$471 Cheap Flights from Reynosa (REX) to San Francisco (SFO)

View $471 flight on Tue, Nov 11, 2025Opens in a new window

Popular airlines from Reynosa, Tamaulipas (REX-General Lucio Blanco Intl.) to San Francisco Intl. Airport (SFO)

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Cheap Flights from Reynosa to San Francisco (REX-SFO)

Prices were available within the past 7 days and start at $471 for one-way flights and $789 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Tue, Nov 11 - Tue, Nov 18
REX
Reynosa
SFO
San Francisco
$789 Roundtrip, found 2 days ago
$789
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Nov 11 from Reynosa to San Francisco, returning Tue, Nov 18, priced at $789 found 2 days ago
Aeromexico
Tue, Nov 11 - Tue, Nov 18
REX
Reynosa
SFO
San Francisco
$889 Roundtrip, found 2 days ago
$889
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Nov 11 from Reynosa to San Francisco, returning Tue, Nov 18, priced at $889 found 2 days ago
Aeromexico
Tue, Nov 11 - Tue, Nov 18
REX
Reynosa
SFO
San Francisco
$988 Roundtrip, found 2 days ago
$988
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Nov 11 from Reynosa to San Francisco, returning Tue, Nov 18, priced at $988 found 2 days ago
Aeromexico
Tue, Nov 11 - Tue, Nov 18
REX
Reynosa
SFO
San Francisco
$992 Roundtrip, found 2 days ago
$992
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Nov 11 from Reynosa to San Francisco, returning Tue, Nov 18, priced at $992 found 2 days ago
Aeromexico
Tue, Nov 11 - Tue, Nov 18
REX
Reynosa
SFO
San Francisco
$1,055 Roundtrip, found 2 days ago
$1,055
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Nov 11 from Reynosa to San Francisco, returning Tue, Nov 18, priced at $1,055 found 2 days ago
Aeromexico
Tue, Nov 11 - Tue, Nov 18
REX
Reynosa
SFO
San Francisco
$1,085 Roundtrip, found 2 days ago
$1,085
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Nov 11 from Reynosa to San Francisco, returning Tue, Nov 18, priced at $1,085 found 2 days ago
Aeromexico
Tue, Nov 11 - Tue, Nov 18
REX
Reynosa
SFO
San Francisco
$1,089 Roundtrip, found 2 days ago
$1,089
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Nov 11 from Reynosa to San Francisco, returning Tue, Nov 18, priced at $1,089 found 2 days ago
Aeromexico
Tue, Nov 11 - Tue, Nov 18
REX
Reynosa
SFO
San Francisco
$1,098 Roundtrip, found 2 days ago
$1,098
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Nov 11 from Reynosa to San Francisco, returning Tue, Nov 18, priced at $1,098 found 2 days ago
Aeromexico
Tue, Nov 11 - Tue, Nov 18
REX
Reynosa
SFO
San Francisco
$1,160 Roundtrip, found 2 days ago
$1,160
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Nov 11 from Reynosa to San Francisco, returning Tue, Nov 18, priced at $1,160 found 2 days ago
Aeromexico
Tue, Nov 11 - Tue, Nov 18
REX
Reynosa
SFO
San Francisco
$1,172 Roundtrip, found 2 days ago
$1,172
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Nov 11 from Reynosa to San Francisco, returning Tue, Nov 18, priced at $1,172 found 2 days ago

Frequently asked questions

How much does a flight from General Lucio Blanco Intl. Airport (REX) to San Francisco Intl. Airport (SFO) cost?
Snag a cheap one-way flight from $471 or cheap return flight from $789 from General Lucio Blanco Intl. Airport (REX) to San Francisco Intl. Airport (SFO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from General Lucio Blanco Intl. Airport (REX) to San Francisco Intl. Airport (SFO)?
Flying in November may help you find better deals, as it's the cheapest month for flights between REX and SFO. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from General Lucio Blanco Intl. Airport (REX) to San Francisco Intl. Airport (SFO)?
To find the cheapest airline that'll fly you from REX to SFO, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from General Lucio Blanco Intl. Airport (REX) to San Francisco Intl. Airport (SFO)?
You'll have to hop on a flight with a layover if you're traveling from General Lucio Blanco Intl. Airport (REX) to San Francisco Intl. Airport (SFO). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from REX to SFO?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from General Lucio Blanco Intl. Airport (REX) to San Francisco Intl. Airport (SFO)?
To touch down at San Francisco Intl. Airport (SFO) without delays, select a flight that takes off from General Lucio Blanco Intl. Airport (REX) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from General Lucio Blanco Intl. Airport (REX) to San Francisco Intl. Airport (SFO) last-minute?
Last-minute bookings from REX to SFO are typically more expensive. To secure the best prices, start searching for flights as early as possible. That being said, if you're flexible with your travel dates, it's possible to find a cheap ticket just before your departure.
Is it cheaper to book a REX to SFO flight and hotel package?
Securing a REX to SFO flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Select from our wide range of stays and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from General Lucio Blanco Intl. Airport (REX) to San Francisco Intl. Airport (SFO)?
Usually, it's possible to cancel or reschedule your REX to SFO flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Travel information

Origin airport
General Lucio Blanco Intl.
Destination airport
San Francisco Intl.
Airlines serving
Aeromexico
Roundtrip price
$788
Distance
1622 mi

Book with confidence

Book with confidence

Reynosa to San Francisco Flights

The cheapest times to fly from Reynosa to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Reynosa to San Francisco are during the month of November. You can find some of the cheapest flights from Reynosa to San Francisco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Reynosa to San Francisco

Sunday is one of the best days to book for cheap flights from Reynosa to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Reynosa to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Reynosa to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $471 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Reynosa to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Reynosa to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Reynosa to San Francisco Flights

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*Available to One Key members.