Title: Port Isabel Vacation Rentals from $309: Search Short-Term Rentals | Expedia.com [Port Isabel Travel Guide](https://expedia.com/Port-Isabel.dx184007)[Hotels in Port Isabel](https://expedia.com/Port-Isabel-Hotels.d184007.Travel-Guide-Hotels)[Flights to Port Isabel](https://expedia.com/Cheap-Flights-To-Port-Isabel.d184007.Travel-Guide-Flights)[Things to do in Port Isabel](https://expedia.com/Things-To-Do-In-Port-Isabel.d184007.Travel-Guide-Activities)[Car Rentals in Port Isabel](https://expedia.com/Car-Rentals-In-Port-Isabel.d184007.Car-Rental-Guide)[Port Isabel Vacation Packages](https://expedia.com/Port-Isabel.d184007.Destination-Travel-Guides) ![Port Isabel](https://images.trvl-media.com/place/184007/bd9c1ec3-f2dc-45ab-829d-76b09b3a2356.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/184007/bd9c1ec3-f2dc-45ab-829d-76b09b3a2356.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check prices for these dates In two weeks [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=184007&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=184007&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=184007&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jun 19 - Jun 21](https://www.expedia.com/Hotel-Search?regionId=184007&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Port Isabel vacation rentals ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100650000/100644800/100644783/53db6add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/101000000/100650000/100644800/100644783/e8ddd204.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100650000/100644800/100644783/2832bf29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![A heated pool](https://images.trvl-media.com/lodging/101000000/100650000/100644800/100644783/f3950874_edited_fdea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Orion C | Cozy 1BR Retreat w/ Pool & Grill [](https://www.expedia.com/Port-Isabel-Hotels-Casa-Cactus-C-Heated-Pool.h100644783.Hotel-Information) Port Isabel 10/10 Exceptional (1 review) $233 nightly $268 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-Casa-Cactus-C-Heated-Pool.h100644783.Hotel-Information) ![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/122000000/121560000/121556100/121556051/a1f9516f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/122000000/121560000/121556100/121556051/d0cbb3ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/122000000/121560000/121556100/121556051/8351fabb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/122000000/121560000/121556100/121556051/944cd3d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Waterfront With Deck [](https://www.expedia.com/Port-Isabel-Hotels-Cozy-Waterfront-With-Deck.h121556051.Hotel-Information) Port Isabel $277 nightly $319 total Mar 3 - Mar 4 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-Cozy-Waterfront-With-Deck.h121556051.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/84000000/83760000/83751200/83751136/49da3e72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/84000000/83760000/83751200/83751136/w1992h1333x0y0-005f7cb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/84000000/83760000/83751200/83751136/9f15cd4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/84000000/83760000/83751200/83751136/ccd242fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### LIV Resort: Cottage with Private Jacuzzi/Pet Friendly [](https://www.expedia.com/Port-Isabel-Hotels-1st-Floor-Ocean-Front-Condo-With-Beach-View.h83751136.Hotel-Information) Port Isabel 9.0/10 Wonderful (4 reviews) "Overall we had a nice trip. Location was good, close to food, shopping, and South Padre beaches. Home is very small for 3 adults and 1 dog. Beds were not so comfy but hot tub was a nice added bonus." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveler $587 nightly $601 total Mar 4 - Mar 5 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-1st-Floor-Ocean-Front-Condo-With-Beach-View.h83751136.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/111000000/110310000/110305200/110305179/1e3b71d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books, stereo](https://images.trvl-media.com/lodging/111000000/110310000/110305200/110305179/498182eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/111000000/110310000/110305200/110305179/196e44c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/111000000/110310000/110305200/110305179/8d656212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Family&Dog Friendly Home w/fenced yard 5min walk to town 7min drive to SPI Beach [](https://www.expedia.com/Port-Isabel-Hotels-FamilyDog-Friendly-Home-Wfenced-Yard-5min-Walk-To-Town-7min-Drive-To-SPI-Beach.h110305179.Hotel-Information) Port Isabel 9.8/10 Exceptional (13 reviews) "The house has a great location that we were able to walk to dinner and shop." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) donna D. $352 nightly $371 total Feb 26 - Feb 27 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-FamilyDog-Friendly-Home-Wfenced-Yard-5min-Walk-To-Town-7min-Drive-To-SPI-Beach.h110305179.