Good

(1,428 reviews)

"Room were very clean and staff was very helpful. I would stay there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Charolette

$80 nightly

$89 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/99021580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business center](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tru By Hilton Santee

[](https://www.expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information)

Santee

9.2/10

Wonderful

(761 reviews)

"Great place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Deborah

$118 nightly

$131 total

Apr 13 - Apr 14

Total with taxes and fees

[](https://www.expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information)

![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/27faffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e4316a7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e6b95688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/9246a04a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SureStay Hotel by Best Western Manning

[](https://www.expedia.com/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information)

Manning

8.6/10

Excellent

(1,001 reviews)

"Only stayed 2 nights. It was clean and comfortable "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Samuel

$95 nightly

$105 total

Mar 30 - Mar 31

Total with taxes and fees

[](https://www.expedia.com/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information)

![Free breakfast](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/fcd98400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Non Smoking | Iron/ironing board, free cribs/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/1ffbf2b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5472b058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Santee-I-95

[](https://www.expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information)

Santee

9.6/10

Exceptional

(1,000 reviews)

"Clean, great staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joseph

$135 nightly

$150 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Non Smoking | Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/b4a7d12b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/ca4e9299.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/7655013c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham, Orangeburg

[](https://www.expedia.com/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information)

Orangeburg

6.8/10

(929 reviews)

"Easy check in and out, good location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Theresa

$58 nightly

$64 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/99c8fb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/eb4d1288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c836e9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c5155ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tru by Hilton Orangeburg

[](https://www.expedia.com/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information)

Orangeburg

9.2/10

Wonderful

(1,001 reviews)

"Excellent stopover for us!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Georgina

$114 nightly

$127 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/67da47be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/044c704d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Santee Inn

[](https://www.expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information)

Santee

8.8/10

Excellent

(1,001 reviews)

"Clean room, polite staff , "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

samantha

$119 nightly

$132 total

Mar 26 - Mar 27

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/8229e487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e5b64ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e0b4742d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SpringHill Suites by Marriott Orangeburg

[](https://www.expedia.com/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information)

Orangeburg

8.8/10

Excellent

(717 reviews)

"Very nice & sweet staff, very clean rooms and great breakfast. Not to mention the heated pool is a plus"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shautyll

$114 nightly

$126 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information)

![Room, 2 Queen Beds, Accessible, Non Smoking (Efficiency) | Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/2dd4e6c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/2f324808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/09406598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/c5e580c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites Orangeburg

[](https://www.expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information)

Orangeburg

8.0/10

Very Good

(586 reviews)

"Great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cynthia

$105 nightly

$116 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2556x0y4-5cb4ef80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2482x3y0-b2c385e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2558x3y4-5a11a251.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2557x0y3-a96a0495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spark by Hilton Orangeburg

[](https://www.expedia.com/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information)

Orangeburg

7.8/10

Good

(1,002 reviews)

"Newly Renovated, clean carpet, comfortable bed and pillows."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vivian

$103 nightly

$115 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information)

![Breakfast area](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/5f1ffd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/c4ff1065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/d4b79aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travelodge by Wyndham Orangeburg

[](https://www.expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information)

Orangeburg

8.2/10

Very Good

(1,002 reviews)

"Conveniently located just off I26, this motel is very clean and beds are comfortable and rooms are quiet. Rooms could use some updating but can’t complain for the price. Lots of restaurants around to choose from and motel supplies coffee and cereal for breakfast in front dining area. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Yvonne

$71 nightly

$79 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information)

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/c1880a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/bc8b5a93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/efa2345e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/b034ff09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Peach Tree Inn

[](https://www.expedia.com/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information)

St. George

7.4/10

Good

(176 reviews)

"Clean carpetted floor.."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Conrad

$72 nightly

$78 total

Mar 20 - Mar 21

Total with taxes and fees

[](https://www.expedia.com/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information)

![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/0b55a618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites Santee

[](https://www.expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information)

Santee

8.0/10

Very Good

(1,000 reviews)

"Hotel was a little dated but clean."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Deborah

$110 nightly

$122 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/b15e751d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3ea4aa47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/581bc335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3e8501ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Orangeburg North

[](https://www.expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information)

Orangeburg

6.0/10

(1,001 reviews)

"The rooms were clean and staff was courteous. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Yojuana

$57 nightly

$63 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/44be5cac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/e844503c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/ca4d16db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Orangeburg

[](https://www.expedia.com/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information)

Orangeburg

9.4/10

Exceptional

(793 reviews)

"We travel regularly and this was the best breakfast of any of the places we had stayed. Facility was clean and service was friendly."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janet

$139 nightly

$154 total

Apr 19 - Apr 20

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/e77a8624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/4c792a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/1295e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn & Suites Santee I-95

[](https://www.expedia.com/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information)

Santee

6.0/10

(485 reviews)

"Easy parking, good breakfast, nice atmosphere, clean "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barbara

$65 nightly

$73 total

Mar 26 - Mar 27

Total with taxes and fees

[](https://www.expedia.com/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information)

![Suite, 1 King Bed, Accessible, Smoking | Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/81259c64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/6a21d794.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/3f3e2740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/d44bb419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn & Suites Orangeburg

[](https://www.expedia.com/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information)

Orangeburg

6.2/10

(645 reviews)

"Clean and staff very pleasant"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Larry

$63 nightly

$70 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/c19ebd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/c4341f52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/ee5c02dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed with Sofa bed | In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/37c1c14e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Orangeburg by IHG

[](https://www.expedia.com/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information)

Orangeburg

8.6/10

Excellent

(815 reviews)

"Needed a place for the night and this was just what we wanted"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Steve

$121 nightly

$134 total

Mar 25 - Mar 26

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/c2c672f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/8a3bfd5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/60f2d52c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/fb6254c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Manning

[](https://www.expedia.com/Sumter-Hotels-Hampton-Inn-Manning.h1418684.Hotel-Information)

Manning

8.4/10

Very Good

(1,002 reviews)

"Available, very clean and the staff was very nice."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

richard k

$126 nightly

$140 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Sumter-Hotels-Hampton-Inn-Manning.h1418684.Hotel-Information)

![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/5b7ee831.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business center](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travelodge by Wyndham Santee

[](https://www.expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information)

Santee

7.2/10

Good

(708 reviews)

"Good location for amenities and walking and driving distance "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gezeall

$63 nightly

$70 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information)

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## Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Santee.

