$473 Cheap Flights from Southampton (SOU) to San Francisco (SFO)

View $473 flight on Mon, Jan 12, 2026Opens in a new window

Popular airlines from Southampton (SOU) to San Francisco Intl. Airport (SFO)

Cheap Flights from Southampton to San Francisco (SOU-SFO)

Prices were available within the past 7 days and start at $473 for one-way flights and $799 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aer Lingus
Sat, Nov 1 - Wed, Nov 5
SOU
Southampton
SFO
San Francisco
$799 Roundtrip, found 2 hours ago
$799
Roundtrip
found 2 hours ago
Select Aer Lingus flight, departing Sat, Nov 1 from Southampton to San Francisco, returning Wed, Nov 5, priced at $799 found 2 hours ago
Virgin Atlantic
Wed, Nov 26 - Wed, Dec 3
SOU
Southampton
SFO
San Francisco
$847 Roundtrip, found 3 days ago
$847
Roundtrip
found 3 days ago
Select Virgin Atlantic flight, departing Wed, Nov 26 from Southampton to San Francisco, returning Wed, Dec 3, priced at $847 found 3 days ago
Virgin Atlantic
Wed, Nov 26 - Wed, Dec 3
SOU
Southampton
SFO
San Francisco
$891 Roundtrip, found 3 days ago
$891
Roundtrip
found 3 days ago
Select Virgin Atlantic flight, departing Wed, Nov 26 from Southampton to San Francisco, returning Wed, Dec 3, priced at $891 found 3 days ago
Virgin Atlantic
Wed, Nov 26 - Wed, Dec 3
SOU
Southampton
SFO
San Francisco
$897 Roundtrip, found 3 days ago
$897
Roundtrip
found 3 days ago
Select Virgin Atlantic flight, departing Wed, Nov 26 from Southampton to San Francisco, returning Wed, Dec 3, priced at $897 found 3 days ago
Aer Lingus
Sun, Apr 5 - Sat, Apr 18
SOU
Southampton
SFO
San Francisco
$938 Roundtrip, found 11 hours ago
$938
Roundtrip
found 11 hours ago
Select Aer Lingus flight, departing Sun, Apr 5 from Southampton to San Francisco, returning Sat, Apr 18, priced at $938 found 11 hours ago
Virgin Atlantic
Wed, Nov 26 - Wed, Dec 3
SOU
Southampton
SFO
San Francisco
$948 Roundtrip, found 3 days ago
$948
Roundtrip
found 3 days ago
Select Virgin Atlantic flight, departing Wed, Nov 26 from Southampton to San Francisco, returning Wed, Dec 3, priced at $948 found 3 days ago
Virgin Atlantic
Wed, Nov 26 - Wed, Dec 3
SOU
Southampton
SFO
San Francisco
$964 Roundtrip, found 3 days ago
$964
Roundtrip
found 3 days ago
Select Virgin Atlantic flight, departing Wed, Nov 26 from Southampton to San Francisco, returning Wed, Dec 3, priced at $964 found 3 days ago
Loganair
Wed, Nov 26 - Wed, Dec 3
SOU
Southampton
SFO
San Francisco
$965 Roundtrip, found 3 days ago
$965
Roundtrip
found 3 days ago
Select Loganair flight, departing Wed, Nov 26 from Southampton to San Francisco, returning Wed, Dec 3, priced at $965 found 3 days ago
British Airways
Wed, Nov 26 - Wed, Dec 3
SOU
Southampton
SFO
San Francisco
$985 Roundtrip, found 3 days ago
$985
Roundtrip
found 3 days ago
Select British Airways flight, departing Wed, Nov 26 from Southampton to San Francisco, returning Wed, Dec 3, priced at $985 found 3 days ago
KLM
Sat, Nov 1 - Sat, Nov 15
SOU
Southampton
SFO
San Francisco
$1,006 Roundtrip, found 2 hours ago
$1,006
Roundtrip
found 2 hours ago
Select KLM flight, departing Sat, Nov 1 from Southampton to San Francisco, returning Sat, Nov 15, priced at $1,006 found 2 hours ago

Frequently asked questions

How much does a flight from Southampton Airport (SOU) to San Francisco Intl. Airport (SFO) cost?
Grab a cheap one-way flight from $473 or cheap return flight from $799 from Southampton Airport (SOU) to San Francisco Intl. Airport (SFO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Southampton Airport (SOU) to San Francisco Intl. Airport (SFO)?
November is the most affordable month to fly from SOU to SFO. Traveling during an off-peak travel window is often the key to finding better fares.
Which airlines fly direct from Southampton Airport (SOU) to San Francisco Intl. Airport (SFO)?
Although Southampton (SOU) has no direct flights to San Francisco Intl. Airport (SFO), other airports have nonstop options. Departing from Heathrow Airport (LHR) will get you to San Francisco without any layovers.
What is the cheapest airline that flies from Southampton Airport (SOU) to San Francisco Intl. Airport (SFO)?
To find the cheapest airline that'll fly you from SOU to SFO, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Southampton Airport (SOU) to San Francisco Intl. Airport (SFO)?
There aren't any daily direct flights departing from Southampton Airport (SOU) to San Francisco Intl. Airport (SFO). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be on your way in no time.
What day of the week has the most flights from SOU to SFO?
Typically you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* But this can change based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Southampton Airport (SOU) to San Francisco Intl. Airport (SFO)?
To arrive at San Francisco Intl. Airport (SFO) on time, book a flight that takes off from Southampton Airport (SOU) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Southampton Airport (SOU) to San Francisco Intl. Airport (SFO) last-minute?
Holding off until just before your departure to book your flight from SOU to SFO generally means paying more. Although you may find some last-minute discounts, there's no guarantee. Keep your travel plans flexible to maximize your chances of landing a bargain.
Is it cheaper to book a SOU to SFO flight and hotel package?
Booking a SOU to SFO flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Select from our extensive range of hotels and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Southampton Airport (SOU) to San Francisco Intl. Airport (SFO)?
If you reserved your SOU to SFO flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more information.

Travel information

Origin airport
Southampton
Destination airport
San Francisco Intl.
Airlines serving
Aer Lingus, British Airways, Virgin Atlantic
Roundtrip price
$798
Distance
5353 mi

Book with confidence

Southampton to San Francisco Flights

The cheapest times to fly from Southampton to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Southampton to San Francisco are during the month of November. You can find some of the cheapest flights from Southampton to San Francisco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Southampton to San Francisco

Sunday is one of the best days to book for cheap flights from Southampton to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Southampton to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Southampton to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $473 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Southampton to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Southampton to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Southampton to San Francisco Flights

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*Available to One Key members.