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Our top choices for Des Moines vacation homes
Downtown Skyline Views in Modern Townhome with Rooftop Patios
Downtown Skyline Views in Modern Townhome with Rooftop PatiosDowntown Des Moines
10.0 out of 10, Exceptional, (42)
"A great place to stay if visiting Des Moines!"
Justine
$209 nightly
The price is $234
Dec 24 - Dec 25
Total with taxes and fees
Brand New 2025 Home in Urbandale/Des Moines – Modern Comfort In Prime Location!
Brand New 2025 Home in Urbandale/Des Moines – Modern Comfort In Prime Location!Urbandale
10.0 out of 10, Exceptional, (2)
"This was the perfect spot to stay for a visit to our relatives in Urbandale. It was minutes away from their home which made it super convenient. The home was very clean and cozy. The owner was great with communication and made our stay easy. We will definitely rent here again next time we visit Urbandale!"
Marci A.
$223 nightly
The price is $249
Dec 25 - Dec 26
Total with taxes and fees
Modern 3-Bed,2-Bath Retreat
Modern 3-Bed,2-Bath RetreatDes Moines
10.0 out of 10, Exceptional, (3)
"Great place for family vacation. Host was very responsive. Check in was easy / house was very clean, beds comfortable and great neighborhood. Definitely would stay again in back in the area! "
Susan
$333 nightly
The price is $373
Dec 24 - Dec 25
Total with taxes and fees
3-Bedroom Near Downtown w/ Backyard, Pet friendly!
3-Bedroom Near Downtown w/ Backyard, Pet friendly!Drake
$230 nightly
The price is $258
Dec 24 - Dec 25
Total with taxes and fees
5 Min to Adventureland and Casino - Fenced in yard
5 Min to Adventureland and Casino - Fenced in yardAltoona
9.8 out of 10, Exceptional, (7)
"This little house was perfect for our holiday weekend! Quiet neighborhood (even during fireworks) and easily accessible in Altoona. Property manager was easy to communicate with! Thanks for the great place to stay!"
Krista D.
$246 nightly
The price is $276
Jan 12 - Jan 13, 2026
Total with taxes and fees
Beautiful home minutes from downtown!
Beautiful home minutes from downtown!Des Moines
9.6 out of 10, Exceptional, (26)
"Clean house, comfortable beds, quiet neighborhood, good location "
William S.
$245 nightly
The price is $274
Dec 24 - Dec 25
Total with taxes and fees
2BR Family Charmer Duplex near Drake
2BR Family Charmer Duplex near DrakeDes Moines
7.0 out of 10, Good, (2)
"Booked this for Employee and they loved it..."
Ray
$363 nightly
The price is $378
Dec 24 - Dec 25
Total with taxes and fees
Entire Bungalow with Fenced-In Yard in Trendy Neighborhood, Central Des Moines
Entire Bungalow with Fenced-In Yard in Trendy Neighborhood, Central Des MoinesDes Moines
10.0 out of 10, Exceptional, (11)
"Booked two nights right in a row and loved it! Hopefully one day can stay again! Has everything you could need, very comfortable bed, lovely home! "
Kassidy C.
$149 nightly
The price is $166
Dec 29 - Dec 30
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Des Moines Hotel Reviews
Hampton Inn Des Moines-Airport
10/10 Excellent
Find out more about Des Moines
Des Moines Vacation Homes information
Number of reviews | 233 |
|---|---|
Accommodation | 216 Vacation Homes |
Lowest Price | $166 |
Highest Price | $1,003 |
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- Visit Iowa
- Simon Estes Riverfront Amphitheater
- Walnut Street Bridge
- World Food Prize Hall of Laureates
- Des Moines Civic Center
- Iowa Women of Achievement Bridge
- Greater Des Moines Botanical Garden
- Iowa Hall of Pride
- Hy Vee Hall
- Visit Historic East Village
- Science Center of Iowa
- Visit Downtown Des Moines
- Wells Fargo Arena
- Community Choice Credit Union Convention Center
- Downtown Des Moines Vacations