A stone wall with a tower, palm trees, and calm water.

Southeast Jacksonville Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Oct 9 - Oct 11
In two months
Nov 20 - Nov 22
In three months
Dec 18 - Dec 20
In four months
Jan 15 - Jan 17

Our top choices for Southeast Jacksonville vacation rentals

A hotel room with a bed, a nightstand, and a window with curtains.

1. 1 Queen Bed | Smoking, Kitchen

1 Queen Bed | Smoking, Kitchen
Jacksonville
10.0 out of 10, Exceptional, (5 reviews)
$60 nightly
The price is $71
Sep 28 - Sep 29
Total with taxes and fees
1 Queen Bed | Smoking, Kitchen
A lobby with a sofa, armchair, and a table with a vase.

2. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Southside
9.4 out of 10, Exceptional, (33 reviews)
"Cool place to stay"
United States
Anonymous traveler
$55 nightly
The price is $62
Sep 28 - Sep 29
Total with taxes and fees
1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
A hotel with a large outdoor swimming pool, multiple balconies, and palm trees.

3. Spacious 1-BR, 2-King Beds, Near Mayo, Pool, Gym, Fast Wifi Workspace, Beach

Spacious 1-BR, 2-King Beds, Near Mayo, Pool, Gym, Fast Wifi Workspace, Beach
Deerwood
10.0 out of 10, Exceptional, (1 review)
"Accommodation was fantastic. Loved the location. Very clean and roomy. Getting in was a nightmare, instructions were not very clear and took an hour to finally find the parking lot and entrance. This is a very large complex with many buildings. Pool was great. The host was tardy in getting back to us. Great stay would recommend "
United States
Christine W.
$261 nightly
The price is $294
Sep 28 - Sep 29
Total with taxes and fees
Spacious 1-BR, 2-King Beds, Near Mayo, Pool, Gym, Fast Wifi Workspace, Beach
A gym with ceiling fans, weightlifting equipment, treadmills, and exercise bikes.

4. Cozy 2BR • Mayo Clinic & Beach • Hot Tub +King Bed

Cozy 2BR • Mayo Clinic & Beach • Hot Tub +King Bed
Jacksonville
10.0 out of 10, Exceptional, (2 reviews)
"Absolutely wonderful! Hoping to come back"
United States
Malina K.
$260 nightly
The price is $293
Sep 28 - Sep 29
Total with taxes and fees
Cozy 2BR • Mayo Clinic & Beach • Hot Tub +King Bed

5. San Marco/Downtown Modern Suite

San Marco/Downtown Modern Suite
San Marco
9.8 out of 10, Exceptional, (22 reviews)
"Yes our host was most accommodating and the suite was very clean "
United States
John C.
$169 nightly
The price is $189
Sep 28 - Sep 29
Total with taxes and fees
San Marco/Downtown Modern Suite
A hotel with a modern design, featuring a flat roof, satellite dishes, and a well-maintained garden with palm trees.

6. 2 Full Beds | Non-Smoking, Kitchen

2 Full Beds | Non-Smoking, Kitchen
Southside
10.0 out of 10, Exceptional, (6 reviews)
$59 nightly
The price is $70
Sep 28 - Sep 29
Total with taxes and fees
2 Full Beds | Non-Smoking, Kitchen
A compact hotel room with a bed, a desk, and a kitchenette.

7. Cozy Queen Bed ADA Room|Free Wifi

Cozy Queen Bed ADA Room|Free Wifi
Jacksonville
10.0 out of 10, Exceptional, (2 reviews)
"Would book again confidently. It's simple but cozy with thoughtful details like a tub and microwave available to guests."
United States
Anonymous traveler
$60 nightly
The price is $71
Sep 28 - Sep 29
Total with taxes and fees
Cozy Queen Bed ADA Room|Free Wifi
A living room with two black leather sofas, a glass coffee table, and a beige armchair. There is a red and beige rug on the floor.

8. AWESOME/LUXURY/PERFECT LOCATION/PVT HOME @SE/Mandarin

AWESOME/LUXURY/PERFECT LOCATION/PVT HOME @SE/Mandarin
Del Rio
10.0 out of 10, Exceptional, (55 reviews)
"Great property. Close to lots of things Clean, and very spacious."
United States
Jon C.
$264 nightly
The price is $296
Sep 28 - Sep 29
Total with taxes and fees
AWESOME/LUXURY/PERFECT LOCATION/PVT HOME @SE/Mandarin
A modern kitchen with wooden flooring, a built-in oven, and a refrigerator.

9. 2-bedroom townhome in Bartram Park, full remote work set up.

2-bedroom townhome in Bartram Park, full remote work set up.
Jacksonville
8.4 out of 10, Very good, (6 reviews)
"Was a convenient stop for our stay in town."
United States
Jeni M.
$229 nightly
The price is $257
Oct 4 - Oct 5
Total with taxes and fees
2-bedroom townhome in Bartram Park, full remote work set up.

10. Serene Bliss: Stylish 1BR Unit in Resort Complete

Serene Bliss: Stylish 1BR Unit in Resort Complete
Jacksonville, Florida 32224
10.0 out of 10, Exceptional, (3 reviews)
"We came late (2am) and the host was quick to respond with check-in questions. Apartment was very clean and the community was quiet."
United States
Ana M.
$249 nightly
The price is $280
Oct 3 - Oct 4
Total with taxes and fees
Serene Bliss: Stylish 1BR Unit in Resort Complete
A dining area with a round table, four chairs, and a television mounted on the wall.

