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Santa Isabel Vacation Rentals

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Check prices for these dates

In two weeks
Oct 30 - Nov 1
In two months
Dec 11 - Dec 13
In three months
Jan 8 - Jan 10
In four months
Feb 5 - Feb 7

Our top choices for Santa Isabel vacation rentals

A beach with clear turquoise water, a sandy shore, and a rocky hill in the background.

1. Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2

Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2
Santa Isabel
10.0 out of 10, Exceptional, (3 reviews)
"We enjoyed our stay immensely. The bed was very comfortable. We loved the outdoor spaces. The parking was a little hard to figure out at first. We loved sitting by the water’s edge with morning coffee and evening glass of wine. "
United States
Penny O.
$496 nightly
The price is $527
Oct 18 - Oct 19
Total with taxes and fees
Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2
A view through a window with a view of the sea and a small island.

2. Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Santa Isabel
8.8 out of 10, Excellent, (50 reviews)
"Host was very responsive to our texts"
United States
Arnie S.
$339 nightly
The price is $360
Oct 19 - Oct 20
Total with taxes and fees
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
A rooftop terrace with a red pool, string lights, and a hanging chair.

3. Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
Santa Isabel
10.0 out of 10, Exceptional, (5 reviews)
"Great host communication, central location, lovely home. "
United States
Scott P.
$439 nightly
The price is $467
Oct 18 - Oct 19
Total with taxes and fees
Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
A modern house with a pool, wooden deck, and outdoor seating area.

4. Coming and enjoy panoramic views to mountains and sea in Santa Isabel

Coming and enjoy panoramic views to mountains and sea in Santa Isabel
Santa Isabel
10.0 out of 10, Exceptional, (1 review)
"This is a unique property with beautiful views. The hosts were incredibly helpful and responsive!"
United States
Annie H.
$316 nightly
The price is $336
Oct 26 - Oct 27
Total with taxes and fees
Coming and enjoy panoramic views to mountains and sea in Santa Isabel
An outdoor seating area with wicker furniture, a table with a bottle, and a view of the sea.

5. The Place at the Sea

The Place at the Sea
3.0 star property
Ponce
9.4 out of 10, Exceptional, (472 reviews)
"The stay was amazing."
United States
Osvaldo
$52 nightly
The price is $57
Oct 26 - Oct 27
Total with taxes and fees
The Place at the Sea
A compact RV kitchen with wooden cabinets, a built-in TV, a small dining area, and a sink.

6. La Gozadera Park

La Gozadera Park
1.0 star property
Salinas
10.0 out of 10, Exceptional, (7 reviews)
"It was easy to find and the host was very friendly, humble and professional"
United States
Ondina
$105 nightly
The price is $115
Oct 25 - Oct 26
Total with taxes and fees
La Gozadera Park
A cozy living room with a wooden ceiling, a sofa, a wicker chair, and a flag on the door.

7. A cozy place to stay walking distance from the beach and Restaurants.

A cozy place to stay walking distance from the beach and Restaurants.
Salinas
9.4 out of 10, Exceptional, (27 reviews)
"Complete kitchen, fairly quiet area, near great restaurants "
United States
John W.
$133 nightly
The price is $141
Oct 19 - Oct 20
Total with taxes and fees
A cozy place to stay walking distance from the beach and Restaurants.
A beach with boats docked in calm waters, a clear sky, and a sandy shore.

8. House Salinas (WIFI) - The best part of your getaway

House Salinas (WIFI) - The best part of your getaway
Salinas
9.8 out of 10, Exceptional, (24 reviews)
"Nice cozy home near downtiwn, Salinas PR"
United States
Kenneth C.
$243 nightly
The price is $258
Nov 2 - Nov 3
Total with taxes and fees
House Salinas (WIFI) - The best part of your getaway
An outdoor patio area with wicker furniture and a stone floor, surrounded by lush greenery and trees.