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/120000000/119150000/119149300/119149277/aa0550f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/120000000/119150000/119149300/119149277/603cf532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119150000/119149300/119149277/99a5b5d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119150000/119149300/119149277/ce046796.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront 2 Bedroom 3 Beds Cottage [](https://www.expedia.com/Port-Isabel-Hotels-Waterfront-2-Bedroom-Cottage.h119149277.Hotel-Information) Port Isabel 10/10 Exceptional (2 reviews) "Very clean, host was very quick to answer all questions I had before the trip and during. I had to make a few changes to my reservation and he was very pleasant and accommodating. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monica F. $404 nightly $425 total Mar 10 - Mar 11 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-Waterfront-2-Bedroom-Cottage.h119149277.Hotel-Information) ![Condo, Multiple Beds, Balcony, Ocean View | Property grounds](https://images.trvl-media.com/lodging/78000000/77850000/77841800/77841714/b4a60cec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, Multiple Beds, Balcony, Ocean View | Living area | TV](https://images.trvl-media.com/lodging/78000000/77850000/77841800/77841714/a175ddbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, Multiple Beds, Balcony, Ocean View | Interior](https://images.trvl-media.com/lodging/78000000/77850000/77841800/77841714/5a2778ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/78000000/77850000/77841800/77841714/4ad28298.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bungalow Tarvana-#1 [](https://www.expedia.com/Port-Isabel-Hotels-Bungalow-Tarvana-1.h77841714.Hotel-Information) Port Isabel 8.0/10 Very Good (2 reviews) "The property was nice and in a great location for walking. The surrounding area was a little run down… The point of contact by the name of Jim was rude but we didn’t have any use for him after we arrived at the location. On Expedia, it states that tenants will receive an email with the code to the door at the 24 hour mark. We did not receive the code until two hours before our arrival. This was uncomfortable for us as we had to drive six hours to the location. I called Jim in the early am and... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) April $365 nightly $420 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-Bungalow-Tarvana-1.h77841714.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121560000/121557900/121557821/f503f6d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/122000000/121560000/121557900/121557821/6269c99f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121560000/121557900/121557821/05e09b45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121560000/121557900/121557821/c13f502a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Canal Front Retreat w/ Boat Dock & Coastal Views [](https://www.expedia.com/Port-Isabel-Hotels-The-Pompano-House-Sum.h121557821.Hotel-Information) Port Isabel 9.8/10 Exceptional (25 reviews) "What a wonderful and relaxing stay!!!! We enjoyed the house so much and fishing off the dock! Location was perfect! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle C. $433 nightly $494 total Mar 3 - Mar 4 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-The-Pompano-House-Sum.h121557821.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/91000000/90060000/90057700/90057688/6f43a5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, a heated pool](https://images.trvl-media.com/lodging/91000000/90060000/90057700/90057688/66d4df62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/91000000/90060000/90057700/90057688/c463b41c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, wheelchair access](https://images.trvl-media.com/lodging/91000000/90060000/90057700/90057688/524d2f53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### See Dolphins From Your Private Deck with This Beautiful Property! #170 [](https://www.expedia.com/Port-Isabel-Hotels-See-Dolphins-From-Your-Private-Deck-With-This-Beautiful-Property.h90057688.Hotel-Information) Port Isabel 10/10 Exceptional (2 reviews) "Very good place with awesome views to the intercoastal channel. good size patio. Only downside is bedroom 2 is half bath. All in all a very good & will look forward to coming back.." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan R. $516 nightly $572 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-See-Dolphins-From-Your-Private-Deck-With-This-Beautiful-Property.h90057688.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111060000/111058300/111058251/9b6d98c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/112000000/111060000/111058300/111058251/2f926480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111060000/111058300/111058251/db4bac8d_edited_b137.