Find spa resorts & hotels in Downtown South San Francisco, San Francisco from $175

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Top Downtown South San Francisco Resorts & Hotels with Spas

Kimpton Alton Fisherman's Wharf by IHG

4.5 star property
Fisherman's Wharf
9.2 out of 10, Wonderful, (1523)
"Great hotel with excellent service and a delicious restaurant. "
United States
Kerry
$149 nightly
The price is $175
Dec 22 - Dec 23
Total with taxes and fees
Kimpton Alton Fisherman's Wharf by IHG

Fairmont San Francisco

5.0 star property
Downtown San Francisco
9.0 out of 10, Wonderful, (1443)
"Beautiful hotel "
United States
Xandy
$260 nightly
The price is $306
Dec 14 - Dec 15
Total with taxes and fees
Fairmont San Francisco

Argonaut Hotel

4.5 star property
Fisherman's Wharf
9.4 out of 10, Exceptional, (1197)
"Fantastic location, clean, large rooms. The staff are great. Met all of our requests and gave great advice on things to do and see in SF."
United States
Daniel
$225 nightly
The price is $265
Dec 18 - Dec 19
Total with taxes and fees
Argonaut Hotel

Four Seasons Hotel San Francisco

5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1002)
"great room and staff. "
United States
chunguang
$315 nightly
The price is $371
Jan 8 - Jan 9, 2026
Total with taxes and fees
Four Seasons Hotel San Francisco

Casa Madrona Hotel & Spa

4.0 star property
Downtown
9.0 out of 10, Wonderful, (1003)
"Nice rooms and friendly staff. The location was excellent!"
United States
Brian
$292 nightly
The price is $330
Dec 22 - Dec 23
Total with taxes and fees
Casa Madrona Hotel & Spa

Claremont Resort & Club

5.0 star property
Claremont Hills
8.8 out of 10, Excellent, (1003)
"Everything about our stay with you was excellent !!!!"
United States
Gene
$396 nightly
The price is $451
Dec 14 - Dec 15
Total with taxes and fees
Claremont Resort & Club

Oceano Hotel and Spa

4.0 star property
El Granada
9.4 out of 10, Exceptional, (1006)
"Great resort"
United States
David
$305 nightly
The price is $341
Dec 10 - Dec 11
Total with taxes and fees
Oceano Hotel and Spa

1 Hotel San Francisco

5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (483)
"The staff was incredible and we loved all of the design touches in the room. The attention to detail was impressive. "
United States
Eric
$407 nightly
The price is $479
Dec 22 - Dec 23
Total with taxes and fees
1 Hotel San Francisco

The Beach House Hotel Half Moon Bay

3.5 star property
El Granada
9.2 out of 10, Wonderful, (987)
"We booked only one night in the hotel but we had a nice time and enjoyed it so much. We liked the complimentary breakfast and our ocean views. "
United States
Tamara
$296 nightly
The price is $345
Dec 10 - Dec 11
Total with taxes and fees
The Beach House Hotel Half Moon Bay

Cavallo Point

4.5 star property
Sausalito
9.2 out of 10, Wonderful, (980)
"Great place to escape near the city. Sebastian at the front desk was great with his customer service. "
United States
Birgit
$694 nightly
The price is $792
Jan 2 - Jan 3, 2026
Total with taxes and fees
Cavallo Point
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Downtown South San Francisco

Top Downtown South San Francisco attractions for a relaxing vacation

Downtown South San Francisco is not just a hub for business; it offers a unique blend of relaxation and exploration, perfect for travelers seeking spa hotels. Start your day with a stroll at the South San Francisco Historical Society Museum, where you can delve into the rich history of this charming city. For nature lovers, the nearby Bay Trail provides stunning views and a refreshing walk along the waterfront, ideal for unwinding before a spa treatment. If you're looking for a culinary adventure, visit the local farmers market, which showcases fresh, organic produce and artisan goods every Thursday, offering a taste of the region's bounty. Families will love the nearby San Francisco Zoo, which is not too far away and features a variety of exhibits that will keep both kids and adults entertained. After a day of exploration, retreat to your hotel, where you can indulge in luxurious spa services designed to rejuvenate your body and mind. Many hotels in the area feature on-site wellness centers and offer tailored spa packages that include everything from massages to skincare treatments, ensuring that your stay is as pampering as it is adventurous.

Top Downtown South San Francisco Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Downtown South San Francisco?
Forget the stress of everyday life and book yourself a hotel with a spa. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your weekend away.
What's there to see and do in Downtown South San Francisco?
Experience all that Downtown South San Francisco has to offer when you visit Chase Center, Oracle Park, and Pier 39. If you have a little extra time during your trip, you might want to check out SFO Museum and Artichoke Joe's Casino.
What is a Downtown South San Francisco spa hotel?
Spa hotels in Downtown South San Francisco provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.

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