$134 Cheap Flights from Charleston (CHS) to St. Louis (STL)

View $134 flight on Wed, Nov 12, 2025Opens in a new window

Popular airlines from Charleston Intl. Airport (CHS) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Charleston to St. Louis (CHS-STL)

Prices were available within the past 7 days and start at $134 for one-way flights and $246 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Thu, Nov 20 - Sun, Nov 23
CHS
Charleston
STL
St. Louis
$246 Roundtrip, found 6 hours ago
$246
Roundtrip
found 6 hours ago
Select Southwest Airlines flight, departing Thu, Nov 20 from Charleston to St. Louis, returning Sun, Nov 23, priced at $246 found 6 hours ago
Southwest Airlines
Thu, Nov 20 - Sun, Nov 23
CHS
Charleston
STL
St. Louis
$266 Roundtrip, found 6 hours ago
$266
Roundtrip
found 6 hours ago
Select Southwest Airlines flight, departing Thu, Nov 20 from Charleston to St. Louis, returning Sun, Nov 23, priced at $266 found 6 hours ago
Southwest Airlines
Tue, Dec 16 - Mon, Dec 22
CHS
Charleston
STL
St. Louis
$267 Roundtrip, found 4 hours ago
$267
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Tue, Dec 16 from Charleston to St. Louis, returning Mon, Dec 22, priced at $267 found 4 hours ago
American Airlines
Thu, Dec 4 - Mon, Dec 8
CHS
Charleston
STL
St. Louis
$267 Roundtrip, found 1 hour ago
$267
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Thu, Dec 4 from Charleston to St. Louis, returning Mon, Dec 8, priced at $267 found 1 hour ago
Delta
Thu, Dec 4 - Mon, Dec 8
CHS
Charleston
STL
St. Louis
$267 Roundtrip, found 1 hour ago
$267
Roundtrip
found 1 hour ago
Select Delta flight, departing Thu, Dec 4 from Charleston to St. Louis, returning Mon, Dec 8, priced at $267 found 1 hour ago
United
Thu, Dec 4 - Mon, Dec 8
CHS
Charleston
STL
St. Louis
$267 Roundtrip, found 1 hour ago
$267
Roundtrip
found 1 hour ago
Select United flight, departing Thu, Dec 4 from Charleston to St. Louis, returning Mon, Dec 8, priced at $267 found 1 hour ago
United
Thu, Feb 12 - Sun, Feb 15
CHS
Charleston
STL
St. Louis
$269 Roundtrip, found 4 hours ago
$269
Roundtrip
found 4 hours ago
Select United flight, departing Thu, Feb 12 from Charleston to St. Louis, returning Sun, Feb 15, priced at $269 found 4 hours ago
American Airlines
Thu, Dec 4 - Mon, Dec 8
CHS
Charleston
STL
St. Louis
$271 Roundtrip, found 1 hour ago
$271
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Thu, Dec 4 from Charleston to St. Louis, returning Mon, Dec 8, priced at $271 found 1 hour ago
Southwest Airlines
Tue, Dec 16 - Mon, Dec 22
CHS
Charleston
STL
St. Louis
$272 Roundtrip, found 4 hours ago
$272
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Tue, Dec 16 from Charleston to St. Louis, returning Mon, Dec 22, priced at $272 found 4 hours ago
United
Thu, Feb 12 - Sun, Feb 15
CHS
Charleston
STL
St. Louis
$274 Roundtrip, found 4 hours ago
$274
Roundtrip
found 4 hours ago
Select United flight, departing Thu, Feb 12 from Charleston to St. Louis, returning Sun, Feb 15, priced at $274 found 4 hours ago

Find the cheapest month to fly from Charleston (CHS) to St. Louis (STL)

October is typically the cheapest month to fly

From $166 - $748 per traveler.

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $362
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $362

Frequently asked questions

How much does a flight from Charleston Intl. Airport (CHS) to Lambert-St. Louis Intl. Airport (STL) cost?
Grab a cheap one-way flight from $134 or cheap return flight from $246 from Charleston Intl. Airport (CHS) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Charleston Intl. Airport (CHS) to Lambert-St. Louis Intl. Airport (STL)?
November is the least expensive month to fly from CHS to STL. Traveling during quieter months is often the key to finding a great deal.
What is the cheapest airline that flies from Charleston Intl. Airport (CHS) to Lambert-St. Louis Intl. Airport (STL)?
To find the cheapest airline that'll fly you from CHS to STL, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Charleston Intl. Airport (CHS) to Lambert-St. Louis Intl. Airport (STL)?
There aren't any daily nonstop flights from Charleston Intl. Airport (CHS) to Lambert-St. Louis Intl. Airport (STL). But you can book flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way before you know it.
What day of the week has the most flights from CHS to STL?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on a number of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from CHS to STL?
Southwest Airlines has the strongest track record for on-time direct flights from Charleston Intl. Airport (CHS) to Lambert-St. Louis Intl. Airport (STL), with an on-time score of 85%. Use the Expedia App to check your flight status before you take off and get immediate updates about any changes.
What is the best time to fly from Charleston Intl. Airport (CHS) to Lambert-St. Louis Intl. Airport (STL)?
To touch down at Lambert-St. Louis Intl. Airport (STL) without delays, select a flight that leaves from Charleston Intl. Airport (CHS) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Charleston Intl. Airport (CHS) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Waiting until right before your break to book your flight from CHS to STL often results in higher prices. While you may find some last-minute offers, they aren't always guaranteed. Keep your travel plans flexible to maximize your chances of scoring a bargain.
Is it cheaper to book a CHS to STL flight and hotel package?
Booking a CHS to STL flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Choose from our extensive range of hotels and then add activities, car rentals and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Charleston Intl. Airport (CHS) to Lambert-St. Louis Intl. Airport (STL)?
Typically, it's possible to reschedule or cancel your CHS to STL flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Charleston Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$246
Distance
705 mi

Book with confidence

Charleston to St. Louis Flights

The cheapest times to fly from Charleston to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charleston to St. Louis are during the month of November. You can find some of the cheapest flights from Charleston to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charleston to St. Louis

Sunday is one of the best days to book for cheap flights from Charleston to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charleston to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charleston to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $134 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charleston to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charleston to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Charleston to St. Louis Flights

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*Available to One Key members.