Title: The Best 5 Star Hotels in San Lorenzo from $191 | Expedia.com [San Lorenzo Travel Guide](https://expedia.com/Rome-San-Lorenzo.dx6145024)[Vacation Rentals in Rome](https://expedia.com/Rome-Vacation-Rentals.d179899.Travel-Guide-VacationRentals)[Flights to Rome](https://expedia.com/Cheap-Flights-To-Rome.d179899.Travel-Guide-Flights)[Things to do in Rome](https://expedia.com/Things-To-Do-In-Rome.d179899.Travel-Guide-Activities)[Car Rentals in San Lorenzo](https://expedia.com/Car-Rentals-In-San-Lorenzo.d6145024.Car-Rental-Guide)[San Lorenzo Vacations](https://expedia.com/San-Lorenzo.d6145024.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on San Lorenzo 5 Star Hotels Tonight [Mar 16 - Mar 17](https://www.expedia.com/Hotel-Search?regionId=6145024&startDate=2026-03-16&endDate=2026-03-17&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 17 - Mar 18](https://www.expedia.com/Hotel-Search?regionId=6145024&startDate=2026-03-17&endDate=2026-03-18&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6145024&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6145024&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for San Lorenzo 5-star hotels ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/351e1592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/c16a8c43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/7604df28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/372ab6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Raphaël – Relais & Châteaux [](https://www.expedia.com/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information) Rome City Centre 9.2/10 Wonderful (1,001 reviews) "Excellent staff and service. Property is in a great location. Walking distance to many of the famous sites and landmarks, street restaurants,etc. would stay there again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary $291 nightly $343 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information) ![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/08478e2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/e9e1e7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/2e3cd109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12750000/12741300/12741260/ae094d19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NH Collection Roma Palazzo Cinquecento [](https://www.expedia.com/Rome-Hotels-NH-Collection-Roma-Palazzo-Cinquecento.h12741260.Hotel-Information) Rome City Centre 9.0/10 Wonderful (1,004 reviews) "Very close to Termini railway station. So easy to go to the airport. Very nice breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sergey $359 nightly $418 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-NH-Collection-Roma-Palazzo-Cinquecento.h12741260.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/a3ebc34d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/57d1084d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Balcony | View from room](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/aadd1bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/70000000/69390000/69387000/69386994/e920a3f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Rome [](https://www.expedia.com/Rome-Hotels-W-Rome.h69386994.Hotel-Information) Rome City Centre 9.6/10 Exceptional (210 reviews) "Amazing hotel, wonderful staff, convenience " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Anna $581 nightly $662 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-W-Rome.h69386994.Hotel-Information) ![Mellini Suite | Premium bedding, memory foam beds, free minibar, in-room safe](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/1510dcb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/6e4e2007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mellini Suite | Premium bedding, memory foam beds, free minibar, in-room safe](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/w2330h3494x4y3-f53172b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83220000/83216200/83216106/da28f9f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Six Senses Rome [](https://www.expedia.com/Rome-Hotels-Six-Senses-Rome.h83216106.Hotel-Information) Rome City Centre 9.6/10 Exceptional (65 reviews) "Beautiful hotel in a perfect location. The interior design is stunning, the staff wonderful and the little touches such as the infinite complimentary drinks and healthy snacks makes the stay a true pleasure." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Benjamin $1,320 nightly $1,475 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Six-Senses-Rome.h83216106.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/1444f82e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/w4148h2768x0y3-b519eb71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/f2e5cacc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14600/14529/w6377h4246x0y5-6e366eaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental Rome Ambasciatori Palace by IHG [](https://www.expedia.com/Rome-Hotels-InterContinental-Rome-Ambasciatori-Palace.h14529.Hotel-Information) Rome City Centre 9.6/10 Exceptional (176 reviews) "Great stay!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul $582 nightly $663 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-InterContinental-Rome-Ambasciatori-Palace.h14529.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/f57ce992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/3cf992c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/eeec3cd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/220db8f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baglioni Hotel Regina - The Leading Hotels of the World [](https://www.expedia.com/Rome-Hotels-Baglioni-Hotel-Regina-The-Leading-Hotels-Of-The-World.h445130.Hotel-Information) Rome City Centre 9.0/10 Wonderful (521 reviews) "Rooms are clean, breakfast good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cem $546 nightly $624 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Baglioni-Hotel-Regina-The-Leading-Hotels-Of-The-World.h445130.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/e3a42652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Terrace (Prestige) | Terrace/patio](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/16daf83b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/cbf73f06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, cocktail bar, rooftop bar, lobby lounge](https://images.trvl-media.com/lodging/1000000/910000/906000/905949/1dbc0992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aleph Rome Hotel Curio Collection by Hilton [](https://www.expedia.com/Rome-Hotels-Aleph-Rome-Hotel-Curio-Collection-By-Hilton.h905949.Hotel-Information) Rome City Centre 9.4/10 Exceptional (478 reviews) "Spacious room, helpful staff with tour websites for guests. Hotel was in a very quiet area but extremely convenient location to walk to all of the historical sites and shopping. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erika $442 nightly $509 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Aleph-Rome-Hotel-Curio-Collection-By-Hilton.h905949.