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$135 Cheap Flights from Charleston (CHS) to St. Louis (STL)

View $135 flight on Tue, Jan 12, 2027Opens in a new window

Popular airlines from Charleston Intl. Airport (CHS) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Charleston to St. Louis (CHS-STL)

Prices were available within the past 7 days and start at $135 for one-way flights and $287 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Sat, Oct 10 - Sat, Oct 17
CHS
Charleston
STL
St. Louis
$287 Roundtrip, found 2 days ago
$287
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Sat, Oct 10 from Charleston to St. Louis, returning Sat, Oct 17, priced at $287 found 2 days ago
United
Thu, Nov 5 - Fri, Nov 6
CHS
Charleston
STL
St. Louis
$290 Roundtrip, found 3 days ago
$290
Roundtrip
found 3 days ago
Select United flight, departing Thu, Nov 5 from Charleston to St. Louis, returning Fri, Nov 6, priced at $290 found 3 days ago
Delta
Sat, Oct 17 - Mon, Oct 19
CHS
Charleston
STL
St. Louis
$292 Roundtrip, found 4 days ago
$292
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Oct 17 from Charleston to St. Louis, returning Mon, Oct 19, priced at $292 found 4 days ago
Southwest Airlines
Thu, Oct 15 - Mon, Oct 19
CHS
Charleston
STL
St. Louis
$351 Roundtrip, found 1 day ago
$351
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Oct 15 from Charleston to St. Louis, returning Mon, Oct 19, priced at $351 found 1 day ago
American Airlines
Tue, Feb 9 - Tue, Feb 16
CHS
Charleston
STL
St. Louis
$353 Roundtrip, found 21 hours ago
$353
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Tue, Feb 9 from Charleston to St. Louis, returning Tue, Feb 16, priced at $353 found 21 hours ago
Southwest Airlines
Thu, Oct 22 - Sat, Oct 24
CHS
Charleston
STL
St. Louis
$361 Roundtrip, found 1 day ago
$361
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Oct 22 from Charleston to St. Louis, returning Sat, Oct 24, priced at $361 found 1 day ago
Southwest Airlines
Tue, Nov 10 - Tue, Nov 17
CHS
Charleston
STL
St. Louis
$363 Roundtrip, found 1 day ago
$363
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Tue, Nov 10 from Charleston to St. Louis, returning Tue, Nov 17, priced at $363 found 1 day ago
Southwest Airlines
Wed, Oct 21 - Wed, Oct 28
CHS
Charleston
STL
St. Louis
$366 Roundtrip, found 1 day ago
$366
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Oct 21 from Charleston to St. Louis, returning Wed, Oct 28, priced at $366 found 1 day ago
Southwest Airlines
Tue, Nov 10 - Tue, Nov 17
CHS
Charleston
STL
St. Louis
$368 Roundtrip, found 1 day ago
$368
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Tue, Nov 10 from Charleston to St. Louis, returning Tue, Nov 17, priced at $368 found 1 day ago
Southwest Airlines
Thu, Oct 22 - Sat, Oct 24
CHS
Charleston
STL
St. Louis
$371 Roundtrip, found 1 day ago
$371
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Oct 22 from Charleston to St. Louis, returning Sat, Oct 24, priced at $371 found 1 day ago

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $487
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $487

What you need to know for your flight from Charleston Intl. to Lambert-St. Louis Intl.

Charleston (CHS) to St. Louis (STL) at a glance

Travel conveniently between Charleston (CHS) and St. Louis (STL) with a range of airlines offering this domestic short-haul route. Evaluate choices from both full-service and low-cost carriers to discover the itinerary that aligns with your budget, schedule, and travel preferences while you enjoy the renowned sights and neighborhoods of St. Louis. Get all the essential information for flights from Charleston International Airport (CHS) to Lambert-St. Louis International Airport (STL).