![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Fairfield Inn & Suites by Marriott Santee

9074 Old Number Six Hwy Santee SC

$143 nightly

$159 total

Apr 5 - Apr 6

Total with taxes and fees

9.8/10 Exceptional! (1,001 reviews)

[](https://expedia.com/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information)

![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Fairfield Inn by Marriott Orangeburg

663 Citadel Road Orangeburg SC

$88 nightly

$98 total

Apr 13 - Apr 14

Total with taxes and fees

8.4/10 Very Good! (738 reviews)

[](https://expedia.com/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information)

![Holiday Inn Santee by IHG](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Holiday Inn Santee by IHG

139 Bradford Blvd Santee SC

$136 nightly

$151 total

Mar 22 - Mar 23

Total with taxes and fees

8.2/10 Very Good! (1,000 reviews)

[](https://expedia.com/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information)

Still don't see what you're looking for?

[See all properties in Santee.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F20%2F2026&endDate=3%2F21%2F2026&regionId=9953&star=20)

You can also use these popular filters to refine your search.

[Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F20%2F2026&endDate=3%2F21%2F2026&regionId=9953&star=20&star=20&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F20%2F2026&endDate=3%2F21%2F2026&regionId=9953&star=20&star=20&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F20%2F2026&endDate=3%2F21%2F2026&regionId=9953&star=20&star=20&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F20%2F2026&endDate=3%2F21%2F2026&regionId=9953&star=20&star=20&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F20%2F2026&endDate=3%2F21%2F2026&regionId=9953&star=20&star=20&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

[See all hotels in Santee](https://www.expedia.com/Hotel-Search?startDate=2026-04-02&endDate=2026-04-03&adults=2&regionId=9953)

![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=899&h=634&p=1&q=high)

## Top Santee Hotel Reviews

![Super 8 by Wyndham, Orangeburg](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21_y.jpg)

### Super 8 by Wyndham, Orangeburg

2/10 Terrible

"Disgusting room and faulty plumbing in a horrible area. "

[](https://expedia.com/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information)

![Travelodge by Wyndham Santee](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40_y.jpg)

### Travelodge by Wyndham Santee

8/10 Good

" Clean room "

[](https://expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information)

![Ramada by Wyndham Santee I-95](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/d34bd120_y.jpg)

### Ramada by Wyndham Santee I-95

2/10 Terrible

"After booking the room and later reading reviews, I was concerned. I met with the desk clerk prior to checking in and asked to see the room first due to the reviews. He was more than happy to allow it, although he stated this is NOT the room i would be staying in, but could expect the same level of cleanliness. My wife and I inspected the room. She saw bugs on the trim under the bathroom counter and countless amounts of roach poop on the ledge of the trim. The room smelled of mildew and the carpet was damp. When I brought this to the mas attention he said " Show Me The Bugs " . We went to the room to show his, which naturally the bugs had left. I showed him the bug poop and he became irrate. He stated " If You Needed a Cancellation, This is NOT the way to get it. This Is Not gentleman Like AT ALL " !. I explained I had not wanted a cancellation upon arrival, however I did now as the room was not up to par for my family and I to stay in. He then yelled at me " Forget It, You Are Not Getting a Cancellation, I Changed My Mind". I Left, booked a room elsewhere and proceeded to complain to Hotels.com about it. They reached out to the manager, and he stayed true what he said and denied cancellation and refund of the booking. I Advise Hotels.COM to remove this location from their list of approved locations as it has and will continue to hurt relations with customers in the future. "

[](https://expedia.com/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information)

![Super 8 by Wyndham Santee](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881_y.jpg)

### Super 8 by Wyndham Santee

10/10 Excellent

"I originally booked one night, but because the entire staff made me feel relaxed, I decided to stay an additional night. The lady at the check-in desk said they try to get good reviews from guests. I needed to do a Microsoft Teams interview, so I needed a really good internet connection. The pool is open from 9 am to 10 pm. The staff is very kind and friendly."

[](https://expedia.com/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information)

## Find out more about Santee

When you've got to get away to a new or favorite destination without breaking the bank, Santee awaits with top 2 Star hotels and a change of scenery. Stay on your feet visiting top attractions that draw of visitors, or sip a cup of coffee nearby and relax. You're about to find out why both locals and travelers love this place. 

### The Perfect 2 Star Hotel at the Perfect Price

2 Star hotels are in high demand in Santee. You'll find the best deals right here, so book early and save on a great getaway. Thanks to several convenient locations and comfortable amenities, you'll find 2 Star Hotel that suits your vacation style. Stay here and be one of the first guests to leave a review and share your thoughts. So, savor the comfort of a well-kept room and attentive hospitality. With our travel deals, the world is wide open to you one hotel at a time, and the globe-trotting starts in Santee.

### Reserve Your Two-Star Accommodation Today

Plan your trip to Santee now with Expedia's easy online travel booking and start relaxing before you even leave the house. Recently, this region has seen a decline in tourism. Take advantage of the 2 Star Hotel availability and easy-going atmosphere.

## Explore a world of travel with Expedia

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