Title: The Best 5 Star Hotels in San Lorenzo from $193 | Expedia.com

[San Lorenzo Travel Guide](https://expedia.com/Rome-San-Lorenzo.dx6145024)[Vacation Rentals in Rome](https://expedia.com/Rome-Vacation-Rentals.d179899.Travel-Guide-VacationRentals)[Flights to Rome](https://expedia.com/Cheap-Flights-To-Rome.d179899.Travel-Guide-Flights)[Things to do in Rome](https://expedia.com/Things-To-Do-In-Rome.d179899.Travel-Guide-Activities)[Car Rentals in San Lorenzo](https://expedia.com/Car-Rentals-In-San-Lorenzo.d6145024.Car-Rental-Guide)[San Lorenzo Vacations](https://expedia.com/San-Lorenzo.d6145024.Destination-Travel-Guides)

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## Check availability on San Lorenzo 5 Star Hotels

Tonight

[Mar 21 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6145024&startDate=2026-03-21&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 22 - Mar 23](https://www.expedia.com/Hotel-Search?regionId=6145024&startDate=2026-03-22&endDate=2026-03-23&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6145024&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6145024&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for San Lorenzo 5-star hotels

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/351e1592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/7604df28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/c16a8c43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/372ab6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Raphaël – Relais & Châteaux

[](https://www.expedia.com/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information)

Rome City Centre

9.2/10

Wonderful

(1,000 reviews)

"Excellent staff and service. Property is in a great location. Walking distance to many of the famous sites and landmarks, street restaurants,etc. would stay there again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gary

$252 nightly

$301 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information)

![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/08478e2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/e9e1e7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/7c35417f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/2e3cd109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### NH Collection Roma Palazzo Cinquecento

[](https://www.expedia.com/Rome-Hotels-NH-Collection-Roma-Palazzo-Cinquecento.h12741260.Hotel-Information)

Rome City Centre

9.0/10

Wonderful

(1,002 reviews)

"Great location and breakfast superb "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Stephen

$364 nightly

$424 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-NH-Collection-Roma-Palazzo-Cinquecento.h12741260.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/a3ebc34d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/d2975d19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/e920a3f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio, 1 King Bed, Balcony | View from room](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/aadd1bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### W Rome

[](https://www.expedia.com/Rome-Hotels-W-Rome.h69386994.Hotel-Information)

Rome City Centre

9.6/10

Exceptional

(210 reviews)

"Amazing hotel, wonderful staff, convenience "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Anna

$589 nightly

$671 total

Mar 25 - Mar 26

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-W-Rome.h69386994.Hotel-Information)

![Mellini Suite | Premium bedding, memory foam beds, free minibar, in-room safe](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/1510dcb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/5a8f0c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/6e4e2007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Mellini Suite | Premium bedding, memory foam beds, free minibar, in-room safe](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/w2330h3494x4y3-f53172b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Six Senses Rome

[](https://www.expedia.com/Rome-Hotels-Six-Senses-Rome.h83216106.Hotel-Information)

Rome City Centre

9.6/10

Exceptional

(65 reviews)

"Beautiful hotel in a perfect location. The interior design is stunning, the staff wonderful and the little touches such as the infinite complimentary drinks and healthy snacks makes the stay a true pleasure."

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Benjamin

$1,338 nightly

$1,495 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Six-Senses-Rome.h83216106.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/1444f82e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/f2e5cacc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/428251da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/w4148h2768x0y3-b519eb71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### InterContinental Rome Ambasciatori Palace by IHG

[](https://www.expedia.com/Rome-Hotels-InterContinental-Rome-Ambasciatori-Palace.h14529.Hotel-Information)

Rome City Centre

9.6/10

Exceptional

(177 reviews)

"Great stay!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

$505 nightly

$579 total

Apr 14 - Apr 15

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-InterContinental-Rome-Ambasciatori-Palace.h14529.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/f57ce992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Balcony view](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/220db8f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/3cf992c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/56010301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baglioni Hotel Regina - The Leading Hotels of the World

[](https://www.expedia.com/Rome-Hotels-Baglioni-Hotel-Regina-The-Leading-Hotels-Of-The-World.h445130.Hotel-Information)

Rome City Centre

9.0/10

Wonderful

(522 reviews)

"Rooms are clean, breakfast good"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

cem

$554 nightly

$632 total

Mar 23 - Mar 24

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Baglioni-Hotel-Regina-The-Leading-Hotels-Of-The-World.h445130.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/e3a42652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Terrace (Prestige) | Terrace/patio](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/16daf83b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/d35a8401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/cbf73f06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aleph Rome Hotel Curio Collection by Hilton

[](https://www.expedia.com/Rome-Hotels-Aleph-Rome-Hotel-Curio-Collection-By-Hilton.h905949.Hotel-Information)

Rome City Centre

9.4/10

Exceptional

(478 reviews)

"Spacious room, helpful staff with tour websites for guests. Hotel was in a very quiet area but extremely convenient location to walk to all of the historical sites and shopping. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erika

