Title: Top 10 Hotels in Whetsell, SC from $63 - Competitive Prices | Expedia.com [Vacation Rentals in Whetsell](https://expedia.com/Whetsell-Vacation-Rentals.d553248635974902828.Travel-Guide-VacationRentals)[Car Rentals in Whetsell](https://expedia.com/Car-Rentals-In-Whetsell.d553248635974902828.Car-Rental-Guide)[Whetsell Vacation Packages](https://expedia.com/Whetsell.d553248635974902828.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Whetsell Pool [](https://www.expedia.com/Hotel-Search?destination=Whetsell%2C+South+Carolina%2C+United+States+of+America®ionId=553248635974902828&latLong=33.333771%2C-80.590096&adults=2&startDate=2026-03-24&d1=2026-03-24&endDate=2026-03-26&d2=2026-03-26&amenities=POOL) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Whetsell%2C+South+Carolina%2C+United+States+of+America®ionId=553248635974902828&latLong=33.333771%2C-80.590096&adults=2&startDate=2026-03-24&d1=2026-03-24&endDate=2026-03-26&d2=2026-03-26&amenities=PETS) Family friendly [](https://www.expedia.com/Hotel-Search?destination=Whetsell%2C+South+Carolina%2C+United+States+of+America®ionId=553248635974902828&latLong=33.333771%2C-80.590096&adults=2&startDate=2026-03-24&d1=2026-03-24&endDate=2026-03-26&d2=2026-03-26&travelerType=family_friendly) Condo [](https://www.expedia.com/Hotel-Search?destination=Whetsell%2C+South+Carolina%2C+United+States+of+America®ionId=553248635974902828&latLong=33.333771%2C-80.590096&adults=2&startDate=2026-03-24&d1=2026-03-24&endDate=2026-03-26&d2=2026-03-26&lodging=CONDO) ## Check prices for these dates Tonight [Mar 10 - Mar 11](https://www.expedia.com/Hotel-Search?regionId=553248635974902828&startDate=2026-03-10&endDate=2026-03-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 11 - Mar 12](https://www.expedia.com/Hotel-Search?regionId=553248635974902828&startDate=2026-03-11&endDate=2026-03-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248635974902828&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=553248635974902828&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Whetsell hotels ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/6c8567ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/51caeaed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/1f93ecf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/0af71c77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Santee [](https://www.expedia.com/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) Santee 6.4/10 (311 reviews) "Last minute arrangements stay was quiet and peaceful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Iasia $68 nightly $76 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/8136c59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/070e1043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/4686cd8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/9e846421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Santee [](https://www.expedia.com/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) Santee 6.6/10 (646 reviews) "A good option if traveling with pets. The hotel is clean and well maintained but dated. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen $58 nightly $65 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/d34bd120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/2def81ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/daa776a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/41ed20e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Santee I-95 [](https://www.expedia.com/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) Santee 6.4/10 (552 reviews) "Room was clean. Staff was friendly. Bartender was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dean $86 nightly $96 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/aa634b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/dc3438b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/77599f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santee [](https://www.expedia.com/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) Santee 6.8/10 (445 reviews) "The staff was very friendly and helpful. Room was clean and beds were so comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy $70 nightly $78 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/5b7ee831.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/ebe97e99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee [](https://www.expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) Santee 7.2/10 Good (704 reviews) "Nice quiet room and a delicious breakfast at a reasonable rate." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph B $63 nightly $70 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/1295e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/50891687.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/4c792a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee I-95 [](https://www.expedia.com/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) Santee 6.0/10 (480 reviews) "Clean room but needs an exhaust fan in the bathroom " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leesa $59 nightly $66 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/5f0b6fe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/5ef3d5ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG [](https://www.expedia.com/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) Santee 8.2/10 Very Good (1,002 reviews) "Everything was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie $127 nightly $141 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Jetted Tub | Desk, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ec6d0d77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/044c704d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/67da47be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn [](https://www.expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) Santee 8.8/10 Excellent (1,008 reviews) "Courteous reception,clean rooms and great breakfast! Have been there many times in the last 15 years and I will return.!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Roger $112 nightly $124 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall) | Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee [](https://www.expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) Santee 8.0/10 Very Good (1,009 reviews) "Clean rooms, nice staff, decent breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale $104 nightly $115 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/fcd98400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5472b058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 [](https://www.expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) Santee 9.6/10 Exceptional (1,008 reviews) "Liked the size of the room, the staff and the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Virginia $124 nightly $138 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Panoramic Tent | Lake view](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/caef79e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View | Terrace/patio](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/w4138h5635x0y0-48933ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View | Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/b0419165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Tent | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/9123f55d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bells Marina & Resort [](https://www.expedia.com/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) Eutawville 8.6/10 Excellent (90 reviews) "Super quaint, quiet, nice little get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen $108 nightly $120 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/c62bc9b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/90e33e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/4d4cc6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/43fe19ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Saint George, SC – I-95 [](https://www.expedia.com/St-George-Hotels-Knights-Inn-Saint-George.h6132858.Hotel-Information) St. George 6.6/10 (194 reviews) "The room is clean and a nice size ,water was hot for a nice relaxing shower.The bed is very comfortable Just wish had a coffee maker in room .very friendly check in .would definitely recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janice $64 nightly $71 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/St-George-Hotels-Knights-Inn-Saint-George.h6132858.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/320acff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very Good (1,448 reviews) "Room were very clean and staff was very helpful. I would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charolette $80 nightly $89 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/d654e116.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee [](https://www.expedia.com/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) Santee 9.8/10 Exceptional (1,012 reviews) "Room had everything we wanted... very clean & fresh, microwave, fridge, comfy beds. Hotel was very nice and close to everything needed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcia $125 nightly $139 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/99021580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/40f69ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee [](https://www.expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) Santee 9.2/10 Wonderful (755 reviews) "Large, clean room, friendly staff, nice breakfast. Would stay again. Also a nice Mexican restaurant nearby for dinner. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan $113 nightly $125 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/e17744ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/a22ac41a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/38babe0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/515ae417.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Budget Inn By Belvilla St George I-95 [](https://www.expedia.com/Reevesville-Hotels-Budget-Inn-St-George-I-95.h109318932.Hotel-Information) St. George 7.6/10 Good (187 reviews) "This is a great value for a budget hotel. It's an older complex but clean and well maintained. It's close to decent food options for tired travelers and the front desk staff was pleasant and helpful. If you are looking for a convient, well priced stopover, I recommend this location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim $66 nightly $73 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Reevesville-Hotels-Budget-Inn-St-George-I-95.h109318932.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/c1880a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/3a41c72c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/bc8b5a93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/efa2345e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peach Tree Inn [](https://www.expedia.com/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) St. George 7.4/10 Good (172 reviews) "The room was very clean , the price was very reasonable and the staff was very helpful. I'll definitely stay again. And recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Precious $68 nightly $73 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) ![Room, 1 King Bed, Non Smoking | Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e088653f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e85d0e8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/59cd1b4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/2eadf4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham St George [](https://www.expedia.com/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) St. George 7.6/10 Good (1,004 reviews) "Clean, relaxing, friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Smith $100 nightly $111 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/890000/889300/889204/666bcafd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/890000/889300/889204/308a47cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/890000/889300/889204/f02ed3ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/890000/889300/889204/e2987c1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge St. George [](https://www.expedia.com/St-George-Hotels-Econo-Lodge-St-George.h889204.Hotel-Information) St. George 6.4/10 (268 reviews) "It was nice all together " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcia $59 nightly $63 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/St-George-Hotels-Econo-Lodge-St-George.h889204.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/962a9377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/d3f2bbda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Non Smoking | Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/11ccce69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/27b2c420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn St George, SC [](https://www.expedia.com/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) St. George 7.4/10 Good (659 reviews) "Breakfast was an overstatement!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicki $75 nightly $84 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-24&endDate=2026-03-25®ionId=553248635974902828&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_553248635974902828) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FWhetsell-Hotels.d553248635974902828.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FWhetsell-Hotels.d553248635974902828.Travel-Guide-Hotels) ## Top Whetsell Hotel Reviews ![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26_y.jpg) ### Fairfield Inn by Marriott Orangeburg 10/10 Excellent "Great price and real good breakfast" [](https://expedia.com/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627_y.jpg) ### Tru By Hilton Santee 8/10 Good "The hotel room was clean, had a lot of towels. Was able to walk around the building for exercise. Cracker Barrel next door. Bed and pillows were uncomfortable. The water pressure in the shower was awful. Had hot water but the pressure was very low. They have a sign for quiet time in the hotel but we had someone upstairs making noise from 9 pm to almost 11 and the person next to us as well. The hotel itself is nice. The breakfast needs a bigger variety of food. Had bagels and bread. Could have english muffins or danish besides those. People at the front desk were nice. Would use this hotel again but they have to crack down on the noise in the building. Lack of rugs in the rooms does not help. Please have a better selection of foods at breakfast." [](https://expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Budget Inn By Belvilla St George I-95](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/e17744ea_y.jpg) ### Budget Inn By Belvilla St George I-95 10/10 Excellent "Good" [](https://expedia.com/Reevesville-Hotels-Budget-Inn-St-George-I-95.h109318932.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "Parking was safe. The staff was excellent. The breakfast was delicious. The bed was incredible. The room was clean. Had a great experience." [](https://expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Days Inn by Wyndham St George](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e088653f_y.jpg) ### Days Inn by Wyndham St George 6/10 Okay "Few choices of convience" [](https://expedia.com/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4_y.jpg) ### Baymont by Wyndham Santee 4/10 Poor "The room could have been cleaner around the sink. There was a used towel hanging on the bathroom door, and the body wash was empty. Okay besides that. " [](https://expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Quality Inn & Suites Santee I-95](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695_y.jpg) ### Quality Inn & Suites Santee I-95 6/10 Okay "Rooms are updated and clean. Very good value for the price of the room. " [](https://expedia.com/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516_y.jpg) ### Comfort Inn & Suites Santee 8/10 Good "The stay was good though not as good as other Comfort Inn and Suites. Room was very clean but toilet seat looked like it had come " [](https://expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Holiday Inn Santee by IHG](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3_y.jpg) ### Holiday Inn Santee by IHG 8/10 Good "Parking was easy. There are not many if any restaurants nearby. Some fast food places but I didn't explore much. My room was quiet and clean. Easy check-in and checkout. The lady at the desk was friendly. " [](https://expedia.com/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ## More cheap stays in Whetsell ![Peach Tree Inn](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/c1880a3d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Peach Tree Inn 111 Conners Dr St. George SC $68 nightly $73 total Mar 11 - Mar 12 Total with taxes and fees 7.4/10 Good! (172 reviews) [](https://expedia.com/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Santee 249 Britain Street Santee SC $80 nightly $89 total Mar 11 - Mar 12 Total with taxes and fees 8/10 Very Good! (1,448 reviews) [](https://expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Days Inn by Wyndham St George](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e088653f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham St George 139 Motel Dr St. George SC $100 nightly $111 total Mar 11 - Mar 12 Total with taxes and fees 7.6/10 Good! (1,004 reviews) [](https://expedia.com/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn & Suites Santee 221 Britain St Santee SC $104 nightly $115 total Mar 17 - Mar 18 Total with taxes and fees 8/10 Very Good! (1,009 reviews) [](https://expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Santee Inn I 95 Exit 98 Santee SC $112 nightly $124 total Mar 11 - Mar 12 Total with taxes and fees 8.8/10 Excellent! (1,008 reviews) [](https://expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St. Santee SC $113 nightly $125 total Mar 16 - Mar 17 Total with taxes and fees 9.2/10 Wonderful! (755 reviews) [](https://expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ## Hotels in Whetsell with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 1 properties [](https://expedia.com/4Star-Whetsell-Hotels.s40-0-d553248635974902828.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 6 properties [](https://expedia.com/3Star-Whetsell-Hotels.s30-0-d553248635974902828.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 41 properties [](https://expedia.com/2Star-Whetsell-Hotels.s20-0-d553248635974902828.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Whetsell? > This area is the heart of Whetsell, offering a blend of historic architecture and modern amenities. Main Street is lined with local shops, art galleries, and diverse dining options, leading down to the scenic Riverwalk along the Whetsell River. It's a very walkable district, making it convenient for exploring on foot. > > > Couples will find the Historic Downtown ideal for a refined and relaxing getaway. The area offers boutique hotels, intimate restaurants, and easy access to cultural attractions like the Whetsell Art Museum and evening strolls along the Riverwalk, which features beautifully maintained gardens and public art installations. > > > For solo travelers looking for convenience and a central base, the Historic Downtown also provides excellent options. ### When is the best time to go to Whetsell? > During spring, temperatures are mild, typically ranging from the low 60s to mid-70s Fahrenheit. This period is ideal for enjoying the blooming gardens and taking part in local festivals without the intense heat and humidity of summer. Travelers who enjoy comfortable weather for walking and sightseeing will find this time particularly appealing. > > > Fall also offers comfortable temperatures, generally from the low 60s to high 70s Fahrenheit, along with lower humidity. The changing foliage provides a scenic backdrop for exploring the area's natural beauty, such as the trails around Lake Whetsell. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Whetsell hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Whetsell hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Providence Hotels ](https://www.expedia.com/Providence-Hotels.d553248635975849205.Travel-Guide-Hotels) - [Bowman Hotels ](https://www.expedia.com/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [4 Star Hotels in Bowman ](https://www.expedia.com/4Star-Bowman-Hotels.s40-0-d553248634998681915.Travel-Guide-Filter-Hotels) - [Reevesville Hotels ](https://www.expedia.com/Reevesville-Hotels.d553248634998787689.Travel-Guide-Hotels) - [St. George Hotels ](https://www.expedia.com/St-George-Hotels.d183948.Travel-Guide-Hotels) - [Holly Hill Hotels ](https://www.expedia.com/Holly-Hill-Hotels.d3000455972.Travel-Guide-Hotels) - [Pet-Friendly Hotels in St. George ](https://www.expedia.com/St-George-Hotels-Pet-Friendly-Hotel.0-0-d183948-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - 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