Adults Only Resorts & Hotels in South Carolina
Check availability on South Carolina Adults Only Resorts & Hotels
Pick from 42 South Carolina Adults Only Resorts & Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

86 Cannon Charleston - Adults Only
86 Cannon Charleston - Adults Only
10.0 out of 10, Exceptional, (71)

Affordable Suites Myrtle Beach
Affordable Suites Myrtle Beach
8.6 out of 10, Excellent, (288)

Baymont by Wyndham Orangeburg North
Baymont by Wyndham Orangeburg North
6.0 out of 10, (1000)

Beach Lover's Condo With Spectacular Ocean View, Pool, Lazy River, & Jacuzzi!
Beach Lover's Condo With Spectacular Ocean View, Pool, Lazy River, & Jacuzzi!
10.0 out of 10, Exceptional, (23)

Detached Guest Suite
Detached Guest Suite
10.0 out of 10, Exceptional, (198)

Downtown-One-of-a-Kind Romantic Luxury Residence 5BR, 3BA Sleeps 10 to 12
Downtown-One-of-a-Kind Romantic Luxury Residence 5BR, 3BA Sleeps 10 to 12
9.8 out of 10, Exceptional, (64)

Historic District Downtown 344 & A Half On King Street
Historic District Downtown 344 & A Half On King Street
10.0 out of 10, Exceptional, (93)

Historic District Downtown 344 King Street
Historic District Downtown 344 King Street
9.8 out of 10, Exceptional, (106)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Carolina Hotel Reviews

Sea Crest Oceanfront Resort
10/10 Excellent
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Top destinations for Adults Only Resorts & Hotels in South Carolina
More Hotel Options in South Carolina
- Extended Stay Hotels in South Carolina
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- Hotels with Free Wifi in South Carolina
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- Non-Smoking Hotels in South Carolina
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- Hotels with Hot Tubs in South Carolina
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- Hotel Wedding Venues
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Other Accommodation Types in South Carolina
Stay near popular South Carolina attractions
- Hotels near Fort Jackson
- Hotels near Myrtle Beach Boardwalk
- Hotels near Port of Charleston
- Hotels near Carowinds Theme Park
- Hotels near Broadway at the Beach
- Hotels near Marine Corps Recruit Depot Parris Island
- Hotels near University of South Carolina
- Hotels near Clemson University
- Hotels near Ripley's Aquarium
- Hotels near College of Charleston
Discover hotels close to South Carolina with room rates, reviews, and availability. Most hotels are fully refundable.
- Emeline
- Sea Crest Oceanfront Resort
- Holiday Inn Charleston Riverview by IHG
- Sonesta Resort Hilton Head Island
- Hilton Beachfront Resort & Spa Hilton Head Island
- Holiday Inn Express & Suites Charleston Dwtn - Westedge by IHG
- Anderson Ocean Club and Spa by Oceana Resorts
- Hilton Grand Vacations Club Ocean Enclave Myrtle Beach
- La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy
- The Ellie Beach Resort Myrtle Beach, Tapestry By Hilton
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