Eastern Iowa, IA

Travel Guide

A modern glass building with a bridge in the background.
A vast green field with rows of crops, a distant red barn, and a few scattered buildings.
A river with a bridge, benches, and flower planters along the walkway.
A large brick building with a tall chimney, surrounded by greenery and a clear sky.
A park with a pond, a pepsi vending machine, and people walking along the path.

Explore the banks of the great Mississippi River and discover the life that has erupted from it. Museums, panoramas and plenty of fresh air await you.

Eastern Iowa is bordered by the snaking Mississippi River. Life has long revolved around the massive river, with the region’s nature, history and culture all entwined with it. Visit Eastern Iowa for a flavor of the Midwest, where tradition, astounding natural beauty and welcoming residents characterize the region.

Begin your explorations at the charming city of Dubuque. Learn about the vast river and its many different residents at the impressive National Mississippi River Museum and Aquarium, part of a sprawling riverfront development. The museum and aquarium depict all types of life existing along the waterway, from steamboat sailors to aquatic species.

Visit the Mines of Spain Recreation Area just south of the city, which offers a beautiful panorama of the Mississippi as well as a maze of walking trails and picnic spots. Back in the city, ride the 19th-century Fenelon Place funicular for incredible city views. North of the city, the Dubuque Arboretum and Botanical Gardens is a delightful place to relax and breathe in fresh Iowa air.

Outside Dubuque, Eastern Iowa is steeped in tradition. Tour the quaint town of Dyersville, the set for the baseball movie Field of Dreams, before heading south to Davenport. One of the main attractions here is the Figge Art Museum, which includes a collection of Midwest paintings by Iowa native Grant Wood, painter of the famous American Gothic painting.

Dubuque and Davenport both have regional airports and are a 3-hour drive from the international airport in Des Moines, the state capital. In addition, Eastern Iowa offers several scenic byways and historic routes. Follow one of these designated routes to explore the patchwork countryside where pastureland, rolling hills and the Mississippi River create a truly picturesque landscape.

Visit pretty little villages and communities where residents treat guests like family. Attend the lively local festivals or hop on a riverboat for a romantic trip down the famous river.

Isle Casino Hotel - Waterloo - A Caesars Rewards Destination

Isle Casino Hotel - Waterloo - A Caesars Rewards Destination

3 out of 5
777 Isle of Capri Blvd Waterloo IA
$83 nightly
The price is $93 total per night from Jul 5 to Jul 6
$93 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Waterloo. Enjoy free WiFi, a casino, and a 24-hour fitness center. Our guests praise the helpful staff in our ...
8.2/10 Very Good! (1,004 reviews)
"Nice, clean large rooms. Comfortable bed. Food expensive but good. Only bad thing was the non-disclosed resort fee. I asked if there was one when I checked and was told there was not one. I got screwed !!!"

Reviewed on Jul 3, 2026

Isle Casino Hotel - Waterloo - A Caesars Rewards Destination
Hotel Julien Dubuque

Hotel Julien Dubuque

3.5 out of 5
200 Main Street Dubuque IA
$144 nightly
The price is $161 total per night from Jul 6 to Jul 7
$161 total
Jul 6 - Jul 7
Total with taxes and fees
Book a stay at this spa hotel in Dubuque. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the restaurant and the helpful staff in our ...
9.2/10 Wonderful! (1,869 reviews)
"Old world elegance with all the modern amenities. While breakfast was not free at the hotel, an extensive and reasonably priced breakfast is available on site at Caroline's. Their giant cinnamon roll is large enough to split with your partner...also super delicious!"

Reviewed on Jul 1, 2026

Hotel Julien Dubuque
Hyatt Place Iowa City Downtown

Hyatt Place Iowa City Downtown

3 out of 5
255 E Court St Iowa City IA
$112 nightly
The price is $125 total per night from Jul 12 to Jul 13
$125 total
Jul 12 - Jul 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Iowa City. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.2/10 Wonderful! (1,556 reviews)
"Nice"

Reviewed on Jul 2, 2026

Hyatt Place Iowa City Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
1850 Cabin Home - Large Backyard- 22' Movie Screen-Family-Event - Travelers

1850 Cabin Home - Large Backyard- 22' Movie Screen-Family-Event - Travelers

East Dubuque IL
Stay at this vacation home in East Dubuque. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker. Popular attractions Q Casino and Dubuque Star Brewing ...
9.6/10 Exceptional! (38 reviews)
"Great stay for family event"

Reviewed on Jun 29, 2026

1850 Cabin Home - Large Backyard- 22' Movie Screen-Family-Event - Travelers
Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos

3 out of 5
2372 N County Road 900 Nauvoo IL
Book a stay at this business-friendly condo in Nauvoo. Enjoy free WiFi, free parking, and a garden. Our guests praise the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (439 reviews)
"Nauvoo Villas have been well maintained and had everything that we needed for our recent family vacation to Nauvoo. It was a quick 5 minute drive from downtown."

Reviewed on Jun 19, 2026

Nauvoo Vacation Villas & Condos
Country setting 2-3 miles from the River, Luther College and downtown Decorah

Country setting 2-3 miles from the River, Luther College and downtown Decorah

Decorah IA
Book a stay at this family-friendly condo in Decorah. Enjoy free WiFi, a fitness center, and a garden. Popular attractions Lowell's Bridge and Sollien Wildlife ...
9.8/10 Exceptional! (199 reviews)
"This was a beautiful place. We really enjoyed it.The 10 AM checkout was rough for us. That was the only thing -we would’ve hoped for a 12 PM instead."

Reviewed on Jun 21, 2026

Country setting 2-3 miles from the River, Luther College and downtown Decorah
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Eastern Iowa attractions

Cities near Eastern Iowa

Explore a world of travel with Expedia