Title: The Best 5 Star Hotels in San Lorenzo from $218 | Expedia.com [San Lorenzo Travel Guide](https://expedia.com/Rome-San-Lorenzo.dx6145024)[Vacation Rentals in Rome](https://expedia.com/Rome-Vacation-Rentals.d179899.Travel-Guide-VacationRentals)[Flights to Rome](https://expedia.com/Cheap-Flights-To-Rome.d179899.Travel-Guide-Flights)[Things to do in Rome](https://expedia.com/Things-To-Do-In-Rome.d179899.Travel-Guide-Activities)[Car Rentals in San Lorenzo](https://expedia.com/Car-Rentals-In-San-Lorenzo.d6145024.Car-Rental-Guide)[San Lorenzo Vacations](https://expedia.com/San-Lorenzo.d6145024.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check availability on San Lorenzo 5 Star Hotels Tonight [Apr 8 - Apr 9](https://www.expedia.com/Hotel-Search?regionId=6145024&startDate=2026-04-08&endDate=2026-04-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 9 - Apr 10](https://www.expedia.com/Hotel-Search?regionId=6145024&startDate=2026-04-09&endDate=2026-04-10&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6145024&startDate=2026-04-10&endDate=2026-04-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=6145024&startDate=2026-04-17&endDate=2026-04-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for San Lorenzo 5-star hotels ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/351e1592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/372ab6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/7604df28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Navona) | Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/d3afe355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Raphaël – Relais & Châteaux [](https://www.expedia.com/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information) Rome City Centre 9.2/10 Wonderful (1,002 reviews) "Amazing location in the heart of the old city and the warmest most helpful staff ever!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David $382 nightly $443 total Apr 9 - Apr 10 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/9000000/8780000/8773800/8773754/ef4a7403.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/9000000/8780000/8773800/8773754/3c18cc5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, steam room, Turkish bath](https://images.trvl-media.com/lodging/9000000/8780000/8773800/8773754/834c56d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, steam room, Turkish bath](https://images.trvl-media.com/lodging/9000000/8780000/8773800/8773754/77c13126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### QC Grand Hotel Roma [](https://www.expedia.com/Rome-Hotels-QC-Termeroma-Spa-Resort.h8773754.Hotel-Information) Fiumicino 9.0/10 Wonderful (1,003 reviews) "Their restaurant offered excellent food and wine. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sylvia $302 nightly $343 total Apr 20 - Apr 21 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-QC-Termeroma-Spa-Resort.h8773754.Hotel-Information) ![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/08478e2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/ae094d19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/2e3cd109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/7c35417f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NH Collection Roma Palazzo Cinquecento [](https://www.expedia.com/Rome-Hotels-NH-Collection-Roma-Palazzo-Cinquecento.h12741260.Hotel-Information) Rome City Centre 9.0/10 Wonderful (1,001 reviews) "Great location and breakfast superb " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Stephen $367 nightly $427 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-NH-Collection-Roma-Palazzo-Cinquecento.h12741260.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/a3ebc34d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/57d1084d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Balcony | View from room](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/aadd1bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/e920a3f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Rome [](https://www.expedia.com/Rome-Hotels-W-Rome.h69386994.Hotel-Information) Rome City Centre 9.6/10 Exceptional (212 reviews) "We only stayed one night here before heading to the airport. The room was good, slept well and the staff very attentive. They had our taxi to the airport booked and ready the following morning." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ALUN HUW $492 nightly $565 total Apr 30 - May 1 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-W-Rome.h69386994.Hotel-Information) ![Mellini Suite | Premium bedding, memory foam beds, free minibar, in-room safe](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/1510dcb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mellini Suite | Premium bedding, memory foam beds, free minibar, in-room safe](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/w2330h3494x4y3-f53172b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/5a8f0c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/6e4e2007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Six Senses Rome [](https://www.expedia.com/Rome-Hotels-Six-Senses-Rome.h83216106.Hotel-Information) Rome City Centre 9.6/10 Exceptional (66 reviews) "Beautiful hotel in a perfect location. The interior design is stunning, the staff wonderful and the little touches such as the infinite complimentary drinks and healthy snacks makes the stay a true pleasure." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Benjamin $1,478 nightly $1,649 total Apr 15 - Apr 16 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Six-Senses-Rome.h83216106.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/1444f82e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/428251da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/w6377h4246x0y5-6e366eaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/w4148h2768x0y3-b519eb71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental Rome Ambasciatori Palace by IHG [](https://www.expedia.com/Rome-Hotels-InterContinental-Rome-Ambasciatori-Palace.h14529.Hotel-Information) Rome City Centre 9.6/10 Exceptional (178 reviews) "Great stay!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul $526 nightly $602 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-InterContinental-Rome-Ambasciatori-Palace.h14529.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/f57ce992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/3cf992c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/220db8f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/56010301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baglioni Hotel Regina - The Leading Hotels of the World [](https://www.expedia.com/Rome-Hotels-Baglioni-Hotel-Regina-The-Leading-Hotels-Of-The-World.h445130.Hotel-Information) Rome City Centre 9.0/10 Wonderful (528 reviews) "Rooms are clean, breakfast good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cem $573 nightly $653 total Apr 14 - Apr 15 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Baglioni-Hotel-Regina-The-Leading-Hotels-Of-The-World.h445130.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/e3a42652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/d35a8401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, cocktail bar, rooftop bar, lobby lounge](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/1dbc0992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/cbf73f06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aleph Rome Hotel Curio Collection by Hilton [](https://www.expedia.com/Rome-Hotels-Aleph-Rome-Hotel-Curio-Collection-By-Hilton.h905949.Hotel-Information) Rome City Centre 9.4/10 Exceptional (479 reviews) "Spacious room, helpful staff with tour websites for guests. Hotel was in a very quiet area but extremely convenient location to walk to all of the historical sites and shopping. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erika $532 nightly $608 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Aleph-Rome-Hotel-Curio-Collection-By-Hilton.h905949.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/a94432dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/d661ec21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/3b6a96a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/7e29f11d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Rome Villa Borghese [](https://www.expedia.com/Rome-Hotels-Sofitel-Rome-Villa-Borghese.h9234.Hotel-Information) Rome City Centre 9.2/10 Wonderful (980 reviews) "Professional staff, luxurious surroundings, excellent location, very nice accommodations - all in all a great experience. " ![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg) Daniel $477 nightly $548 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Sofitel-Rome-Villa-Borghese.h9234.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/ea2f10b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/4253247e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, Italian cuisine](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/c8d17c77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/dcca70cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World [](https://www.expedia.com/Rome-Hotels-Anantara-Palazzo-Naiadi-Rome-Hotel-A-Leading-Hotel-Of-The-World.h907346.Hotel-Information) Rome City Centre 9.2/10 Wonderful (1,000 reviews) "Clean rooms, close to everything, in a good safe area. Breakfast was one of the best highlights of the stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Morgan $771 nightly $871 total Apr 30 - May 1 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Anantara-Palazzo-Naiadi-Rome-Hotel-A-Leading-Hotel-Of-The-World.h907346.Hotel-Information) ![2 bars/lounges](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/2fccf7b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/c19872da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 38 per person)](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/6495ea6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Terrace, City View | Minibar, in-room safe, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/w3840h2557x0y0-11e439f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Collection Hotel, Roma Antica [](https://www.expedia.com/Rome-Hotels-Radisson-Collection-Hotel.h101129112.Hotel-Information) Rome City Centre 9.6/10 Exceptional (167 reviews) "Everything about the staff, location and food was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marco $416 nightly $481 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Radisson-Collection-Hotel.h101129112.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/w4000h2664x0y0-5e09c355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/82baf38c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/w4000h2664x0y0-eea1b5ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/c63db19c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Rome EDITION [](https://www.expedia.com/Rome-Hotels-The-Rome-Edition.h91518086.Hotel-Information) Rome City Centre 8.6/10 Excellent (39 reviews) "10/10 stay absolutely gorgeous hotel, great staff and handy location. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Katherine Haidee $714 nightly $809 total Apr 27 - Apr 28 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-The-Rome-Edition.h91518086.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/62c3e526.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 33 per person)](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/w2997h1997x0y0-e38173bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/b96175a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite | View from room](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/w2996h1998x0y0-c61cbfe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Palace Rome [](https://www.expedia.com/Rome-Hotels-Grand-Hotel-Palace.h663050.Hotel-Information) Rome City Centre 9.0/10 Wonderful (1,003 reviews) "Enjoyed our stay. Loved the outdoor patio in our room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patti $255 nightly $303 total Apr 27 - Apr 28 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Grand-Hotel-Palace.h663050.Hotel-Information) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/cd0177d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; alfresco dining](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/d359ea77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/c33634b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/892ffcec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Excelsior, Rome [](https://www.expedia.com/Rome-Hotels-The-Westin-Excelsior.h8002.Hotel-Information) Rome City Centre 8.2/10 Very Good (756 reviews) "Very clean, staff was very nice and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) len $525 nightly $601 total Apr 11 - Apr 12 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-The-Westin-Excelsior.h8002.Hotel-Information) ![Signature Suite, 1 King Bed (Planetarium Suite, Spa/Lounge Access) | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/6912f8ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/086a304a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite, 1 King Bed (Planetarium Suite, Spa/Lounge Access) | Living area | 42-inch LED TV with satellite channels, TV, DVD player](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/9f549232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/c1194e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rome Cavalieri, A Waldorf Astoria Hotel [](https://www.expedia.com/Rome-Hotels-Rome-Cavalieri.h14941.Hotel-Information) Trionfale 9.2/10 Wonderful (1,000 reviews) "Amazing stay, incredible staff , awesome spa" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kory $487 nightly $559 total Apr 15 - Apr 16 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Rome-Cavalieri.h14941.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/8d6ed6e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/4dd2cbea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite, 2 Bedrooms, Sauna, City View | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/0093daf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/b0d9d12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### U-Visionary Roma Hotel [](https://www.expedia.com/Rome-Hotels-U-Visionary-Roma-Hotel.h45167180.Hotel-Information) Rome City Centre 9.6/10 Exceptional (443 reviews) "Great location. Short walk to Trevi Fountain, Piazza de Spagna, Pantheon. Also great location for shopping, via del corso is a short walk. Great hotel and staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mahmut Burak $315 nightly $364 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-U-Visionary-Roma-Hotel.h45167180.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/d6369f38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/835db15d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/33904d48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/0c943386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Roma - The Leading Hotels of the World [](https://www.expedia.com/Rome-Hotels-Palazzo-Roma.h96484843.Hotel-Information) Rome City Centre 10/10 Exceptional (123 reviews) "Super nice hotel, great location and very friendly staff and manager. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ewing $637 nightly $724 total Apr 16 - Apr 17 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Palazzo-Roma.h96484843.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/fa75df6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/358cbffb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Suite, 1 King Bed, Ground Floor (Colosseum View) | View from room](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/4d277572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, bathrobes, slippers](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/f163216b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Manfredi – Small Luxury Hotels of the World [](https://www.expedia.com/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) Rome City Centre 9.0/10 Wonderful (653 reviews) "Absolutely loved this property. The location was perfect, room was spacious and comfortable. We loved ending our evenings in the court with a view of the Colosseum. Staff were friendly and helpful. Loved that it is a smaller property and felt cozy and like home. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittney $389 nightly $451 total Apr 9 - Apr 10 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/7de39039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room (Suite) | Premium bedding, down comforters, Select Comfort beds, minibar](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/w2997h1925x0y0-3b291246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/322c8698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/fe27d45d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Ripetta [](https://www.expedia.com/Rome-Hotels-Residenza-Di-Ripetta.h2912498.Hotel-Information) Rome City Centre 9.8/10 Exceptional (119 reviews) "A very nice boutique hotel in an excellent location, especially for shopping. The staff were extremely polite and helpful. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Hooman $689 nightly $781 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Residenza-Di-Ripetta.h2912498.Hotel-Information) ![Lunch, dinner served; local and international cuisine, alfresco dining ](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/263507da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/21d44ad0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/93b850c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 38.50 per person)](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/e71f6258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Splendide Royal - The Leading Hotels of the World [](https://www.expedia.com/Rome-Hotels-Hotel-Splendide-Royal-The-Leading-Hotels-Of-The-World.h581053.Hotel-Information) Rome City Centre 9.4/10 Exceptional (1,003 reviews) "Great location. Beautiful space. Super friendly staff. A true Roman experience!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elvis $555 nightly $634 total Apr 10 - Apr 11 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Hotel-Splendide-Royal-The-Leading-Hotels-Of-The-World.h581053.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-San-Lorenzo-Rome-Hotels.s50-n6145024-0.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-San-Lorenzo-Rome-Hotels.s50-n6145024-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in San Lorenzo. ![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/1c2ed679_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Quirinale Via Nazionale 7 Rome RM $206 nightly $244 total Apr 12 - Apr 13 Total with taxes and fees 8.6/10 Excellent! (1,927 reviews) [](https://expedia.com/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![Hilton Garden Inn Rome Airport](https://images.trvl-media.com/lodging/2000000/1590000/1587200/1587154/78454e47_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Garden Inn Rome Airport Via Vittorio Bragadin 2 Fiumicino RM $188 nightly $218 total Apr 20 - Apr 21 Total with taxes and fees 8.2/10 Very Good! (3,757 reviews) [](https://expedia.com/Rome-Hotels-Hilton-Garden-Inn-Rome-Airport.h1587154.Hotel-Information) ![Hilton Rome Airport](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/68ada719_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Rome Airport Via Arturo Ferrarin 2 Fiumicino RM $252 nightly $289 total Apr 20 - Apr 21 Total with taxes and fees 8.2/10 Very Good! (3,224 reviews) [](https://expedia.com/Rome-Hotels-Hilton-Rome-Airport.h564180.Hotel-Information) Still don't see what you're looking for? [See all properties in San Lorenzo.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F9%2F2026&endDate=4%2F10%2F2026®ionId=6145024&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F9%2F2026&endDate=4%2F10%2F2026®ionId=6145024&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F9%2F2026&endDate=4%2F10%2F2026®ionId=6145024&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F9%2F2026&endDate=4%2F10%2F2026®ionId=6145024&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F9%2F2026&endDate=4%2F10%2F2026®ionId=6145024&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F9%2F2026&endDate=4%2F10%2F2026®ionId=6145024&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top San Lorenzo Hotel Reviews ## Find out more about San Lorenzo Ready for an incredible adventure? Add further pleasure on your next trip to San Lorenzo by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made San Lorenzo so popular in the last year. There's no reason to delay a getaway to San Lorenzo any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Our 5-star hotels in San Lorenzo are the perfect places to relax in when you really need to escape. You deserve the great vacation you're dreaming about. ### Book the Best San Lorenzo 5-Star Hotels You'll have a fantastic time at one of these 5-star hotels. High-end restaurants, exceptional customer care, and fabulous spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. What creature comforts do you want in your lodging? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A body scrub that will leave you feeling like a million bucks? Butler services? Whatever it is your heart desires, you're bound to find it here. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs. You won't sleep and order room service the entire time, though. We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in San Lorenzo are waiting for you to relax after a busy day. ### Your Getaway Starts Today The results are in, and San Lorenzo 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. 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