Title: The Best 2 Star Hotels in Florence, SC from $46 | Expedia.com [Florence Travel Guide](https://expedia.com/Florence.dx1221)[Hotels in Florence](https://expedia.com/Florence-Hotels.d1221.Travel-Guide-Hotels)[Vacation Rentals in Florence](https://expedia.com/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.com/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Things to do in Florence](https://expedia.com/Things-To-Do-In-Florence.d1221.Travel-Guide-Activities)[Car Rentals in Florence](https://expedia.com/Car-Rentals-In-Florence.d1221.Car-Rental-Guide)[Florence Vacation Packages](https://expedia.com/Florence.d1221.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check availability on Florence 2 Star Hotels Tonight [Mar 13 - Mar 14](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-13&endDate=2026-03-14&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 14 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-14&endDate=2026-03-15&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Florence 2-star hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking (1st Floor) | Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/f9691b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/e7174d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) Florence 8.6/10 Excellent (2,574 reviews) "Can’t beat the price for a clean room, comfy bed and complementary breakfast items. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary $67 nightly $75 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fad493a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/6df606aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fefdad76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area [](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) Florence 9.2/10 Wonderful (1,222 reviews) "Clean room, good breakfast...very nice overnight stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gerry $102 nightly $114 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/d6de6ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/dab62d55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/3ba2ede7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence/I-95 North [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) Florence 6.8/10 (1,001 reviews) "Great room and reasonable price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hattab $62 nightly $70 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/1c348a37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/dc8d999b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/f82666ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center [](https://www.expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) Florence 7.8/10 Good (1,270 reviews) "Clean, quiet and safe location to spend the night. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) David $90 nightly $101 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/114000000/113640000/113638700/113638614/9722c1f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/114000000/113640000/113638700/113638614/bc0d675a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible, Non Smoking | Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/114000000/113640000/113638700/113638614/62a64c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/114000000/113640000/113638700/113638614/203e10ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Sumter Near Shaw Afb [](https://www.expedia.com/Sumter-Hotels-Woodspring-Suites-Sumter-Near-Shaw-Afb.h113638614.Hotel-Information) Sumter 8.2/10 Very Good (180 reviews) "Young lady was very friendly and helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yocasia $119 nightly $133 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Sumter-Hotels-Woodspring-Suites-Sumter-Near-Shaw-Afb.h113638614.Hotel-Information) ![Room, 1 Queen Bed, Accessible, Non Smoking | In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/73965d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/cbd95825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/2d26ec35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) Florence 6.8/10 (1,001 reviews) "Friendly staff, clean room, very comfortable bed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Willie $61 nightly $68 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/ffaddd2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/bdf580c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/689a1cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/83cb7582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) Florence 8.4/10 Very Good (1,011 reviews) "The stay was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dianne $131 nightly $147 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/1000000/994200/994155/c85bf0e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/1000000/994200/994155/faa2d610.