Title: 10 Best Motels in New Madrid: Find Cheap Motels in New Madrid, MO 2026 - Expedia.com [New Madrid Travel Guide](https://expedia.com/New-Madrid.dx3000445315)[Hotels in New Madrid](https://expedia.com/New-Madrid-Hotels.d3000445315.Travel-Guide-Hotels)[Vacation Rentals in New Madrid](https://expedia.com/New-Madrid-Vacation-Rentals.d3000445315.Travel-Guide-VacationRentals)[Flights to New Madrid](https://expedia.com/Cheap-Flights-To-New-Madrid.d3000445315.Travel-Guide-Flights)[Car Rentals in New Madrid](https://expedia.com/Car-Rentals-In-New-Madrid.d3000445315.Car-Rental-Guide)[New Madrid Vacation Packages](https://expedia.com/New-Madrid.d3000445315.Destination-Travel-Guides) ![Mississippi River Walk at New Madrid. A magnificent view of the Mississippi river from atop of the levee. A steamboat is docked down river. . ](https://images.trvl-media.com/place/3000445315/970b11d9-266d-426a-9577-5e745e0939b7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/3000445315/970b11d9-266d-426a-9577-5e745e0939b7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=3000445315&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=3000445315&startDate=2026-04-17&endDate=2026-04-19&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=3000445315&startDate=2026-05-01&endDate=2026-05-03&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=3000445315&startDate=2026-05-29&endDate=2026-05-31&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for New Madrid motels ![Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/1d8642af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/a77daa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/91bb8871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Orleans Inn Portageville [](https://www.expedia.com/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) Portageville 8.0/10 Very Good (756 reviews) "The staff was great very helpful and friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Javier $52 nightly $56 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ![Standard Room, 2 Double Beds, Non Smoking | Blackout drapes, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/543bd231.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/60633b31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/45782657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Handicap Room | Blackout drapes, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/6128b6d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reelfoot Lake Inn [](https://www.expedia.com/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information) Tiptonville 7.2/10 Good (476 reviews) "Ok one night stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David $70 nightly $80 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-13&endDate=2026-04-14®ionId=3000445315&adults=2&lodging=MOTEL&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FNew-Madrid-Motels.d3000445315-aaMotels.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FNew-Madrid-Motels.d3000445315-aaMotels.Travel-Guide-Accommodation) ## Top New Madrid Hotel Reviews ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "Yes" [](https://expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54_y.jpg) ### Fairfield Inn & Suites by Marriott Sikeston 8/10 Good "The hotel is beautiful and absolutely gorgeous!! Brand new. Very clean and the staff were all very friendly and welcoming and I mean All of the staff down to housekeeping. I would have given 5 stars but the pool heater wasn’t working and it was a bit too cold to swim so that was a little disappointing. Id definitely return again 😊" [](https://expedia.com/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Lakeside View Lodge overlooking beautiful Reelfoot Lake](https://images.trvl-media.com/lodging/91000000/90200000/90191600/90191536/2b6c083c_y.jpg) ### Lakeside View Lodge overlooking beautiful Reelfoot Lake 8/10 Good "Host's were great. Very attentive. Everything "mechanical" worked just fine." [](https://expedia.com/Hornbeak-Hotels-Lakeside-View-Lodge-Overlooking-Beautiful-Reelfoot-Lake.h90191536.Hotel-Information) ![New Orleans Inn Portageville ](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936_y.jpg) ### New Orleans Inn Portageville 4/10 Poor "Parking was fine, when I pulled back the sheets on the bed it had human hair that's wasn't mine, sheets had what looked like rust spots on them, TV was in Spanish I didn't knew how to change it. Bed side drawer had trash in it. Bed were very hard woke up w back hurting." [](https://expedia.com/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ![Great location just across the street from Reelfoot Lake close to boat ramps](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/71b3c54d_y.jpg) ### Great location just across the street from Reelfoot Lake close to boat ramps 10/10 Excellent "This was really nice place across the street from the lake. There was a ramp launch really close. There are several other locations on different portions of the lake. The host was responsive to messages. There is a garage and cleaning station behind the house. The house have everything from coffee maker, kureg, deep fryer, air fryer. They even provided coffee filters, packets of coffee, creamer and sugar. No need to bring anything extra. It was nice having a washer and dryer. Would recommend this VRBO.." [](https://expedia.com/Hornbeak-Hotels-Great-Location-Just-Across-The-Street-From-Reelfoot-Lake-Close-To-Boat-Ramps.h89872735.Hotel-Information) ![Reelfoot Lake Inn](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/543bd231_y.jpg) ### Reelfoot Lake Inn 10/10 Excellent "The view of the lake is beautiful. It's right across the road. The manager and staff were very kind and set me up in the kind of room I requested. It had a microwave, refrigerator and coffee pot with the coffee. The bed was very comfortable and the air worked great. I would stay there again. " [](https://expedia.com/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information) ![Duck Hunting, Fishing or Relaxing Family Vacation](https://images.trvl-media.com/lodging/37000000/36090000/36089000/36088974/d93cc56b_y.jpg) ### Duck Hunting, Fishing or Relaxing Family Vacation 10/10 Excellent "Yes, it was very nice. Will be back for sure. View was awesome. The house was very nice and fully stocked." [](https://expedia.com/Hornbeak-Hotels-Duck-Hunting.h36088974.Hotel-Information) ![Come and relax at the Refuge at beautiful Reelfoot Lake!](https://images.trvl-media.com/lodging/84000000/83580000/83572000/83571978/0a58d14b_y.jpg) ### Come and relax at the Refuge at beautiful Reelfoot Lake! 10/10 Excellent "We loved The Refuge. We just came down for a weekend fishing trip with our boys, But it would be so perfect for someone who wants to come down with a group of friends, as there's plenty of twin beds. We loved it and would definitely stay again." [](https://expedia.com/Hornbeak-Hotels-Enjoy-Beautiful-Sunsets-At-The-HUT-2-At-Beautiful-Reelfoot-Lake.h83571978.Hotel-Information) ![Holiday Inn Express & Suites Sikeston Southwest by IHG](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a_y.jpg) ### Holiday Inn Express & Suites Sikeston Southwest by IHG 10/10 Excellent "Clean rooms, friendly staff and convenient location." [](https://expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ## Find out more about New Madrid ## New Madrid Motels information | Number of reviews | 1,232 | | ----------------- | -------- | | Accommodation | 2 Motels | | Lowest Price | $56 | | Highest Price | $80 | ## Frequently asked questions ### What is the nightly rate for a motel in New Madrid? ### Is it better to stay in a New Madrid motel or hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near New Madrid