9. Oasis Salinas

Oasis Salinas
Salinas
8.0 out of 10, Very good, (14 reviews)
"Excellent place to stay near everything in town "
United States
Mayra
$130 nightly
The price is $138
Oct 19 - Oct 20
Total with taxes and fees
Oasis Salinas
Interior

10. Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR

Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR
Coamo
7.0 out of 10, Good, (2 reviews)
"Spotless cozy , ice cold air"
United States
Alberto
$140 nightly
The price is $148
Oct 19 - Oct 20
Total with taxes and fees
Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR
A modern kitchen with black cabinets, a stainless steel countertop, a built-in microwave, a coffee maker, and a potted plant on the counter.

11. Gladiolas 2101

Gladiolas 2101
3.0 star property
Ponce Centro
8.6 out of 10, Excellent, (10 reviews)
"Great location. Comfortable room with all amenities needed. "
United States
Geovanna
$160 nightly
The price is $171
Oct 19 - Oct 20
Total with taxes and fees
Gladiolas 2101
An aerial view of a small island with clear turquoise waters, a sandy beach, and a few structures.

12. Homey Escape with Patio Access and FREE Laundry

Homey Escape with Patio Access and FREE Laundry
Ponce
9.0 out of 10, Wonderful, (19 reviews)
"The place was very nice and in a quiet neighborhood. Exactly what I was looking for a couple of days. I would recommend it to friends and family. "
United States
Louis A.
$152 nightly
The price is $162
Oct 18 - Oct 19
Total with taxes and fees
Homey Escape with Patio Access and FREE Laundry
Beach

13. Private Jacuzzi Retreat with Mountain Views, Generator and Parking,

Private Jacuzzi Retreat with Mountain Views, Generator and Parking,
Ponce
9.2 out of 10, Wonderful, (10 reviews)
"The service was great and Jose house keeping was awesome."
United States
Anonymous traveler
$235 nightly
The price is $249
Oct 18 - Oct 19
Total with taxes and fees
Private Jacuzzi Retreat with Mountain Views, Generator and Parking,
A wooden deck with a welcome mat and potted plants.

14. Nostra Casa Vagón

Nostra Casa Vagón
Coamo
10.0 out of 10, Exceptional, (1 review)
"Everything was very clean and organized I got confused with the address and the owner communicated with me and directed me to the exact address when I go to Puerto Rico again I will contact them again to stay at the same place "
United States
Carlos Reyes
$140 nightly
The price is $148
Oct 18 - Oct 19
Total with taxes and fees
Nostra Casa Vagón
An aerial view of a small island with clear turquoise waters, a sandy beach, and a few structures.

15. Private Patio Retreat with Zen Vibe and Laundry

Private Patio Retreat with Zen Vibe and Laundry
Ponce
9.4 out of 10, Exceptional, (16 reviews)
"Was great quiet, clean and very safe, we felt confortable and the neighbors were very friendly "
United States
Magda R.
$137 nightly
The price is $145
Oct 18 - Oct 19
Total with taxes and fees
Private Patio Retreat with Zen Vibe and Laundry
An aerial view of a small island with clear turquoise waters, a sandy beach, and a few structures.

16. Private Jacuzzi Oasis with Mountain Views. FREE Parking and Laundry

Private Jacuzzi Oasis with Mountain Views. FREE Parking and Laundry
Ponce
7.6 out of 10, Good, (7 reviews)
"The home is lovely! Has good WiFi access, the kitchen is modern & functional! Getting here from the airport was literally a breeze after picking up our rental from the airport! Check-in took longer than expected b/c the host provided us the wrong code, he took a while to respond but eventually we got in! "
United States
Ray G.
$235 nightly
The price is $249
Oct 18 - Oct 19
Total with taxes and fees
Private Jacuzzi Oasis with Mountain Views. FREE Parking and Laundry
A wooden dresser with a potted plant on top, a mirror above it, and a decorative piece on the dresser.

17. Trinitarias Guest's House's pool/bar/karaoke/wifi

Trinitarias Guest's House's pool/bar/karaoke/wifi
Salinas
9.0 out of 10, Wonderful, (4 reviews)
"Felt like home beautiful super clean quiet I will definitely be back to this home in our vacations Host is amazing Thank You for sharing this beautiful house with my family "
United States
julio
$175 nightly
The price is $186
Oct 20 - Oct 21
Total with taxes and fees
Trinitarias Guest's House's pool/bar/karaoke/wifi
Beach

18. Compact Haven with Private Entrance and FREE Parking and Laundry

Compact Haven with Private Entrance and FREE Parking and Laundry
Ponce
9.2 out of 10, Wonderful, (17 reviews)
"Apartment was very good, location was close to everything. Off street parking great."
United States
Anonymous traveler
$160 nightly
The price is $169
Oct 18 - Oct 19
Total with taxes and fees
Compact Haven with Private Entrance and FREE Parking and Laundry
A dining area with a table and chairs, a kitchen with appliances, and a balcony with a view of a building.

19. Gladioli 1206 - That's all Puerto Rico

Gladioli 1206 - That's all Puerto Rico
Ponce Centro
6.6 out of 10, (4 reviews)
"Convenient and just what I needed. A place close to everything and at a reasonable price. The balcony style doors are awesome as well, Wish it retained more of its old features and charm."
United States
Jorje R.
$182 nightly
The price is $193
Oct 19 - Oct 20
Total with taxes and fees
Gladioli 1206 - That's all Puerto Rico
An aerial view of a small island with clear turquoise waters, a sandy beach, and a few structures.

20. Expansive Paradise with Private Jacuzzi and Tropical Patio

Expansive Paradise with Private Jacuzzi and Tropical Patio
Ponce
8.8 out of 10, Excellent, (3 reviews)
"Hella chill"
United States
Sammy S.
$345 nightly
The price is $366
Oct 18 - Oct 19
Total with taxes and fees
Expansive Paradise with Private Jacuzzi and Tropical Patio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Isabel Hotel Reviews

The Place at the Sea

The Place at the Sea

8/10 Good
"Quirky but charming and comfortable room, with a separate hallway and kitchen area. The entrance is at the top of an exterior staircase, which made unlocking the key box and door a little awkward while balancing a bag. We felt perfectly safe walking around and found a neighborhood bar with the best fish tacos and great beer. A nice stay and great value."
Elan 1-night trip
Posted 6 hours ago
The Place at the Sea

Find out more about Santa Isabel

Everything you need to know about Santa Isabel vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Isabel vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Isabel vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Isabel vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Isabel. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Isabel in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $57 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Isabel rentals

At Expedia, we put the best Santa Isabel vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Isabel rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Isabel vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Isabel. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in Santa Isabel?

Yes, there are vacation rentals close to the most popular attractions in Santa Isabel, or you can choose a secluded option if you're looking for relaxation. Santa Isabel is known for its shopping and restaurants. Make sure you have time to check out the beaches while you're in the area.

What's the top vacation rental that Santa Isabel has to offer?

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep: This highly rated vacation home rental in Santa Isabel is located on the beach and has a balcony, a selection of games, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. Other favorite homes for rent in Santa Isabel are 3BR Puerto Rico Villa w Pool | Aqua Bella 1 and Modern Cozy Home in Puerto Rican Paradise.

How many vacation rentals will I find in Santa Isabel?

Expedia has 7 vacation rentals for your stay in Santa Isabel.

What can I see and do in Santa Isabel?

Explore the area and family-friendly sights such as Museo de la Musica Puertorriquena, or get out into nature at a spot like Coamo Springs. Carribbean Cinemas Santa Isabel and Marina de Salinas are a couple of places you'll find in the larger area.

What are vacation rentals like in Santa Isabel?

Vacation rentals are privately owned properties you can reserve for a couple days or more in Santa Isabel. Vacation rentals offer extras like WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a popular option for a family trip.