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St. Ann Vacation Rentals

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Check prices for these dates

In two weeks
Sep 18 - Sep 20
In two months
Oct 30 - Nov 1
In three months
Nov 27 - Nov 29
In four months
Dec 25 - Dec 27

Our top choices for St. Ann vacation rentals

A dining table set with plates, glasses, and a vase.

1. Cozy Cottage in the City

Cozy Cottage in the City
Saint Ann
9.2 out of 10, Wonderful, (5 reviews)
"This was a great house with comfortable beds and a very well equipped kitchen! The host was very accommodating and quick to respond. "
United States
Jennifer L.
$291 nightly
The price is $318
Sep 2 - Sep 3
Total with taxes and fees
Cozy Cottage in the City
A hotel lobby with a staircase, a reception desk, and a chandelier.

2. 2 Queen Beds | Non-Smoking, Kitchen

2 Queen Beds | Non-Smoking, Kitchen
Westport
9.8 out of 10, Exceptional, (38 reviews)
"Fantastic place!"
United States
Anonymous traveler
$61 nightly
The price is $70
Oct 1 - Oct 2
Total with taxes and fees
2 Queen Beds | Non-Smoking, Kitchen
A compact kitchen with white cabinets, a stainless steel refrigerator, a coffee maker, and a hanging pendant light.

3. Convenience 2 Bedroom House to Explore All of St Louis

Convenience 2 Bedroom House to Explore All of St Louis
University City
9.8 out of 10, Exceptional, (50 reviews)
"The house was immaculately clean and beds were extremely comfortable!"
United States
Anna M.
$246 nightly
The price is $266
Sep 27 - Sep 28
Total with taxes and fees
Convenience 2 Bedroom House to Explore All of St Louis
A bedroom with a bed, a dresser, and a nightstand. There is a hallway leading to a bathroom and a kitchen.

4. 6647 1W | Quaint Studio in Central St. Louis

6647 1W | Quaint Studio in Central St. Louis
Dogtown
8.2 out of 10, Very Good, (28 reviews)
"Great location, secure parking, overall great stay "
United States
Marcus
$140 nightly
The price is $140
Sep 2 - Sep 3
Total with taxes and fees
6647 1W | Quaint Studio in Central St. Louis
A modern kitchen with a stone accent wall, a central island, and pendant lighting.

5. Lots of Space! Central to St Charles and STL. Newly Remodeled. Large Backyard!

Lots of Space! Central to St Charles and STL. Newly Remodeled. Large Backyard!
Pinehurst
8.6 out of 10, Excellent, (36 reviews)
"Our family, daughters/husbands and grandmother stayed at the rental for a three day weekend. The rental was very clean, the kitchen has new appliances and is well equipped. The beds were very comfortable and everyone got good nice sleeps. "
United States
Steve H.
$623 nightly
The price is $713
Sep 7 - Sep 8
Total with taxes and fees
Lots of Space! Central to St Charles and STL. Newly Remodeled. Large Backyard!
A modern home office with a desk, chair, and computer monitor.

6. Spacious 2 Bedroom Townhome

Spacious 2 Bedroom Townhome
Saint Charles
8.0 out of 10, Very Good, (19 reviews)
"Quiet area and clean rooms"
United States
Chelsie H.
$283 nightly
The price is $312
Sep 7 - Sep 8
Total with taxes and fees
Spacious 2 Bedroom Townhome
A spacious living area with a dining table, sofa, and a large window with blinds.

7. Stunning Minimalist Gem | Fenced Backyard + W/D

Stunning Minimalist Gem | Fenced Backyard + W/D
Princeton Heights
10.0 out of 10, Exceptional, (23 reviews)
"I think the best part was that there were little hidden restaurants well within walking distance. It was an excellent stay, the accommodation were cozy."
United States
christine
$167 nightly
The price is $196
Sep 3 - Sep 4
Total with taxes and fees
Stunning Minimalist Gem | Fenced Backyard + W/D
A hotel room with a bed, a desk, a chair, a lamp, and a telephone.

8. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Westport
9.6 out of 10, Exceptional, (41 reviews)
"Great spot!"
United States
Anonymous traveler
$61 nightly
The price is $70
Oct 1 - Oct 2
Total with taxes and fees
1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

9. 6655 1N | Elegance Near the St. Louis Arch

6655 1N | Elegance Near the St. Louis Arch
Dogtown
7.8 out of 10, Good, (30 reviews)
"Great place to stay for the weekend. Cute and clean. Nice area with lot's of places in walking distance. I will definitely stay again."
United States
Brigitte B.
$150 nightly
The price is $150
Sep 14 - Sep 15
Total with taxes and fees
6655 1N | Elegance Near the St. Louis Arch
A hotel lobby with a staircase, a reception desk, and a seating area.

10. 2 Queen Beds | Mobil Access Tub Nsmk Kitchen

2 Queen Beds | Mobil Access Tub Nsmk Kitchen
Westport
9.8 out of 10, Exceptional, (45 reviews)
"Great place to stay!"
United States
Anonymous traveler
$61 nightly
The price is $70
Oct 1 - Oct 2
Total with taxes and fees
2 Queen Beds | Mobil Access Tub Nsmk Kitchen
A bedroom with a large bed, a bedside table, a chair, a desk, a mirror, and a door.

11. 6649 2E | Boutique Hotel Studio in Forest Park

6649 2E | Boutique Hotel Studio in Forest Park
Dogtown
8.0 out of 10, Very Good, (16 reviews)
"Friendly staff helped with my booking, check in was easy. Would stay again! "
United States
Marie
$142 nightly
The price is $142
Sep 3 - Sep 4
Total with taxes and fees
6649 2E | Boutique Hotel Studio in Forest Park
A spacious foyer with a grand staircase, a piano, and a large rug.

12. White House at Grand Central

White House at Grand Central
3.5 star property
Grand Center
8.4 out of 10, Very Good, (152 reviews)
"Staff was great and accommodating to my needs."
United States
Triman
$101 nightly
The price is $112
Sep 13 - Sep 14
Total with taxes and fees
White House at Grand Central
A row of multi-story buildings with commercial storefronts, including a cafe and a restaurant.

13. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (37 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
$187 nightly
The price is $206
Sep 6 - Sep 7
Total with taxes and fees
Historic Main Street Studio | Dog-Friendly
A modern kitchen with white cabinetry, stainless steel appliances, and a dining area with a wooden table and chairs.

14. Historic 1805 Main Street 2BR

Historic 1805 Main Street 2BR
St. Charles Historic District
9.6 out of 10, Exceptional, (42 reviews)
"The location is excellent. "
United States
McRay H.
$349 nightly
The price is $384
Sep 20 - Sep 21
Total with taxes and fees
Historic 1805 Main Street 2BR
A dining area with a wooden table, grey upholstered chairs, a bench, a patterned rug, a brick wall, a framed picture, and a potted plant.

15. Centrally located in the Tower Grove East neighborhood!

Centrally located in the Tower Grove East neighborhood!
Tower Grove East
9.8 out of 10, Exceptional, (171 reviews)
"Great place!"
United States
Arthur S.
$142 nightly
The price is $153
Sep 2 - Sep 3
Total with taxes and fees
Centrally located in the Tower Grove East neighborhood!
A bedroom with a bed, bedside table, and a large painting on the wall.

16. 6649 1E | Garden Style Studio Near Forest Park

6649 1E | Garden Style Studio Near Forest Park
Dogtown
8.0 out of 10, Very Good, (25 reviews)
"Very cute and cozy. Nice to be close to everything. "
United States
Dhgirlie H.
$140 nightly
The price is $140
Sep 14 - Sep 15
Total with taxes and fees
6649 1E | Garden Style Studio Near Forest Park
A modern living room with a grey sectional sofa, a wooden coffee table, and a staircase with wooden steps.