Historical Museum ](https://www.expedia.com/New-Madrid-Historical-Museum-Hotels.0-l553248621532655748-0.Travel-Guide-Filter-Hotels) - [Hotels near River Ridge Winery ](https://www.expedia.com/River-Ridge-Winery-Hotels.0-l553248621532655749-0.Travel-Guide-Filter-Hotels) - [Hotels near Hunter-Dawson State Historic Site ](https://www.expedia.com/Hunter-Dawson-State-Historic-Site-Hotels.0-l553248621532655794-0.Travel-Guide-Filter-Hotels) - [Lilbourn Hotels ](https://www.expedia.com/Lilbourn-Hotels.d553248634983590625.Travel-Guide-Hotels) - [Rv Parks in Marston ](https://www.expedia.com/Marston-RV-Parks.d55824-aaRVParks.Travel-Guide-Accommodation) - [Houseboats in Marston ](https://www.expedia.com/Marston-Houseboats.d55824-aaHouseboats.Travel-Guide-Accommodation) - [Marston Hotels ](https://www.expedia.com/Marston-Hotels.d55824.Travel-Guide-Hotels) - [Hotels near Marston Community Center ](https://www.expedia.com/Marston-Community-Center-Hotels.0-l553248622945532712-0.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in Marston ](https://www.expedia.com/Marston-Hotels-Hotels-With-Complimentary-Breakfast.0-0-d55824-tHotelswithComplimentaryBreakfast.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Marston ](https://www.expedia.com/5Star-Marston-Hotels.s50-0-d55824.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Marston ](https://www.expedia.com/Marston-Hotels-Pet-Friendly-Hotel.0-0-d55824-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Motels in Catron ](https://www.expedia.com/Catron-Motels.d3000349317-aaMotels.Travel-Guide-Accommodation) - [Catron Hotels ](https://www.expedia.com/Catron-Hotels.d3000349317.Travel-Guide-Hotels) - [5 Star Hotels in Catron ](https://www.expedia.com/5Star-Catron-Hotels.s50-0-d3000349317.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Catron ](https://www.expedia.com/4Star-Catron-Hotels.s40-0-d3000349317.Travel-Guide-Filter-Hotels) - [Matthews Hotels ](https://www.expedia.com/Matthews-Hotels.d553248634983428760.Travel-Guide-Hotels) - [Hotels near Big Oak Tree State Park ](https://www.expedia.com/Big-Oak-Tree-State-Park-Hotels.0-l553248621532655754-0.Travel-Guide-Filter-Hotels) - [Motels in Portageville ](https://www.expedia.com/Portageville-Motels.d183487-aaMotels.Travel-Guide-Accommodation) - [Portageville Hotels ](https://www.expedia.com/Portageville-Hotels.d183487.Travel-Guide-Hotels) - [Canalou Hotels ](https://www.expedia.com/Canalou-Hotels.d3000349311.Travel-Guide-Hotels) - [Lodges in East Prairie ](https://www.expedia.com/East-Prairie-Lodges.d3000349349-aaLodges.Travel-Guide-Accommodation) - [Motels in East Prairie ](https://www.expedia.com/East-Prairie-Motels.d3000349349-aaMotels.Travel-Guide-Accommodation) - [Vacation Homes in East Prairie ](https://www.expedia.com/East-Prairie-Private-Vacation-Homes.d3000349349-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [East Prairie Hotels ](https://www.expedia.com/East-Prairie-Hotels.d3000349349.Travel-Guide-Hotels) - [Parma Hotels ](https://www.expedia.com/Parma-Hotels.d553248634983328909.Travel-Guide-Hotels) - [Risco Hotels ](https://www.expedia.com/Risco-Hotels.d3000349516.Travel-Guide-Hotels) - [3 Star Hotels in Risco ](https://www.expedia.com/3Star-Risco-Hotels.s30-0-d3000349516.Travel-Guide-Filter-Hotels) - [Sikeston Hotels ](https://www.expedia.com/Sikeston-Hotels.d6058766.Travel-Guide-Hotels) - [Cabin Rentals in Sikeston ](https://www.expedia.com/Sikeston-Cabins.d6058766-aaCabins.Travel-Guide-Accommodation) - [B&B in Sikeston ](https://www.expedia.com/Sikeston-Bed-And-Breakfast.d6058766-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels near Central Park ](https://www.expedia.com/Central-Park-Hotels.0-l6305608-0.Travel-Guide-Filter-Hotels) - [Motels in Sikeston ](https://www.expedia.com/Sikeston-Motels.d6058766-aaMotels.Travel-Guide-Accommodation) - [Vacation Homes in Sikeston ](https://www.expedia.com/Sikeston-Private-Vacation-Homes.d6058766-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Cottages in Sikeston ](https://www.expedia.com/Sikeston-Cottages.d6058766-aaCottages.Travel-Guide-Accommodation) - [Hotels near Sikeston Depot Museum ](https://www.expedia.com/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Cheap-Hotels.0-0-d6058766-tCheapHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Pet-Friendly-Hotel.0-0-d6058766-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Hotels-With-Indoor-Pool.0-0-d6058766-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Hotels-With-Hot-Tubs.0-0-d6058766-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Casino Hotels in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Casino-Hotel.0-0-d6058766-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Hotels with Restaurants in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Hotels-With-Restaurants.0-0-d6058766-tHotelswithRestaurants.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Hotels-With-Kitchens.0-0-d6058766-tHotelswithKitchens.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Romantic-Hotel.0-0-d6058766-tRomanticHotel.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Sikeston ](https://www.expedia.com/5Star-Sikeston-Hotels.s50-0-d6058766.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Luxury-Hotel.0-0-d6058766-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Hotels with Bars in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Bar-Hotel.0-0-d6058766-tBarHotel.Travel-Guide-Filter-Hotels) - [Resorts & Hotels with Spas in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Spa-Hotel.0-0-d6058766-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Hotels-With-Adjoining-Rooms.0-0-d6058766-tHotelswithAdjoiningRooms.Travel-Guide-Filter-Hotels) - [Wyndham Hotels in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Wyndham-Hotels.0-0-d6058766--bWyndhamHotels.Travel-Guide-Filter-Hotels) - [Hotels with Laundry Facilities in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Hotels-With-Laundry-Facilities.0-0-d6058766-tHotelswithLaundryFacilities.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Wedding-Hotels.0-0-d6058766-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Historic Hotels in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Historic-Hotel.0-0-d6058766-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Family Hotels in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Family-Hotel.0-0-d6058766-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Gay friendly Hotels in Sikeston ](https://www.expedia.com/Sikeston-Hotels-LGBT-Welcoming-Hotel.0-0-d6058766-tLGBTWelcomingHotel.Travel-Guide-Filter-Hotels) - [Hotels with Suites in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Hotel-Suites.0-0-d6058766-tHotelSuites.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Couples-Resorts-Hotels.0-0-d6058766-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Hotels with an Outdoor Pool in Sikeston ](https://www.expedia.com/Sikeston-Hotels-Hotels-With-Outdoor-Pool.0-0-d6058766-tHotelswithOutdoorPool.Travel-Guide-Filter-Hotels) - [Flights from Howardville ](https://www.expedia.com/lp/flights/553248634983363505/flights-from-howardville) - [Flights from Lilbourn ](https://www.expedia.com/lp/flights/553248634983590625/flights-from-lilbourn) - [Flights to Portageville ](https://www.expedia.com/Cheap-Flights-To-Portageville.d183487.Travel-Guide-Flights) - [Flights from East Prairie ](https://www.expedia.com/lp/flights/3000349349/flights-from-east-prairie) - [Flights from Parma ](https://www.expedia.com/lp/flights/553248634983328909/flights-from-parma) - [Flights from Risco ](https://www.expedia.com/lp/flights/3000349516/flights-from-risco) - [Flights from Morehouse ](https://www.expedia.com/lp/flights/553248634983462037/flights-from-morehouse) - [Flights