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/994200/994155/a86d7fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/1000000/994200/994155/3d2701b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Lumberton, NC [](https://www.expedia.com/Lumberton-Hotels-Motel-6-Lumberton.h994155.Hotel-Information) Lumberton 5.8/10 (386 reviews) "Yess" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacquline $41 nightly $46 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Lumberton-Hotels-Motel-6-Lumberton.h994155.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/76254b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/009ea869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/31819118.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Accessible, Non Smoking (Roll-In Shower) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/2b946657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Dillon, SC [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Dillon.h12827.Hotel-Information) Dillon 6.4/10 (1,001 reviews) "Nice rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaqwonda $56 nightly $63 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Dillon.h12827.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/9c0353ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/6c72c859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Accessible (Communications, Mobility, Access Tub) | In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/cfd93cd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/07b3e89f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) Florence 9.2/10 Wonderful (1,001 reviews) "Awesome stay—fantastic staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie $127 nightly $142 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/20f68e84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/8339db76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/d5b1a48f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Florence I-95 [](https://www.expedia.com/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) Florence 8.4/10 Very Good (1,001 reviews) "Everything was great...clean property and friendly staff! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lasonia $101 nightly $113 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/995e3ecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/59604fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/a2c60bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/3e9ccd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-North-I-95 [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) Florence 9.0/10 Wonderful (873 reviews) "Busy hotel. Nice rooms awesome free breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ken $110 nightly $123 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Premium bedding, pillowtop beds, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/1000000/10000/500/455/ef1db617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/500/455/5074ad24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/500/455/be7cdd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/500/455/344e3fdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Inn [](https://www.expedia.com/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) Florence 7.8/10 Good (1,000 reviews) "Very friendly staff. The room was very spacious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arika $99 nightly $111 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1f011cac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/bac50e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d1f8ba02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence Near Civic Center [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) Florence 7.0/10 Good (1,003 reviews) "Everything was great. I slept very well. Bed and linen were clean. Staff was friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elvira $60 nightly $68 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/ddbd2495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/f19c2d4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/68010423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/8b770330.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Florence [](https://www.expedia.com/Florence-Hotels-Hilton-Garden-Inn-Florence.h1367205.Hotel-Information) Florence 8.6/10 Excellent (288 reviews) "Very nice stay. Very clean hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mark $114 nightly $128 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hilton-Garden-Inn-Florence.h1367205.