De Soto Vacation Rentals

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Our top choices for De Soto vacation rentals

Vacation Home in West Des Moines

9.8 out of 10, Exceptional, (68)
"Used this place for a rehearsal dinner and getting ready for the wedding and it worked out perfect"
United States
Lane B.
$647 nightly
The price is $725
Dec 10 - Dec 11
Total with taxes and fees
AMAZING & A PARTY BARN… HOT TUB, PL TBl, PNG PNG, & ARCADE! ACCESS TO POOLS!

Vacation Home in Waukee

9.8 out of 10, Exceptional, (68)
"The place was perfect for our larger group of friends to have a reunion at. Matched the pictures and had plenty to keep us entertained for the weekend. Great place to stay! "
United States
Ben L.
$439 nightly
The price is $492
Dec 10 - Dec 11
Total with taxes and fees
LUXURY GETAWAY! ARCADE, POOL TBL, PING PONG, HOT TUB, DECK! ACCESS TO POOLS!

Vacation Home in Woodland Heights

9.4 out of 10, Exceptional, (63)
"Thanks so much! We enjoyed the stay with our family"
United States
Julia C.
$455 nightly
The price is $510
Jan 5 - Jan 6, 2026
Total with taxes and fees
SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!

Vacation Home in Urbandale

9.4 out of 10, Exceptional, (73)
"Excellent property with a ton of amenities! Everything we needed was there and easy to find."
United States
Jacob F.
$328 nightly
The price is $367
Dec 10 - Dec 11
Total with taxes and fees
NEW REMODEL! ARCADE GAMES, PNG PNG, SKEE BALL, ACCESS TO POOL. WE HAVE IT ALL!

Vacation Home in Winterset

10.0 out of 10, Exceptional, (3)
"This was an amazing house to rent. It was super cute and clean. It was walkable to the downtown. We stayed during the Bridges of Madison County festival and we were able to walk there. The host was great at communicating. I would stay here again and would recommend it to anyone visiting Winterset. "
United States
Melinda E.
The Little Brick House - Walkable to the Square Dining & Shopping

Vacation Home in Waveland Park

9.8 out of 10, Exceptional, (49)
"Great place to stay"
United States
Ben C.
2-bedroom vacation home just 3 minutes drive to Drake University

Vacation Home in West Des Moines

9.4 out of 10, Exceptional, (180)
"Lovely place to stay! Well cared for and lots of amenities. Thank you for such a charming place to rest while we were visiting Des Moines!"
United States
Christine H.
Walnut Place a Charming Home in Historic Valley Junction area of West Des Moines

Vacation Home in Windsor Heights

2.0 star property
10.0 out of 10, Exceptional, (12)
"It was the perfect house for a larger group. The house had a little of everything we needed, and we loved all the details they thought of. I would highly recommend"
United States
Jennifer H.
$447 nightly
The price is $501
Dec 10 - Dec 11
Total with taxes and fees
The Love Shack | Spacious Family Getaway • 5BR/3BA • 10 Mins to Downtown

Vacation Home in Drake

10.0 out of 10, Exceptional, (54)
"This home and hosts are fantastic! Very detail oriented owners. Good quality furnishings that enhanced the stay (I.e. linens, beds)"
United States
Randy and Nicole G.
$735 nightly
The price is $823
Dec 10 - Dec 11
Total with taxes and fees
Beautiful remodeled historic Drake Univ home minutes from downtown and all metro

Vacation Home in Beaverdale

9.4 out of 10, Exceptional, (29)
"This location had the space, comfort and amenities to make our stay enjoyable. "
United States
Mark and Karen S.
Charming Beaverdale 4BR/2BA in central DSM - Safe & Cozy

Vacation Home in Dallas Center

10.0 out of 10, Exceptional, (18)
"We loved the nearby Amish grocery store."
United States
Teresa
$171 nightly
The price is $180
Dec 11 - Dec 12
Total with taxes and fees
Farmhouse Oasis