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/112000000/111060000/111058300/111058251/e807c2b1_edited_59f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Waterfront Bungalow " Fisherman's Paradise [](https://www.expedia.com/Port-Isabel-Hotels-New-Waterfront-Bungalow-Fishermans-Paradise.h111058251.Hotel-Information) Port Isabel 10/10 Exceptional (1 review) "Good stay will do it again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John W. $377 nightly $430 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-New-Waterfront-Bungalow-Fishermans-Paradise.h111058251.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121560000/121557900/121557896/35d732cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/122000000/121560000/121557900/121557896/cd56f701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/122000000/121560000/121557900/121557896/fd5e8e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121560000/121557900/121557896/b5eb0d1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern Waterfront Escape with a Deck & BBQ Grill [](https://www.expedia.com/Port-Isabel-Hotels-Cozy-Waterfront-With-Deck.h121557896.Hotel-Information) Port Isabel 10/10 Exceptional (1 review) "Some friends and I stayed at this property while going fishing in the area. If you’re outback looks very convenient and save us a lot of time from having to launch elsewhere. The interior is very well furnished and comfortable. Stores, restaurants, and whatever else you need is within a very short drive of the property. Will stay here again on our next fishing trip to the area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert A. $289 nightly $329 total Mar 3 - Mar 4 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-Cozy-Waterfront-With-Deck.h121557896.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/105000000/104340000/104331500/104331414/ade5c3be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/105000000/104340000/104331500/104331414/cfe113b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, a heated pool](https://images.trvl-media.com/lodging/105000000/104340000/104331500/104331414/4c2cc5d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/105000000/104340000/104331500/104331414/bc60fab6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Available for Spring! Casa Azul Cozy One Bedroom 607 [](https://www.expedia.com/Port-Isabel-Hotels-Casa-Azul-Cozy-One-Bedroom-607.h104331414.Hotel-Information) Port Isabel 9.4/10 Exceptional (3 reviews) "It was ok. We were called by the host the day before arrival that the place we were supposed to stay needed new blinds and she would put us up in another spot. It was ok but needed some repairs inside. Probably would not stay there again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda B. $437 nightly $485 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-Casa-Azul-Cozy-One-Bedroom-607.h104331414.Hotel-Information) ![Fridge, stovetop, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/107000000/106470000/106463500/106463480/da61fe4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106470000/106463500/106463480/520e1cd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/107000000/106470000/106463500/106463480/e15dda08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106470000/106463500/106463480/2b733e59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Views of Space X from beautiful Lakeside Haven 620 [](https://www.expedia.com/Port-Isabel-Hotels-.h106463480.Hotel-Information) Port Isabel $468 nightly $518 total Feb 26 - Feb 27 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-.h106463480.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/106000000/105770000/105769800/105769709/a64e1f37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, table tennis](https://images.trvl-media.com/lodging/106000000/105770000/105769800/105769709/d0074b70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, a heated pool](https://images.trvl-media.com/lodging/106000000/105770000/105769800/105769709/14e7ab32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/106000000/105770000/105769800/105769709/544a16ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Available for Spring! 186 Little Breeze Cottage on the Water [](https://www.expedia.com/Port-Isabel-Hotels-186-Cozy-Cottage-On-The-Water.h105769709.Hotel-Information) Port Isabel 7.4/10 Good (3 reviews) "A comfortable cottage with all the amenities, it even had a dishwasher. The kitchen was stocked with everything we needed if we abated to cook (which wasn’t often ). Andrea managed the place and she made sure we had everything we needed, very nice!