Find Adults Only Resorts & Hotels in St. Louis, MO from $193

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Top Adults only hotels in St. Louis

Moonrise Hotel
4 out of 5
6177 Delmar Blvd, St. Louis, MO
$163 nightly
The price is $193 total per night from Sep 8 to Sep 9
$193 total
Sep 8 - Sep 9
Total with taxes and fees
8.8/10 Excellent! (1,847 reviews)
"Staff were very nice but there wasn’t any spare travel toiletries and no hand soap in the bathroom, even asked and they were all out. Quiet and dog friendly. Onsite parking felt safe but still brought belongings inside since it’s a public parking area. Overall good, but rooms really needed a deep ..."

Reviewed on Aug 21, 2025

Moonrise Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about St. Louis

Find out more about St. Louis

Discover top St. Louis (and vicinity) attractions

The greater St. Louis area offers a vibrant blend of cultural and recreational experiences perfect for the Quality Seeker family. Start your adventure at the iconic Gateway Arch, where you can take a tram ride to the top for breathtaking views of the Mississippi River and the city skyline. A visit to the Saint Louis Zoo in Forest Park is a must, where the world-class exhibits and engaging animal encounters provide a full day of family fun, all at no admission cost! Explore the Missouri Botanical Garden, a stunning 79-acre oasis featuring a variety of themed gardens and a beautiful conservatory, perfect for leisurely strolls and family picnics. Don’t miss out on the City Museum, an interactive playground housed in a former shoe factory, which offers climbing structures, caves, and whimsical installations that will delight both kids and adults alike. For dining and shopping, the Delmar Loop is an eclectic district filled with unique boutiques, eateries, and live music venues that cater to all tastes. When it comes to accommodations, consider staying in the Central West End, known for its upscale hotels and nearby attractions, ensuring a convenient and luxurious experience. After a day of exploration, unwind at a boutique hotel that offers personalized service and comfortable amenities, making your family's stay both relaxing and memorable.

Frequently asked questions

How much do adults-only hotels in St. Louis cost?
Costs for an adults-only hotel in St. Louis may change due to, among other things, the star rating and amenities provided by the hotel. Whatever your budget, you'll discover a grown-up getaway where you can relax in peace and quiet with Expedia.
Are there any adult-only all-inclusive resorts in St. Louis?
There are no adult-only all-inclusive hotels or resorts in St. Louis. But if you're planning a getaway with your partner and looking for a romantic stay, consider The Lodge At Grant's Trail. Wedding services and windsurfing are a couple of the amenities here. Another great option is Drury Inn & Suites St. Louis Brentwood. Here you can enjoy access to a staffed front desk and free WiFi.
What is there to do in St. Louis near my adults-only hotel?
No matter your interests, St. Louis has tons to keep you on the move. St. Louis Zoo, Fox Theater and St. Louis Aquarium at Union Station are on many visitors' trip plans. Don't forget about Anheuser-Busch Brewery, St. Louis Science Center and St. Louis Art Museum either. With Expedia's St. Louis hotel deals, you'll be able to see even more fabulous attractions like these with the cash you save.
How can I find cheap adults-only hotels in St. Louis?
Expedia can help you easily locate cheap adults-only hotels in St. Louis. Simply use the filter tool to select budget, amenities and star rating to refine your search results and book the perfect stay in just a few clicks.
From what age can you stay in an adult-only hotel in St. Louis?
It varies, but usually you must be 16, 18 or 21 years old. Rules may be different from one property to the next, so be sure to check the fine print of the adult-only hotel or resort in St. Louis that catches your eye. Whether you're organizing a vacation with your pals or a romantic escape for two, Expedia's adult-only getaways are the place to go for kid-free, hassle-free fun.
Are all adult-only resorts all-inclusive in St. Louis?
If you're yearning for a hassle-free vacation, an adult-only all-inclusive resort serves up a big slice of R&R. To see the available options in St. Louis, enter your travel details and then click on the "all-inclusive" filter. Keep on the lookout for places that are listed as "adults only." Click on the properties you want to view to find out what you'll get for the price. The rate typically covers drinks, food and the room, on-site activities and daily entertainment.
Why book your adults-only hotel in St. Louis with Expedia?
Offering affordable rates and an excellent range of properties, Expedia makes it simple to find an adults-only hotel in St. Louis. Splurge on a high-end resort or use our handy search filters to locate a wallet-friendly stay. From the moment you enter your travel dates to when you lock in a place that ticks all your boxes, Expedia has got you covered.
When is the best time to stay at an adult-only all-inclusive resort in St. Louis?
Just about any time is a good time to stay at an adult-only all-inclusive resort in St. Louis, but there are a few factors worth thinking about. Start with the time of the year you'd like to travel. Peak season is popular and exciting, but there's a higher demand for accommodations and flights. Low season tends to be quieter and easier on your credit card. Of course, the weather is a very important part in making or breaking a getaway, so do a little research before booking your adult-only hotel or resort.
Can I cancel or change my adult-only resort booking?
You sure can. Depending on the type of hotel booking you made and how close you are to your check-in date, you may not be charged a fee. Rules can vary among our adult-only resorts and hotels, so check your itinerary or head to Expedia's Trips portal for information. If you'd like to make your vacation in St. Louis as stress-free as possible, choose adult-only accommodations that allow a full refund.

Top St. Louis Hotel Reviews

Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

10/10 Excellent
"Always super friendly staff and sparkling clean!"
Paul 2-night trip
Posted 16 hours ago
Drury Inn & Suites St. Louis Union Station