Find hotels in OST - South Union, Houston

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Discover OST - South Union hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Chic Med Center Retreat w Yard

2.0 star property
OST - South Union
$534 nightly
The price is $625
Dec 5 - Dec 6
Total with taxes and fees
Chic Med Center Retreat w Yard

The Whitehall Houston

4.0 star property
Houston Central Business District, 4.4 mi from OST - South Union
8.6 out of 10, Excellent, (1895)
"Great stay."
United States
Anita
$111 nightly
The price is $130
Jan 1 - Jan 2, 2026
Total with taxes and fees
The Whitehall Houston

The Lancaster Hotel

4.0 star property
Downtown Houston, 4.6 mi from OST - South Union
9.8 out of 10, Exceptional, (1000)
"Great amenities and hospitality "
United States
Varun
$198 nightly
The price is $232
Dec 24 - Dec 25
Total with taxes and fees
The Lancaster Hotel

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4.0 star property
8.4 mi from OST - South Union
8.2 out of 10, Very Good, (3020)
"Wonderful property will be booking again"
United States
Tyanna
$126 nightly
The price is $147
Jan 2 - Jan 3, 2026
Total with taxes and fees
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

Hyatt Regency Houston/Galleria

4.0 star property
The Galleria, 8.3 mi from OST - South Union
9.0 out of 10, Wonderful, (1159)
"Confortable bed, quiet ron and nice breakfast!"
United States
Juan
$155 nightly
The price is $181
Dec 12 - Dec 13
Total with taxes and fees
Hyatt Regency Houston/Galleria

Blossom Hotel Houston, Curio Collection by Hilton

4.0 star property
Texas Medical Center, 3.8 mi from OST - South Union
9.0 out of 10, Wonderful, (3616)
"Everything about our stay was excellent. "
United States
Clarence
$132 nightly
The price is $154
Jan 2 - Jan 3, 2026
Total with taxes and fees
Blossom Hotel Houston, Curio Collection by Hilton

The Royal Sonesta Houston Galleria

4.0 star property
The Galleria, 7.9 mi from OST - South Union
8.4 out of 10, Very Good, (1434)
"Great place to stay!"
United States
Curtis
$129 nightly
The price is $151
Dec 19 - Dec 20
Total with taxes and fees
The Royal Sonesta Houston Galleria

Omni Houston Hotel

4.0 star property
8.5 mi from OST - South Union
9.0 out of 10, Wonderful, (1002)
"Great location! "
United States
Fletcher
$162 nightly
The price is $189
Dec 5 - Dec 6
Total with taxes and fees
Omni Houston Hotel

Hyatt Place Houston Medical Center

3.0 star property
Texas Medical Center, 3.9 mi from OST - South Union
9.2 out of 10, Wonderful, (2156)
"Nice hotel, excellent rooms with comfy beds! Only stayed one night but definitely a nice place"
United States
Carey
$117 nightly
The price is $137
Dec 15 - Dec 16
Total with taxes and fees
Hyatt Place Houston Medical Center

Hyatt Regency Houston West

3.5 star property
18 mi from OST - South Union
8.4 out of 10, Very Good, (1231)
"Great room and staff."
United States
Brad
$107 nightly
The price is $125
Dec 21 - Dec 22
Total with taxes and fees
Hyatt Regency Houston West

Hilton Houston Plaza/Medical Center

4.5 star property
4.1 mi from OST - South Union
8.4 out of 10, Very Good, (1718)
"Clean rooms, comfortable bed, & friendly staff"
United States
Thomas
$95 nightly
The price is $111
Dec 21 - Dec 22
Total with taxes and fees
Hilton Houston Plaza/Medical Center

Club Quarters Hotel Downtown, Houston

4.0 star property
Houston Central Business District, 4.4 mi from OST - South Union
8.4 out of 10, Very Good, (3920)
"Hotel was beautiful, room was great for the price"
United States
Sonya
$84 nightly
The price is $98
Dec 6 - Dec 7
Total with taxes and fees
Club Quarters Hotel Downtown, Houston

Hilton Americas-Houston

4.0 star property
3.9 mi from OST - South Union
9.4 out of 10, Exceptional, (1593)
"Clean, great location and super convenient food options!"
United States
Valerie
$150 nightly
The price is $176
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hilton Americas-Houston

Hyatt House Houston Medical Center

3.0 star property
Texas Medical Center, 3.9 mi from OST - South Union
9.2 out of 10, Wonderful, (1176)
"I had a great stay! I travel to Houston several times a year and this is one of my favorite places to stay."
United States
Star
$117 nightly
The price is $137
Dec 22 - Dec 23
Total with taxes and fees
Hyatt House Houston Medical Center

Holiday Inn Express & Suites Houston - Memorial City Centre by IHG

2.5 star property
14.6 mi from OST - South Union
8.8 out of 10, Excellent, (1000)
"Clean, quiet and will return "
United States
Lauren
$96 nightly
The price is $112
Dec 14 - Dec 15
Total with taxes and fees
Holiday Inn Express & Suites Houston - Memorial City Centre by IHG