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maribeth R. $437 nightly $485 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-186-Cozy-Cottage-On-The-Water.h105769709.Hotel-Information) ![House | 4 bedrooms, Internet](https://images.trvl-media.com/lodging/122000000/121400000/121391200/121391179/307cd1cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | 4 bedrooms, Internet](https://images.trvl-media.com/lodging/122000000/121400000/121391200/121391179/11eda462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | 4 bedrooms, Internet](https://images.trvl-media.com/lodging/122000000/121400000/121391200/121391179/ed068a16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | 4 bedrooms, Internet](https://images.trvl-media.com/lodging/122000000/121400000/121391200/121391179/9bd774b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bayside Paradise 4BR Home w Patio Games Room [](https://www.expedia.com/Port-Isabel-Hotels-Bayside-Paradise-4BR-Home-W-Patio-Games-Room.h121391179.Hotel-Information) Port Isabel $454 nightly $522 total Mar 3 - Mar 4 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-Bayside-Paradise-4BR-Home-W-Patio-Games-Room.h121391179.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/112000000/111660000/111652700/111652659/9f661bfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/112000000/111660000/111652700/111652659/166605aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111660000/111652700/111652659/28457917.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, a heated pool](https://images.trvl-media.com/lodging/112000000/111660000/111652700/111652659/9b2dc775.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avail for Spring! Mermaid Manor- Cozy Waterfront Getaway [](https://www.expedia.com/Port-Isabel-Hotels-Cozy-Waterfront-Getaway-In-Port-Isabel-1-Bedroom.h111652659.Hotel-Information) Port Isabel 10/10 Exceptional (1 review) $461 nightly $512 total Mar 5 - Mar 6 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-Cozy-Waterfront-Getaway-In-Port-Isabel-1-Bedroom.h111652659.Hotel-Information) ![4 bedrooms, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/121000000/120680000/120677500/120677465/9d9baf41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120680000/120677500/120677465/3f405aa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/121000000/120680000/120677500/120677465/8bd09710.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/121000000/120680000/120677500/120677465/d7194b14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bayside Waterfront Home with Private Patio [](https://www.expedia.com/Port-Isabel-Hotels-Bayside-Paradise-4BR-Home-W-Patio-Games-Room.h120677465.Hotel-Information) Port Isabel 8.0/10 Very Good (1 review) "Nice home great location and beautiful view. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joe G. $489 nightly $558 total Mar 3 - Mar 4 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-Bayside-Paradise-4BR-Home-W-Patio-Games-Room.h120677465.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/100000000/99950000/99946100/99946054/w1042h822x0y3-f123d2b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/100000000/99950000/99946100/99946054/784e1076.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/100000000/99950000/99946100/99946054/34ddf59e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sport court](https://images.trvl-media.com/lodging/100000000/99950000/99946100/99946054/40c5bad4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bayfront Cottage - Pool - Hot Tub - Close to Beach [](https://www.expedia.com/Port-Isabel-Hotels-Bayfront-Cottage-Pool-Hot-Tub-Close-To-Beach.h99946054.Hotel-Information) Port Isabel 10/10 Exceptional (4 reviews) "Really nice, clean, safe, well-equipped, private baths, etc. Perfect for a small group of friends or family. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erin B. $434 nightly $492 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-Bayfront-Cottage-Pool-Hot-Tub-Close-To-Beach.h99946054.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96910000/96901200/96901178/c8f4fdee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96910000/96901200/96901178/c3a0a160.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/97000000/96910000/96901200/96901178/b36bda28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96910000/96901200/96901178/4e39349c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Available for Spring! Lazy Days Sea Cottage #1015 [](https://www.expedia.com/Port-Isabel-Hotels-Lazy-Days-Sea-Cottage-1015.h96901178.Hotel-Information) Port Isabel $630 nightly $696 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-Lazy-Days-Sea-Cottage-1015.h96901178.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/84000000/83480000/83477900/83477828/604f37ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83480000/83477900/83477828/1fe5724e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, stereo](https://images.trvl-media.com/lodging/84000000/83480000/83477900/83477828/ad92d64b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83480000/83477900/83477828/a79fe040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ★8 Mins to SPI Beach Spacious 3BR + Backyard☆ [](https://www.expedia.com/Port-Isabel-Hotels-8-Min-To-Beach-Wonderful-Stay-At-Modern-3BR.h83477828.Hotel-Information) Port Isabel 7.6/10 Good (4 reviews) "Clean an a really good spot you guys won’t regret staying here I promise" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ozzy H. $370 nightly $390 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-8-Min-To-Beach-Wonderful-Stay-At-Modern-3BR.h83477828.