$99 Cheap Delta flights Denver (DEN) to Des Moines (DSM)

Finding cheap one-way Delta Air Lines flights from DEN to DSM from $99 on Expedia is easy — just filter by “Price (lowest to highest).” Or check out our budget-friendly return fares from $236 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for one-way or round-trip flights to Des Moines in January or December. You could find lower fares with Delta Air Lines during these quieter months.

Begin your search one to three months ahead of your departure date to score cheap fares on Delta Air Lines flights from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing spot on, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To figure out if there’s a direct route from DEN to DSM with Delta Air Lines or another airline, use our “Nonstop” filter when searching for flights.

Sort your results by “Morning” and “Early Morning” to find the earliest flights from DEN to DSM. Leaving early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Des Moines Intl. Airport (DSM) is the primary Des Moines gateway for Delta Air Lines flights from Denver Intl. Airport (DEN).

Flying from DEN to DSM with Delta Air Lines means enjoying a host of benefits, such as a rewarding loyalty program and an excellent in-flight experience. Plus, when booking through Expedia, One Key™ members can collect OneKeyCash™* to spend on select future travel purchases. That’s in addition to the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

Changes are typically free within 24 hours of making your booking, but your airline may add a charge after that time. For further information about modifying your reservation, go to your “Trips,” select your flight and click on “Manage Booking.” If you want the flexibility to make changes without extra charges, check the “Changes included” or “No cancel fee” filter when planning your next escape.