Search Hotels in Santa Cruz

    price find illustration

    Upfront pricing

    Our total price for your stay includes taxes and fees
    deals illustration

    Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    bed illustration

    Be picky

    Search almost a million properties worldwide

Top Cities in Santa Cruz

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Compare 292 hotels in Santa Cruz with room rates, reviews, and availability. Most hotels are fully refundable.

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
9.0 out of 10, Wonderful, (324)
"Always an amazing hotel "
$131 nightly
The price is $131
Sep 10 - Sep 11
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
9.0 out of 10, Wonderful, (191)
"Our stay was comfortable and the service was great!"
$119 nightly
The price is $119
Aug 29 - Aug 30
Marriott Santa Cruz de la Sierra Hotel

Camino Real Hotel

4.5 star property
8.8 out of 10, Excellent, (396)
"Great Hotel, had a great time ."
$140 nightly
The price is $140
Sep 15 - Sep 16
Camino Real Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
9.2 out of 10, Wonderful, (248)
"Nice hotel "
$103 nightly
The price is $103
Aug 22 - Aug 23
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Sun Hotel

3.5 star property
8.4 out of 10, Very Good, (311)
"Todo excelente "
$97 nightly
The price is $97
Aug 21 - Aug 22
Sun Hotel

Ibis Santa Cruz DE LA Sierra

3.0 star property
9.6 out of 10, Exceptional, (51)
"Basic hotel with very friendly staff. The staff is superb Very nice neighborhood!!!nice shopping and great restaurants !"
$43 nightly
The price is $43
Sep 4 - Sep 5
Ibis Santa Cruz DE LA Sierra

Hotel Cortez

3.5 star property
9.0 out of 10, Wonderful, (111)
"I love the pool and garden area and ALL of the staff are so friendly and helpful "
$101 nightly
The price is $101
Aug 22 - Aug 23
Hotel Cortez

Novotel Santa Cruz De La Sierra

5.0 star property
9.2 out of 10, Wonderful, (95)
"Nice hotel, modern, with pool, good restaurant. Would stay here again without no doubt. "
$107 nightly
The price is $107
Aug 24 - Aug 25
Novotel Santa Cruz De La Sierra

Lido Hotel

3.0 star property
9.0 out of 10, Wonderful, (24)
"Clean, with AC and both hot and cold water. "
$41 nightly
The price is $41
Sep 4 - Sep 5
Lido Hotel

Apart Hotel Premium Suites Santa Cruz

3.5 star property
8.6 out of 10, Excellent, (89)
"Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. "
Apart Hotel Premium Suites Santa Cruz

Delfines Collection Hotel By Mercure

3.5 star property
9.0 out of 10, Wonderful, (60)
"Excellent place to stay!"
$41 nightly
The price is $41
Aug 24 - Aug 25
Delfines Collection Hotel By Mercure

TRYP by Wyndham Santa Cruz

4.0 star property
9.2 out of 10, Wonderful, (131)
"Nice stay with good service "
$109 nightly
The price is $109
Aug 21 - Aug 22
TRYP by Wyndham Santa Cruz

Swissôtel Santa Cruz De La Sierra

4.5 star property
9.2 out of 10, Wonderful, (77)
"Beautiful hotel"
$104 nightly
The price is $104
Aug 24 - Aug 25
Swissôtel Santa Cruz De La Sierra

Hotel LP Santa Cruz Centro

3.0 star property
8.0 out of 10, Very Good, (280)
"Clean, friendly staff"
$41 nightly
The price is $41
Aug 27 - Aug 28
Hotel LP Santa Cruz Centro

Hotel LP Equipetrol

3.5 star property
8.2 out of 10, Very Good, (199)
"Nice place to stay"
Hotel LP Equipetrol

Hotel G

3.5 star property
7.8 out of 10, Good, (104)
"Excelente Hotel "
Hotel G

Premium Suites Deluxe Aparthotel Equipetrol

3.5 star property
9.0 out of 10, Wonderful, (73)
"Good price, great hotel!"
$44 nightly
The price is $44
Aug 21 - Aug 22
Premium Suites Deluxe Aparthotel Equipetrol

Chairú Eco Hotel

3.5 star property
9.4 out of 10, Exceptional, (39)
"Nice and clean hotel "
Chairú Eco Hotel

Hotel Maywa

4.0 star property
9.2 out of 10, Wonderful, (10)
"Es mi segunda vez hospedandome en el hotel, la atención excelente, desayuno muy rico y variado, la habitacion tiene cama muy comoda y una excelente limpieza"
$49 nightly
The price is $49
Aug 21 - Aug 22
Hotel Maywa

Terranova Suites

3.5 star property
8.0 out of 10, Very Good, (90)
"The pictures of the property have to be from a decade ago. This place it is dirty and in poor shape. "
$47 nightly
The price is $47
Aug 25 - Aug 26
Terranova Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Santa Cruz

Showing deals for:Aug 29 - Aug 31
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Hotel Reviews

Frequently asked questions

How much do hotels in Santa Cruz cost?
The season and factors like school holidays, Christmas and Easter can influence the price of a hotel in Santa Cruz. You can find cheap options from $41 in a few different ways on Expedia. First, key in the dates you'd like to go on vacation, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most inexpensive options appear at the top.
When is the best time to go to Santa Cruz?
If you're thinking of visiting in summer, reserve your Santa Cruz hotel between December and February. Temperatures during the summer here range from 72ºF to 88ºF. Santa Cruz has an oceanic climate, so pack appropriately.
Are there any luxury hotels in Santa Cruz?
Expedia has got some terrific stays for an indulgent escape in Santa Cruz, Santa Cruz, such as Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Check in and make use of amenities like concierge services, a garden and complimentary breakfast. Alternatively, treat yourself at Radisson Hotel Santa Cruz.
What are the top all-inclusive hotels in Santa Cruz?
If you're looking for a relaxed and worry-free escape, throw your bags down at Prince Hotel. Generally including your drinks, food and some recreational activities in the flat upfront rate, it's one of the best options for an all-inclusive retreat in Santa Cruz.
How can I find cheap hotels in Santa Cruz?
Discover inexpensive hotels with minimal effort by making use of our filter tool. Choose the "Price per night" box to view low-cost options in Santa Cruz. Another way is to take a look at our cheap hotels in Santa Cruz page. The lowest price available starts from $41 per night.
What are the best hotels in Santa Cruz for families?
Cosmopolitano Hotel Boutique is one of the top-rated hotels for families, located in Santa Cruz, Santa Cruz. Book here and take advantage of conveniences such as complimentary breakfast and a cafe. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favorite where kiddos are welcome. For more hotel options, fine-tune your search results by selecting "Family friendly" under the "Traveler experience" filter heading.
Why should I book my Santa Cruz hotel with Expedia?
Expedia makes booking accommodations in Santa Cruz as simple as swiping right for your dream adventure. First, there's the extensive choice and incredible prices. Then, there's our online Help Center, which operates around-the-clock. Plus, when you become a member of our One Key™ rewards program, you can earn OneKeyCash™* and redeem it on eligible flights, hotels, activities and more. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.