$465 nightly

$535 total

Mar 30 - Mar 31

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Aleph-Rome-Hotel-Curio-Collection-By-Hilton.h905949.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/3d3ff7e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/3b6a96a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/d661ec21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/2238bde7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sofitel Rome Villa Borghese

[](https://www.expedia.com/Rome-Hotels-Sofitel-Rome-Villa-Borghese.h9234.Hotel-Information)

Rome City Centre

9.2/10

Wonderful

(979 reviews)

"Professional staff, luxurious surroundings, excellent location, very nice accommodations - all in all a great experience. "

![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg)

Daniel

$431 nightly

$498 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Sofitel-Rome-Villa-Borghese.h9234.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/ea2f10b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/4253247e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/3ece677b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/dcca70cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

[](https://www.expedia.com/Rome-Hotels-Anantara-Palazzo-Naiadi-Rome-Hotel-A-Leading-Hotel-Of-The-World.h907346.Hotel-Information)

Rome City Centre

9.2/10

Wonderful

(1,000 reviews)

"incredible, no hotel compares to it. everything was perfect "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sana

$738 nightly

$835 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Anantara-Palazzo-Naiadi-Rome-Hotel-A-Leading-Hotel-Of-The-World.h907346.Hotel-Information)

![2 bars/lounges](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/2fccf7b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (EUR 38 per person)](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/6495ea6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/4bce46fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, Terrace, City View | Minibar, in-room safe, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/w3840h2557x0y0-11e439f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Radisson Collection Hotel, Roma Antica

[](https://www.expedia.com/Rome-Hotels-Radisson-Collection-Hotel.h101129112.Hotel-Information)

Rome City Centre

9.6/10

Exceptional

(164 reviews)

"Great staff clean rooms "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anthony

$407 nightly

$471 total

Mar 25 - Mar 26

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Radisson-Collection-Hotel.h101129112.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/w4000h2664x0y0-5e09c355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/w4000h2664x0y0-eea1b5ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/c63db19c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, cocktail bar, cocktail bar](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/f28f4bac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Rome EDITION

[](https://www.expedia.com/Rome-Hotels-The-Rome-Edition.h91518086.Hotel-Information)

Rome City Centre

8.6/10

Excellent

(39 reviews)

"10/10 stay absolutely gorgeous hotel, great staff and handy location. "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Katherine Haidee

$671 nightly

$761 total

Mar 24 - Mar 25

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-The-Rome-Edition.h91518086.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/62c3e526.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (EUR 33 per person)](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/w2997h1997x0y0-e38173bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Room | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/ff430e96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/b96175a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Palace Rome

[](https://www.expedia.com/Rome-Hotels-Grand-Hotel-Palace.h663050.Hotel-Information)

Rome City Centre

9.0/10

Wonderful

(1,002 reviews)

"Enjoyed our stay. Loved the outdoor patio in our room. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Patti

$231 nightly

$278 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Grand-Hotel-Palace.h663050.Hotel-Information)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/cd0177d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/c33634b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/892ffcec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; alfresco dining](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/d359ea77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Westin Excelsior, Rome

[](https://www.expedia.com/Rome-Hotels-The-Westin-Excelsior.h8002.Hotel-Information)

Rome City Centre

8.2/10

Very Good

(753 reviews)

"Very clean, staff was very nice and helpful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

len

$437 nightly

$504 total

Apr 13 - Apr 14

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-The-Westin-Excelsior.h8002.Hotel-Information)

![Signature Suite, 1 King Bed (Planetarium Suite, Spa/Lounge Access) | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/6912f8ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, 3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/a94e4883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/c1194e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/086a304a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Rome Cavalieri, A Waldorf Astoria Hotel

[](https://www.expedia.com/Rome-Hotels-Rome-Cavalieri.h14941.Hotel-Information)

Trionfale

9.2/10

Wonderful

(1,000 reviews)

"Amazing stay, incredible staff , awesome spa"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kory

$346 nightly

$404 total

Mar 25 - Mar 26

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Rome-Cavalieri.h14941.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/8d6ed6e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/4dd2cbea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/b0d9d12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Open Suite | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/43fc0905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### U-Visionary Roma Hotel

[](https://www.expedia.com/Rome-Hotels-U-Visionary-Roma-Hotel.h45167180.Hotel-Information)

Rome City Centre

9.6/10

Exceptional

(439 reviews)

"Lovely staff, beautiful hotel, nice rooms and a great breakfast buffet. "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Jessica

$229 nightly

$270 total

Mar 26 - Mar 27

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-U-Visionary-Roma-Hotel.h45167180.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/d6369f38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/835db15d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/0c943386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite | Living area | 50-inch flat-screen TV with satellite channels](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/389a42b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palazzo Roma - The Leading Hotels of the World

[](https://www.expedia.com/Rome-Hotels-Palazzo-Roma.h96484843.Hotel-Information)

Rome City Centre

9.8/10

Exceptional

(120 reviews)

"Super nice hotel, great location and very friendly staff and manager. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ewing

$469 nightly

$539 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Palazzo-Roma.h96484843.Hotel-Information)

![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/7d6d9ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/358cbffb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Suite, 1 King Bed, Ground Floor (Colosseum View) | View from room](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/4d277572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free toiletries, hair dryer, bathrobes, slippers](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/f163216b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palazzo Manfredi – Small Luxury Hotels of the World

[](https://www.expedia.com/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information)

Rome City Centre

9.0/10

Wonderful

(651 reviews)

"Absolutely loved this property. The location was perfect, room was spacious and comfortable. We loved ending our evenings in the court with a view of the Colosseum. Staff were friendly and helpful. Loved that it is a smaller property and felt cozy and like home. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brittney

$411 nightly

$476 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/7de39039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/0e5dc5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/fe27d45d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Room (Suite) | Premium bedding, down comforters, Select Comfort beds, minibar](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/w2997h1925x0y0-3b291246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palazzo Ripetta

[](https://www.expedia.com/Rome-Hotels-Residenza-Di-Ripetta.h2912498.Hotel-Information)

Rome City Centre

9.8/10

Exceptional

(115 reviews)

"Nice property, great staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Natale

$550 nightly

$628 total

Mar 31 - Apr 1

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Residenza-Di-Ripetta.h2912498.Hotel-Information)

![Lunch, dinner served; local and international cuisine, alfresco dining ](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/263507da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (EUR 38.50 per person)](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/e71f6258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/94dbae85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/93b850c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Splendide Royal - The Leading Hotels of the World

[](https://www.expedia.com/Rome-Hotels-Hotel-Splendide-Royal-The-Leading-Hotels-Of-The-World.h581053.Hotel-Information)

Rome City Centre

9.4/10

Exceptional

(1,001 reviews)

"Great location. Beautiful space. Super friendly staff. A true Roman experience!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elvis

$520 nightly

$595 total

Mar 26 - Mar 27

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Hotel-Splendide-Royal-The-Leading-Hotels-Of-The-World.h581053.Hotel-Information)

![Lunch and dinner served, international cuisine](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/9c429475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/58d8f9b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/eacf5f04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lunch and dinner served, international cuisine](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/c9448112.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sina Bernini Bristol, Autograph Collection

[](https://www.expedia.com/Rome-Hotels-Sina-Bernini-Bristol.h445235.Hotel-Information)

Rome City Centre

8.2/10

Very Good

(547 reviews)

"Amazing staff service and beautiful room "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Samantha

$491 nightly

$564 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/Rome-Hotels-Sina-Bernini-Bristol.h445235.Hotel-Information)

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in San Lorenzo.

![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/1c2ed679_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Quirinale

Via Nazionale 7 Rome RM

$199 nightly

$236 total

Apr 6 - Apr 7

Total with taxes and fees

8.6/10 Excellent! (1,941 reviews)

[](https://expedia.com/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information)

![Hilton Garden Inn Rome Airport](https://images.trvl-media.com/lodging/2000000/1590000/1587200/1587154/78454e47_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hilton Garden Inn Rome Airport

Via Vittorio Bragadin 2 Fiumicino RM

$165 nightly

$193 total

Mar 30 - Mar 31

Total with taxes and fees

8.2/10 Very Good! (3,735 reviews)

[](https://expedia.com/Rome-Hotels-Hilton-Garden-Inn-Rome-Airport.h1587154.Hotel-Information)

![Hilton Rome Airport](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/ec19f7f6_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hilton Rome Airport

Via Arturo Ferrarin 2 Fiumicino RM

$256 nightly

$293 total

Apr 20 - Apr 21

Total with taxes and fees

8.2/10 Very Good! (3,216 reviews)

[](https://expedia.com/Rome-Hotels-Hilton-Rome-Airport.h564180.Hotel-Information)

Still don't see what you're looking for?

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[Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&regionId=6145024&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&regionId=6145024&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&regionId=6145024&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&regionId=6145024&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&regionId=6145024&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Top San Lorenzo Hotel Reviews

## Find out more about San Lorenzo

Ready for an incredible adventure? Add further pleasure on your next trip to San Lorenzo by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made San Lorenzo so popular in the last year. There's no reason to delay a getaway to San Lorenzo any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Our 5-star hotels in San Lorenzo are the perfect places to relax in when you really need to escape. You deserve the great vacation you're dreaming about.

### Book the Best San Lorenzo 5-Star Hotels

You'll have a fantastic time at one of these 5-star hotels. High-end restaurants, exceptional customer care, and fabulous spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. What creature comforts do you want in your lodging? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A body scrub that will leave you feeling like a million bucks? Butler services? Whatever it is your heart desires, you're bound to find it here. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs. 

You won't sleep and order room service the entire time, though. We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in San Lorenzo are waiting for you to relax after a busy day.

### Your Getaway Starts Today

The results are in, and San Lorenzo 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Decide on one of our San Lorenzo 5-star hotels today and decompress in the lap of luxury tomorrow.

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