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/108000000/107300000/107290400/107290400/9d0c62ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107300000/107290400/107290400/4ae9229c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/108000000/107300000/107290400/107290400/33e5a0b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107300000/107290400/107290400/85a32a1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ♥︎Spacious 3BR Home Near SPI Beach & Restaurants♡ [](https://www.expedia.com/Port-Isabel-Hotels-Stylish-3BR-Home-8-Min-Drive-To-Beach.h107290400.Hotel-Information) Port Isabel 10/10 Exceptional (1 review) $351 nightly $370 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Port-Isabel-Hotels-Stylish-3BR-Home-8-Min-Drive-To-Beach.h107290400.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-11&endDate=2026-03-12®ionId=184007&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=VR_SPRING_PROMO_184007) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.com/Hotel-Search?destination=Port+Isabel%2C+Texas%2C+United+States+of+America®ionId=184007&latLong=26.073421%2C-97.208595&adults=2&startDate=2026-05-26&d1=2026-05-26&endDate=2026-05-29&d2=2026-05-29&lodging=CABIN) Condos [](https://www.expedia.com/Hotel-Search?destination=Port+Isabel%2C+Texas%2C+United+States+of+America®ionId=184007&latLong=26.073421%2C-97.208595&adults=2&startDate=2026-05-26&d1=2026-05-26&endDate=2026-05-29&d2=2026-05-29&lodging=CONDO) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Port+Isabel%2C+Texas%2C+United+States+of+America®ionId=184007&latLong=26.073421%2C-97.208595&adults=2&startDate=2026-05-26&d1=2026-05-26&endDate=2026-05-29&d2=2026-05-29&lodging=VACATION_HOME) Apartments [](https://www.expedia.com/Hotel-Search?destination=Port+Isabel%2C+Texas%2C+United+States+of+America®ionId=184007&latLong=26.073421%2C-97.208595&adults=2&startDate=2026-05-26&d1=2026-05-26&endDate=2026-05-29&d2=2026-05-29&lodging=APARTMENT) Cottages [](https://www.expedia.com/Hotel-Search?destination=Port+Isabel%2C+Texas%2C+United+States+of+America®ionId=184007&latLong=26.073421%2C-97.208595&adults=2&startDate=2026-05-26&d1=2026-05-26&endDate=2026-05-29&d2=2026-05-29&lodging=COTTAGE) Villas [](https://www.expedia.com/Hotel-Search?destination=Port+Isabel%2C+Texas%2C+United+States+of+America®ionId=184007&latLong=26.073421%2C-97.208595&adults=2&startDate=2026-05-26&d1=2026-05-26&endDate=2026-05-29&d2=2026-05-29&lodging=VILLA) Houseboats [](https://www.expedia.com/Hotel-Search?destination=Port+Isabel%2C+Texas%2C+United+States+of+America®ionId=184007&latLong=26.073421%2C-97.208595&adults=2&startDate=2026-05-26&d1=2026-05-26&endDate=2026-05-29&d2=2026-05-29&lodging=HOUSE_BOAT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPort-Isabel-Vacation-Rentals.d184007.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPort-Isabel-Vacation-Rentals.d184007.Travel-Guide-VacationRentals) ## Top Port Isabel Hotel Reviews ![Margaritaville Beach Resort South Padre Island ](https://images.trvl-media.com/lodging/1000000/30000/22000/21996/6db563a5_y.jpg) ### Margaritaville Beach Resort South Padre Island 10/10 Excellent "Hotel and room was clean and smelled good. Nice amenities. Staff were pleasant! Did not like the fact that big animals are allowed at the hotel. Other than that, no complaints. " [](https://expedia.com/South-Padre-Island-Hotels-Pearl-South-Padre.h21996.Hotel-Information) ![Isla Grand Beach Resort](https://images.trvl-media.com/lodging/1000000/10000/9100/9005/ea4039fe_y.jpg) ### Isla Grand Beach Resort 10/10 Excellent "The location and proximity to the beach was the best. I stayed in an Ocean View room, just a few doors down from the beach access and it took just a minute to be in the sand. I enjoyed the Adirondack chairs on my front patio where I could sit and watch the ocean at sunrise and sunset. The room itself was small, fine and relatively clean. That close to the beach you're gonna get a few bugs that come in as you open and close doors but no hygiene concerns. Very relaxing. There were a lot of people in the pool area so I avoided that, but the restaurant was decent and the views are spectacular. I'll stay here again" [](https://expedia.com/South-Padre-Island-Hotels-Isla-Grand-Beach-Resort.h9005.Hotel-Information) ![Comfort Inn](https://images.trvl-media.com/lodging/1000000/480000/475400/475371/8cb23c6e_y.jpg) ### Comfort Inn 10/10 Excellent "Room was clean and tidy, bed is really comfortable, great location and ample parking. " [](https://expedia.com/South-Padre-Island-Hotels-Island-Inn-South-Padre-Island-Beach.h475371.Hotel-Information) ![Courtyard by Marriott South Padre Island](https://images.trvl-media.com/lodging/44000000/43520000/43511700/43511682/7ac84e1f_y.jpg) ### Courtyard by Marriott South Padre Island 10/10 Excellent "Great hotel…clean, the room was bigger than my studio apartment in CA! Food at Bar Louie’s was excellent and the pool and ocean bar were relaxing and