$423 Cheap Flights from Mexicali (MXL) to San Francisco (SFO)

View $423 flight on Wed, Nov 19, 2025Opens in a new window

Popular airlines from Mexicali, Baja California Norte (MXL-General Rodolfo Sanchez Taboada Intl.) to San Francisco Intl. Airport (SFO)

Cheap Flights from Mexicali to San Francisco (MXL-SFO)

Prices were available within the past 7 days and start at $423 for one-way flights and $813 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Tue, Oct 28 - Tue, Nov 4
MXL
Mexicali
SFO
San Francisco
$813 Roundtrip, found 1 day ago
$813
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Tue, Oct 28 from Mexicali to San Francisco, returning Tue, Nov 4, priced at $813 found 1 day ago
Aeromexico
Thu, Jan 8 - Mon, Jan 26
MXL
Mexicali
SFO
San Francisco
$814 Roundtrip, found 1 day ago
$814
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Thu, Jan 8 from Mexicali to San Francisco, returning Mon, Jan 26, priced at $814 found 1 day ago
Aeromexico
Wed, Nov 12 - Wed, Nov 19
MXL
Mexicali
SFO
San Francisco
$822 Roundtrip, found 20 hours ago
$822
Roundtrip
found 20 hours ago
Select Aeromexico flight, departing Wed, Nov 12 from Mexicali to San Francisco, returning Wed, Nov 19, priced at $822 found 20 hours ago
Aeromexico
Tue, Oct 28 - Sun, Nov 9
MXL
Mexicali
SFO
San Francisco
$835 Roundtrip, found 1 day ago
$835
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Tue, Oct 28 from Mexicali to San Francisco, returning Sun, Nov 9, priced at $835 found 1 day ago
Aeromexico
Wed, Nov 12 - Wed, Nov 19
MXL
Mexicali
SFO
San Francisco
$838 Roundtrip, found 20 hours ago
$838
Roundtrip
found 20 hours ago
Select Aeromexico flight, departing Wed, Nov 12 from Mexicali to San Francisco, returning Wed, Nov 19, priced at $838 found 20 hours ago
Aeromexico
Sat, Nov 22 - Fri, Nov 28
MXL
Mexicali
SFO
San Francisco
$857 Roundtrip, found 2 days ago
$857
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Sat, Nov 22 from Mexicali to San Francisco, returning Fri, Nov 28, priced at $857 found 2 days ago
Aeromexico
Sat, Nov 8 - Sat, Nov 15
MXL
Mexicali
SFO
San Francisco
$867 Roundtrip, found 6 days ago
$867
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Sat, Nov 8 from Mexicali to San Francisco, returning Sat, Nov 15, priced at $867 found 6 days ago
Aeromexico
Thu, Oct 30 - Tue, Nov 4
MXL
Mexicali
SFO
San Francisco
$868 Roundtrip, found 1 day ago
$868
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Thu, Oct 30 from Mexicali to San Francisco, returning Tue, Nov 4, priced at $868 found 1 day ago
Aeromexico
Thu, Oct 30 - Thu, Nov 6
MXL
Mexicali
SFO
San Francisco
$878 Roundtrip, found 1 day ago
$878
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Thu, Oct 30 from Mexicali to San Francisco, returning Thu, Nov 6, priced at $878 found 1 day ago
Aeromexico
Sat, Nov 1 - Tue, Nov 4
MXL
Mexicali
SFO
San Francisco
$891 Roundtrip, found 1 day ago
$891
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Sat, Nov 1 from Mexicali to San Francisco, returning Tue, Nov 4, priced at $891 found 1 day ago
Flights from Mexicali (MXL) to San Francisco (SFO)
Origin airport
General Rodolfo Sanchez Taboada Intl.
Destination airport
San Francisco Intl.
Airlines serving
Aeromexico
Roundtrip price
$812
Distance
530 mi

Mexicali to San Francisco Flights

The cheapest times to fly from Mexicali to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mexicali to San Francisco are during the month of October. You can find some of the cheapest flights from Mexicali to San Francisco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mexicali to San Francisco

Sunday is one of the best days to book for cheap flights from Mexicali to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mexicali to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mexicali to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $423 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mexicali to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mexicali to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Francisco Intl. Airport (SFO) cost?
Snag a cheap one-way flight from $423 or cheap return flight from $813 from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Francisco Intl. Airport (SFO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Francisco Intl. Airport (SFO)?
Planning your trip for October is a good way to save, as it's the cheapest month for flights between MXL and SFO. You'll often find the lowest fares during off-peak months.
What is the cheapest airline that flies from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Francisco Intl. Airport (SFO)?
To find the cheapest airline that'll fly you from MXL to SFO, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Francisco Intl. Airport (SFO)?
Nonstop flights from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Francisco Intl. Airport (SFO) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MXL to SFO?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Francisco Intl. Airport (SFO)?
To avoid potential delays on the General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Francisco Intl. Airport (SFO) route, aim to travel before 3 PM. Later departures have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Francisco Intl. Airport (SFO) last-minute?
Booking your plane ticket from MXL to SFO right before your getaway is generally more expensive. But if you're flexible with your schedule, you could land a cheap last-minute fare.
Is it cheaper to book a MXL to SFO flight and hotel package?
Compared with arranging hotels and flights separately, booking a MXL to SFO flight and hotel package with Expedia could lead to significant savings. What's more, managing everything in one place will take the stress out of planning your trip. Simply pick your flights and select from our wide range of hotels, then personalize your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Francisco Intl. Airport (SFO)?
If you booked your MXL to SFO flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for further details.

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*Available to One Key members.