to Sikeston ](https://www.expedia.com/Cheap-Flights-To-Sikeston.d6058766.Travel-Guide-Flights) - [Flights from Sikeston ](https://www.expedia.com/lp/flights/6058766/flights-from-sikeston) - [New Madrid Historical Museum ](https://www.expedia.com/New-Madrid-Historical-Museum-New-Madrid.d553248621532655748.Vacation-Attraction) - [Hunter-Dawson State Historic Site ](https://www.expedia.com/Hunter-Dawson-State-Historic-Site-New-Madrid.d553248621532655794.Vacation-Attraction) - [Marston Community Center ](https://www.expedia.com/Marston-Community-Center-Marston.d553248622945532712.Vacation-Attraction) - [Visit Marston ](https://www.expedia.com/Marston.dx55824) - [Marston Vacations ](https://www.expedia.com/Marston.d55824.Destination-Travel-Guides) - [Visit Catron ](https://www.expedia.com/Catron.dx3000349317) - [Visit Canalou ](https://www.expedia.com/Canalou.dx3000349311) - [Visit Portageville ](https://www.expedia.com/Portageville.dx183487) - [Portageville Vacations ](https://www.expedia.com/Portageville.d183487.Destination-Travel-Guides) - [Visit East Prairie ](https://www.expedia.com/East-Prairie.dx3000349349) - [Visit Risco ](https://www.expedia.com/Risco.dx3000349516) - [Central Park ](https://www.expedia.com/Central-Park-Sikeston.d6305608.Vacation-Attraction) - [Sikeston Depot Museum ](https://www.expedia.com/Sikeston-Depot-Museum-Sikeston.d6305602.Vacation-Attraction) - [Visit Sikeston ](https://www.expedia.com/Sikeston.dx6058766) - [Car rentals near Howardville ](https://www.expedia.com/Car-Rentals-In-Howardville.d553248634983363505.Car-Rental-Guide) - [Car rentals near Marston ](https://www.expedia.com/Car-Rentals-In-Marston.d55824.Car-Rental-Guide) - [Car rentals near Catron ](https://www.expedia.com/Car-Rentals-In-Catron.d3000349317.Car-Rental-Guide) - [Convertible Car Rentals in Catron ](https://www.expedia.com/Convertible-Car-Rentals-In-Catron.d3000349317-tConvertible.Car-Rental-Guide-Class) - [Standard Car Rentals in Catron ](https://www.expedia.com/Standard-Car-Rentals-In-Catron.d3000349317-tStandard.Car-Rental-Guide-Class) - [Suv Car Rentals in Catron ](https://www.expedia.com/SUV-Car-Rentals-In-Catron.d3000349317-tSUV.Car-Rental-Guide-Class) - [Car rentals near Canalou ](https://www.expedia.com/Car-Rentals-In-Canalou.d3000349311.Car-Rental-Guide) - [Car rentals near Portageville ](https://www.expedia.com/Car-Rentals-In-Portageville.d183487.Car-Rental-Guide) - [Car rentals near East Prairie ](https://www.expedia.com/Car-Rentals-In-East-Prairie.d3000349349.Car-Rental-Guide) - [Car rentals near Risco ](https://www.expedia.com/Car-Rentals-In-Risco.d3000349516.Car-Rental-Guide) - [Car rentals near Baker ](https://www.expedia.com/Car-Rentals-In-Baker.d553248634983252914.Car-Rental-Guide) - [Enterprise Rental Cars in Sikeston ](https://www.expedia.com/Enterprise-Car-Rentals-In-Sikeston.d6058766-c15.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Sikeston ](https://www.expedia.com/Hertz-Car-Rentals-In-Sikeston.d6058766-c40.Car-Rental-Guide-Suppliers) - [Car rentals near Sikeston ](https://www.expedia.com/Car-Rentals-In-Sikeston.d6058766.Car-Rental-Guide) - [Van Car Rentals in Sikeston ](https://www.expedia.com/Van-Car-Rentals-In-Sikeston.d6058766-tVan.Car-Rental-Guide-Class) - [Budget Rental Cars in Sikeston ](https://www.expedia.com/Budget-Car-Rentals-In-Sikeston.d6058766-c39.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Sikeston ](https://www.expedia.com/Avis-Car-Rentals-In-Sikeston.d6058766-c41.Car-Rental-Guide-Suppliers) - [Marston Vacation Rentals ](https://www.expedia.com/Marston-Vacation-Rentals.d55824.Travel-Guide-VacationRentals) - [East Prairie Vacation Rentals ](https://www.expedia.com/East-Prairie-Vacation-Rentals.d3000349349.Travel-Guide-VacationRentals) - [Sikeston Vacation Rentals ](https://www.expedia.com/Sikeston-Vacation-Rentals.d6058766.Travel-Guide-VacationRentals)