17. Near Streets of St Charles | 2 King Beds

Near Streets of St Charles | 2 King Beds
Saint Charles
9.0 out of 10, Wonderful, (12 reviews)
"We really enjoyed our stay. The house was clean, spacious, and very accommodating. We stayed for a dance competition and the proximity to the convention center was unbeatable. "
United States
Chloe
$283 nightly
The price is $312
Sep 7 - Sep 8
Total with taxes and fees
Near Streets of St Charles | 2 King Beds
A living room with a sofa, a coffee table, a TV, and a ceiling fan.

18. Starry Night | Steps to Tower Grove Park

Starry Night | Steps to Tower Grove Park
Tower Grove South
9.8 out of 10, Exceptional, (40 reviews)
"Clean, great location and thanks for quick responses"
United States
Martha E M.
$171 nightly
The price is $201
Sep 2 - Sep 3
Total with taxes and fees
Starry Night | Steps to Tower Grove Park
A modern kitchen with white cabinetry, a stainless steel refrigerator, and a granite countertop.

19. Historic 1908 Frenchtown Home

Historic 1908 Frenchtown Home
St. Charles Historic District
8.8 out of 10, Excellent, (26 reviews)
"Kitchen has a Kurig so be sure to get pods.The house is functional as a historic property but we really only used it as a place to sleep while in town for work. Getting ready with 3 people and one bath was slightly difficult as the bedroom didn't have a mirror so everyone required the bathroom, but the beds were comfy.It is a nice part of town, near the college and on a quiet one way street."
United States
Megan B.
$302 nightly
The price is $332
Sep 6 - Sep 7
Total with taxes and fees
Historic 1908 Frenchtown Home
A modern living room with a spiral staircase, a brick wall, a dining area, and a gray sofa.

20. Historic Main St 2BR | Steps to Shops

Historic Main St 2BR | Steps to Shops
St. Charles Historic District
9.4 out of 10, Exceptional, (42 reviews)
"This property has a nice renovation while keeping a lot of its original character. Very clean and comfortable beds as well. The location couldn’t be better! We really enjoyed our stay."
United States
William O.
$348 nightly
The price is $383
Sep 9 - Sep 10
Total with taxes and fees
Historic Main St 2BR | Steps to Shops
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Ann Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"This is my go to place when I need to travel to St. Louis for business. It’s in a safe location with many great places in the area to walk to. I find the ladies at the front counter, extremely helpful and welcoming."
Charles 2-night trip
Posted 2 hours ago
Clayton Plaza Hotel & Extended Stay

Find out more about St. Ann

Everything you need to know about St. Ann vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St. Ann vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Ann vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St. Ann vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Ann. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St. Ann in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $70 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St. Ann rentals

At Expedia, we put the best St. Ann vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St. Ann rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Ann vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Ann. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in St. Ann?

Yes, we give you a choice of vacation rentals where you'll be just 8.5 mi (13.7 km) from St. Louis Zoo, offering you a secluded option if you want a quiet place to stay. Our travelers say St. Ann has a good selection of restaurants and the bars. Make sure you have time to check out the baseball games and shopping during your trip.

What are some of the best vacation home rentals in St. Ann?

4BR 2BA Modern Family Home with Private Heated Inground Pool Open March 1-Nov11: This vacation home rental near St. Ann offers an outdoor pool, a fireplace, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a patio, a garden, and a selection of games so you can immerse yourself in your vacation.

How many vacation rentals are there in St. Ann?

With 10 Expedia vacation rentals, you're sure to find just the right place for your St. Ann stay.

What can I see and do in St. Ann?

While exploring the area, visit family-friendly sights like St. Louis Zoo, or get outside and enjoy nature at Lou Fusz Soccer Complex. While in the area, you can also visit popular places like St. Louis Union Station and Busch Stadium.

What are vacation rentals like in St. Ann?

Vacation rentals are private properties you can stay in for several days or more in St. Ann. Vacation rentals feature extras like kitchens and laundry facilities so you'll have all the conveniences of home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of security away from shared hotel elevators and busy front desks while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a great choice for a family getaway.