a great perk. " [](https://expedia.com/South-Padre-Island-Hotels-Courtyard-By-Marriott-South-Padre-Island.h43511682.Hotel-Information) ![Sunchase Inn & Suites](https://images.trvl-media.com/lodging/3000000/2360000/2351100/2351046/2deabedf_y.jpg) ### Sunchase Inn & Suites 10/10 Excellent "Room was very clean and spacious, and affordable with everything made us want to stay for longer however we couldn't" [](https://expedia.com/South-Padre-Island-Hotels-Suites-At-Sunchase.h2351046.Hotel-Information) ![El Delfín Lodge](https://images.trvl-media.com/lodging/77000000/76150000/76149600/76149536/167ea208_y.jpg) ### El Delfín Lodge 10/10 Excellent "Room was clean and comfortable. Staff was kind and courteous " [](https://expedia.com/South-Padre-Island-Hotels-El-Delfin-Lodge.h76149536.Hotel-Information) ![Wanna Wanna Inn](https://images.trvl-media.com/lodging/1000000/920000/911900/911868/0ee44ed9_y.jpg) ### Wanna Wanna Inn 10/10 Excellent "Friendly staff rooms were clean they welcomed my pet with open arms our second stay and def will come back!!! Right on the beach with a bar and restaurant " [](https://expedia.com/South-Padre-Island-Hotels-Wanna-Wanna-Inn.h911868.Hotel-Information) ![Comfort Suites Beachside](https://images.trvl-media.com/lodging/1000000/670000/662000/661940/3f6d3158_y.jpg) ### Comfort Suites Beachside 10/10 Excellent "Great room, great breakfast. Great a/c" [](https://expedia.com/South-Padre-Island-Hotels-Comfort-Suites-South-Padre-Island.h661940.Hotel-Information) ![Hilton Garden Inn South Padre Island Beachfront](https://images.trvl-media.com/lodging/4000000/3510000/3508900/3508863/a7c9c9bc_y.jpg) ### Hilton Garden Inn South Padre Island Beachfront 10/10 Excellent "Clean and quiet room. " [](https://expedia.com/South-Padre-Island-Hotels-Hilton-Garden-Inn-South-Padre-Island-Beachfront.h3508863.Hotel-Information) ## Find out more about Port Isabel **Everything you need to know about Port Isabel vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Port Isabel vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Port Isabel vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Port Isabel vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Port Isabel. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Port Isabel in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $309 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on Port Isabel rentals** At Expedia, we put the best Port Isabel vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Port Isabel rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Port Isabel vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Port Isabel. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com - All accommodation types in Port Isabel ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - 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[Condo Rentals in Port Isabel ](https://expedia.com/Port-Isabel-Condos.d184007-aaCondos.Travel-Guide-Accommodation) - [Vacation Homes in Port Isabel ](https://expedia.com/Port-Isabel-Private-Vacation-Homes.d184007-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Apartments in Port Isabel ](https://expedia.com/Port-Isabel-Apartments.d184007-aaApartments.Travel-Guide-Accommodation) - [Cottages in Port Isabel ](https://expedia.com/Port-Isabel-Cottages.d184007-aaCottages.Travel-Guide-Accommodation) - [Villas in Port Isabel ](https://expedia.com/Port-Isabel-Villas.d184007-aaVillas.Travel-Guide-Accommodation) - [Motels in Port Isabel ](https://expedia.com/Port-Isabel-Motels.d184007-aaMotels.Travel-Guide-Accommodation) - [Cabin Rentals in Port Isabel ](https://expedia.com/Port-Isabel-Cabins.d184007-aaCabins.Travel-Guide-Accommodation) - [Aparthotels in Port Isabel ](https://expedia.com/Port-Isabel-Apart-Hotels.d184007-aaApartHotels.Travel-Guide-Accommodation) - [Resorts in Port Isabel ](https://expedia.com/Port-Isabel-Resorts.d184007-aaResorts.Travel-Guide-Accommodation) - [Lodges in Port Isabel ](https://expedia.com/Port-Isabel-Lodges.d184007-aaLodges.Travel-Guide-Accommodation) - [Houseboats in Port Isabel ](https://expedia.com/Port-Isabel-Houseboats.d184007-aaHouseboats.Travel-Guide-Accommodation) - [Condo Resorts in Port Isabel ](https://expedia.com/Port-Isabel-Condominium-Resort.d184007-aaCondominiumResort.Travel-Guide-Accommodation) - [RV Parks in Port Isabel ](https://expedia.com/Port-Isabel-RV-Parks.d184007-aaRVParks.Travel-Guide-Accommodation) - [Town Houses in Port Isabel ](https://expedia.com/Port-Isabel-Town-Houses.d184007-aaTownHouses.Travel-Guide-Accommodation) ## Frequently asked questions ### Can I find vacation rentals in Port Isabel? ### What are some of the best vacation home rentals that Port Isabel has to offer? ### How many vacation rentals are there in Port Isabel? ### What can I see and do in Port Isabel? ### What are vacation rentals like in Port Isabel? ### Expedia's Latest Trends Hotels - [Hotel Rooms in San Marcos](https://expedia.com/San-Marcos-Hotels.d6647.Travel-Guide-Hotels) - 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