Santa Isabel Vacation Rentals

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Our top choices for Santa Isabel vacation rentals

Casa Palma Serena - Garden Retreat • Tropical Stay

Casa Palma Serena - Garden Retreat • Tropical Stay
Santa Isabel
10.0 out of 10, Exceptional, (2 reviews)
"Our host was very accommodating! The home was beautiful "
United States
Sally R.
$293 nightly
The price is $311
Jun 9 - Jun 10
Total with taxes and fees
Casa Palma Serena - Garden Retreat • Tropical Stay

Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2

Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2
Santa Isabel
10.0 out of 10, Exceptional, (2 reviews)
"We enjoyed our stay immensely. The bed was very comfortable. We loved the outdoor spaces. The parking was a little hard to figure out at first. We loved sitting by the water’s edge with morning coffee and evening glass of wine. "
United States
Penny O.
$506 nightly
The price is $537
May 25 - May 26
Total with taxes and fees
Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Santa Isabel
8.8 out of 10, Excellent, (48 reviews)
"Very nice,on the ocean,steps to beach need repair"
United States
James
$339 nightly
The price is $360
May 28 - May 29
Total with taxes and fees
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Coming and enjoy panoramic views to mountains and sea in Santa Isabel

Coming and enjoy panoramic views to mountains and sea in Santa Isabel
Santa Isabel
10.0 out of 10, Exceptional, (1 review)
"This is a unique property with beautiful views. The hosts were incredibly helpful and responsive!"
United States
Annie H.
$316 nightly
The price is $336
Jun 4 - Jun 5
Total with taxes and fees
Coming and enjoy panoramic views to mountains and sea in Santa Isabel

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
Santa Isabel
10.0 out of 10, Exceptional, (4 reviews)
"Great host communication, central location, lovely home. "
United States
Scott P.
$521 nightly
The price is $554
Jun 7 - Jun 8
Total with taxes and fees
Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

La Gozadera Park

La Gozadera Park
1.0 star property
Salinas
10.0 out of 10, Exceptional, (2 reviews)
$120 nightly
The price is $131
May 25 - May 26
Total with taxes and fees
La Gozadera Park

The Place at the Sea

The Place at the Sea
3.0 star property
Ponce
9.4 out of 10, Exceptional, (340 reviews)
"Beautiful place"
United States
Angela
$53 nightly
The price is $58
May 28 - May 29
Total with taxes and fees
The Place at the Sea

Grandpa's lake house lake private access mountain view museum 1950's experience

Grandpa's lake house lake private access mountain view museum 1950's experience
Cidra
9.4 out of 10, Exceptional, (6 reviews)
"We had a great peaceful visit!"
United States
Kelly N.
$110 nightly
The price is $117
May 25 - May 26
Total with taxes and fees
Grandpa's lake house lake private access mountain view museum 1950's experience

A cozy place to stay walking distance from the beach and Restaurants.

A cozy place to stay walking distance from the beach and Restaurants.
Salinas
9.4 out of 10, Exceptional, (26 reviews)
"Complete kitchen, fairly quiet area, near great restaurants "
United States
John W.
$133 nightly
The price is $141
May 25 - May 26
Total with taxes and fees
A cozy place to stay walking distance from the beach and Restaurants.

Tiny Cozy Mountain Cabin Peaceful Retreat in Cayey

Tiny Cozy Mountain Cabin Peaceful Retreat in Cayey
Cayey
8.0 out of 10, Very Good, (1 review)
$141 nightly
The price is $157
Jun 1 - Jun 2
Total with taxes and fees
Tiny Cozy Mountain Cabin Peaceful Retreat in Cayey

HW Tiny Home Cidra

HW Tiny Home Cidra
Cidra
10.0 out of 10, Exceptional, (2 reviews)
"Beautiful area, great AC, clean hot tub, lovely acces to lake with paddleboat!"
United States
Elizabeth C.
$177 nightly
The price is $188
May 26 - May 27
Total with taxes and fees
HW Tiny Home Cidra

Oasis Salinas

Oasis Salinas
Salinas
7.8 out of 10, Good, (13 reviews)
"Excellent place to stay near everything in town "
United States
Mayra
$130 nightly
The price is $138
May 25 - May 26
Total with taxes and fees
Oasis Salinas