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/06692e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/w6955h4642x8y0-4ae289f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/7e5ec8df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/59da7dea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at the Crossroads [](https://www.expedia.com/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) Lake City 9.4/10 Exceptional (860 reviews) "Very nice staff, peaceful location very clean up-to-date modern" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shayvan $152 nightly $171 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/c68ab7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/5054dc3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/67a43c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/d963a865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Florence I-95 [](https://www.expedia.com/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) Florence 8.4/10 Very Good (1,000 reviews) "Great accommodations and courteous staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie $107 nightly $119 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) ![Blackout drapes, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/ae830b76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/bbdb0658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/0c25e0a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, shampoo, toilet paper](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/33c86cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Sumter [](https://www.expedia.com/Sumter-Hotels-Red-Roof-Inn-Sumter.h1281499.Hotel-Information) Sumter 6.8/10 (288 reviews) "The lady that checked me in was super nice! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole $110 nightly $123 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Sumter-Hotels-Red-Roof-Inn-Sumter.h1281499.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/130000/126000/125974/9d8dbfb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/130000/126000/125974/edc120df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/130000/126000/125974/fdbe8e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, 2 Double Beds, Non Smoking | Pillowtop beds, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/1000000/130000/126000/125974/b2c0fee2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Laurinburg [](https://www.expedia.com/Rockingham-Hotels-Quality-Inn-Laurinburg.h125974.Hotel-Information) Laurinburg 7.4/10 Good (422 reviews) "Breakfast was good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David $80 nightly $90 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Rockingham-Hotels-Quality-Inn-Laurinburg.h125974.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/778f48dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/0da1bc1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/da02b608.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/25ba1b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Executive Inn [](https://www.expedia.com/Florence-Hotels-Best-Western-Executive-Inn.h1202776.Hotel-Information) Latta 8.2/10 Very Good (964 reviews) "Would definitely stay again !!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy $106 nightly $116 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Best-Western-Executive-Inn.h1202776.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Florence-Hotels.s20-0-d1221.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Florence-Hotels.s20-0-d1221.Travel-Guide-Filter-Hotels) ## Explore similar 3-star hotels Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Florence. ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hyatt Place Florence Downtown 100 East Evans Street Florence Florence SC $118 nightly $132 total Mar 30 - Mar 31 Total with taxes and fees 9/10 Wonderful! (1,001 reviews) [](https://expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![SpringHill Suites by Marriott Florence](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/bad3cc5c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### SpringHill Suites by Marriott Florence 2670 Hospitality Blvd Florence SC $106 nightly $119 total Mar 16 - Mar 17 Total with taxes and fees 8.6/10 Excellent! (1,013 reviews) [](https://expedia.com/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) ![Fairfield Inn by Marriott Hartsville](https://images.trvl-media.com/lodging/1000000/210000/202900/202854/1397c485_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn by Marriott Hartsville 200 S 4th St Hartsville SC $88 nightly $99 total Mar 16 - Mar 17 Total with taxes and fees 8.6/10 Excellent! (708 reviews) [](https://expedia.com/Florence-Hotels-Fairfield-Inn-By-Marriott-Hartsville.h202854.Hotel-Information) Still don't see what you're looking for? [See all properties in Florence.