$468 Cheap Flights from Lisbon (LIS) to San Francisco (SFO)

View $468 flight on Fri, Oct 17, 2025Opens in a new window

Popular airlines from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO)

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Cheap Flights from Lisbon to San Francisco (LIS-SFO)

Prices were available within the past 7 days and start at $468 for one-way flights and $581 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Scandinavian Airlines
Wed, Nov 19 - Thu, Dec 4
LIS
Lisbon
SFO
San Francisco
$581 Roundtrip, found 16 hours ago
$581
Roundtrip
found 16 hours ago
Select Scandinavian Airlines flight, departing Wed, Nov 19 from Lisbon to San Francisco, returning Thu, Dec 4, priced at $581 found 16 hours ago
Lufthansa
Thu, Apr 2 - Thu, Apr 9
LIS
Lisbon
SFO
San Francisco
$705 Roundtrip, found 5 days ago
$705
Roundtrip
found 5 days ago
Select Lufthansa flight, departing Thu, Apr 2 from Lisbon to San Francisco, returning Thu, Apr 9, priced at $705 found 5 days ago
American Airlines
Sat, Dec 13 - Wed, Dec 31
LIS
Lisbon
SFO
San Francisco
$708 Roundtrip, found 1 day ago
$708
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Dec 13 from Lisbon to San Francisco, returning Wed, Dec 31, priced at $708 found 1 day ago
British Airways
Mon, Oct 27 - Mon, Nov 10
LIS
Lisbon
SFO
San Francisco
$709 Roundtrip, found 7 hours ago
$709
Roundtrip
found 7 hours ago
Select British Airways flight, departing Mon, Oct 27 from Lisbon to San Francisco, returning Mon, Nov 10, priced at $709 found 7 hours ago
Iberia
Thu, Sep 11 - Tue, Sep 16
LIS
Lisbon
SFO
San Francisco
$724 Roundtrip, found 3 days ago
$724
Roundtrip
found 3 days ago
Select Iberia flight, departing Thu, Sep 11 from Lisbon to San Francisco, returning Tue, Sep 16, priced at $724 found 3 days ago
Air Canada
Thu, Sep 18 - Tue, May 12
LIS
Lisbon
SFO
San Francisco
$726 Roundtrip, found 10 hours ago
$726
Roundtrip
found 10 hours ago
Select Air Canada flight, departing Thu, Sep 18 from Lisbon to San Francisco, returning Tue, May 12, priced at $726 found 10 hours ago
Swiss International Air Lines
Mon, Sep 8 - Mon, Sep 22
LIS
Lisbon
SFO
San Francisco
$732 Roundtrip, just found
$732
Roundtrip
just found
Select Swiss International Air Lines flight, departing Mon, Sep 8 from Lisbon to San Francisco, returning Mon, Sep 22, priced at $732 just found
United
Fri, Dec 26 - Sat, Jan 3
LIS
Lisbon
SFO
San Francisco
$749 Roundtrip, found 7 hours ago
$749
Roundtrip
found 7 hours ago
Select United flight, departing Fri, Dec 26 from Lisbon to San Francisco, returning Sat, Jan 3, priced at $749 found 7 hours ago
Delta
Tue, Sep 23 - Mon, Sep 29
LIS
Lisbon
SFO
San Francisco
$763 Roundtrip, found 10 hours ago
$763
Roundtrip
found 10 hours ago
Select Delta flight, departing Tue, Sep 23 from Lisbon to San Francisco, returning Mon, Sep 29, priced at $763 found 10 hours ago
Brussels Airlines
Wed, Nov 19 - Fri, Nov 28
LIS
Lisbon
SFO
San Francisco
$767 Roundtrip, found 11 hours ago
$767
Roundtrip
found 11 hours ago
Select Brussels Airlines flight, departing Wed, Nov 19 from Lisbon to San Francisco, returning Fri, Nov 28, priced at $767 found 11 hours ago

Find the cheapest month to fly from Lisbon (LIS) to San Francisco (SFO)

February is typically the cheapest month to fly

From $566 - $918 per traveler.

Graph displaying average flight prices per month

Alternative airports near San Francisco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Norman Y. Mineta San Jose Intl. SJC. Cheapest option available. Average driving time to city center is 50 minutes. Flights from $828
SJC
Norman Y. Mineta San Jose Intl.
Cheapest
Average driving time to city center50 min
Flights from $828
Flights from Lisbon (LIS) to San Francisco (SFO)
Origin airport
Humberto Delgado
Destination airport
San Francisco Intl.
Airlines serving
Aer Lingus, Air Canada, Air Europa, Air France, American Airlines, British Airways, Brussels Airlines, Delta, Emirates, Finnair, Iberia, JetBlue Airways, KLM, Lufthansa, Scandinavian Airlines, Swiss International Air Lines, TAP Portugal, Turkish Airlines, United, Virgin Atlantic
Roundtrip price
$580
Distance
5668 mi
Average flight time
12 hours 35 mins

Lisbon to San Francisco Flights

The cheapest times to fly from Lisbon to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lisbon to San Francisco are during the month of November. You can find some of the cheapest flights from Lisbon to San Francisco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lisbon to San Francisco

Sunday is one of the best days to book for cheap flights from Lisbon to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lisbon to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lisbon to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $468 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lisbon to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lisbon to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO) cost?
You can book cheap return flights starting from $851 from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a TAP Portugal flight leaving LIS on July 24 2025 and touching down at SFO. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from LIS to SFO?
The cheapest flights from LIS to SFO are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO)?
When flying out of Humberto Delgado Airport (LIS), you can get on a direct flight to San Francisco Intl. Airport (SFO) with TAP Portugal.
What is the cheapest airline that flies from LIS to SFO?
Take off from LIS to SFO with TAP Portugal. This airline currently offers the cheapest one-way fare on this route, starting at $741. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from LIS on September 20 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO)?
On average, there are 3 direct flights flying from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO) weekly. If you can't see one that fits your travel plans, think about taking a flight that has a layover. Filter your search on Expedia to include one or more stops and choose the next best alternative.
What are the most popular departure times for flights from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO)?
The 9 AM departures from LIS to SFO are the busiest. Greater demand means you'll likely pay more for these departures. If you want to save on your trip, choose a less crowded time to fly.
What day of the week has the most flights from LIS to SFO?
If you travel on a Friday, you'll get the widest range of options for flights from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO).
What is the earliest flight from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO)?
Humberto Delgado Airport (LIS)'s first flight to San Francisco Intl. Airport (SFO) leaves at approximately 9:10AM UTC+0. With a travel time of 13h 5m, you'll touch down at around 2:15PM UTC-8.
How long does it take to fly from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO)?
Flights from LIS to SFO have an average travel time of 13 hours and 1 minute. The total distance between the two is 5,700 mi.
What is the best time to fly from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO)?
To avoid potential delays on the Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO) route, aim to travel before 3 PM. Flights after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for San Francisco from Humberto Delgado Airport (LIS)?
San Francisco Intl. Airport (SFO) is the only airport in San Francisco with direct flights from Humberto Delgado Airport (LIS). Compare your options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO) last-minute?
Booking your plane ticket from LIS to SFO shortly before your trip is typically more expensive. However, if you're flexible with your departure dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book a LIS to SFO flight and hotel package?
You'll typically save money by booking a LIS to SFO flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After selecting your preferred accommodations and flights, consider adding extras such as activities, car rentals and tours.
Can I cancel or change the date of my flight from Humberto Delgado Airport (LIS) to San Francisco Intl. Airport (SFO)?
Usually, it's possible to reschedule or cancel your LIS to SFO flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.