$229 Cheap Delta flights Minneapolis (MSP) to Des Moines (DSM)

Finding cheap one-way Delta Air Lines flights from MSP to DSM from $229 on Expedia couldn’t be easier — just filter by “Price (lowest to highest).” Alternatively, check out our affordable round-trip fares from $194 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for one-way or round-trip flights to Des Moines in January or December. You could find cheaper fares with Delta Air Lines during these off-peak times.

Look for cheap Delta Air Lines flights from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM) one to three months prior to your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and itinerary, the ideal day to book a domestic flight is generally Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Take off on one of Delta Air Lines’s 20 weekly direct flights from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM). To see your choices, enter your destination, origin and dates and hit search. Then use the “Nonstop” and “Airline” filters.

Depart Minneapolis - St. Paul Intl. Airport (MSP) for Des Moines Intl. Airport (DSM) on a nonstop Delta Air Lines flight, and you’ll be airborne for about 1h 18m.

If flexibility is what you’re after, Saturday offers the most choice for Delta Air Lines flights from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM). Take your pick of 3 different departures.

Leaving MSP at 10:10AM UTC-6, the first Delta Air Lines flight to DSM arrives at 11:31AM UTC-6. Flying early means you’ll be less likely to encounter delays or cancellations.* Don’t like early starts? The last Delta Air Lines flight from MSP to DSM departs at 7:59PM UTC-6 and touches down at 9:18PM UTC-6.*Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Delta Air Lines flights from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines come in to Des Moines Intl. Airport (DSM). This is the main gateway to this destination.

Delta Air Lines makes flying from MSP to DSM more comfortable with an excellent in-flight experience and a rewarding loyalty program. You also have the chance to earn points with Delta SkyMiles. Be sure to join our free One Key™ rewards program to earn OneKeyCash™*, which can be redeemed on future travel.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

Jet off on a Delta Air Lines flight from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM), and you’ll probably be on a Bombardier CRJ900. Keep in mind though, that the aircraft type can vary depending on operational demands.

Depending on your fare type, a fee is typically charged if you modify or cancel your booking more than 24 hours after it has been confirmed. To secure flexible plane tickets, select our “Changes included” or “No cancel fee” filter while searching for flights. For more information on canceling or changing your reservation, go to “Trips,” select your flight and tick “Manage Booking.”