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F15%2F2026&endDate=3%2F16%2F2026®ionId=1221&star=20) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F15%2F2026&endDate=3%2F16%2F2026®ionId=1221&star=20&star=20&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F15%2F2026&endDate=3%2F16%2F2026®ionId=1221&star=20&star=20&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F15%2F2026&endDate=3%2F16%2F2026®ionId=1221&star=20&star=20&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F15%2F2026&endDate=3%2F16%2F2026®ionId=1221&star=20&star=20&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F15%2F2026&endDate=3%2F16%2F2026®ionId=1221&star=20&star=20&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Florence and related destinations - Florence - Mahwah - Nanuet - Katy - Texarkana - Rolla Stroll through the West Broad Street Historic District to soak up local history before exploring the Florence Museum's diverse exhibits. Catch a show at the Florence Civic Center or hunt for bargains at Magnolia Mall for a taste of modern entertainment. [See all hotels in Florence](https://www.expedia.com/Hotel-Search?startDate=2026-03-28&endDate=2026-03-29&adults=2®ionId=1221) ![Wyche Pavilion Greenville South Carolina ](https://images.trvl-media.com/place/1221/22638cec-95e4-4f53-af15-3963f8a47f19.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top Florence Hotel Reviews ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 8/10 Good "We were only booked for one night. The hotel was clean and the gentleman at the desk was very friendly. Our room was very clean and the location was very quiet. " [](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9_y.jpg) ### Days Inn by Wyndham Florence/I-95 North 6/10 Okay "It was ok" [](https://expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Microtel Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c_y.jpg) ### Microtel Inn & Suites by Wyndham Florence 10/10 Excellent "I liked it so much on the way down to Florida from New Jersey that i stayed there on the way back. Staff was very accommodating. I hit tons of traffic on the way there and back and they held my room until long after midnight. " [](https://expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ## Price trends for properties with 2 Stars in Florence | Less expensive | More expensive | This month | Next month | | -------------- | -------------- | ---------- | ---------- | | February | March | $102 | $92 | | Month | Price | | --------- | ----- | | January | $89 | | February | $84 | | March | $102 | | April | $92 | | May | $95 | | June | $91 | | July | $93 | | August | $90 | | September | $95 | | October | $94 | | November | $92 | | December | $92 | Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed properties with 2 stars in Florence. Select dates and complete search for nightly totals inclusive of taxes and fees. ## Find out more about Florence When it's time for an affordable family getaway, a weekend away with your special someone, or a simple solo escape, book a Florence 2 Star Hotel. To find out why this is a region becomes more popular each day, enjoy top-notch amenities and explore interesting attractions. Find a new favorite bakery or plaza nearby and while away the day, or stay on your feet visiting top attractions that draw several of devoted visitors to Florence. You're about to find out why locals and travelers alike love this place. ### The Right Hotel at the Ideal Price 2 Star hotels are in high demand in Florence. You'll find the best deals right here, so book early and save on a great getaway. Thanks to several convenient locations and comfortable amenities, you'll find accommodation that suits your vacation style. Be one of the first travelers to write a review and share your experience. So, savor the comfort of a well-kept room and attentive hospitality. With our travel deals, the world is wide open to you one hotel at a time, and the journey starts in Florence. ### Book Your Two-Star 2 Star Hotel Today! Plan your trip to Florence now with Expedia's easy online travel booking and start relaxing before you even leave the house. If you need a break from the crowds, you may find that this region offers just the reprieve you've been looking for. Take advantage of the 2 Star Hotel availability and easy-going atmosphere. ## Frequently asked questions ### How much does it cost to stay in a 2-star hotel in Florence? ### What are the most highly rated Florence 2-star hotels? > Another excellent choice is the [Hampton Inn & Suites Florence Center](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information), which also enjoys a great rating of 9.2 from travelers. This property features spacious rooms equipped with kitchen amenities like microwaves and refrigerators, ideal for families who appreciate the ease of preparing snacks or light meals. The inviting space and attentive service make it a great base for exploring the area or enjoying quality time with loved ones. > > > If you're traveling for business or as a couple, the [Comfort Inn & Suites](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information), rated the same at 9.2, offers fantastic fitness facilities to keep you active during your stay. Its accessible fitness center allows you to maintain your routine, while the hotel's comfortable ambiance provides a peaceful retreat after a busy day. ### Are there 2-star Florence hotels that offer free breakfast? > Equally appealing is the Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center, which also enjoys a stellar rating of 9.2\. This hotel features a delicious free buffet breakfast, ensuring that travelers can fuel up for their day of activities. > > > Lastly, the [Hampton Inn & Suites Florence Center](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) matches the quality and service of its counterparts, with the same commendable review score of 9.2\. Here, you can enjoy a complimentary breakfast while basking in the comfort of a well-appointed room. ### What 2-star hotels in Florence have free parking? > Equally appealing is the [Hampton Inn & Suites Florence Center](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information), which shares the same stellar rating of 9.2\. This hotel also provides complimentary self-parking, along with accessible parking options, making it great for families or travelers with special needs. Guests appreciate the inviting environment and attentive service, which enhance their overall experience. > > > Another great choice is the [Hampton Inn & Suites Florence-North-I-95](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information), rated at 9.0\. Like its counterparts, this hotel offers free self-parking and accessible parking, ensuring that convenience is at the forefront of your stay. With its comfortable accommodations and friendly staff, it's an ideal option for those seeking quality and ease during their travels. ### Are there family-friendly 2-star hotels in Florence? > Similarly, the [Comfort Inn & Suites](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) also shines with a stellar rating of 9.2\. It provides a refreshing pool, superb for cooling off after a day of exploring, and family-friendly conveniences like a microwave and daily housekeeping to keep your stay carefree and enjoyable. > > > Another great option is the [Hampton Inn & Suites Florence Center](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information), which matches the 9.2 rating and enhances the family experience with both a pool and highchairs available for the little ones. With additional amenities such as a kitchen and microwave, this hotel makes it easy to prepare snacks or meals, adding to your convenience during your stay. ### Are there any 2-star Florence hotels with a pool? > The Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center by IHG also boasts an excellent customer review score of 9.2 and features an inviting indoor pool, which is ideal for families who want to enjoy some splash time regardless of the weather outside. > > > Additionally, the [Hampton Inn & Suites Florence Center](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information), with the same great rating of 9.2, offers both an outdoor pool and a friendly feel, making it a fantastic choice for those traveling with children. ### Can I find pet-friendly 2-star hotels in Florence? > Another excellent choice is the [Hampton Inn & Suites Florence Center](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information), which also boasts a stellar rating of 9.2\. This hotel is pet-friendly, accommodating both dogs and cats, and provides a inviting space superb for families seeking convenience and comfort. > > > Lastly, the [Park Inn by Radisson Florence, SC](https://www.expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information), with a traveler review rating of 9.0, offers a similarly pet-friendly environment. Alongside welcoming pets, this hotel enhances your stay with thoughtful touches like food and water bowls, making it an ideal option for those traveling with their four-legged friends. ### What is the difference between a 2-star Florence hotel and a 3-star hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Station ](https://www.expedia.com/Florence-Station-Hotels.d6195493.Travel-Guide-Hotels) - [Hotels near Florence Museum ](https://www.expedia.com/Florence-Museum-Hotels.0-l6162137-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence National Cemetery ](https://www.expedia.com/Florence-National-Cemetery-Hotels.0-l553248621532657341-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Regional ](https://www.expedia.com/Florence-Regional-Airport-Hotels.0-aFLO-0.Travel-Guide-Filter-Hotels) - 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[Flights from Hartford (BDL) to Florence (FLO) ](https://www.expedia.com/lp/flights/bdl/flo/hartford-to-florence) - [Flights from Tampa (TPA) to Florence (FLO) ](https://www.expedia.com/lp/flights/tpa/flo/tampa-to-florence) - [Flights from Greenville (GSP) to Florence (FLO) ](https://www.expedia.com/lp/flights/gsp/flo/greenville-to-florence) - [Flights from Dallas (DFW) to Florence (FLO) ](https://www.expedia.com/lp/flights/dfw/flo/dallas-to-florence) - [Flights from Rochester (ROC) to Florence (FLO) ](https://www.expedia.com/lp/flights/roc/flo/rochester-to-florence) - [Flights from Orlando (MCO) to Florence (FLO) ](https://www.expedia.com/lp/flights/mco/flo/orlando-to-florence) - [Flights from Oklahoma City (OKC) to Florence (FLO) ](https://www.expedia.com/lp/flights/okc/flo/oklahoma-city-to-florence) - [Flights from Huntsville (HSV) to Florence (FLO) ](https://www.expedia.com/lp/flights/hsv/flo/huntsville-to-florence) - [Flights from Los Angeles (LAX) to Florence (FLO) ](https://www.expedia.com/lp/flights/lax/flo/los-angeles-to-florence) - [Flights from Phoenix (PHX) to Florence (FLO) ](https://www.expedia.com/lp/flights/phx/flo/phoenix-to-florence) - [Flights from Fort Lauderdale (FLL) to Florence (FLO) ](https://www.expedia.com/lp/flights/fll/flo/fort-lauderdale-to-florence) - [Flights from Miami (MIA) to Florence (FLO) ](https://www.expedia.com/lp/flights/mia/flo/miami-to-florence) - [Flights from Wilmington (ILM) to Florence (FLO) ](https://www.expedia.com/lp/flights/ilm/flo/wilmington-to-florence) - [Flights from Raleigh (RDU) to Florence (FLO) ](https://www.expedia.com/lp/flights/rdu/flo/raleigh-to-florence) - [Flights from Savannah (SAV) to Florence (FLO) ](https://www.expedia.com/lp/flights/sav/flo/savannah-to-florence) - [Flights from Memphis (MEM) to Florence (FLO) ](https://www.expedia.com/lp/flights/mem/flo/memphis-to-florence) - [Flights from San Diego (SAN) to Florence (FLO) ](https://www.expedia.com/lp/flights/san/flo/san-diego-to-florence) - [Flights from Sarasota (SRQ) to Florence (FLO) ](https://www.expedia.com/lp/flights/srq/flo/sarasota-to-florence) - [Flights from Denver (DEN) to Florence (FLO) ](https://www.expedia.com/lp/flights/den/flo/denver-to-florence) - [Flights from Seattle (SEA) to Florence (FLO) ](https://www.expedia.com/lp/flights/sea/flo/seattle-to-florence) - [Flights from Pittsburgh (PIT) to Florence (FLO) ](https://www.expedia.com/lp/flights/pit/flo/pittsburgh-to-florence) - [Flights from Detroit (DTW) to Florence (FLO) ](https://www.expedia.com/lp/flights/dtw/flo/detroit-to-florence) - [Flights from Albany (ALB) to Florence (FLO) ](https://www.expedia.com/lp/flights/alb/flo/albany-to-florence) - [Flights from Buffalo (BUF) to Florence (FLO) ](https://www.expedia.com/lp/flights/buf/flo/buffalo-to-florence) - [Flights from Lexington (LEX) to Florence (FLO) ](https://www.expedia.com/lp/flights/lex/flo/lexington-to-florence) - [Flights from Louisville (SDF) to Florence (FLO) ](https://www.expedia.com/lp/flights/sdf/flo/louisville-to-florence) - [Flights from Cleveland (CLE) to Florence (FLO) ](https://www.expedia.com/lp/flights/cle/flo/cleveland-to-florence) - [Flights from Austin (AUS) to Florence (FLO) ](https://www.expedia.com/lp/flights/aus/flo/austin-to-florence) - [Flights from San Francisco (SFO) to Florence (FLO) ](https://www.expedia.com/lp/flights/sfo/flo/san-francisco-to-florence) - [Flights from Greensboro (GSO) to Florence (FLO) ](https://www.expedia.com/lp/flights/gso/flo/greensboro-to-florence) - [Flights from Columbus (CMH) to Florence (FLO) ](https://www.expedia.com/lp/flights/cmh/flo/columbus-to-florence) - [Flights from Richmond (RIC) to Florence (FLO) ](https://www.expedia.com/lp/flights/ric/flo/richmond-to-florence) - [Flights from Augusta (AGS) to Florence (FLO) ](https://www.expedia.com/lp/flights/ags/flo/augusta-to-florence) - [Flights from Tucson (TUS) to Florence (FLO) ](https://www.expedia.com/lp/flights/tus/flo/tucson-to-florence) - [Flights from Birmingham (BHM) to Florence (FLO) ](https://www.expedia.com/lp/flights/bhm/flo/birmingham-to-florence) - [Flights from Syracuse (SYR) to Florence (FLO) ](https://www.expedia.com/lp/flights/syr/flo/syracuse-to-florence) - [Flights from Chattanooga (CHA) to Florence (FLO) ](https://www.expedia.com/lp/flights/cha/flo/chattanooga-to-florence) - [Flights from Dayton (DAY) to Florence (FLO) ](https://www.expedia.com/lp/flights/day/flo/dayton-to-florence) - [Flights