Title: The Best 2 Star Hotels in Florence, SC from $57 | Expedia.com [Florence Travel Guide](https://expedia.com/Florence.dx1221)[Hotels in Florence](https://expedia.com/Florence-Hotels.d1221.Travel-Guide-Hotels)[Vacation Rentals in Florence](https://expedia.com/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.com/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Things to do in Florence](https://expedia.com/Things-To-Do-In-Florence.d1221.Travel-Guide-Activities)[Car Rentals in Florence](https://expedia.com/Car-Rentals-In-Florence.d1221.Car-Rental-Guide)[Florence Vacation Packages](https://expedia.com/Florence.d1221.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Florence 2 Star Hotels Tonight [Feb 15 - Feb 16](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-02-15&endDate=2026-02-16&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 16 - Feb 17](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-02-16&endDate=2026-02-17&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-02-20&endDate=2026-02-22&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-02-27&endDate=2026-03-01&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Florence 2-star hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking | 1 bedroom, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/8a1b879d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking (1st Floor) | Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/f9691b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) Florence 8.6/10 Excellent (2,568 reviews) "Clean rooms, good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Suman $63 nightly $70 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0c64863b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC [](https://www.expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) Florence 9.0/10 Wonderful (2,239 reviews) "Room was clean, staff friendly, and the includes breakfast was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha $85 nightly $95 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fefdad76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a63ff680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/6df606aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area [](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) Florence 9.2/10 Wonderful (1,227 reviews) "Room was very nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew $98 nightly $110 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/dc8d999b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/f82666ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/852cfc33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center [](https://www.expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) Florence 7.8/10 Good (1,265 reviews) "Quiet clean and many options local for food etc Good for a night or two stay Bed was comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Louis $85 nightly $95 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/995e3ecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/59604fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/a2c60bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-North-I-95 [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) Florence 9.0/10 Wonderful (863 reviews) "The employees were so nice!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ron $102 nightly $114 total Feb 24 - Feb 25 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Premium bedding, pillowtop beds, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/1000000/10000/500/455/ef1db617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/500/455/5074ad24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/500/455/be7cdd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/455/af3985b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Inn [](https://www.expedia.com/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) Florence 7.8/10 Good (1,001 reviews) "Front desk staff was great and very friendly! Made for a smooth check-in!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patric $84 nightly $94 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/3ba2ede7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/1a4a47d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/dab62d55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence/I-95 North [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) Florence 6.8/10 (1,006 reviews) "Great room and reasonable price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hattab $58 nightly $65 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/76254b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/edb6be2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Accessible, Non Smoking (Roll-In Shower) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/2b946657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/31819118.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Dillon, SC [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Dillon.h12827.Hotel-Information) Dillon 6.4/10 (1,005 reviews) "Nice rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaqwonda $51 nightly $57 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Dillon.h12827.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/8339db76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/20f68e84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/d5b1a48f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Florence I-95 [](https://www.expedia.com/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) Florence 8.4/10 Very Good (1,000 reviews) "We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marita $97 nightly $108 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/06692e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/7e5ec8df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/w6955h4642x8y0-4ae289f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/05885eec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at the Crossroads [](https://www.expedia.com/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) Lake City 9.4/10 Exceptional (854 reviews) "We always enjoy our stay at the Inn. Food at the Bistro never disappoints and the bartender is always friendly and remembers us from past visits. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara $120 nightly $135 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1f011cac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d1f8ba02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d2976b97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence Near Civic Center [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) Florence 6.8/10 (1,002 reviews) "Love this room dearly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andre $66 nightly $74 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/ffaddd2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/83cb7582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/689a1cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9f09eded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) Florence 8.6/10 Excellent (1,008 reviews) "Friendly staff, quick check in, nice lobby" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer $118 nightly $132 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/6cda2c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5a5d3612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/7942388a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Florence I-20 [](https://www.expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) Florence 9.2/10 Wonderful (587 reviews) "Friendly staff, clean and comfortable room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) craig $110 nightly $123 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/c68ab7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/d963a865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/67a43c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/434898b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Florence I-95 [](https://www.expedia.com/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) Florence 8.4/10 Very Good (1,002 reviews) "Great accommodations and courteous staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie $97 nightly $108 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/9c0353ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/07b3e89f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/fb5956cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Accessible (Communications, Mobility, Access Tub) | In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/cfd93cd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) Florence 9.2/10 Wonderful (1,001 reviews) "Clean rooms and nice breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adam $116 nightly $130 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/114000000/113640000/113638700/113638614/9722c1f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/114000000/113640000/113638700/113638614/c5af42dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/114000000/113640000/113638700/113638614/bc0d675a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible, Non Smoking | Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/114000000/113640000/113638700/113638614/62a64c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Sumter Near Shaw Afb [](https://www.expedia.com/Sumter-Hotels-Woodspring-Suites-Sumter-Near-Shaw-Afb.h113638614.Hotel-Information) Sumter 8.2/10 Very Good (166 reviews) "Cleanliness was a definite but the hotel was very generic. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stevenson $104 nightly $116 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sumter-Hotels-Woodspring-Suites-Sumter-Near-Shaw-Afb.h113638614.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/900000/899000/898902/77d2b021.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, towels](https://images.trvl-media.com/lodging/1000000/900000/899000/898902/7fa5ab06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/899000/898902/b2fc1e47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/900000/899000/898902/9a99b1eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Florence, SC [](https://www.expedia.com/Florence-Hotels-Motel-6-Florence.h898902.Hotel-Information) Florence 6.4/10 (658 reviews) "it a good hotel it's a good hotel good people and manager is a good person" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Travis $56 nightly $63 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Motel-6-Florence.h898902.Hotel-Information) ![Room, 1 Queen Bed, Accessible, Non Smoking | In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/93db4fd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/cbd95825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/73965d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) Florence 