  • Fastest flight duration: around 2h 15m non-stop
  • Route distance: roughly 700 miles (1,130 km)
  • Flights per week: around 12 departures on average
  • Typical fares (one-way): economy tickets often range from $105–$395, depending on seasonality and how far ahead you book

Flights from Charleston International Airport (CHS) to Lambert-St. Louis International Airport (STL)

Based on recent travel bookings, the top airlines favored by travelers flying from Charleston to St. Louis typically offer both non-stop and one-stop options. Popular layover airports include Hartsfield-Jackson Atlanta International Airport (ATL) with a layover of about 1 hour and 30 minutes, Charlotte-Douglas International Airport (CLT) at approximately 1 hour and 15 minutes, and Nashville International Airport (BNA) with around a 50-minute layover. These choices allow you to balance price, total travel time, and cabin class for the ideal itinerary.

  • American Airlines: This full-service airline provides one-stop travel options, with one-way ticket prices generally between $105 and $390. It holds a share of about 38% of flights on this route, featuring an in-flight duration of 3 hours and 15 minutes, and a total travel time of approximately 4 hours and 30 minutes, including layovers.
  • Delta: As another full-service option, Delta offers one-stop flights with one-way fares usually ranging from $105 to $395. It represents around 31% of the departures along this route, with an in-flight time of 3 hours and 15 minutes and a total journey time of about 4 hours and 30 minutes, factoring in layovers.
  • Southwest Airlines: Known for its low-cost model, Southwest features both non-stop and one-stop services, with one-way fares typically falling between $110 and $400. This airline accounts for roughly 28% of the departures on this route, providing a direct travel option that usually takes 2 hours and 15 minutes.
  • United: Offering one-stop service, United is a full-service airline with one-way fares generally ranging from $170 to $415. It makes up approximately 4% of the departures on this route, featuring an in-flight duration of 3 hours and 15 minutes, and a total journey time of around 4 hours and 30 minutes, including layover periods.

Travelers flying from Charleston to St. Louis have the option to upgrade their flight. Delta offers first class and premium economy service, while American Airlines provides first class seating.

Best time to fly from Charleston (CHS) to St. Louis (STL)

The most popular months for travelers flying from Charleston to St. Louis are March, April, and December, when peak temperatures in St. Louis reach up to 56.1°F in April. If you prefer quieter travel, consider September, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 70.9°F. For better deals, February usually offers the lowest average one-way fare around $208. Flight availability peaks in December, with approximately 16 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 9 flights per week.

  • Cheapest time to fly: February usually offers good deals with average one-way fare around $208, roughly 7% cheaper than the yearly average.
  • More budget-friendly months to fly: September, August, and May typically offer average one-way fares of around $212.
  • Most flight options: December has the highest number of flights from Charleston to St. Louis, with approximately 16 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January31.6°F (-0.2°C)Average9$234
February34.9°F (1.6°C)Average12$208
March46.4°F (8.0°C)Moderately High12$235
April56.1°F (13.4°C)Moderately High13$242
May66.6°F (19.2°C)Moderately Low11$216
June76.1°F (24.5°C)Average12$218
July78.6°F (25.9°C)Average12$221
August77.0°F (25.0°C)Moderately Low11$215
September70.9°F (21.6°C)Moderately Low12$209
October58.6°F (14.8°C)Average15$232
November46.2°F (7.9°C)Average15$239
December37.8°F (3.2°C)Moderately High16$230

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Charleston (CHS) to St. Louis (STL)

  • Charleston to St. Louis (CHS-CPS): St. Louis Downtown Airport (CPS) is approximately 16 miles from Lambert-St. Louis International Airport (STL), offering convenient access to the city.

