Find hotels in New Melle, MO from $68

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for New Melle hotels

1. The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1,657 reviews)
"Super helpful staff. Great hot tub."
United States
Joshua
1 day ago
$93 nightly
The price is $108
Jun 22 - Jun 23
Total with taxes and fees
The Wildwood Hotel

2. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,003 reviews)
"Will take more advantage of the pool next time."
United States
Jessica
20 hours ago
$193 nightly
The price is $226
Jul 1 - Jul 2
Total with taxes and fees
Ameristar Casino Resort and Spa

3. Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
Riverport
8.4 out of 10, Very Good, (2,215 reviews)
"It was a nice looking hotel I did enjoy the food they had at one."
United States
Irma
8 days ago
$116 nightly
The price is $136
Jun 8 - Jun 9
Total with taxes and fees
Hollywood Casino & Hotel St. Louis

4. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
7.8 out of 10, Good, (1,326 reviews)
"Property well maintained internally. Overall pleased with this budget friendly stay."
United States
Jennifer
7 days ago
$99 nightly
The price is $115
Jun 7 - Jun 8
Total with taxes and fees
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

5. Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur
3.0 star property
Creve Coeur
8.6 out of 10, Excellent, (1,000 reviews)
"We have stayed here twice and have been happy with the rooms and service."
United States
Kevin
8 days ago
$122 nightly
The price is $142
Jun 14 - Jun 15
Total with taxes and fees
Courtyard by Marriott St Louis Creve Coeur

6. Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
Chesterfield
9.6 out of 10, Exceptional, (1,170 reviews)
"Good Breakfast pancakes pre made. 3 drink kickback happy hour."
United States
Raymond
4 days ago
$136 nightly
The price is $158
Jun 7 - Jun 8
Total with taxes and fees
Drury Plaza Hotel St. Louis Chesterfield

7. Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,014 reviews)
"The bed is very comfortable. We get a good nights sleep."
United States
Pennie
5 days ago
$89 nightly
The price is $105
Jun 9 - Jun 10
Total with taxes and fees
Sleep Inn & Suites O'Fallon MO - Technology Drive

8. Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1,036 reviews)
"The room was very clean. Love the high ceilings. We had a wonderful stay."
United States
Michael T
5 days ago
$139 nightly
The price is $159
Jun 14 - Jun 15
Total with taxes and fees
Country Inn & Suites by Radisson, St. Charles Historic District

9. Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
Valley Park
9.6 out of 10, Exceptional, (1,002 reviews)
"The stay was good overall. The experience was satisfactory overall."
United States
Hassan
3 days ago
$129 nightly
The price is $151
Jul 2 - Jul 3
Total with taxes and fees
Drury Inn & Suites Southwest St. Louis

10. Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
Riverport
7.6 out of 10, Good, (1,010 reviews)
"Very nice and quite get away, i liked it alot."
United States
Bianca
18 days ago
$93 nightly
The price is $107
Jun 15 - Jun 16
Total with taxes and fees
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

11. Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
O'Fallon
8.6 out of 10, Excellent, (930 reviews)
"We stay at this location frequently; always a great experience."
United States
Sheryl
13 days ago
$118 nightly
The price is $139
Jun 7 - Jun 8
Total with taxes and fees
Holiday Inn Express St. Louis West - O'Fallon by IHG

12. Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG
3.0 star property
O'Fallon
8.6 out of 10, Excellent, (438 reviews)
"Excellent breakfast staff. Did a wonderful job."
United States
Kelly
May 2nd, 2026
$134 nightly
The price is $158
Jun 14 - Jun 15
Total with taxes and fees
Staybridge Suites O'Fallon Chesterfield by IHG

13. Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1,007 reviews)
"From the great customer service to the clean room. This was a great stay."
United States
Karla
1 day ago
$145 nightly
The price is $168
Jun 7 - Jun 8
Total with taxes and fees
Drury Plaza Hotel St. Louis St. Charles

14. Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1,000 reviews)
"Very nice hotel I always enjoy myself when I stay."
United States
Nialia
22 days ago
$160 nightly
The price is $184
Jun 7 - Jun 8
Total with taxes and fees
Embassy Suites by Hilton St. Louis St. Charles

15. Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur
3.0 star property
Creve Coeur
9.2 out of 10, Wonderful, (1,005 reviews)
"Over all I in joyed my stay."
United States
samira
7 days ago
$140 nightly
The price is $163
Jul 3 - Jul 4
Total with taxes and fees
Drury Plaza Hotel St. Louis Creve Coeur

16. Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very Good, (1,002 reviews)
"Breakfast was good, staff friendly."
United States
Stephanie
11 days ago
$104 nightly
The price is $119
Jun 7 - Jun 8
Total with taxes and fees
Comfort Suites St Charles - St Louis

17. Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1,007 reviews)
"Very nice staff! And the breakfast was great!!"
United States
Mohsen
3 days ago
$110 nightly
The price is $126
Jun 14 - Jun 15
Total with taxes and fees
Drury Inn & Suites St. Louis St. Peters

18. Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (919 reviews)
"The rooms are very comfortable always quiet. I've always found the property to be clean."
United States
Rickilee
1 day ago
$139 nightly
The price is $165
Jun 7 - Jun 8
Total with taxes and fees
Holiday Inn Express & Suites Wentzville St Louis West by IHG

19. Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO
3.0 star property
O'Fallon
8.8 out of 10, Excellent, (740 reviews)
"Very nice, very clean, comfortable hotel, we'll definitely be back. We found a new favorite."
United States
Michael
18 days ago
$144 nightly
The price is $170
Jun 14 - Jun 15
Total with taxes and fees
Hilton Garden Inn St. Louis/O'Fallon MO

20. Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,237 reviews)
"Clean room, good staff, breakfast OK."
United States
MARK
1 day ago
$88 nightly
The price is $101
Jun 14 - Jun 15
Total with taxes and fees
Wingate by Wyndham St. Louis/Fenton Route 66
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top New Melle Hotel Reviews

More cheap stays in New Melle

Hotels in New Melle with star-rating

Why book with Expedia?

  • Flexible booking

    On Expedia, you can find plenty of hotels with flexible cancellation in New Melle using the “Fully refundable property” search filter. Just be sure to always double-check each hotel's cancellation policy before booking.

  • Book now and pay later

    With countless book now, pay later options, there's no need to wait till payday to grab a deal. Use the “Reserve now, pay later” search filter to view all properties available with this payment option in New Melle.

  • Hotel comparison

    Thanks to the handy “Compare properties” tool on Expedia, you can compare hotels in New Melle side by side with just a few clicks.

  • Member prices

    Join Expedia's loyalty program, One Key, for free and unlock Member Prices and rewards on select hotels worldwide. Simply log in when you search and look out for the blue savings label.

Frequently asked questions

What is the best area to stay in New Melle?
The best area to stay in New Melle is in the heart of the town itself, particularly around the intersection of Highway D and Foristell Road. This central location offers convenient access to the town's main establishments.

Couples looking for a peaceful getaway will appreciate this area. New Melle is known for its rural setting and quiet atmosphere, providing a relaxing escape from city life. You'll find local eateries and shops within a short drive, making it easy to enjoy the town's offerings without extensive travel.

For those interested in exploring the scenic countryside and local attractions, staying centrally in New Melle is ideal.
When is the best time to go to New Melle?
The best time to visit New Melle is during the spring (April to June) and fall (September to October) months.

These seasons offer the most pleasant weather conditions, with comfortable temperatures and less humidity, making it ideal for exploring the outdoors and enjoying local events. Spring brings blooming wildflowers and lush greenery, while fall showcases beautiful foliage, creating a scenic backdrop for your visit.

For visitors interested in outdoor activities like hiking, cycling, or exploring the local wineries, these shoulder seasons provide the great climate. The mild temperatures allow for extended periods outdoors without the discomfort of summer heat or winter cold, making it a great time for couples or solo travelers to enjoy the natural beauty of the area.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in New Melle.
How can I save on a New Melle hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible New Melle hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a New Melle hotel?
Prices for hotels in New Melle often vary, but you can find a great deal from $68 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia