A street with houses, a water tower, and a banana tree.

Find 4 Star Hotels in Des Peres, MO from $132

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Check availability on Des Peres 4 Star Hotels

Tonight
Oct 18 - Oct 19
Tomorrow
Oct 19 - Oct 20
Next weekend
Oct 23 - Oct 25
In two weeks
Oct 30 - Nov 1

Our top choices for Des Peres 4-star hotels

A buffet with fruits, pastries, and beverages.
A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.
A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.
The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.

1. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
Berkeley
United States
Anthony
$118 nightly
$138 total
Nov 15 - Nov 16
Total with taxes and fees
Renaissance St. Louis Airport Hotel
A lobby with a sofa, two armchairs, a coffee table, and a staircase.
A park with a pathway, trees, and a modern sculpture.
A modern hotel room with a large window, a flat-screen TV mounted on the wall, a round dining table with chairs, and a patterned rug.
A spacious lobby with a sectional sofa, a white armchair, and a glass coffee table. There is a dining area in the background with a chandelier.

2. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
Downtown St. Louis
United States
David
$134 nightly
$158 total
Oct 30 - Oct 31
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A spacious lobby with multiple seating areas, a pool table, and artwork on the walls.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.

3. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
United States
Zane
$148 nightly
$173 total
Nov 15 - Nov 16
Total with taxes and fees
21C Museum Hotel St Louis
A cozy lounge area with leather sofas, a fireplace, and a bar counter.
An outdoor patio area with a pool, red umbrellas, and seating arrangements.
A traditional building with a stone facade, large windows, and outdoor seating area with wicker furniture.
A restaurant with a central bar area, seating arrangements, and a fireplace.

4. The Cheshire

The Cheshire
Richmond Heights
United States
Matthew
$148 nightly
$176 total
Oct 25 - Oct 26
Total with taxes and fees
The Cheshire
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.
The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.
A restaurant with tables set for dining, a kitchen in the background, and hanging light fixtures.
A modern bar area with a central fire feature, bar stools, and seating.

5. Live by Loews - St.Louis

Live by Loews - St.Louis
Downtown St. Louis
United States
Molly
$139 nightly
$165 total
Nov 15 - Nov 16
Total with taxes and fees
Live by Loews - St.Louis
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.
A lobby with wooden paneling, a green wall, and two armchairs.
A modern restaurant interior with high tables, chairs, and a central bar area.
A bar area with wooden paneling, a counter, and multiple stools.

6. The Westin St. Louis

The Westin St. Louis
Downtown St. Louis
United States
Stacy
$131 nightly
$153 total
Nov 15 - Nov 16
Total with taxes and fees
The Westin St. Louis
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
A bar area with a marble counter, bar stools, and a variety of liquor bottles.
A grand lobby with a central seating area, a staircase, and a decorative ceiling.
A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.

7. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
United States
Kristina
$186 nightly
$219 total
Nov 15 - Nov 16
Total with taxes and fees
The Royal Sonesta Chase Park Plaza St. Louis
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.
A large hotel with a prominent "RIVER CITY" sign.
A casino with multiple gaming tables and slot machines.
A luxurious hotel lobby with a grand stage, elegant seating, and a large chandelier.

8. River City Casino & Hotel

River City Casino & Hotel
St. Louis
United States
jodi
$116 nightly
$137 total
Nov 16 - Nov 17
Total with taxes and fees
River City Casino & Hotel
A modern hotel room with a blue accent wall, a dining area with a round table and chairs, a kitchenette, and a bed with a blue headboard.
A woman sitting on a green sofa in a modern lobby with a staircase and a large framed artwork on the wall.
A modern lounge area with a central cylindrical light fixture, white seating, and artwork on the walls.
A multi-story hotel with a classic architectural style, featuring a prominent entrance and a series of uniformly lit windows.

9. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
United States
Skylee
$126 nightly
$149 total
Oct 25 - Oct 26
Total with taxes and fees
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

10. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
United States
Melissa
$163 nightly
$190 total
Nov 18 - Nov 19
Total with taxes and fees
Ameristar Casino Resort and Spa
A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.
Lobby
A spacious lobby with a high ceiling, a bar area, multiple seating arrangements, and a large screen displaying a sports event.
A spacious interior with a central staircase, large windows, and hanging chandeliers.

11. Marriott St. Louis Grand

Marriott St. Louis Grand
Downtown St. Louis
United States
Andrew
$152 nightly
$181 total
Oct 30 - Oct 31
Total with taxes and fees
Marriott St. Louis Grand
A rooftop restaurant with round tables, chairs, and a view of the city.
A modern lobby with a staircase, seating area, and an exit sign.
A modern lobby with a staircase, seating area, and wall-mounted artwork.
A rooftop terrace with seating areas, a decorative moon sculpture, and string lights.

12. Moonrise Hotel

Moonrise Hotel
Delmar Loop
United States
Jessie
$165 nightly
$196 total
Nov 18 - Nov 19
Total with taxes and fees
Moonrise Hotel
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.
A spa bath with a sign indicating a capacity of 8 persons.
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

13. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
United States
angelia
$128 nightly
$152 total
Nov 1 - Nov 2
Total with taxes and fees
Drury Plaza Hotel St. Louis Brentwood
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.
A buffet area with various food items and a self-service station.
A spacious lobby with striped chairs, a central coffee table, and large potted plants.
A bar area with a long counter, multiple stools, and a television mounted on the wall.

14. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
Downtown St. Louis
United Kingdom
Luke
$118 nightly
$141 total
Oct 26 - Oct 27
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown
A modern hotel room with a large dining table, comfortable seating, a sofa, and a television.
A modern lounge area with a central fire feature, seating, and large windows offering a city view.
A hotel room with a bed, a sofa, a red ottoman, a nightstand, a lamp, and a view of a cityscape through large windows.
A modern hotel with a prominent Hilton sign, surrounded by a spacious parking lot and a well-maintained lawn.

15. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
Downtown St. Louis
United States
kristen
$147 nightly
$175 total
Oct 28 - Oct 29
Total with taxes and fees
Hilton St. Louis at the Ballpark
A brick building with a tower, large windows, and a fountain in the garden.
A grand lobby with a chandelier, a staircase, and a central table with a floral arrangement.
A spacious lobby with a chandelier, seating area, and a central table with a vase of flowers.
A grand staircase with a curved design, leading to an upper floor.

16. Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
Frontenac
United States
Linda L
$130 nightly
$152 total
Oct 25 - Oct 26
Total with taxes and fees
Hilton St. Louis Frontenac
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.
A cozy living room with a large TV, a fireplace, a Christmas tree, and a view of the city.
A long dining table set with candles, glassware, and white flowers, suggesting a formal dining experience.
A bar area with a round table, ice-filled glasses, bottles of champagne, and decorative plants.

17. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
Clayton
United States
Marsha
$152 nightly
$179 total
Nov 1 - Nov 2
Total with taxes and fees
Le Méridien St. Louis Clayton
A modern dining area with round tables, orange chairs, and a decorative wall with pottery.
A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.
A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.
A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.

18. Marriott St. Louis Airport

Marriott St. Louis Airport
Edmundson
United States
Sha
$143 nightly
$172 total
Oct 30 - Oct 31
Total with taxes and fees
Marriott St. Louis Airport
A bar area with a central bar, multiple stools, and a chandelier.
A grand lobby with a large chandelier, a bar area, and classical architecture.
A grand lobby with a bar area, chandeliers, and seating.
A spacious lobby with a high ceiling, ornate chandeliers, and a seating area with sofas and armchairs.

19. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Downtown St. Louis
United States
Carol
$111 nightly
$132 total
Oct 30 - Oct 31
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
A spacious lobby with high arched ceilings, ornate columns, and a central fountain.
A multi-level hotel lobby with a grand staircase, a reception desk, and a seating area.
A restaurant with tables and chairs, large windows, and a view of the street.
A spacious lobby with high ceilings, ornate green and gold detailing, and a central bar area.

20. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
Downtown West
United States
Maryann
$163 nightly
$194 total
Oct 31 - Nov 1
Total with taxes and fees
St. Louis Union Station Hotel, Curio Collection by Hilton
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Des Peres.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
$375 nightly
$438 total
Oct 25 - Oct 26
Total with taxes and fees
Four Seasons Hotel St Louis
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
$579 nightly
$676 total
Nov 1 - Nov 2
Total with taxes and fees
9.2/10 Wonderful! (586 reviews)
The Ritz-Carlton, St. Louis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Des Peres

Just minutes from St. Louis, this charming suburb offers family-friendly recreation at Sugar Creek Park with playgrounds and walking trails. Spend an afternoon exploring the fascinating Museum of Transportation where vintage trains and automobiles bring America's transit history to life.

See all hotels in Des Peres
A museum exhibit with vintage vehicles including a 1934 Ford Phalet car and a fire truck.

Top Des Peres Hotel Reviews

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

8/10 Good
"Pretty cool hotel"
Gregory 2-night trip
Posted 15 hours ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Moonrise Hotel

Moonrise Hotel

10/10 Excellent
"Had the Vincent Price suite with a city view. Also loved the rooftop terrace."
Mark 1-night trip
Posted 19 hours ago
Moonrise Hotel
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

10/10 Excellent
"Easy check in"
Mark 1-night trip
Posted 1 day ago
Renaissance St. Louis Airport Hotel

Find out more about Des Peres

Des Peres Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Des Peres, St. Louis are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Des Peres 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Des Peres. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Des Peres, St. Louis, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Des Peres hotels offer everything your heart desires.

Frequently asked questions

What are the best 4-star hotels in Des Peres?
Hilton St. Louis Frontenac is a 4-star hotel in Des Peres that ranks highly among Expedia guests. Concierge services and limousine services are some of its many amenities. Travelers also love staying at Le Méridien St. Louis Clayton. From a swimming pool to a terrace, it comes with conveniences that cater to all aspects of your relaxation and enjoyment.
How much does it cost to stay in a 4-star hotel in Des Peres?
With Expedia's search and sort filters, bagging a great deal on a 4-star hotel in Des Peres just got easier. Start by entering your chosen arrival date and length of your break. Then sort the results by price and choose a property that best suits your style and budget.
  • Search for the lowest price from $438
What's the difference between 5-star and 4-star hotels in Des Peres?
If you decide to vacation at a 4-star hotel in Des Peres, you'll usually find loads of conveniences to ensure you're relaxed, such as a gym, restaurant and pool. You can enjoy high-quality service and deluxe accommodations. Choose a 5-star hotel and you'll have access to a few more perks — think concierge assistance, on-site spas and nightly turndown services. You'll most likely get additional amenities and exclusive services at a 5-star getaway, but both are terrific options for luxury travelers.

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