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$140 Cheap Flights from Memphis (MEM) to Des Moines (DSM)

Cheap Flights from Memphis to Des Moines (MEM-DSM)

Prices were available within the past 7 days and start at $140 for one-way flights and $279 for roundtrip, for the period specified. Prices and availability are subject to change.

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

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Memphis to Des Moines Flights

The cheapest times to fly from Memphis to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Memphis to Des Moines are during the month of September. You can find some of the cheapest flights from Memphis to Des Moines with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Memphis to Des Moines

Sunday is one of the best days to book for cheap flights from Memphis to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Memphis to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Memphis to Des Moines in 2026. You can also book with separate airlines for your outbound and return journeys, from $140 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Memphis to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Memphis to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently Asked Questions

How much does a flight from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.) cost?

You can find cheap one-way flights from $140 and cheap return flights $279 Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.) with Expedia. One-way flights generally range between $196 and $511, and roundtrip flights usually range from $324 to $846. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.) ticket fares go up or down.

*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.

What is the cheapest month to fly from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?

April is the cheapest month to fly from Memphis (MEM) to Des Moines (DSM), with average round-trip fares around $276. This fare is about 32% lower than the average price throughout the year, as April typically sees lower travel demand. Other economical months to fly from Memphis to Des Moines include October and November.

*Averages based on flights available on Expedia in the last year.

Which airlines fly direct from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?

Enter MEM to DSM and your travel dates, then apply the 'Nonstop' filter to see only direct flights.

What is the cheapest airline that flies from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?

Frontier Airlines is one of the cheapest airlines offering connecting flights from Memphis, TN (MEM) to Des Moines, IA (DSM), with round-trip tickets starting from around $273. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.

*Prices based on flights available on Expedia in the last year.

How do I find cheap flights from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?

To find a cheap flight from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.

What is the best time to fly from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?

For flights from Memphis, TN (MEM) to Des Moines, IA (DSM), the best times to fly are in April and November. Both months offer average return flight prices around $276, making them budget-friendly options. April brings mild spring weather, while November offers a quieter travel experience, allowing you to enjoy your trip without the hustle and bustle.

*Prices based on flights available on Expedia in the last year.

What is the earliest flight from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?

The earliest flight from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.) typically departs at around 5:00 AM, operated by American Airlines. This seasonal service is available in April and May, giving you a great opportunity to maximize your time in Iowa. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.

What are the most popular departure times for flights from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?

The most popular departure times for flights from Memphis (MEM) to Des Moines (DSM) are in the early morning, from 6am to 9am. About 33% of passengers prefer this time window. Many major carriers, including American Airlines, Delta, and United Airlines, offer flights during this window. This timing works well because it allows you to arrive in Des Moines with a full day ahead of you.

How long does it take to fly from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?

Flying from MEM to DSM with a connection usually takes about 5 hours 20 minutes, traveling roughly 490 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.

Can you fly business or first class from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?

You can fly first class between MEM and DSM. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight with Expedia?

It's easy to earn miles on a Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

What airports do you fly into for Des Moines from Memphis Intl. (MEM)?

If you're planning to travel to Des Moines from Memphis Intl. (MEM), you can fly into Des Moines Intl. (DSM) Some flights may connect through major hubs like William P. Hobby (HOU), Love Field (DAL), Midway Intl. (MDW) before reaching Des Moines. Compare routes and airports on Expedia to find the best flight options for your travel plans.

Is it cheaper to buy a plane ticket from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.) at the last minute?

Typically, booking a last minute flight from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.

Is it cheaper to book a Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight and hotel package?

Securing a Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.) Des Moines Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.

Can I cancel or change the date of my flight from Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?

If you booked your Memphis, TN (MEM-Memphis Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Memphis International Airport
Destination airport
Des Moines International Airport
Distance
490 miles away
Airlines serving
Delta, American Airlines, Southwest Airlines, United
Popular airline
Delta
Roundtrip price
$279
*Available to One Key members.