De Soto Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
May 22 - May 24
In two months
Jul 3 - Jul 5
In three months
Jul 31 - Aug 2
In four months
Aug 28 - Aug 30

Our top choices for De Soto vacation rentals

Interior

NEW REMODEL! ARCADE GAMES, PNG PNG, SKEE BALL, ACCESS TO POOL. WE HAVE IT ALL!

NEW REMODEL! ARCADE GAMES, PNG PNG, SKEE BALL, ACCESS TO POOL. WE HAVE IT ALL!
Urbandale
9.4 out of 10, Exceptional, (81 reviews)
"Nice place to stay"
United States
kevin s.
$390 nightly
The price is $437
May 7 - May 8
Total with taxes and fees
NEW REMODEL! ARCADE GAMES, PNG PNG, SKEE BALL, ACCESS TO POOL. WE HAVE IT ALL!
Exterior

The Carmel/Bold/Massage /Chair Spacious / 3D Wall / Pool / Gym / Tanning Bed

The Carmel/Bold/Massage /Chair Spacious / 3D Wall / Pool / Gym / Tanning Bed
West Des Moines
9.8 out of 10, Exceptional, (24 reviews)
"Great location very nice apartment "
United States
Cindy P.
$217 nightly
The price is $243
May 7 - May 8
Total with taxes and fees
The Carmel/Bold/Massage /Chair Spacious / 3D Wall / Pool / Gym / Tanning Bed
Interior

Spacious 4BR Home • WiFi • Family-Friendly • Waukee

Spacious 4BR Home • WiFi • Family-Friendly • Waukee
Waukee
10.0 out of 10, Exceptional, (29 reviews)
"Beautiful home. We were only there for a few hours to sleep after a wedding, but it made me sad to leave. Wish I had a reason to go back to Iowa!! Definitely recommend this house!"
United States
Rita
$352 nightly
The price is $394
May 7 - May 8
Total with taxes and fees
Spacious 4BR Home • WiFi • Family-Friendly • Waukee
Exterior

1-bedroom, 3 Gig-Fiber WiFi, timbered/view setting in WDM near RecPlex/DMU

1-bedroom, 3 Gig-Fiber WiFi, timbered/view setting in WDM near RecPlex/DMU
West Des Moines
8.8 out of 10, Excellent, (8 reviews)
"The location was absolutely perfect being on the very edge of Des Moines. It was quiet, no city distractions and very private. The space was very clean and Clayton was very friendly and personable. We definitely would stay again!"
United States
Melissa C.
$159 nightly
The price is $178
May 7 - May 8
Total with taxes and fees
1-bedroom, 3 Gig-Fiber WiFi, timbered/view setting in WDM near RecPlex/DMU
Interior

Endless Fun! Family Home w/ Spacious Yard in Clive

Endless Fun! Family Home w/ Spacious Yard in Clive
3.0 star property
Clive
$421 nightly
The price is $472
May 11 - May 12
Total with taxes and fees
Endless Fun! Family Home w/ Spacious Yard in Clive
Smart TV

Centrally Located Wooded A-Frame

Centrally Located Wooded A-Frame
Southwestern Hills
10.0 out of 10, Exceptional, (15 reviews)
"Great space for an in-town getaway, close to downtown and West Des Moines."
United States
Joe B.
$250 nightly
The price is $280
May 12 - May 13
Total with taxes and fees
Centrally Located Wooded A-Frame
TV, fireplace, offices

Spacious home for 12 with large family room, deck, and peaceful views

Spacious home for 12 with large family room, deck, and peaceful views
Granger
10.0 out of 10, Exceptional, (6 reviews)
"My stay was very comfortable and pleasant"
United States
ashley g.
$412 nightly
The price is $462
May 7 - May 8
Total with taxes and fees
Spacious home for 12 with large family room, deck, and peaceful views
TV, offices

Comfortable 3-bedroom, 1.5-bathroom duplex apartment with full kitchen, laundry, and off-street parking. Minutes from Drake University and downtown Des Moines.