Holiday Inn Houston Downtown by IHG

3.0 star property
Houston Central Business District, 4.2 mi from OST - South Union
8.6 out of 10, Excellent, (1589)
"Accommodating staff and clean room and shuttle services and great location. Room had a nice view."
United States
Add a new
$91 nightly
The price is $107
Dec 22 - Dec 23
Total with taxes and fees
Holiday Inn Houston Downtown by IHG

Moxy Houston Downtown

3.0 star property
Downtown Houston, 4.6 mi from OST - South Union
8.8 out of 10, Excellent, (648)
"Great hotel "
United States
Norma
$74 nightly
The price is $87
Dec 26 - Dec 27
Total with taxes and fees
Moxy Houston Downtown

Hilton Garden Inn Houston Medical Center, TX

3.0 star property
Texas Medical Center, 3 mi from OST - South Union
9.4 out of 10, Exceptional, (1018)
"Clean room and nice staff"
Canada
Guillermo
$103 nightly
The price is $121
Dec 22 - Dec 23
Total with taxes and fees
Hilton Garden Inn Houston Medical Center, TX

Home2 Suites by Hilton at the Galleria

3.0 star property
Greater Uptown, 8.1 mi from OST - South Union
8.8 out of 10, Excellent, (985)
"Nice place "
United States
Shaojun
$106 nightly
The price is $124
Dec 14 - Dec 15
Total with taxes and fees
Home2 Suites by Hilton at the Galleria

Sonesta ES Suites Houston Galleria

3.0 star property
The Galleria, 8.2 mi from OST - South Union
8.2 out of 10, Very Good, (1141)
"Nice stay"
United States
Steven
$109 nightly
The price is $127
Jan 1 - Jan 2, 2026
Total with taxes and fees
Sonesta ES Suites Houston Galleria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in OST - South Union

Find the best OST - South Union areas and neighborhoods for the activities you enjoy most.

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Northside

While you're in Northside, take in top sights like The Heights Theater or Greenspoint Mall, and hop on the metro to see more the city at Northline Transit Center/HCC Station or Melbourne/North Lindale Station.

Top OST - South Union Hotel Reviews

Frequently asked questions

What are the best hotels in OST - South Union that travelers recommend?
The Hilton Garden Inn Houston Medical Center is a great choice for travelers, boasting a great rating of 9.4. This hotel offers an outdoor pool great for family fun, along with a fitness center available 24/7 for those who like to stay active. Business travelers will appreciate the well-equipped meeting rooms and a 24-hour business center, ensuring productivity while on the road. The pet-friendly policy makes it a great option for those who want to bring their furry friends along.

Families will find the Home2 Suites by Hilton Houston Medical Center an excellent fit, rated at 9.2. With spacious suites that include kitchenettes, preparing meals for picky eaters is a breeze. The outdoor pool invites relaxation after a day of adventure, and the complimentary hot breakfast is a fantastic way to fuel up for outings. Plus, the hotel's pet-friendly amenities and free area shuttle add convenience for families and pets alike.

For those seeking a blend of comfort and convenience, the Hilton University of Houston, rated 8.8, has a friendly setting with a variety of suites designed for relaxation. Guests can enjoy designer toiletries and premium bedding for a touch of luxury. The hotel also features a pool that's great for kids, along with a business center and meeting space for professionals needing to stay connected.
What are the best spa hotels in OST - South Union?
For a rejuvenating stay, the Hilton Garden Inn Houston Medical Center is an excellent choice, boasting a great rating of 9.4. This hotel is popular for its accessible spa amenities, making it a convenient option for travelers seeking relaxation during their visit. With a inviting space and attentive service, guests can easily unwind and recharge before or after exploring the vibrant city of Houston.
What hotels in OST - South Union offer free breakfast?
Home2 Suites by Hilton Houston Medical Center is a fantastic choice for travelers looking for a comfortable stay with family-friendly amenities. Rated 9.2 by guests, this hotel offers a delightful buffet breakfast included in your stay, ensuring everyone starts the day energized and ready for adventure. Families will appreciate the outdoor pool, complete with sun loungers for relaxation while the kids splash around, and the convenience of having kitchen facilities in each suite for easy meal preparation.

Additionally, the hotel provides a complimentary area shuttle, making it simple to explore local attractions without the hassle of parking. For those traveling with pets, Home2 Suites is welcoming to furry friends, offering designated areas for their enjoyment.
What are the most romantic hotels in OST - South Union for couples?
The Vibe 3bd X 4b in Downtown Houston is a delightful option for couples seeking a romantic getaway, boasting a great rating of 9.6. This charming accommodation features a spacious balcony where you can enjoy a sunset with your partner, creating the superb atmosphere for intimate moments.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right OST - South Union hotel for you.
How can I save on a OST - South Union hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on OST - South Union hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a OST - South Union hotel?
Hotel prices in OST - South Union often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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