$105 Cheap Flights from Knoxville (TYS) to Milwaukee (MKE)

View $105 flight on Wed, Mar 25, 2026Opens in a new window

Popular airlines from McGhee Tyson Airport (TYS) to General Mitchell Intl. Airport (MKE)

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Cheap Flights from Knoxville to Milwaukee (TYS-MKE)

Prices were available within the past 7 days and start at $105 for one-way flights and $209 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Sep 17 - Mon, Sep 22
TYS
Knoxville
MKE
Milwaukee
$209 Roundtrip, just found
$209
Roundtrip
just found
Select American Airlines flight, departing Wed, Sep 17 from Knoxville to Milwaukee, returning Mon, Sep 22, priced at $209 just found
United
Wed, Sep 17 - Mon, Sep 22
TYS
Knoxville
MKE
Milwaukee
$209 Roundtrip, just found
$209
Roundtrip
just found
Select United flight, departing Wed, Sep 17 from Knoxville to Milwaukee, returning Mon, Sep 22, priced at $209 just found
American Airlines
Fri, Sep 12 - Mon, Sep 15
TYS
Knoxville
MKE
Milwaukee
$214 Roundtrip, found 15 hours ago
$214
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Fri, Sep 12 from Knoxville to Milwaukee, returning Mon, Sep 15, priced at $214 found 15 hours ago
Southwest Airlines
Wed, Mar 11 - Wed, Mar 18
TYS
Knoxville
MKE
Milwaukee
$214 Roundtrip, found 2 days ago
$214
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Wed, Mar 11 from Knoxville to Milwaukee, returning Wed, Mar 18, priced at $214 found 2 days ago
Delta
Wed, Sep 17 - Mon, Sep 22
TYS
Knoxville
MKE
Milwaukee
$217 Roundtrip, just found
$217
Roundtrip
just found
Select Delta flight, departing Wed, Sep 17 from Knoxville to Milwaukee, returning Mon, Sep 22, priced at $217 just found
Delta
Tue, Sep 9 - Mon, Sep 22
TYS
Knoxville
MKE
Milwaukee
$218 Roundtrip, found 10 hours ago
$218
Roundtrip
found 10 hours ago
Select Delta flight, departing Tue, Sep 9 from Knoxville to Milwaukee, returning Mon, Sep 22, priced at $218 found 10 hours ago
Delta
Sat, Sep 6 - Tue, Sep 9
TYS
Knoxville
MKE
Milwaukee
$219 Roundtrip, found 10 hours ago
$219
Roundtrip
found 10 hours ago
Select Delta flight, departing Sat, Sep 6 from Knoxville to Milwaukee, returning Tue, Sep 9, priced at $219 found 10 hours ago
United
Wed, Sep 17 - Sun, Sep 21
TYS
Knoxville
MKE
Milwaukee
$226 Roundtrip, just found
$226
Roundtrip
just found
Select United flight, departing Wed, Sep 17 from Knoxville to Milwaukee, returning Sun, Sep 21, priced at $226 just found
United
Wed, Sep 17 - Sat, Sep 20
TYS
Knoxville
MKE
Milwaukee
$227 Roundtrip, found 1 day ago
$227
Roundtrip
found 1 day ago
Select United flight, departing Wed, Sep 17 from Knoxville to Milwaukee, returning Sat, Sep 20, priced at $227 found 1 day ago
United
Wed, Sep 17 - Mon, Sep 22
TYS
Knoxville
MKE
Milwaukee
$228 Roundtrip, just found
$228
Roundtrip
just found
Select United flight, departing Wed, Sep 17 from Knoxville to Milwaukee, returning Mon, Sep 22, priced at $228 just found

Find the cheapest month to fly from Knoxville (TYS) to Milwaukee (MKE)

November is typically the cheapest month to fly

From $198 - $552 per traveler.

Graph displaying average flight prices per month

Alternative airports near Milwaukee

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to General Mitchell Intl. MKE. Cheapest and Closest option available. Average driving time to city center is 13 minutes. Flights from $353
MKE
General Mitchell Intl.
CheapestClosest
Average driving time to city center13 min
Flights from $353
Flights from Knoxville (TYS) to Milwaukee (MKE)
Origin airport
McGhee Tyson
Destination airport
General Mitchell Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$208
Distance
535 mi

Knoxville to Milwaukee Flights

The cheapest times to fly from Knoxville to Milwaukee

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Milwaukee are during the month of September. You can find some of the cheapest flights from Knoxville to Milwaukee with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Milwaukee

Sunday is one of the best days to book for cheap flights from Knoxville to Milwaukee: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Milwaukee

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Milwaukee in 2025. You can also book with separate airlines for your outbound and return journeys, from $105 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Milwaukee flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Milwaukee airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to General Mitchell Intl. Airport (MKE) cost?
Get a cheap one-way flight from $105 or cheap return flight from $209 from McGhee Tyson Airport (TYS) to General Mitchell Intl. Airport (MKE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to General Mitchell Intl. Airport (MKE)?
Flying in September is a good way to save, as it's the cheapest month for flights between TYS and MKE. You'll often find the lowest prices during off-peak months.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to General Mitchell Intl. Airport (MKE)?
To find the cheapest airline flying from TYS to MKE, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from McGhee Tyson Airport (TYS) to General Mitchell Intl. Airport (MKE)?
You'll have to book a flight with a layover when traveling from McGhee Tyson Airport (TYS) to General Mitchell Intl. Airport (MKE). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from TYS to MKE?
Usually you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to General Mitchell Intl. Airport (MKE)?
To arrive at General Mitchell Intl. Airport (MKE) on schedule, select a flight that leaves from McGhee Tyson Airport (TYS) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to General Mitchell Intl. Airport (MKE) last-minute?
Waiting until just before your departure to book a ticket from TYS to MKE often results in higher prices. While you might find some last-minute discounts, there's no guarantee. Be flexible with your travel plans to maximize your chances of getting a bargain.
Is it cheaper to book a TYS to MKE flight and hotel package?
Compared with arranging hotels and flights separately, booking a TYS to MKE flight and hotel package with Expedia could result in significant savings. Better still, having it all in one place will take the stress out of travel planning. Simply secure your flights and choose from our wide range of stays, then customize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to General Mitchell Intl. Airport (MKE)?
In most cases, you're able to cancel or reschedule your TYS to MKE flight. However, additional fees may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you want more information, head to our Customer Service portal.

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*Available to One Key members.