$126 Cheap Flights from Charleston (CHS) to Buffalo (BUF)

View $126 flight on Wed, Jul 1, 2026Opens in a new window

Popular airlines from Charleston Intl. Airport (CHS) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Charleston to Buffalo (CHS-BUF)

Prices were available within the past 7 days and start at $126 for one-way flights and $251 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Thu, Jun 25 - Mon, Jun 29
CHS
Charleston
BUF
Buffalo
$251 Roundtrip, found 5 hours ago
$251
Roundtrip
found 5 hours ago
Select JetBlue Airways flight, departing Thu, Jun 25 from Charleston to Buffalo, returning Mon, Jun 29, priced at $251 found 5 hours ago
United
Tue, May 5 - Wed, May 6
CHS
Charleston
BUF
Buffalo
$252 Roundtrip, found 1 day ago
$252
Roundtrip
found 1 day ago
Select United flight, departing Tue, May 5 from Charleston to Buffalo, returning Wed, May 6, priced at $252 found 1 day ago
Delta
Wed, Jun 3 - Mon, Jun 8
CHS
Charleston
BUF
Buffalo
$254 Roundtrip, found 5 hours ago
$254
Roundtrip
found 5 hours ago
Select Delta flight, departing Wed, Jun 3 from Charleston to Buffalo, returning Mon, Jun 8, priced at $254 found 5 hours ago
Southwest Airlines
Tue, Jun 2 - Sun, Jun 7
CHS
Charleston
BUF
Buffalo
$257 Roundtrip, just found
$257
Roundtrip
just found
Select Southwest Airlines flight, departing Tue, Jun 2 from Charleston to Buffalo, returning Sun, Jun 7, priced at $257 just found
Delta
Wed, Jul 29 - Mon, Aug 3
CHS
Charleston
BUF
Buffalo
$257 Roundtrip, found 2 hours ago
$257
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Jul 29 from Charleston to Buffalo, returning Mon, Aug 3, priced at $257 found 2 hours ago
American Airlines
Wed, Aug 5 - Tue, Aug 11
CHS
Charleston
BUF
Buffalo
$257 Roundtrip, found 12 hours ago
$257
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Wed, Aug 5 from Charleston to Buffalo, returning Tue, Aug 11, priced at $257 found 12 hours ago
United
Sat, Apr 25 - Sun, Apr 26
CHS
Charleston
BUF
Buffalo
$258 Roundtrip, found 1 day ago
$258
Roundtrip
found 1 day ago
Select United flight, departing Sat, Apr 25 from Charleston to Buffalo, returning Sun, Apr 26, priced at $258 found 1 day ago
JetBlue Airways
Thu, Jun 25 - Mon, Jun 29
CHS
Charleston
BUF
Buffalo
$260 Roundtrip, found 5 hours ago
$260
Roundtrip
found 5 hours ago
Select JetBlue Airways flight, departing Thu, Jun 25 from Charleston to Buffalo, returning Mon, Jun 29, priced at $260 found 5 hours ago
United
Wed, Jun 3 - Mon, Jun 8
CHS
Charleston
BUF
Buffalo
$262 Roundtrip, found 5 hours ago
$262
Roundtrip
found 5 hours ago
Select United flight, departing Wed, Jun 3 from Charleston to Buffalo, returning Mon, Jun 8, priced at $262 found 5 hours ago
American Airlines
Wed, Apr 29 - Sat, May 2
CHS
Charleston
BUF
Buffalo
$264 Roundtrip, found 1 day ago
$264
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Apr 29 from Charleston to Buffalo, returning Sat, May 2, priced at $264 found 1 day ago

Alternative airports near Buffalo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Buffalo Niagara Intl. BUF. Cheapest and Closest option available. Average driving time to city center is 16 minutes. Flights from $309
BUF
Buffalo Niagara Intl.
CheapestClosest
Average driving time to city center16 min
Flights from $309

Find the cheapest month to fly from Charleston (CHS) to Buffalo (BUF)

October is typically the cheapest month to fly

From $160 - $434 per traveler.

Frequently asked questions

How much does a flight from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from $126 and cheap return flights from $251 Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) with Expedia. One-way flights generally range between $106 and $592, and roundtrip flights usually range from $263 to $952. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
January is the cheapest month to fly from Charleston, SC (CHS) to Buffalo, NY (BUF), with average return fares around $259. This is about 20% lower than the average price throughout the year, as travel demand typically decreases after the holiday season. Other affordable months to fly from Charleston to Buffalo include August and September.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter CHS to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
JetBlue Airways is one of the cheapest airlines offering connecting flights from Charleston Intl. (CHS) to Buffalo Niagara Intl. (BUF), starting from around $177. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
When flying from Charleston (CHS) to Buffalo (BUF), January and September are your best bets. With average return flight prices around $259, these months offer both affordability and good travel conditions. January is quieter post-holidays, while September provides a lovely early fall atmosphere.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Charleston, SC (CHS) to Buffalo, NY (BUF) typically leaves at around 5:00 AM, operated by American Airlines. This seasonal service is available in December, allowing you to get an early start on your trip to Buffalo. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from Charleston Intl. (CHS) to Buffalo Niagara Intl. (BUF) are in the early morning, from 6am to 9am. About 35% of passengers prefer this time window. Major carriers like American Airlines, Delta Airlines, and Southwest Airlines offer flights during this window. This timing is great for travelers wanting to make the most of their day in Buffalo.
How long does it take to fly from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Flying from CHS to BUF with a connection usually takes about 4 hours, traveling roughly 698 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
First class seats are offered on the CHS to BUF route. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from Charleston Intl. (CHS)?
If you're planning to travel to Buffalo from Charleston Intl. (CHS), you can fly into Buffalo Niagara Intl. (BUF) Some flights may connect through major hubs like Liberty Intl. (EWR), Washington Dulles Intl. (IAD), O'Hare Intl. (ORD) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) Buffalo Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Charleston, SC (CHS-Charleston Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Charleston Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, JetBlue Airways, Southwest Airlines, United
Roundtrip price
$250
Distance
697 mi

Book with confidence

Charleston to Buffalo Flights

The cheapest times to fly from Charleston to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charleston to Buffalo are during the month of June. You can find some of the cheapest flights from Charleston to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charleston to Buffalo

Sunday is one of the best days to book for cheap flights from Charleston to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charleston to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charleston to Buffalo in 2026. You can also book with separate airlines for your outbound and return journeys, from $126 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charleston to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charleston to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Charleston to Buffalo Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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