A street with houses, a water tower, and a banana tree.

Find 4 Star Hotels in Des Peres, MO from $113

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Check availability on Des Peres 4 Star Hotels

Tonight
Oct 26 - Oct 27
Tomorrow
Oct 27 - Oct 28
This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Des Peres 4-star hotels

A lobby with a sofa, two armchairs, a coffee table, and a staircase.
A park with a pathway, trees, and a modern sculpture.
A spacious lobby with a sectional sofa, a white armchair, and a glass coffee table. There is a dining area in the background with a chandelier.
A rooftop lounge with large windows, red seating, and a view of the cityscape.

1. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
Downtown St. Louis
United States
Tracy
$125 nightly
$148 total
Nov 25 - Nov 26
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
A bar area with high wooden ceilings, a large mural, and a variety of seating options including tables and bar stools.
A modern lobby with a large glass sphere, seating areas, and a reception desk.
Bar (on property)
Spa

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
United States
A.R.
$148 nightly
$173 total
Nov 15 - Nov 16
Total with taxes and fees
21C Museum Hotel St Louis
A buffet with fruits, pastries, and beverages.
A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.
The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.
A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

3. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
Berkeley
United States
Luther
$111 nightly
$130 total
Nov 20 - Nov 21
Total with taxes and fees
Renaissance St. Louis Airport Hotel
A rooftop restaurant with round tables, chairs, and a view of the city.
A modern lobby with a staircase, seating area, and wall-mounted artwork.
A hotel with a prominent sign reading "MOONRISE."
A modern lobby with a staircase, seating area, and an exit sign.

4. Moonrise Hotel

Moonrise Hotel
Delmar Loop
United States
Jennifer
$151 nightly
$180 total
Oct 27 - Oct 28
Total with taxes and fees
Moonrise Hotel
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.
The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.
A modern living room with a sofa, coffee table, and bookshelves.
A restaurant with tables set for dining, a kitchen in the background, and hanging light fixtures.

5. Live by Loews - St.Louis

Live by Loews - St.Louis
Downtown St. Louis
United States
brandon
$139 nightly
$165 total
Nov 15 - Nov 16
Total with taxes and fees
Live by Loews - St.Louis
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A bakery display case with various pastries and cakes.
A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
United States
Samuel
$161 nightly
$188 total
Nov 25 - Nov 26
Total with taxes and fees
Ameristar Casino Resort and Spa
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.
A grand lobby with a central seating area, a staircase, and a decorative ceiling.
A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.

7. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
United States
Kristina
$159 nightly
$188 total
Nov 22 - Nov 23
Total with taxes and fees
The Royal Sonesta Chase Park Plaza St. Louis
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.
A bar area with a round table, ice-filled glasses, bottles of champagne, and decorative plants.
A long dining table set with candles, glassware, and white flowers, suggesting a formal dining experience.
An outdoor seating area with modern furniture, a metal railing, and a view of surrounding buildings.

8. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
Clayton
United States
Marsha
$152 nightly
$179 total
Nov 15 - Nov 16
Total with taxes and fees
Le Méridien St. Louis Clayton
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.
A modern restaurant interior with high tables, chairs, and a central bar area.
A bar area with wooden paneling, a counter, and multiple stools.
A lobby with wooden paneling, a green wall, and two armchairs.

9. The Westin St. Louis

The Westin St. Louis
Downtown St. Louis
United States
Stacy
$131 nightly
$153 total
Nov 15 - Nov 16
Total with taxes and fees
The Westin St. Louis
A modern dining area with round tables, orange chairs, and a decorative wall with pottery.
A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.
A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.
A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.

10. Marriott St. Louis Airport

Marriott St. Louis Airport
Edmundson
United States
Ravyn
$143 nightly
$172 total
Nov 13 - Nov 14
Total with taxes and fees
Marriott St. Louis Airport
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.
A casino with multiple gaming tables and slot machines.
A spacious hotel lobby with a central seating area, multiple armchairs, and a bar.
A luxurious hotel lobby with a grand stage, elegant seating, and a large chandelier.