6.8/10 (1,005 reviews) "Friendly staff, clean room, very comfortable bed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Willie $55 nightly $62 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Blackout drapes, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/ae830b76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, shampoo, toilet paper](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/33c86cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/4165fb4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/bbdb0658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Sumter [](https://www.expedia.com/Sumter-Hotels-Red-Roof-Inn-Sumter.h1281499.Hotel-Information) Sumter 6.8/10 (282 reviews) "very comfortable and clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vladimir $90 nightly $101 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Sumter-Hotels-Red-Roof-Inn-Sumter.h1281499.Hotel-Information) ![Iron/ironing board, free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/110000/105100/105003/16359541.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/105100/105003/b56692a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/105100/105003/ad1344a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/105100/105003/eade505e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Dillon [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-Dillon.h105003.Hotel-Information) Dillon 5.4/10 (875 reviews) "Really enjoyed my stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Josh $54 nightly $60 total Mar 18 - Mar 19 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-Dillon.h105003.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Florence-Hotels.s20-0-d1221.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Florence-Hotels.s20-0-d1221.Travel-Guide-Filter-Hotels) ## Explore similar 3-star hotels Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Florence. ![La Quinta Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### La Quinta Inn & Suites by Wyndham Florence 2123 W Lucas St Florence SC $95 nightly $106 total Feb 22 - Feb 23 Total with taxes and fees 7.8/10 Good! (1,681 reviews) [](https://expedia.com/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hyatt Place Florence Downtown 100 East Evans Street Florence Florence SC $100 nightly $112 total Feb 23 - Feb 24 Total with taxes and fees 8.8/10 Excellent! (1,000 reviews) [](https://expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![TownePlace Suites by Marriott Florence](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### TownePlace Suites by Marriott Florence 2650 Hospitality Boulevard Florence SC $105 nightly $118 total Feb 16 - Feb 17 Total with taxes and fees 8.8/10 Excellent! (755 reviews) [](https://expedia.com/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) Still don't see what you're looking for? [See all properties in Florence.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F16%2F2026&endDate=2%2F17%2F2026®ionId=1221&star=20) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F16%2F2026&endDate=2%2F17%2F2026®ionId=1221&star=20&star=20&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F16%2F2026&endDate=2%2F17%2F2026®ionId=1221&star=20&star=20&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F16%2F2026&endDate=2%2F17%2F2026®ionId=1221&star=20&star=20&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F16%2F2026&endDate=2%2F17%2F2026®ionId=1221&star=20&star=20&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F16%2F2026&endDate=2%2F17%2F2026®ionId=1221&star=20&star=20&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Florence and related destinations - Florence - Mahwah - Nanuet - Katy - Texarkana - Rolla Stroll through the West Broad Street Historic District to soak up local history before exploring the Florence Museum's diverse exhibits. Catch a show at the Florence Civic Center or hunt for bargains at Magnolia Mall for a taste of modern entertainment. [See all hotels in Florence](https://www.expedia.com/Hotel-Search?startDate=2026-03-01&endDate=2026-03-02&adults=2®ionId=1221) ![Wyche Pavilion Greenville South Carolina ](https://images.trvl-media.com/place/1221/22638cec-95e4-4f53-af15-3963f8a47f19.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top Florence Hotel Reviews ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "Room was great and clean, staff friendly and helpful. " [](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Microtel Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/cbd95825_y.jpg) ### Microtel Inn & Suites by Wyndham Florence 10/10 Excellent "The staff was amazing. The front receptionist went above and beyond to help us out. Definitely will stay again. " [](https://expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/b1bbd639_y.jpg) ### Days Inn by Wyndham Florence/I-95 North 10/10 Excellent "Great room and reasonable price " [](https://expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ## Price trends for properties with 2 Stars in Florence | Less expensive | More expensive | Next month | | -------------- | -------------- | ---------- | | February | March | $92 | | Month | Price | | --------- | ----- | | January | $85 | | February | $80 | | March | $92 | | April | $84 | | May | $84 | | June | $85 | | July | $85 | | August | $85 | | September | $91 | | October | $86 | | November | $85 | | December | $85 | Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed properties with 2 stars in Florence. Select dates and complete search for nightly totals inclusive of taxes and fees. ## Find out more about Florence When it's time for an affordable family getaway, a weekend away with your special someone, or a simple solo escape, book a Florence 2 Star Hotel. To find out why this is a region becomes more popular each day, enjoy top-notch amenities and explore interesting attractions. Find a new favorite bakery or plaza nearby and while away the day, or stay on your feet visiting top attractions that draw several of devoted visitors to Florence. You're about to find out why locals and travelers alike love this place. ### The Right Hotel at the Ideal Price 2 Star hotels are in high demand in Florence. You'll find the best deals right here, so book early and save on a great getaway. Thanks to several convenient locations and comfortable amenities, you'll find accommodation that suits your vacation style. Be one of the first travelers to write a review and share your experience. So, savor the comfort of a well-kept room and attentive hospitality. With our travel deals, the world is wide open to you one hotel at a time, and the journey starts in Florence. ### Book Your Two-Star 2 Star Hotel Today! Plan your trip to Florence now with Expedia's easy online travel booking and start relaxing before you even leave the house. If you need a break from the crowds, you may find that this region offers just the reprieve you've been looking for. Take advantage of the 2 Star Hotel availability and easy-going atmosphere. ## Frequently asked questions ### How much does it cost to stay in a 2-star hotel in Florence? ### What are the most highly rated Florence 2-star hotels? > Another excellent choice is the [Hampton Inn & Suites Florence Center](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information), which also enjoys a great rating of 9.2 from travelers. This property features spacious rooms equipped with kitchen amenities like microwaves and refrigerators, ideal for families who appreciate the ease of preparing snacks or light meals. The inviting space and attentive service make it a great base for exploring the area or enjoying quality time with loved ones. > > > If you're traveling for business or as a couple, the [Comfort Inn & Suites](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information), rated the same at 9.2, offers fantastic fitness facilities to keep you active during your stay. Its accessible fitness center allows you to maintain your routine, while the hotel's comfortable ambiance provides a peaceful retreat after a busy day. ### Are there 2-star Florence hotels that offer free breakfast? > Equally appealing is the Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center, which also enjoys a stellar rating of 9.2\. This hotel features a delicious free buffet breakfast, ensuring that travelers can fuel up for their day of activities. > > > Lastly, the [Hampton Inn & Suites Florence Center](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) matches the quality and service of its counterparts, with the same commendable review score of 9.2\. Here, you can enjoy a complimentary breakfast while basking in the comfort of a well-appointed room. ### What 2-star hotels in Florence have free parking? > Equally appealing is the [Hampton Inn & Suites Florence Center](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information), which shares the same stellar rating of 9.2\. This hotel also provides complimentary self-parking, along with accessible parking options, making it great for families or travelers with special needs. Guests appreciate the inviting environment and attentive service, which enhance their overall experience. > > > Another great choice is the [Hampton Inn & Suites Florence-North-I-95](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information), rated at 9.0\. Like its counterparts, this hotel offers free self-parking and accessible parking, ensuring that convenience is at the forefront of your stay. With its comfortable accommodations and friendly staff, it's an ideal option for those seeking quality and ease during their travels. ### Are there family-friendly 2-star hotels in Florence? > Similarly, the [Comfort Inn & Suites](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) also shines with a stellar rating of 9.2\. It provides a refreshing pool, superb for cooling off after a day of exploring, and family-friendly conveniences like a microwave and daily housekeeping to keep your stay carefree and enjoyable. > > > Another great option is the [Hampton Inn & Suites Florence Center](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information), which matches the 9.2 rating and enhances the family experience with both a pool and highchairs available for the little ones. With additional amenities such as a kitchen and microwave, this hotel makes it easy to prepare snacks or meals, adding to your convenience during your stay. ### Are there any 2-star Florence hotels with a pool? > The Holiday Inn Express & Suites Florence I-95 & I-20 Civic Center by IHG also boasts an excellent customer review score of 9.2 and features an inviting indoor pool, which is ideal for families who want to enjoy some splash time regardless of the weather outside. > > > Additionally, the [Hampton Inn & Suites Florence