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Find hotels in Southeastern Indiana from $68

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Our top choices for Southeastern Indiana hotels

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3875)
"Beautiful room and great hospitality. "
United States
Chase
$133 nightly
The price is $157
Dec 20 - Dec 21
Total with taxes and fees
Galt House Hotel Trademark Collection by Wyndham
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1002)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
$143 nightly
The price is $169
Jan 1 - Jan 2, 2026
Total with taxes and fees
21c Museum Hotel Louisville
Deluxe Room, 1 King Bed | Blackout drapes, iron/ironing board, free WiFi, bed sheets
Hometowne Inn & Suites

Hometowne Inn & Suites

Hometowne Inn & Suites
3.0 star property
Scottsburg
9.0 out of 10, Wonderful, (514)
"Great room great price very clean"
United States
tim
$68 nightly
The price is $76
Dec 16 - Dec 17
Total with taxes and fees
Hometowne Inn & Suites
Property amenity
Holiday Inn Express & Suites Scottsburg by IHG

Holiday Inn Express & Suites Scottsburg by IHG

Holiday Inn Express & Suites Scottsburg by IHG
2.5 star property
Scottsburg
8.8 out of 10, Excellent, (669)
"Clean hotel "
United States
Matthew
$148 nightly
The price is $166
Jan 2 - Jan 3, 2026
Total with taxes and fees
Holiday Inn Express & Suites Scottsburg by IHG
Property entrance
The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (647)
"Have stayed here once before. Accommodations are wonderful and the sit down breakfast is lovely. Highly recommend this beautiful property."
United States
Kathy
$90 nightly
The price is $102
Dec 17 - Dec 18
Total with taxes and fees
The Pepin Mansion Historic B&B
Lobby
The Grady

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1002)
"Room was great, Bed super comfy, staff was excellent, restaurant was awesome! Highly recommend!"
United States
Andrew
$161 nightly
The price is $189
Dec 22 - Dec 23
Total with taxes and fees
The Grady
3 bars/lounges, cocktail bar, lobby lounge
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1735)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
$167 nightly
The price is $197
Jan 1 - Jan 2, 2026
Total with taxes and fees
Omni Louisville Hotel
Reception
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1112)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
$111 nightly
The price is $131
Dec 28 - Dec 29
Total with taxes and fees
Embassy Suites Louisville Downtown
Lobby
Hyatt Regency Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1002)
"Enjoyed our stay "
United States
Jedediah
$116 nightly
The price is $136
Dec 25 - Dec 26
Total with taxes and fees
Hyatt Regency Louisville
Premium bedding, desk, laptop workspace, iron/ironing board
Comfort Inn & Suites Clarksville - Louisville North

Comfort Inn & Suites Clarksville - Louisville North

Comfort Inn & Suites Clarksville - Louisville North
2.5 star property
Clarksville
9.0 out of 10, Wonderful, (1001)
"Great location"
United States
Ramakrishna
$92 nightly
The price is $104
Dec 22 - Dec 23
Total with taxes and fees
Comfort Inn & Suites Clarksville - Louisville North
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1005)
"The room was wonderful and the staff exceptional."
United States
Daniel
$100 nightly
The price is $118
Jan 9 - Jan 10, 2026
Total with taxes and fees
Homewood Suites by Hilton Louisville Downtown, KY
Lobby
The Brown Hotel

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1154)
"I loved everything about this place"
United States
Steven
$168 nightly
The price is $198
Dec 16 - Dec 17
Total with taxes and fees
The Brown Hotel
Standard Room | Desk, laptop workspace, free WiFi, bed sheets
Fairway Inn Florence

Fairway Inn Florence

Fairway Inn Florence
2.0 star property
Florence
8.4 out of 10, Very Good, (52)
"Convenient to where we needed to go. "
United States
Walter
$75 nightly
The price is $84
Dec 16 - Dec 17
Total with taxes and fees
Fairway Inn Florence
Exterior
Holiday Inn Express Corydon by IHG

Holiday Inn Express Corydon by IHG

Holiday Inn Express Corydon by IHG
2.5 star property
Corydon
8.6 out of 10, Excellent, (361)
"Very clean and great staff!"
United States
Donna
$87 nightly
The price is $97
Dec 21 - Dec 22
Total with taxes and fees
Holiday Inn Express Corydon by IHG
Snack bar
Hampton Inn Louisville-North/Clarksville