Comfortable 3-bedroom, 1.5-bathroom duplex apartment with full kitchen, laundry, and off-street parking. Minutes from Drake University and downtown Des Moines.
Waterbury
7.6 out of 10, Good, (8 reviews)
"Great place! Worked very well for the 4 of us. Thanks very much. We will stay here again in the future!"
United States
Tom H.
$294 nightly
The price is $309
May 11 - May 12
Total with taxes and fees
Comfortable 3-bedroom, 1.5-bathroom duplex apartment with full kitchen, laundry, and off-street parking. Minutes from Drake University and downtown Des Moines.
Smart TV

Adorable 1 bedroom duplex in quiet neighborhood.

Adorable 1 bedroom duplex in quiet neighborhood.
Waterbury
9.6 out of 10, Exceptional, (7 reviews)
"Cozy, clean and comfy! We loved the space, especially the comfy bed and the well stocked kitchen -- everything you need to prep and eat. The Walnut Creek trail was one block away -- perfect for walking and riding. We were there to visit our Drake student. It was easy-peasy to get to and from campus."
United States
Mary O.
$125 nightly
The price is $140
May 12 - May 13
Total with taxes and fees
Adorable 1 bedroom duplex in quiet neighborhood.
Exterior

Sleepover | Alluring 1BD/1BA - Des Moines

Sleepover | Alluring 1BD/1BA - Des Moines
West Des Moines
$176 nightly
The price is $199
May 7 - May 8
Total with taxes and fees
Sleepover | Alluring 1BD/1BA - Des Moines
Smart TV, offices

Roomy 4BR by Drake Sleeps 13 HUGE yard

Roomy 4BR by Drake Sleeps 13 HUGE yard
Drake
7.0 out of 10, Good, (9 reviews)
"Good"
United States
Laurie P.
$289 nightly
The price is $304
May 12 - May 13
Total with taxes and fees
Roomy 4BR by Drake Sleeps 13 HUGE yard
Fridge, microwave, oven, stovetop

LUXURY GETAWAY! ARCADE, POOL TBL, PING PONG, HOT TUB, DECK! ACCESS TO POOLS!

LUXURY GETAWAY! ARCADE, POOL TBL, PING PONG, HOT TUB, DECK! ACCESS TO POOLS!
Waukee
9.6 out of 10, Exceptional, (83 reviews)
"Great house for a weekend of family get togethers! Had something for all ages and was so well stocked with everything we could have needed! "
United States
Keri R.
$468 nightly
The price is $524
May 11 - May 12
Total with taxes and fees
LUXURY GETAWAY! ARCADE, POOL TBL, PING PONG, HOT TUB, DECK! ACCESS TO POOLS!
Bar (on property)

Elegant 4BR Agrihood Home | Farm-to-Table Living Near Des Mo, "Luxurious Retreat in Iowa's First Agr...

Elegant 4BR Agrihood Home | Farm-to-Table Living Near Des Mo, "Luxurious Retreat in Iowa's First Agr...
Cumming
10.0 out of 10, Exceptional, (11 reviews)
"Great place to stay!"
United States
Elizabeth V.
$498 nightly
The price is $557
May 7 - May 8
Total with taxes and fees
Elegant 4BR Agrihood Home | Farm-to-Table Living Near Des Mo, "Luxurious Retreat in Iowa's First Agr...
Smart TV, printers

Good Vibes 2-Bedroom Apartment in Waukee - Central Location & Modern Comforts

Good Vibes 2-Bedroom Apartment in Waukee - Central Location & Modern Comforts
Waukee
10.0 out of 10, Exceptional, (11 reviews)
"Great place to stay. A perfect location for us."
United States
Robert P.
$220 nightly
The price is $246
May 10 - May 11
Total with taxes and fees
Good Vibes 2-Bedroom Apartment in Waukee - Central Location & Modern Comforts
TV

Beautiful 3-bedroom house with AC in adorable Des Moines

Beautiful 3-bedroom house with AC in adorable Des Moines
Beaverdale
9.4 out of 10, Exceptional, (8 reviews)
"Great location close to friends. Hosts were great with awesome communication. "
United States
Karen G.
$232 nightly
The price is $260
May 11 - May 12
Total with taxes and fees
Beautiful 3-bedroom house with AC in adorable Des Moines
Fridge, microwave, oven, stovetop

Home w/Hot Tub -Spacious, Quiet Neighborhood Near Des Moines, IA.