Vacation Home in Drake

9.8 out of 10, Exceptional, (7)
"Great location. Close to Drake. Clean home. Great space for our trip."
United States
Katie H.
$408 nightly
The price is $457
Dec 10 - Dec 11
Total with taxes and fees
Spacious 4-bedroom house central to Des Moines near Drake Univ. Fenced yard

Cottage in Woodland Heights

2.0 star property
10.0 out of 10, Exceptional, (2)
"Cozy, had everything we needed, convenient "
United States
Jordan S.
Cozy Cottage Near Downtown Walkable to Dining and Boutique Shopping

Apartment in West Des Moines

9.4 out of 10, Exceptional, (10)
"Just as advertise prompt response from host clean and apt was as advertised!! Great stay"
United States
Raul N.
$174 nightly
The price is $176
Dec 14 - Dec 15
Total with taxes and fees
West Des Moines- Garage, Gym, Pool, Jordan Creek

Vacation Home in West Des Moines

9.4 out of 10, Exceptional, (38)
"We didn't spend much time at the house. We were working near by and just needed a place to eat, shower and sleep. We liked the place and would recommend it to others!"
United States
Tiffany L.
Gem in West Dsm | 4BD/3BA Home | Perfect Location

Vacation Home in Waukee

2.0 star property
9.0 out of 10, Wonderful, (12)
"House was super clean and spacious. Owner was very responsive. Will stay again!"
United States
Kelly T.
A Daybreak Stay

Vacation Home in Woodland Heights

10.0 out of 10, Exceptional, (66)
"Wonderful, Close to everything we wanted to do. Very clean and had comfy bed "
United States
M&S D.
$293 nightly
The price is $328
Dec 10 - Dec 11
Total with taxes and fees
The Cow Tipper: Near Everything - SPA - Game Room - Fire Pit & Patio - Sleeps 10

Vacation Home in Southwestern Hills

10.0 out of 10, Exceptional, (4)
"Beautiful place, good view from the deck. "
United States
Cory S.
$257 nightly
The price is $287
Dec 11 - Dec 12
Total with taxes and fees
Centrally Located Wooded A-Frame

Vacation Home in Urbandale

9.6 out of 10, Exceptional, (11)
"Clean and well kept, nice place to stay "
United States
Cooper L.
$269 nightly
The price is $301
Dec 14 - Dec 15
Total with taxes and fees
Newly remodeled 3-bedroom ranch with pool table, patio, and grill in Urbandale.

Vacation Home in West Des Moines

9.8 out of 10, Exceptional, (50)
"Good spot for family birthday and reunion"
United States
Nick K.
Executive Living 2min to Jordan Creek 6 bed/5 bath Near Jordan Creek Mall
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top De Soto Hotel Reviews

Find out more about De Soto

Everything you need to know about De Soto vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the De Soto vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect De Soto vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

De Soto vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in De Soto. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit De Soto in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $176 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on De Soto rentals

At Expedia, we put the best De Soto vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top De Soto rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream De Soto vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around De Soto. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in De Soto?

Yes, there are vacation rentals close to top local attractions in De Soto, or you can go with a more secluded option if you're looking for relaxation. De Soto is known for its shopping and restaurants. Make sure you have time to check out the bars while you're in the area.

What are some of the best vacation home rentals that De Soto has to offer?

AMAZING & A PARTY BARN… HOT TUB, PL TBl, PNG PNG, & ARCADE! ACCESS TO POOLS!: This vacation home rental near De Soto offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 6 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a garden, a selection of games, and a hot tub so you can immerse yourself in your vacation.

What’s there to see and do in De Soto?

While exploring the area, visit family-friendly sights like Clive Aquatic Center, or get outside and enjoy nature at Raccoon River Valley Trail. Topgolf and The MidAmerican Energy Company RecPlex are a couple of places you'll find in the larger area.

What’s a vacation rental in De Soto like?

Vacation rentals are privately owned properties you can stay in for a few weeks or just a few days in De Soto. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about a sanitized environment, vacation rentals can offer a sense of seclusion away from public hotel elevators and lobbies packed with people while still allowing you to travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular option for family trips.