Title: Top 10 Hotels in Whetsell, SC from $63 - Competitive Prices | Expedia.com [Vacation Rentals in Whetsell](https://expedia.com/Whetsell-Vacation-Rentals.d553248635974902828.Travel-Guide-VacationRentals)[Car Rentals in Whetsell](https://expedia.com/Car-Rentals-In-Whetsell.d553248635974902828.Car-Rental-Guide)[Whetsell Vacation Packages](https://expedia.com/Whetsell.d553248635974902828.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Whetsell Family friendly [](https://www.expedia.com/Hotel-Search?destination=Whetsell%2C+South+Carolina%2C+United+States+of+America®ionId=553248635974902828&latLong=33.333771%2C-80.590096&adults=2&startDate=2026-03-30&d1=2026-03-30&endDate=2026-04-01&d2=2026-04-01&travelerType=family_friendly) Pool [](https://www.expedia.com/Hotel-Search?destination=Whetsell%2C+South+Carolina%2C+United+States+of+America®ionId=553248635974902828&latLong=33.333771%2C-80.590096&adults=2&startDate=2026-03-30&d1=2026-03-30&endDate=2026-04-01&d2=2026-04-01&amenities=POOL) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Whetsell%2C+South+Carolina%2C+United+States+of+America®ionId=553248635974902828&latLong=33.333771%2C-80.590096&adults=2&startDate=2026-03-30&d1=2026-03-30&endDate=2026-04-01&d2=2026-04-01&amenities=PETS) Cottage [](https://www.expedia.com/Hotel-Search?destination=Whetsell%2C+South+Carolina%2C+United+States+of+America®ionId=553248635974902828&latLong=33.333771%2C-80.590096&adults=2&startDate=2026-03-30&d1=2026-03-30&endDate=2026-04-01&d2=2026-04-01&lodging=COTTAGE) ## Check prices for these dates Tonight [Mar 16 - Mar 17](https://www.expedia.com/Hotel-Search?regionId=553248635974902828&startDate=2026-03-16&endDate=2026-03-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 17 - Mar 18](https://www.expedia.com/Hotel-Search?regionId=553248635974902828&startDate=2026-03-17&endDate=2026-03-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=553248635974902828&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=553248635974902828&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Whetsell hotels ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/6c8567ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/7dca4a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/1f93ecf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/0af71c77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Santee [](https://www.expedia.com/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) Santee 6.4/10 (311 reviews) "Last minute arrangements stay was quiet and peaceful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Iasia $68 nightly $76 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/8136c59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/9e846421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/070e1043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/5b49de0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Santee [](https://www.expedia.com/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) Santee 6.6/10 (646 reviews) "A good option if traveling with pets. The hotel is clean and well maintained but dated. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen $58 nightly $65 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/aa634b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2262fc91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/77599f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santee [](https://www.expedia.com/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) Santee 6.8/10 (446 reviews) "The beds are super comfy. I liked how quiet it was in the room and the staff was very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy $75 nightly $83 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/5b7ee831.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee [](https://www.expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) Santee 7.2/10 Good (706 reviews) "Good location for amenities and walking and driving distance " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gezeall $63 nightly $70 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/1295e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/50891687.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/4c792a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee I-95 [](https://www.expedia.com/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) Santee 6.0/10 (484 reviews) "Rooms are updated and clean. Very good value for the price of the room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark $59 nightly $66 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/5f0b6fe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/5ef3d5ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG [](https://www.expedia.com/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) Santee 8.2/10 Very Good (1,001 reviews) "Staff was amazing — but they were very short staffed so the one person at the bar/restaurant (Dee) and the one person at the desk did the job of 3 people each!! Place is being renovated so not quite there yet but clean and good stay. And again incredible staff!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah $131 nightly $145 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall) | Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/0b55a618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee [](https://www.expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) Santee 8.0/10 Very Good (1,003 reviews) "Hotel was a little dated but clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah $106 nightly $118 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/67da47be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Jetted Tub | Desk, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ec6d0d77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn [](https://www.expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) Santee 8.8/10 Excellent (1,006 reviews) "Clean room, polite staff , " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) samantha $112 nightly $124 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | Iron/ironing board, free cribs/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/1ffbf2b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/fcd98400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 [](https://www.expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) Santee 9.6/10 Exceptional (1,007 reviews) "Clean, great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph $134 nightly $149 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Panoramic Tent | Lake view](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/caef79e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View | Terrace/patio](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/w4138h5635x0y0-48933ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/ee0f57db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Tent | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/9123f55d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bells Marina & Resort [](https://www.expedia.com/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) Eutawville 8.6/10 Excellent (90 reviews) "Super quaint, quiet, nice little get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen $108 nightly $120 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/c62bc9b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/43fe19ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/4d4cc6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/815a509d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Saint George, SC – I-95 [](https://www.expedia.com/St-George-Hotels-Knights-Inn-Saint-George.h6132858.Hotel-Information) St. George 6.6/10 (194 reviews) "The room is clean and a nice size ,water was hot for a nice relaxing shower.The bed is very comfortable Just wish had a coffee maker in room .very friendly check in .would definitely recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janice $64 nightly $71 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/St-George-Hotels-Knights-Inn-Saint-George.h6132858.