Center](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information), with the same great rating of 9.2, offers both an outdoor pool and a friendly feel, making it a fantastic choice for those traveling with children. ### Can I find pet-friendly 2-star hotels in Florence? > Another excellent choice is the [Hampton Inn & Suites Florence Center](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information), which also boasts a stellar rating of 9.2\. This hotel is pet-friendly, accommodating both dogs and cats, and provides a inviting space superb for families seeking convenience and comfort. > > > Lastly, the [Park Inn by Radisson Florence, SC](https://www.expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information), with a traveler review rating of 9.0, offers a similarly pet-friendly environment. Alongside welcoming pets, this hotel enhances your stay with thoughtful touches like food and water bowls, making it an ideal option for those traveling with their four-legged friends. ### What is the difference between a 2-star Florence hotel and a 3-star hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Station ](https://www.expedia.com/Florence-Station-Hotels.d6195493.Travel-Guide-Hotels) - [Hotels near Florence Museum ](https://www.expedia.com/Florence-Museum-Hotels.0-l6162137-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence National Cemetery ](https://www.expedia.com/Florence-National-Cemetery-Hotels.0-l553248621532657341-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Regional ](https://www.expedia.com/Florence-Regional-Airport-Hotels.0-aFLO-0.Travel-Guide-Filter-Hotels) - 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[Flights from Hartford (BDL) to Florence (FLO) ](https://www.expedia.com/lp/flights/bdl/flo/hartford-to-florence) - [Flights from Tampa (TPA) to Florence (FLO) ](https://www.expedia.com/lp/flights/tpa/flo/tampa-to-florence) - [Flights from Greenville (GSP) to Florence (FLO) ](https://www.expedia.com/lp/flights/gsp/flo/greenville-to-florence) - [Flights from Dallas (DFW) to Florence (FLO) ](https://www.expedia.com/lp/flights/dfw/flo/dallas-to-florence) - [Flights from Rochester (ROC) to Florence (FLO) ](https://www.expedia.com/lp/flights/roc/flo/rochester-to-florence) - [Flights from Orlando (MCO) to Florence (FLO) ](https://www.expedia.com/lp/flights/mco/flo/orlando-to-florence) - [Flights from Oklahoma City (OKC) to Florence (FLO) ](https://www.expedia.com/lp/flights/okc/flo/oklahoma-city-to-florence) - [Flights from Huntsville (HSV) to Florence (FLO) ](https://www.expedia.com/lp/flights/hsv/flo/huntsville-to-florence) - [Flights from Los Angeles (LAX) to Florence (FLO) ](https://www.expedia.com/lp/flights/lax/flo/los-angeles-to-florence) - [Flights from Phoenix (PHX) to Florence (FLO) ](https://www.expedia.com/lp/flights/phx/flo/phoenix-to-florence) - [Flights from Fort Lauderdale (FLL) to Florence (FLO) ](https://www.expedia.com/lp/flights/fll/flo/fort-lauderdale-to-florence) - [Flights from Miami (MIA) to Florence (FLO) ](https://www.expedia.com/lp/flights/mia/flo/miami-to-florence) - [Flights from Wilmington (ILM) to Florence (FLO) ](https://www.expedia.com/lp/flights/ilm/flo/wilmington-to-florence) - [Flights from Raleigh (RDU) to Florence (FLO) ](https://www.expedia.com/lp/flights/rdu/flo/raleigh-to-florence) - [Flights from Savannah (SAV) to Florence (FLO) ](https://www.expedia.com/lp/flights/sav/flo/savannah-to-florence) - [Flights from Memphis (MEM) to Florence (FLO) ](https://www.expedia.com/lp/flights/mem/flo/memphis-to-florence) - [Flights from San Diego (SAN) to Florence (FLO) ](https://www.expedia.com/lp/flights/san/flo/san-diego-to-florence) - [Flights from Sarasota (SRQ) to Florence (FLO) ](https://www.expedia.com/lp/flights/srq/flo/sarasota-to-florence) - [Flights from Denver (DEN) to Florence (FLO) ](https://www.expedia.com/lp/flights/den/flo/denver-to-florence) - [Flights from Seattle (SEA) to Florence (FLO) ](https://www.expedia.com/lp/flights/sea/flo/seattle-to-florence) - [Flights from Pittsburgh (PIT) to Florence (FLO) ](https://www.expedia.com/lp/flights/pit/flo/pittsburgh-to-florence) - [Flights from Detroit (DTW) to Florence (FLO) ](https://www.expedia.com/lp/flights/dtw/flo/detroit-to-florence) - [Flights from Albany (ALB) to Florence (FLO) ](https://www.expedia.com/lp/flights/alb/flo/albany-to-florence) - [Flights from Buffalo (BUF) to Florence (FLO) ](https://www.expedia.com/lp/flights/buf/flo/buffalo-to-florence) - [Flights from Lexington (LEX) to Florence (FLO) ](https://www.expedia.com/lp/flights/lex/flo/lexington-to-florence) - [Flights from Louisville (SDF) to Florence (FLO) ](https://www.expedia.com/lp/flights/sdf/flo/louisville-to-florence) - [Flights from Cleveland (CLE) to Florence (FLO) ](https://www.expedia.com/lp/flights/cle/flo/cleveland-to-florence) - [Flights from Austin (AUS) to Florence (FLO) ](https://www.expedia.com/lp/flights/aus/flo/austin-to-florence) - [Flights from San Francisco (SFO) to Florence (FLO) ](https://www.expedia.com/lp/flights/sfo/flo/san-francisco-to-florence) - [Flights from Greensboro (GSO) to Florence (FLO) ](https://www.expedia.com/lp/flights/gso/flo/greensboro-to-florence) - [Flights from Columbus (CMH) to Florence (FLO) ](https://www.expedia.com/lp/flights/cmh/flo/columbus-to-florence) - [Flights from Richmond (RIC) to Florence (FLO) ](https://www.expedia.com/lp/flights/ric/flo/richmond-to-florence) - [Flights