Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Des Plaines Best Western Hotels

See all 761 Hotels in Des Plaines
Best Western O'Hare/Elk Grove Hotel

Best Western O'Hare/Elk Grove Hotel

100 Busse Rd, Elk Grove Village
4.0 out of 5.0
4.0 out of 5 (281 reviews)
Great hotel for the price Comfortable bed, clean room. Would like two queen beds instead of two doubles, but that can't be he … - 

$70

$70
Map

Recently booked Des Plaines hotels

Wyndham Chicago O'Hare
3.5 out of 5.0
Last booking: 54 minutes ago
Comfort Inn O'Hare - Convention Center
3.5 out of 5.0
Last booking: 1 hour ago
Hilton Garden Inn Chicago/O'Hare Airport
3.5 out of 5.0
Last booking: 5 hours ago
Extended Stay America - Chicago - O'Hare
3.0 out of 5.0
Last booking: 7 hours ago
Best Western Des Plaines Inn
2.5 out of 5.0
Last booking: 20 hours ago
Courtyard by Marriott Chicago O'Hare
3.5 out of 5.0
Last booking: 20 hours ago

Best Western Des Plaines Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Best Western hotels in Des Plaines, Chicago. Known for well-appointed rooms and friendly, personalized service, each of the top Best Western Des Plaines hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Des Plaines Best Western locations may even offer extra little benefits and discounts for frequent travelers.