How to find the best prices for flights from Charleston (CHS) to St. Louis (STL)

Getting some of the best deals on flights from Charleston to St. Louis is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking at least two months in advance, although most travelers tend to book two to eight weeks ahead. Evening departures (6 PM to 12 AM) often offer lower prices, while morning flights (5 AM to 12 PM) are the most popular. Additionally, flying on Monday typically results in cheaper fares, although Friday is the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Lambert-St. Louis International Airport from Charleston International Airport

St. Louis welcomes travelers from Charleston with a range of transport options based on price, convenience, and proximity. For departures, Charleston International Airport is roughly a 15-minute drive (covering about 13 miles) from central Charleston. Here's how to reach St. Louis efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in St. Louis, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Lambert-St. Louis International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Lambert-St. Louis International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Lambert-St. Louis International Airport, Lambert Main Terminal Station, a metro station, is conveniently located just 0.1 miles away on foot, providing easy access to public transport.

Frequently asked questions

How much does a flight from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) cost?
You can find cheap one-way flights from $135 and cheap return flights from $287 Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) with Expedia. One-way flights usually range from $175 to $933, and return flights typically cost between $341 and $943. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
September is the cheapest month to fly from Charleston (CHS) to St. Louis (STL), with average round-trip fares around $298. This is about 22% lower than the average price throughout the year, as travel demand tends to decrease after the summer. Other cheap months to fly from Charleston to St. Louis include January and August.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Enter CHS to STL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
To find a cheap flight from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The best airline to fly with from Charleston, SC (CHS) to St. Louis, MO (STL) will differ from traveler to traveler. If you like to fly early, WN offers early morning flights. If price is the most important factor, WN typically offers the lowest fares. American Airlines offers the most daily flights from CHS to STL, which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
For flights from Charleston, SC (CHS) to St. Louis, MO (STL), September and August are the best months to travel. Return flights during these months average around $298, offering a great combination of affordability and flight options. August is perfect for summer travel, while September often sees fewer crowds, enhancing your experience.*Prices based on flights available on Expedia in the last year.
How many flights per day from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
There are approximately 1 nonstop flights per day from Charleston Intl. (CHS) to Lambert-St. Louis Intl. (STL). For more options, look at flights that include layovers.
What is the earliest flight from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The earliest flight from Charleston International Airport (CHS) to Lambert-St. Louis International Airport (STL) typically departs at around 5:00 AM, operated by American Airlines. This seasonal service is available in April, and an early departure can help you maximize your time in St. Louis. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The most popular departure times for flights from Charleston, SC (CHS) to St. Louis, MO (STL) are in the early morning, from 6am to 9am. About 27% of passengers prefer this time window. Many major carriers, including American Airlines, Delta, and Southwest Airlines, offer flights during this window. This timing works well because it allows you to arrive in St. Louis with plenty of time to start your day.
How long does it take to fly from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Direct flights from CHS to STL usually take about 2 hours 20 minutes, traveling roughly 706 miles. If you opt for a connecting flight, expect to add around 3 hours 10 minutes to your journey. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
First class seats are offered on the CHS to STL route. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight with Expedia?
It's easy to earn miles on a Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for St. Louis from Charleston Intl. (CHS)?
From Charleston Intl. (CHS), you can fly into Lambert-St. Louis Intl. (STL) to reach St. Louis. Some flights may connect through major hubs like Washington Dulles Intl. (IAD), Liberty Intl. (EWR), Baltimore Washington Intl. Thurgood Marshall (BWI) before reaching St. Louis. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) at the last minute?
Typically, booking a last minute flight from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package?
Securing a Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) St Louis Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
If you booked your Charleston, SC (CHS-Charleston Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Charleston Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$287
Distance
705 mi
Average flight time
1 hour 5 mins

Book with confidence

Charleston to St. Louis Flights

The cheapest times to fly from Charleston to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charleston to St. Louis are during the month of October. You can find some of the cheapest flights from Charleston to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charleston to St. Louis

Sunday is one of the best days to book for cheap flights from Charleston to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charleston to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charleston to St. Louis in 2026. You can also book with separate airlines for your outbound and return journeys, from $135 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charleston to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charleston to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Charleston to St. Louis Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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