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/3d3ff7e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/d661ec21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/805a597f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9300/9234/3b6a96a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Rome Villa Borghese [](https://www.expedia.com/Rome-Hotels-Sofitel-Rome-Villa-Borghese.h9234.Hotel-Information) Rome City Centre 9.2/10 Wonderful (978 reviews) "Professional staff, luxurious surroundings, excellent location, very nice accommodations - all in all a great experience. " ![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg) Daniel $400 nightly $462 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Sofitel-Rome-Villa-Borghese.h9234.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/ea2f10b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/3ece677b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, Italian cuisine](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/c8d17c77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/910000/907400/907346/4253247e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World [](https://www.expedia.com/Rome-Hotels-Anantara-Palazzo-Naiadi-Rome-Hotel-A-Leading-Hotel-Of-The-World.h907346.Hotel-Information) Rome City Centre 9.2/10 Wonderful (1,000 reviews) "incredible, no hotel compares to it. everything was perfect " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sana $689 nightly $781 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Anantara-Palazzo-Naiadi-Rome-Hotel-A-Leading-Hotel-Of-The-World.h907346.Hotel-Information) ![2 bars/lounges](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/2fccf7b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 38 per person)](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/6495ea6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Terrace, City View | Minibar, in-room safe, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/w3840h2557x0y0-11e439f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/102000000/101130000/101129200/101129112/c19872da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Collection Hotel, Roma Antica [](https://www.expedia.com/Rome-Hotels-Radisson-Collection-Hotel.h101129112.Hotel-Information) Rome City Centre 9.6/10 Exceptional (163 reviews) "Great staff clean rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony $365 nightly $425 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Radisson-Collection-Hotel.h101129112.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/w4000h2664x0y0-5e09c355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/w4000h2664x0y0-eea1b5ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, cocktail bar](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/62da7cbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, cocktail bar](https://images.trvl-media.com/lodging/92000000/91520000/91518100/91518086/f28f4bac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Rome EDITION [](https://www.expedia.com/Rome-Hotels-The-Rome-Edition.h91518086.Hotel-Information) Rome City Centre 8.6/10 Excellent (39 reviews) "10/10 stay absolutely gorgeous hotel, great staff and handy location. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Katherine Haidee $754 nightly $852 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-The-Rome-Edition.h91518086.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/62c3e526.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/ff430e96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/b96175a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/663100/663050/d8e21c6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Palace Rome [](https://www.expedia.com/Rome-Hotels-Grand-Hotel-Palace.h663050.Hotel-Information) Rome City Centre 9.0/10 Wonderful (1,000 reviews) "Great service, good food, clean and polite stadf" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vinit $235 nightly $282 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Grand-Hotel-Palace.h663050.Hotel-Information) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/cd0177d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room, Turkish bath, body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/18ffa144.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; alfresco dining](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/d359ea77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8002/892ffcec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Excelsior, Rome [](https://www.expedia.com/Rome-Hotels-The-Westin-Excelsior.h8002.Hotel-Information) Rome City Centre 8.2/10 Very Good (752 reviews) "Very clean, staff was very nice and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) len $432 nightly $498 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-The-Westin-Excelsior.h8002.Hotel-Information) ![Signature Suite, 1 King Bed (Planetarium Suite, Spa/Lounge Access) | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/6912f8ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/c1194e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, 3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/a94e4883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/1000000/20000/15000/14941/086a304a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rome Cavalieri, A Waldorf Astoria Hotel [](https://www.expedia.com/Rome-Hotels-Rome-Cavalieri.h14941.Hotel-Information) Trionfale 9.2/10 Wonderful (1,004 reviews) "Everything was amazing. The food, the size of the rooms, the location, the amenities - the pool, wonderful! " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Athena $309 nightly $362 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Rome-Cavalieri.h14941.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/8d6ed6e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite, 2 Bedrooms, Sauna, City View | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/0093daf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Open Suite | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/43fc0905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/46000000/45170000/45167200/45167180/4dd2cbea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### U-Visionary Roma Hotel [](https://www.expedia.com/Rome-Hotels-U-Visionary-Roma-Hotel.h45167180.Hotel-Information) Rome City Centre 9.6/10 Exceptional (439 reviews) "Lovely staff, beautiful hotel, nice rooms and a great breakfast buffet. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Jessica $251 nightly $294 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-U-Visionary-Roma-Hotel.h45167180.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/d6369f38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/835db15d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/0c943386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite | Living area | 50-inch flat-screen TV with satellite channels](https://images.trvl-media.com/lodging/97000000/96490000/96484900/96484843/389a42b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Roma - The Leading Hotels of the World [](https://www.expedia.com/Rome-Hotels-Palazzo-Roma.h96484843.Hotel-Information) Rome City Centre 10/10 Exceptional (119 reviews) "Super nice hotel, great location and very friendly staff and manager. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ewing $435 nightly $501 total Mar 18 - Mar 19 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Palazzo-Roma.h96484843.Hotel-Information) ![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/7d6d9ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/16472e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, bathrobes, slippers](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/f163216b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Suite, 1 King Bed, Ground Floor (Colosseum View) | View from room](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/4d277572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Manfredi – Small Luxury Hotels of the World [](https://www.expedia.com/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) Rome City Centre 9.0/10 Wonderful (650 reviews) "Absolutely loved this property. The location was perfect, room was spacious and comfortable. We loved ending our evenings in the court with a view of the Colosseum. Staff were friendly and helpful. Loved that it is a smaller property and felt cozy and like home. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittney $380 nightly $441 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/7de39039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room (Suite) | Premium bedding, down comforters, Select Comfort beds, minibar](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/w2997h1925x0y0-3b291246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/322c8698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/3000000/2920000/2912500/2912498/fe27d45d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Ripetta [](https://www.expedia.com/Rome-Hotels-Residenza-Di-Ripetta.h2912498.Hotel-Information) Rome City Centre 9.8/10 Exceptional (114 reviews) "Nice property, great staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Natale $518 nightly $593 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Residenza-Di-Ripetta.h2912498.Hotel-Information) ![Lunch, dinner served; local and international cuisine, alfresco dining ](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/263507da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/93b850c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/94dbae85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/21d44ad0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Splendide Royal - The Leading Hotels of the World [](https://www.expedia.com/Rome-Hotels-Hotel-Splendide-Royal-The-Leading-Hotels-Of-The-World.h581053.Hotel-Information) Rome City Centre 9.4/10 Exceptional (1,000 reviews) "Very professional and nice staff. Everything was excellent and close to everywhere " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fatih $473 nightly $543 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Hotel-Splendide-Royal-The-Leading-Hotels-Of-The-World.h581053.Hotel-Information) ![Lunch and dinner served, international cuisine](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/9c429475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/eacf5f04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/58d8f9b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, international cuisine](https://images.trvl-media.com/lodging/1000000/450000/445300/445235/c9448112.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sina Bernini Bristol, Autograph Collection [](https://www.expedia.com/Rome-Hotels-Sina-Bernini-Bristol.h445235.Hotel-Information) Rome City Centre 8.2/10 Very Good (546 reviews) "Amazing staff service and beautiful room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha $475 nightly $546 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Sina-Bernini-Bristol.h445235.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-San-Lorenzo-Rome-Hotels.s50-n6145024-0.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-San-Lorenzo-Rome-Hotels.s50-n6145024-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in San Lorenzo. ![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/1c2ed679_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Quirinale Via Nazionale 7 Rome RM $191 nightly $227 total Mar 16 - Mar 17 Total with taxes and fees 8.6/10 Excellent! (1,951 reviews) [](https://expedia.com/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![Hilton Garden Inn Rome Airport](https://images.trvl-media.com/lodging/2000000/1590000/1587200/1587154/78454e47_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Garden Inn Rome Airport Via Vittorio Bragadin 2 Fiumicino RM $163 nightly $191 total Mar 30 - Mar 31 Total with taxes and fees 8.2/10 Very Good! (3,723 reviews) [](https://expedia.com/Rome-Hotels-Hilton-Garden-Inn-Rome-Airport.h1587154.Hotel-Information) ![Hilton Rome Airport](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/ec19f7f6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Rome Airport Via Arturo Ferrarin 2 Fiumicino RM $236 nightly $271 total Mar 18 - Mar 19 Total with taxes and fees 8.2/10 Very Good! (3,211 reviews) [](https://expedia.com/Rome-Hotels-Hilton-Rome-Airport.h564180.Hotel-Information) Still don't see what you're looking for? [See all properties in San Lorenzo.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F16%2F2026&endDate=3%2F17%2F2026®ionId=6145024&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F16%2F2026&endDate=3%2F17%2F2026®ionId=6145024&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F16%2F2026&endDate=3%2F17%2F2026®ionId=6145024&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F16%2F2026&endDate=3%2F17%2F2026®ionId=6145024&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F16%2F2026&endDate=3%2F17%2F2026®ionId=6145024&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F16%2F2026&endDate=3%2F17%2F2026®ionId=6145024&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top San Lorenzo Hotel Reviews ## Find out more about San Lorenzo Ready for an incredible adventure? Add further pleasure on your next trip to San Lorenzo by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made San Lorenzo so popular in the last year. There's no reason to delay a getaway to San Lorenzo any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Our 5-star hotels in San Lorenzo are the perfect places to relax in when you really need to escape. You deserve the great vacation you're dreaming about. ### Book the Best San Lorenzo 5-Star Hotels You'll have a fantastic time at one of these 5-star hotels. High-end restaurants, exceptional customer care, and fabulous spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. What creature comforts do you want in your lodging? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A body scrub that will leave you feeling like a million bucks? Butler services? Whatever it is your heart desires, you're bound to find it here. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs. You won't sleep and order room service the entire time, though. We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in San Lorenzo are waiting for you to relax after a busy day. ### Your Getaway Starts Today The results are in, and San Lorenzo 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. 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