Beginning of main content

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Recently booked Florence hotels

Country Inn & Suites by Radisson, Florence, SC
3.0 out of 5.0
Last booking: 1 hour ago
Courtyard by Marriott Florence
3.0 out of 5.0
Last booking: 1 hour ago
Hampton Inn Suites FlorenceNorthI95
0.0 out of 5.0
Last booking: 1 hour ago
Quality Inn And Suites Civic
2.5 out of 5.0
Last booking: 3 hours ago
Baymont Inn & Suites Florence
2.0 out of 5.0
Last booking: 4 hours ago
Econo Lodge
2.0 out of 5.0
Last booking: 4 hours ago
La Quinta Inn & Suites Florence
3.0 out of 5.0
Last booking: 15 hours ago
Hotel Florence, an Ascend Hotel Collection Member
3.5 out of 5.0
Last booking: 15 hours ago
Days Inn Florence Near Civic Center
2.5 out of 5.0
Last booking: 15 hours ago

Florence Best Western Hotel Information

You're the type of jet-setter that always knows what they deserve: all the quality and comfort that Best Western provides. For your vacation to the city, you want to save the surprises for exciting things, like visiting a new restaurant or hidden activity, not your hotel brand. Work with Expedia to reserve Best Western hotels in South Carolina Midlands, and that's one more thing you know is taken care of.

Expedia is known for having a diverse offering of hotels globally, so if you're looking for your favorite company, you will definitely find it here. We have 2 options for you in Florence, so you'll have tons of choices, in a manageable list. We think you will see all the service you have come to expect, plus low prices. And while Best Western is popular for their hotels, they also have fabulous motels, depending on your city of choice. It's time to research all there is to know, when you search with Expedia.

Expedia also posts dependable comments for your specific accommodation, so you know just what to expect before you get there. Yes, we've made sure that our reviewers aren't just anonymous posters, so you know they are for real. Guests gave an average overall rating of 4, so you can see why Best Western hotels and motels are so in demand.And with an average service rating of 4.2, you know the staff will be welcoming and informed.

More and more travelers are visiting this year, so come see what all the fuss is about! Get your spot early so you're certain to get in on the fun. No matter when you decide to make new memories, you'll always discover the top offering of Best Western hotels right here on Expedia. There are many great extras heading at you,book now. Florence is calling to you. It's time you experienced it for yourself, in style.