Aibonito Hotel 205

Aibonito Hotel 205
3.0 star property
Aibonito
7.6 out of 10, Good, (22 reviews)
"We had a wonderful stay. No complaints. Thorough directions given on how to check in and out. Communication was available if needed. We have family nearby and we will definitely book again. "
United States
Annette
$68 nightly
The price is $73
Jun 5 - Jun 6
Total with taxes and fees
Aibonito Hotel 205

Points Apartments

Points Apartments
Guayama
9.4 out of 10, Exceptional, (3 reviews)
"Great property great people"
United States
Julian
$197 nightly
The price is $209
May 25 - May 26
Total with taxes and fees
Points Apartments

Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR

Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR
Coamo
7.0 out of 10, Good, (2 reviews)
"Spotless cozy , ice cold air"
United States
Alberto
$133 nightly
The price is $141
May 25 - May 26
Total with taxes and fees
Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR

Casita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony

Casita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony
Barranquitas
10.0 out of 10, Exceptional, (3 reviews)
"great stay super clean and comfy"
United States
frankie q.
$160 nightly
The price is $170
May 25 - May 26
Total with taxes and fees
Casita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony

Cozy studio with private Pool and Bar modern amentities perfect for relaxation.

Cozy studio with private Pool and Bar modern amentities perfect for relaxation.
Cidra
8.4 out of 10, Very Good, (6 reviews)
"We have a wonderful time! The pool and bar were perfect!"
United States
Anna D.
$240 nightly
The price is $254
May 26 - May 27
Total with taxes and fees
Cozy studio with private Pool and Bar modern amentities perfect for relaxation.

House Salinas (WIFI) - The best part of your getaway

House Salinas (WIFI) - The best part of your getaway
Salinas
9.8 out of 10, Exceptional, (24 reviews)
"Really good place to stay with family and friends. The location is perfect, is close to everything. The house is super cozy. Alfredo is awesome! "
United States
Vallerie
$228 nightly
The price is $242
May 26 - May 27
Total with taxes and fees
House Salinas (WIFI) - The best part of your getaway

LA CASITA DEL LAGO

LA CASITA DEL LAGO
Cidra
10.0 out of 10, Exceptional, (3 reviews)
"The location was amazing "
United States
Maria
$187 nightly
The price is $199
May 25 - May 26
Total with taxes and fees
LA CASITA DEL LAGO

RED LOFT VIBE WALKING DISTANCE TO THE CITY

RED LOFT VIBE WALKING DISTANCE TO THE CITY
Guayama
9.6 out of 10, Exceptional, (5 reviews)
"The best place to spend your days if you visit the city of Guayama, easy access to all the sites of interest in the area."
United States
Hector
$112 nightly
The price is $118
May 25 - May 26
Total with taxes and fees
RED LOFT VIBE WALKING DISTANCE TO THE CITY
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Isabel Hotel Reviews

Find out more about Santa Isabel

Everything you need to know about Santa Isabel vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Isabel vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Isabel vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Isabel vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Isabel. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Isabel in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $58 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Isabel rentals

At Expedia, we put the best Santa Isabel vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Isabel rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Isabel vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Isabel. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Santa Isabel?

Yes, there are vacation rentals close to the most popular attractions in Santa Isabel, or you can choose a secluded option if you're looking for relaxation. Santa Isabel is known for its shopping and restaurants. Make sure you have time to check out the beaches while you're in the area.

What's the top vacation rental that Santa Isabel has to offer?

3BR Puerto Rico Villa w Pool | Aqua Bella 1: This highly rated vacation home rental in Santa Isabel is located by the ocean and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. Our travelers also rate Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep as a favorite home for rent in Santa Isabel.

How many vacation rentals will I find in Santa Isabel?

Expedia has 7 vacation rentals for your stay in Santa Isabel.

What can I see and do in Santa Isabel?

Explore the area and family-friendly sights such as Museo de la Musica Puertorriquena, or get out into nature at a spot like Coamo Springs. Carribbean Cinemas Santa Isabel and Marina de Salinas are a couple of places you'll find in the larger area.

What are vacation rentals like in Santa Isabel?

Vacation rentals are privately owned properties you can reserve for a couple days or more in Santa Isabel. Vacation rentals offer extras like WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a popular option for a family trip.