from Augusta (AGS) to Florence (FLO) ](https://www.expedia.com/lp/flights/ags/flo/augusta-to-florence) - [Flights from Tucson (TUS) to Florence (FLO) ](https://www.expedia.com/lp/flights/tus/flo/tucson-to-florence) - [Flights from Birmingham (BHM) to Florence (FLO) ](https://www.expedia.com/lp/flights/bhm/flo/birmingham-to-florence) - [Flights from Syracuse (SYR) to Florence (FLO) ](https://www.expedia.com/lp/flights/syr/flo/syracuse-to-florence) - [Flights from Chattanooga (CHA) to Florence (FLO) ](https://www.expedia.com/lp/flights/cha/flo/chattanooga-to-florence) - [Flights from Dayton (DAY) to Florence (FLO) ](https://www.expedia.com/lp/flights/day/flo/dayton-to-florence) - [Flights from Indianapolis (IND) to Florence (FLO) ](https://www.expedia.com/lp/flights/ind/flo/indianapolis-to-florence) - [Flights from Norfolk (ORF) to Florence (FLO) ](https://www.expedia.com/lp/flights/orf/flo/norfolk-to-florence) - [Flights from Little Rock (LIT) to Florence (FLO) ](https://www.expedia.com/lp/flights/lit/flo/little-rock-to-florence) - [Flights from Minneapolis (MSP) to Florence (FLO) ](https://www.expedia.com/lp/flights/msp/flo/minneapolis-to-florence) - [Flights from Knoxville (TYS) to Florence (FLO) ](https://www.expedia.com/lp/flights/tys/flo/knoxville-to-florence) - [Flights from Newburgh (SWF) to Florence (FLO) ](https://www.expedia.com/lp/flights/swf/flo/newburgh-to-florence) - [Flights from London (LHR) to Florence (FLO) ](https://www.expedia.com/lp/flights/lhr/flo/london-to-florence) - [Flights from Daytona Beach (DAB) to Florence (FLO) ](https://www.expedia.com/lp/flights/dab/flo/daytona-beach-to-florence) - [Flights from Milwaukee (MKE) to Florence (FLO) ](https://www.expedia.com/lp/flights/mke/flo/milwaukee-to-florence) - [Flights from Sacramento (SMF) to Florence (FLO) ](https://www.expedia.com/lp/flights/smf/flo/sacramento-to-florence) - [Flights from Colorado Springs (COS) to Florence (FLO) ](https://www.expedia.com/lp/flights/cos/flo/colorado-springs-to-florence) - [Flights from Kansas City (MCI) to Florence (FLO) ](https://www.expedia.com/lp/flights/mci/flo/kansas-city-to-florence) - [Flights from Providence (PVD) to Florence (FLO) ](https://www.expedia.com/lp/flights/pvd/flo/providence-to-florence) - [Flights from El Paso (ELP) to Florence (FLO) ](https://www.expedia.com/lp/flights/elp/flo/el-paso-to-florence) - [Flights from Cincinnati (CVG) to Florence (FLO) ](https://www.expedia.com/lp/flights/cvg/flo/cincinnati-to-florence) - [Flights from West Palm Beach (PBI) to Florence (FLO) ](https://www.expedia.com/lp/flights/pbi/flo/west-palm-beach-to-florence) - [Flights from New Orleans (MSY) to Florence (FLO) ](https://www.expedia.com/lp/flights/msy/flo/new-orleans-to-florence) - [Flights from Asheville (AVL) to Florence (FLO) ](https://www.expedia.com/lp/flights/avl/flo/asheville-to-florence) - [Flights from Gainesville (GNV) to Florence (FLO) ](https://www.expedia.com/lp/flights/gnv/flo/gainesville-to-florence) - [Flights from Missoula (MSO) to Florence (FLO) ](https://www.expedia.com/lp/flights/mso/flo/missoula-to-florence) - [Flights from Lancaster (LNS) to Florence (FLO) ](https://www.expedia.com/lp/flights/lns/flo/lancaster-to-florence) - [Flights from Nairobi (NBO) to Florence (FLO) ](https://www.expedia.com/lp/flights/nbo/flo/nairobi-to-florence) - [Flights from New Haven (HVN) to Florence (FLO) ](https://www.expedia.com/lp/flights/hvn/flo/new-haven-to-florence) - [Flights from Tallahassee (TLH) to Florence (FLO) ](https://www.expedia.com/lp/flights/tlh/flo/tallahassee-to-florence) - [Flights from Harrisburg (MDT) to Florence (FLO) ](https://www.expedia.com/lp/flights/mdt/flo/harrisburg-to-florence) - [Flights from Washington (IAD) to Florence (FLO) ](https://www.expedia.com/lp/flights/iad/flo/washington-to-florence) - [Flights from Boise (BOI) to Florence (FLO) ](https://www.expedia.com/lp/flights/boi/flo/boise-to-florence) - [Flights from Allentown (ABE) to Florence (FLO) ](https://www.expedia.com/lp/flights/abe/flo/allentown-to-florence) - [Flights from Salt Lake City (SLC) to Florence (FLO) ](https://www.expedia.com/lp/flights/slc/flo/salt-lake-city-to-florence) - [Flights from Montgomery (MGM) to Florence (FLO) ](https://www.expedia.com/lp/flights/mgm/flo/montgomery-to-florence) - [Flights from Eugene (EUG) to Florence (FLO) ](https://www.expedia.com/lp/flights/eug/flo/eugene-to-florence) - [Flights from Fayetteville (FAY) to Florence (FLO) ](https://www.expedia.com/lp/flights/fay/flo/fayetteville-to-florence) - [Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Florence.d6162127.Vacation-Attraction) - [Florence Museum ](https://www.expedia.com/Florence-Museum-Florence.d6162137.Vacation-Attraction) - [Car rentals near Mcleod Regional Medical Center ](https://www.expedia.com/Car-Rentals-In-Mcleod-Regional-Medical-Center.d6162127.Car-Rental-Guide) - [Hertz Rental Cars in Florence Regional ](https://www.expedia.com/Hertz-Car-Rentals-In-Florence-Regional.d6027805-c40.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Florence Regional ](https://www.expedia.com/Avis-Car-Rentals-In-Florence-Regional.d6027805-c41.Car-Rental-Guide-Suppliers) - [Car rental Florence Airport (FLO) ](https://www.expedia.com/Car-Rentals-In-Florence-Regional.d6027805.Car-Rental-Guide) - [Budget Rental Cars in Florence Regional ](https://www.expedia.com/Budget-Car-Rentals-In-Florence-Regional.d6027805-c39.Car-Rental-Guide-Suppliers)