11. River City Casino & Hotel

River City Casino & Hotel
St. Louis
United States
jodi
$100 nightly
$118 total
Nov 10 - Nov 11
Total with taxes and fees
River City Casino & Hotel
A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.
Lobby
A grand hall with rows of chairs arranged for an event, a central floral arrangement, and a large chandelier.
A spacious interior with a central staircase, large windows, and hanging chandeliers.

12. Marriott St. Louis Grand

Marriott St. Louis Grand
Downtown St. Louis
United States
Leonor
$127 nightly
$151 total
Nov 22 - Nov 23
Total with taxes and fees
Marriott St. Louis Grand
A bar area with a central bar, multiple stools, and a chandelier.
A grand lobby with a bar area, chandeliers, and seating.
A grand lobby with a large chandelier, a bar area, and classical architecture.
A spacious lobby with a high ceiling, ornate chandeliers, and a seating area with sofas and armchairs.

13. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Downtown St. Louis
United States
Anastasia
$95 nightly
$113 total
Nov 23 - Nov 24
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.
A spa bath with a sign indicating a capacity of 8 persons.
A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

14. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
United States
Stacey Rochelle
$128 nightly
$152 total
Nov 1 - Nov 2
Total with taxes and fees
Drury Plaza Hotel St. Louis Brentwood
A cozy lounge area with leather sofas, a fireplace, and a bar counter.
A restaurant with a central bar area, seating arrangements, and a fireplace.
A traditional building with a stone facade, large windows, and outdoor seating area with wicker furniture.
An outdoor patio area with a pool, red umbrellas, and seating arrangements.

15. The Cheshire

The Cheshire
Richmond Heights
United States
Matthew
$148 nightly
$176 total
Nov 15 - Nov 16
Total with taxes and fees
The Cheshire
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.
A bar area with a long counter, multiple stools, and a television mounted on the wall.
A buffet area with various food items and a self-service station.
An indoor swimming pool area with lounge chairs, a small table, and potted plants.

16. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
Downtown St. Louis
United States
Megan
$114 nightly
$135 total
Nov 23 - Nov 24
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown
A rooftop terrace with outdoor seating, string lights, and a city skyline view.
A multi-story hotel with a classic architectural style, featuring a prominent entrance and a series of uniformly lit windows.
A modern hotel room with a large window, a bathtub, and a unique eye-themed pillow.
A woman sitting on a green sofa in a modern lobby with a staircase and a large framed artwork on the wall.

17. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
United States
Skylee
$103 nightly
$122 total
Nov 22 - Nov 23
Total with taxes and fees
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
A modern lounge area with a central fire feature, seating, and large windows offering a city view.
An outdoor seating area with a green bar, lounge chairs, and a view of the cityscape at dusk.
A bar area with seating and a bar counter, large windows, and a high ceiling with exposed beams.
A bar area with a long counter, multiple seating options including bar stools and cushioned chairs, and a television screen mounted above the bar.

18. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
Downtown St. Louis
United States
kristen
$139 nightly
$165 total
Nov 22 - Nov 23
Total with taxes and fees
Hilton St. Louis at the Ballpark
A spacious lobby with high arched ceilings, ornate columns, and a central fountain.
A spacious lobby with high ceilings, ornate green and gold detailing, and a central bar area.
A restaurant with tables and chairs, large windows, and a view of the street.
A multi-level hotel lobby with a grand staircase, a reception desk, and a seating area.

19. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
Downtown West
United States
Donna
$155 nightly
$184 total
Nov 22 - Nov 23
Total with taxes and fees
St. Louis Union Station Hotel, Curio Collection by Hilton
A spacious lobby with modern seating arrangements, a large chandelier, and a view of the cityscape through large windows.
A hotel room with two beds, a TV, a desk, and a chair.
A lobby with a clock, a sign for The Merchants' Laclede National Bank, and a security vault.
A couple exiting a building through ornate black gates.

20. Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
Downtown St. Louis
United States
Mary
$110 nightly
$128 total
Nov 15 - Nov 16
Total with taxes and fees
Hilton Pennywell St. Louis at the Arch
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Des Peres.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
$375 nightly
$438 total
Oct 27 - Oct 28
Total with taxes and fees
Four Seasons Hotel St Louis
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
$579 nightly
$676 total
Nov 1 - Nov 2
Total with taxes and fees
9.2/10 Wonderful! (586 reviews)
The Ritz-Carlton, St. Louis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Des Peres

Just minutes from St. Louis, this charming suburb offers family-friendly recreation at Sugar Creek Park with playgrounds and walking trails. Spend an afternoon exploring the fascinating Museum of Transportation where vintage trains and automobiles bring America's transit history to life.

See all hotels in Des Peres
A museum exhibit with vintage vehicles including a 1934 Ford Phalet car and a fire truck.

Top Des Peres Hotel Reviews

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

8/10 Good
"Over all, our stay was fine. Staff was very kind. We visited for an event that took place in one of the 2nd floor ballrooms where I was a vendor. The food served for us at breakfast was delicious. However, one of the first things that happened to me upon getting to our room was my mother coming out from the bathroom and going, "Uh, someone pooped in our shower?". Turns out, it was just a very convincing rust spot, so I'm glad we didn't complain and look completely foolish, but still. The beds were comfortable though, and the water ran quite hot. The halls are a bit of a twist-and-turn to navigate and we were on the side of the building facing the MLK Bridge, which is a nice view. You are, however, literally right next to the Arch. All you have to do is step outside on Chestnut street and look to your left. The bar and common areas downstairs were nicely furnished; I spent some time with my laptop down there while my travel companions turned in early. Interesting spot to people watch. They also have a designated area for DoorDashers and other delivery folks to leave items, but I was usually waiting for them right at the door. My only complaint is that parking is far too high! We parked down the street a bit instead, and other than our GPS leading us on the longest route back to the hotel imaginable, we saved at least $50 on our two night stay, and the garage was perfectly walkable, even with our luggage and vending supplies."
Samantha 2-night trip
Posted 1 hour ago
Hyatt Regency St. Louis at The Arch
Live by Loews - St.Louis

Live by Loews - St.Louis

10/10 Excellent
"This was the perfect spot to stay for the weekend. Came up for the Hockey game and wanted a unique experience of downtown STL while also feeling safe. The staff is extremely welcoming and the overall feel is not overwhelming, it’s super clean, and being right next Busch Ballpark is awesome with great views. Parking deck is tight but easy to access. Cannot wait to go back during a baseball game and stay here."
Andrew 1-night trip
Posted 7 hours ago
Live by Loews - St.Louis

Find out more about Des Peres

Des Peres Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Des Peres, St. Louis are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Des Peres 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Des Peres. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Des Peres, St. Louis, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Des Peres hotels offer everything your heart desires.

Frequently asked questions

What are the best 4-star hotels in Des Peres?
Hilton St. Louis Frontenac is a 4-star hotel in Des Peres that ranks highly among Expedia guests. Concierge services and limousine services are some of its many amenities. Travelers also love staying at Le Méridien St. Louis Clayton. From a swimming pool to a terrace, it comes with conveniences that cater to all aspects of your relaxation and enjoyment.
How much does it cost to stay in a 4-star hotel in Des Peres?
With Expedia's search and sort filters, bagging a great deal on a 4-star hotel in Des Peres just got easier. Start by entering your chosen arrival date and length of your break. Then sort the results by price and choose a property that best suits your style and budget.
  • Search for the lowest price from $438
What's the difference between 5-star and 4-star hotels in Des Peres?
If you decide to vacation at a 4-star hotel in Des Peres, you'll usually find loads of conveniences to ensure you're relaxed, such as a gym, restaurant and pool. You can enjoy high-quality service and deluxe accommodations. Choose a 5-star hotel and you'll have access to a few more perks — think concierge assistance, on-site spas and nightly turndown services. You'll most likely get additional amenities and exclusive services at a 5-star getaway, but both are terrific options for luxury travelers.

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