from Indianapolis (IND) to Florence (FLO) ](https://www.expedia.com/lp/flights/ind/flo/indianapolis-to-florence) - [Flights from Norfolk (ORF) to Florence (FLO) ](https://www.expedia.com/lp/flights/orf/flo/norfolk-to-florence) - [Flights from Little Rock (LIT) to Florence (FLO) ](https://www.expedia.com/lp/flights/lit/flo/little-rock-to-florence) - [Flights from Minneapolis (MSP) to Florence (FLO) ](https://www.expedia.com/lp/flights/msp/flo/minneapolis-to-florence) - [Flights from Knoxville (TYS) to Florence (FLO) ](https://www.expedia.com/lp/flights/tys/flo/knoxville-to-florence) - [Flights from Newburgh (SWF) to Florence (FLO) ](https://www.expedia.com/lp/flights/swf/flo/newburgh-to-florence) - [Flights from London (LHR) to Florence (FLO) ](https://www.expedia.com/lp/flights/lhr/flo/london-to-florence) - [Flights from Daytona Beach (DAB) to Florence (FLO) ](https://www.expedia.com/lp/flights/dab/flo/daytona-beach-to-florence) - [Flights from Milwaukee (MKE) to Florence (FLO) ](https://www.expedia.com/lp/flights/mke/flo/milwaukee-to-florence) - [Flights from Sacramento (SMF) to Florence (FLO) ](https://www.expedia.com/lp/flights/smf/flo/sacramento-to-florence) - [Flights from Colorado Springs (COS) to Florence (FLO) ](https://www.expedia.com/lp/flights/cos/flo/colorado-springs-to-florence) - [Flights from Kansas City (MCI) to Florence (FLO) ](https://www.expedia.com/lp/flights/mci/flo/kansas-city-to-florence) - [Flights from Providence (PVD) to Florence (FLO) ](https://www.expedia.com/lp/flights/pvd/flo/providence-to-florence) - [Flights from El Paso (ELP) to Florence (FLO) ](https://www.expedia.com/lp/flights/elp/flo/el-paso-to-florence) - [Flights from Cincinnati (CVG) to Florence (FLO) ](https://www.expedia.com/lp/flights/cvg/flo/cincinnati-to-florence) - [Flights from West Palm Beach (PBI) to Florence (FLO) ](https://www.expedia.com/lp/flights/pbi/flo/west-palm-beach-to-florence) - [Flights from New Orleans (MSY) to Florence (FLO) ](https://www.expedia.com/lp/flights/msy/flo/new-orleans-to-florence) - [Flights from Asheville (AVL) to Florence (FLO) ](https://www.expedia.com/lp/flights/avl/flo/asheville-to-florence) - [Flights from Gainesville (GNV) to Florence (FLO) ](https://www.expedia.com/lp/flights/gnv/flo/gainesville-to-florence) - [Flights from Missoula (MSO) to Florence (FLO) ](https://www.expedia.com/lp/flights/mso/flo/missoula-to-florence) - [Flights from Lancaster (LNS) to Florence (FLO) ](https://www.expedia.com/lp/flights/lns/flo/lancaster-to-florence) - [Flights from Nairobi (NBO) to Florence (FLO) ](https://www.expedia.com/lp/flights/nbo/flo/nairobi-to-florence) - [Flights from New Haven (HVN) to Florence (FLO) ](https://www.expedia.com/lp/flights/hvn/flo/new-haven-to-florence) - [Flights from Tallahassee (TLH) to Florence (FLO) ](https://www.expedia.com/lp/flights/tlh/flo/tallahassee-to-florence) - [Flights from Harrisburg (MDT) to Florence (FLO) ](https://www.expedia.com/lp/flights/mdt/flo/harrisburg-to-florence) - [Flights from Washington (IAD) to Florence (FLO) ](https://www.expedia.com/lp/flights/iad/flo/washington-to-florence) - [Flights from Boise (BOI) to Florence (FLO) ](https://www.expedia.com/lp/flights/boi/flo/boise-to-florence) - [Flights from Allentown (ABE) to Florence (FLO) ](https://www.expedia.com/lp/flights/abe/flo/allentown-to-florence) - [Flights from Salt Lake City (SLC) to Florence (FLO) ](https://www.expedia.com/lp/flights/slc/flo/salt-lake-city-to-florence) - [Flights from Montgomery (MGM) to Florence (FLO) ](https://www.expedia.com/lp/flights/mgm/flo/montgomery-to-florence) - [Flights from Eugene (EUG) to Florence (FLO) ](https://www.expedia.com/lp/flights/eug/flo/eugene-to-florence) - [Flights from Fayetteville (FAY) to Florence (FLO) ](https://www.expedia.com/lp/flights/fay/flo/fayetteville-to-florence) - [Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Florence.d6162127.Vacation-Attraction) - [Florence Museum ](https://www.expedia.com/Florence-Museum-Florence.d6162137.Vacation-Attraction) - [Car rentals near Mcleod Regional Medical Center ](https://www.expedia.com/Car-Rentals-In-Mcleod-Regional-Medical-Center.d6162127.Car-Rental-Guide) - [Hertz Rental Cars in Florence Regional ](https://www.expedia.com/Hertz-Car-Rentals-In-Florence-Regional.d6027805-c40.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Florence Regional ](https://www.expedia.com/Avis-Car-Rentals-In-Florence-Regional.d6027805-c41.Car-Rental-Guide-Suppliers) - [Car rental Florence Airport (FLO) ](https://www.expedia.com/Car-Rentals-In-Florence-Regional.d6027805.Car-Rental-Guide) - [Budget Rental Cars in Florence Regional ](https://www.expedia.com/Budget-Car-Rentals-In-Florence-Regional.d6027805-c39.Car-Rental-Guide-Suppliers)