Home w/Hot Tub -Spacious, Quiet Neighborhood Near Des Moines, IA.
Clive
10.0 out of 10, Exceptional, (20 reviews)
"The house is nicely equipped and very comfortable. We enjoyed our stay! "
United States
Kristin H.
$480 nightly
The price is $538
May 12 - May 13
Total with taxes and fees
Home w/Hot Tub -Spacious, Quiet Neighborhood Near Des Moines, IA.
Terrace/patio

Spacious 4-bedroom house central to Des Moines near Drake Univ. Fenced yard

Spacious 4-bedroom house central to Des Moines near Drake Univ. Fenced yard
Drake
9.8 out of 10, Exceptional, (10 reviews)
"Loved your place RyanThanks for adding to a wonderful family get together"
United States
Dan V.
$436 nightly
The price is $488
May 7 - May 8
Total with taxes and fees
Spacious 4-bedroom house central to Des Moines near Drake Univ. Fenced yard
Smart TV, fireplace, video games, table tennis

SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!

SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!
Woodland Heights
9.4 out of 10, Exceptional, (76 reviews)
"We had a great family weekend in Des Moines. The house is fantastic for a large group. Nice kitchen, dining and living areas. Plenty of bedrooms and nice bathrooms. The game room in the basement was super fun! Everyone had plenty of space and a great time! When we arrived the front door was open and two men were in the entryway with large equipment. They seem to have been repairing the kitchen floor. That was odd, and awkward, but it seemed fine. There was a layer of dust on every...
United States
Diane
$468 nightly
The price is $524
May 10 - May 11
Total with taxes and fees
SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!
Exterior

Sleepover | Marvelous 1BD/1BA - Des Moines

Sleepover | Marvelous 1BD/1BA - Des Moines
West Des Moines
10.0 out of 10, Exceptional, (4 reviews)
"We stayed at the Flux apartments in downtown. Our accommodation was exceptional in all respects. Thank you for your hospitality!"
United States
Miriam G.
$176 nightly
The price is $199
May 7 - May 8
Total with taxes and fees
Sleepover | Marvelous 1BD/1BA - Des Moines
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top De Soto Hotel Reviews

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

10/10 Excellent
"Very clean and well maintained hotel. Staff were accommodating and helpful from check in until we departed. Parking area well lit and very clean. Will book here again! Did not have breakfast but the coffee and juice/ tea are 5 stars! Our total stay was 4 days."
Frank 4-night trip
Posted 1 hour ago
Days Inn & Suites by Wyndham Des Moines Airport

Find out more about De Soto

Everything you need to know about De Soto vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the De Soto vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect De Soto vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

De Soto vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in De Soto. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit De Soto in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $178 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on De Soto rentals

At Expedia, we put the best De Soto vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top De Soto rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream De Soto vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around De Soto. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in De Soto?

Yes, there are vacation rentals close to top local attractions in De Soto, or you can go with a more secluded option if you're looking for relaxation. De Soto is known for its shopping and restaurants. Make sure you have time to check out the bars while you're in the area.

What are some of the best vacation home rentals that De Soto has to offer?

Beautiful 3-bedroom house with AC in adorable Des Moines: This vacation home near De Soto offers a patio, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

What’s there to see and do in De Soto?

While exploring the area, visit family-friendly sights like Bob Feller Museum, or get outside and enjoy nature at Raccoon River Valley Trail. Waukee City Hall and Topgolf are a couple of places you'll find in the larger area.

What’s a vacation rental in De Soto like?

Vacation rentals are privately owned properties you can stay in for a few weeks or just a few days in De Soto. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about a sanitized environment, vacation rentals can offer a sense of seclusion away from public hotel elevators and lobbies packed with people while still allowing you to travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular option for family trips.