Hampton Inn Louisville-North/Clarksville

Hampton Inn Louisville-North/Clarksville
2.5 star property
Clarksville
8.8 out of 10, Excellent, (668)
"Great area to stay."
United States
Andy
$86 nightly
The price is $98
Dec 22 - Dec 23
Total with taxes and fees
Hampton Inn Louisville-North/Clarksville
Property amenity
Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (509)
"Great rooms "
United States
Ayden
$97 nightly
The price is $114
Jan 1 - Jan 2, 2026
Total with taxes and fees
Towneplace Suites By Marriott Louisville Downtown
Lobby sitting area
Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North
2.5 star property
Sellersburg
8.4 out of 10, Very Good, (1001)
"Clean room, helpful staff, good breakfast "
United States
Jessica
$72 nightly
The price is $82
Dec 18 - Dec 19
Total with taxes and fees
Ramada by Wyndham Sellersburg/Louisville North
Breakfast and dinner served
Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North
3.0 star property
Jeffersonville
9.6 out of 10, Exceptional, (406)
"Checking process was smooth, room was clean all within my expectations. "
United States
Angel
$103 nightly
The price is $117
Dec 22 - Dec 23
Total with taxes and fees
Hilton Garden Inn Jeffersonville Louisville North
3 restaurants, breakfast, lunch, dinner served; American cuisine
Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination
3.5 star property
Elizabeth
8.2 out of 10, Very Good, (1002)
"The room was very clean, the staff was very friendly and helpful."
United States
Judy
$105 nightly
The price is $117
Jan 14 - Jan 15, 2026
Total with taxes and fees
Caesars Southern Indiana - A Caesars Rewards Destination
Exterior
Comfort Inn Madison near Clifty Falls

Comfort Inn Madison near Clifty Falls

Comfort Inn Madison near Clifty Falls
2.5 star property
Madison
8.8 out of 10, Excellent, (664)
"Great stay, clean, and comfy bed!"
United States
cheryl
$93 nightly
The price is $107
Dec 28 - Dec 29
Total with taxes and fees
Comfort Inn Madison near Clifty Falls
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Vacation Rentals in Southeastern Indiana

Cottage
House (3 Bedrooms) | Interior
Home w/ Fenced Backyard, 6 Mi to Dtwn Louisville!

Home w/ Fenced Backyard, 6 Mi to Dtwn Louisville!

Home w/ Fenced Backyard, 6 Mi to Dtwn Louisville!
3.0 star property
New Albany
10.0 out of 10, Exceptional, (1)
"Amy was wonderful and went above and beyond to make sure we had a great stay. She even left pancakes w/syrup for breakfast and pasta w/sauce in case we didn’t have time to go to the store! It’s the small things that really stick out such as leaving a bowl of snacks, a few beers in the fridge, a bottle of wine, fully stocked medicine cabinet in case you forgot something. She even put food and water out for the dog along with toys and a blanket! We loved being there and it was such a beautiful...
Home w/ Fenced Backyard, 6 Mi to Dtwn Louisville!
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Stay near popular Southeastern Indiana attractions

Panorama Ohio River waterway riverboats and bridges leading to heart of downtown Louisville KY

KFC Yum Center

4.3/5 (799 reviews)
Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.
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Exploration of Louisville Slugger Museum in Downtown Louisville, Kentucky on a Sunny Day

Louisville Slugger Museum

4.5/5 (1,200 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
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Learn more about Southeastern Indiana

Live music, a scenic riverfront, and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards—discover it all in Southeastern Indiana.

See all hotels in Southeastern Indiana
Bathe in the forest...find this on the roof of the outdoor shower house down the hill from the guest house.
Photo by Serendipity Trip
Open Photo by Serendipity Trip

Top Southeastern Indiana Hotel Reviews

Best Western Green Tree Inn

Best Western Green Tree Inn

10/10 Excellent
"Eggs, Proteins, Carbs, coffees, cereal, bread, muffin, juices, tea, milk..."
Lynda 4-night trip
Posted 3 days ago
Best Western Green Tree Inn

More cheap stays in Southeastern Indiana

Best Way Inn Madison

Best Way Inn Madison

700 Clifty Drive Madison IN
$69 nightly
The price is $79 total per night from Jan 1 to Jan 2
$79 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
6.8/10 (522 reviews)

Hotels in Southeastern Indiana with star-rating