11. Modern Retreat 6 Min to Mayo Clinic & 10 min to Jax Beach. Cozy Suite-apartment

Modern Retreat 6 Min to Mayo Clinic & 10 min to Jax Beach. Cozy Suite-apartment
Jacksonville
10.0 out of 10, Exceptional, (1 review)
"I cannot say enough good things about host or the property. They were so helpful getting settled in, and the property was actually nicer than the photos! Everything you can think of has been provided, coffee pods/sugar/creamer. Complex itself is new and in good shape, Neighboors were quiet and the property grounds were immaculate. We come often for trips to the Mayo Clinic and 100% would stay again. We have stayed at multiple properties in Jax over the last 6 months, this is by far the...
United States
Gulf Lifts of Florida of Florida & Alabama LLC
$258 nightly
The price is $290
Sep 30 - Oct 1
Total with taxes and fees
Modern Retreat 6 Min to Mayo Clinic & 10 min to Jax Beach. Cozy Suite-apartment

12. Serene Mins 2 Beach Sand Brookdale Mayo Clinic Everbank

Serene Mins 2 Beach Sand Brookdale Mayo Clinic Everbank
Southside
$216 nightly
The price is $243
Sep 28 - Sep 29
Total with taxes and fees
Serene Mins 2 Beach Sand Brookdale Mayo Clinic Everbank
An outdoor lounge area with a fire pit, lounge chairs, and umbrellas.

13. Top Tier King Bed Stunning View Near Mayo Beach

Top Tier King Bed Stunning View Near Mayo Beach
Southside
9.2 out of 10, Wonderful, (5 reviews)
"I enjoyed my stay at this unit. The building was quiet and the host was very attentive. The amenities were great! I would most certainly stay again."
United States
Andrea D.
$303 nightly
The price is $341
Sep 29 - Sep 30
Total with taxes and fees
Top Tier King Bed Stunning View Near Mayo Beach

14. Tropical Oasis - 10 min from shopping, restaurants & downtown, 20 min Naval base

Tropical Oasis - 10 min from shopping, restaurants & downtown, 20 min Naval base
Southside
10.0 out of 10, Exceptional, (3 reviews)
"great stay thank you"
United States
Holly P.
$372 nightly
The price is $372
Oct 2 - Oct 3
Total with taxes and fees
Tropical Oasis - 10 min from shopping, restaurants & downtown, 20 min Naval base
A modern living room with a sofa, coffee table, fireplace, and a large TV screen displaying a beach scene.

15. Mandarin Retreat - Entire Home

Mandarin Retreat - Entire Home
jacksonville
10.0 out of 10, Exceptional, (4 reviews)
"All around awesome place . Stayed for 4 nights. 10/10"
United States
Drew B.
$307 nightly
The price is $324
Sep 28 - Sep 29
Total with taxes and fees
Mandarin Retreat - Entire Home
A spacious living area with a foosball table, a kitchen, and large windows.

16. Beachline Oasis Luxury Retreat Near Beaches

Beachline Oasis Luxury Retreat Near Beaches
Golden Glades - The Woods
10.0 out of 10, Exceptional, (1 review)
$209 nightly
The price is $234
Sep 30 - Oct 1
Total with taxes and fees
Beachline Oasis Luxury Retreat Near Beaches
A modern kitchen with grey cabinets, a stainless steel refrigerator, a microwave, and a coffee maker.

17. La Casita by Amarelys and lazaro

La Casita by Amarelys and lazaro
Southside
10.0 out of 10, Exceptional, (9 reviews)
"Was very clean and comfortable "
United States
Natasha M.
$249 nightly
The price is $280
Sep 30 - Oct 1
Total with taxes and fees
La Casita by Amarelys and lazaro
A living room with a sectional sofa, a ceiling fan, and a view through large windows.

18. 2-bedroom condo on beach Blv by Jaguar Stadium with two pools

2-bedroom condo on beach Blv by Jaguar Stadium with two pools
Jacksonville
$159 nightly
The price is $178
Sep 28 - Sep 29
Total with taxes and fees
2-bedroom condo on beach Blv by Jaguar Stadium with two pools
A corner of a room with white walls and three white shelves.

19. Sunshine Haven: 2BR w/ Pool, Hot tub, Gym

Sunshine Haven: 2BR w/ Pool, Hot tub, Gym
Jacksonville
$270 nightly
The price is $270
Sep 28 - Sep 29
Total with taxes and fees
Sunshine Haven: 2BR w/ Pool, Hot tub, Gym
A spacious living room with a white sofa, wooden flooring, and a dining area with chairs and a table.

20. Central Avenues Central Cozy 3BR@ Water

Central Avenues Central Cozy 3BR@ Water
Jacksonville
9.4 out of 10, Exceptional, (3 reviews)
"Great space, we only stayed 1 night but it was comfy! Hosts communicate great! "
United States
Carolyne H.
$343 nightly
The price is $386
Sep 29 - Sep 30
Total with taxes and fees
Central Avenues Central Cozy 3BR@ Water
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southeast Jacksonville Hotel Reviews

Holiday Inn Express Jacksonville South Bartram Prk by IHG

Holiday Inn Express Jacksonville South Bartram Prk by IHG

10/10 Excellent
"Comfortable beds, clean room fantastic breakfast, very helpful staff."
John 1-night trip
Posted less than an hour ago
Holiday Inn Express Jacksonville South Bartram Prk by IHG

Find out more about Southeast Jacksonville

Everything you need to know about Southeast Jacksonville vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Southeast Jacksonville vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Southeast Jacksonville vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Southeast Jacksonville vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Southeast Jacksonville. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Southeast Jacksonville in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $62 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Southeast Jacksonville rentals

At Expedia, we put the best Southeast Jacksonville vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Southeast Jacksonville rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Southeast Jacksonville vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Southeast Jacksonville. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia