Photo by Erik Rowley

Popular airlines from Seattle to Jefferson
- Alaska Airlines
Alaska Airlines
- Delta
Delta
- American Airlines
American Airlines
- United
United
- Southwest Airlines
Southwest Airlines
- Frontier Airlines
Frontier Airlines
- Plan, book, fly with confidence
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Cheap Flights from Seattle to Jefferson (SEA-DSM)
Prices were available within the past 7 days and start at $121 for one-way flights and $194 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Sep 11 - Sun, Sep 14
SEA
Seattle
DSM
Des Moines
$194 Roundtrip, found 1 day ago
$194
Roundtrip
found 1 day ago

Thu, Sep 18 - Thu, Sep 25
SEA
Seattle
DSM
Des Moines
$198 Roundtrip, found 1 day ago
$198
Roundtrip
found 1 day ago

Thu, Sep 4 - Fri, Sep 5
SEA
Seattle
DSM
Des Moines
$243 Roundtrip, found 5 days ago
$243
Roundtrip
found 5 days ago

Mon, Sep 22 - Fri, Sep 26
SEA
Seattle
DSM
Des Moines
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago

Mon, Sep 22 - Fri, Sep 26
SEA
Seattle
DSM
Des Moines
$260 Roundtrip, found 1 day ago
$260
Roundtrip
found 1 day ago

Tue, Oct 7 - Tue, Oct 21
SEA
Seattle
DSM
Des Moines
$297 Roundtrip, found 8 hours ago
$297
Roundtrip
found 8 hours ago
Find the cheapest month to fly from Seattle (SEA) to Des Moines (DSM)
May is typically the cheapest month to fly
From $198 - $506 per traveler.
Graph displaying average flight prices per month
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