$258 Cheap American Airlines flights Minneapolis (MSP) to Cozumel (CZM)

Scoring cheap one-way American Airlines flights from MSP to CZM from $258 on Expedia is a breeze --- just filter by "Price (lowest to highest)." Or check out our budget-friendly return fares from $500 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start your search for American Airlines flights from MSP to CZM about one month before you want to leave. The most affordable time to reserve an international flight is usually 18 to 29 days ahead of your departure date when you can save 17% versus booking four to five months in advance. No matter your ticket type or itinerary, the best day to book international airfare is usually Sunday. Friday is often the most expensive. Passengers who book on a Sunday can save 17% on average compared to those who book on a Friday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Early Morning" and "Morning" to find the earliest departures from MSP to CZM. Heading off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.