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/320acff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very Good (1,429 reviews) "Room were very clean and staff was very helpful. I would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charolette $80 nightly $89 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/d654e116.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee [](https://www.expedia.com/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) Santee 9.8/10 Exceptional (1,006 reviews) "Clean comfortable stay. Breakfast was a nice plus." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David $125 nightly $139 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/99021580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/40f69ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee [](https://www.expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) Santee 9.2/10 Wonderful (759 reviews) "Great place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah $115 nightly $128 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/c1880a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/bc8b5a93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/efa2345e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/3a41c72c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peach Tree Inn [](https://www.expedia.com/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) St. George 7.4/10 Good (175 reviews) "Clean carpetted floor.." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Conrad $68 nightly $73 total Mar 19 - Mar 20 Total with taxes and fees [](https://www.expedia.com/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/e17744ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/38babe0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/515ae417.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/ad05322a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Budget Inn By Belvilla St George I-95 [](https://www.expedia.com/Reevesville-Hotels-Budget-Inn-St-George-I-95.h109318932.Hotel-Information) St. George 7.6/10 Good (188 reviews) "Good" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) David $65 nightly $71 total Mar 20 - Mar 21 Total with taxes and fees [](https://www.expedia.com/Reevesville-Hotels-Budget-Inn-St-George-I-95.h109318932.Hotel-Information) ![Room, 1 King Bed, Non Smoking | Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e088653f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e85d0e8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/2eadf4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/a66aad1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham St George [](https://www.expedia.com/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) St. George 7.6/10 Good (1,003 reviews) "Traveling to Florida, hotel is located off interstate and is clean and a good location with restaurants and convenience stores for travel. Easy off the interstate and easy back on." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laurie $76 nightly $84 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/890000/889300/889204/666bcafd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/890000/889300/889204/e2987c1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/890000/889300/889204/f02ed3ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/890000/889300/889204/308a47cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge St. George [](https://www.expedia.com/St-George-Hotels-Econo-Lodge-St-George.h889204.Hotel-Information) St. George 6.4/10 (268 reviews) "Comfortable bed…nice having Direct TV…walking distance to several places to eat…great price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert $59 nightly $63 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/St-George-Hotels-Econo-Lodge-St-George.h889204.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/962a9377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/27b2c420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/11093b09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/d3f2bbda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn St George, SC [](https://www.expedia.com/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) St. George 7.4/10 Good (661 reviews) "Pleasant staff, room was clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debi $75 nightly $84 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/a9d1fec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/71b46ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/f12ce994.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Orangeburg [](https://www.expedia.com/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) Orangeburg 8.4/10 Very Good (738 reviews) "Bed was wonderhul...very satisfied " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) catherine $88 nightly $98 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-30&endDate=2026-03-31®ionId=553248635974902828&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FWhetsell-Hotels.d553248635974902828.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FWhetsell-Hotels.d553248635974902828.Travel-Guide-Hotels) ## Top Whetsell Hotel Reviews ![Budget Inn By Belvilla St George I-95](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/e17744ea_y.jpg) ### Budget Inn By Belvilla St George I-95 8/10 Good "Quick stop for the night while traveling. Decent room for the $$ " [](https://expedia.com/Reevesville-Hotels-Budget-Inn-St-George-I-95.h109318932.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4_y.jpg) ### Baymont by Wyndham Santee 8/10 Good "very pet friendly room on first floor. with parking right out front! " [](https://expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26_y.jpg) ### Fairfield Inn by Marriott Orangeburg 8/10 Good "Friendly and helpful staff!" [](https://expedia.com/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Quality Inn & Suites Santee I-95](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695_y.jpg) ### Quality Inn & Suites Santee I-95 8/10 Good "The. Property is old, the facilities are old indeed, but they work alright. I recommend. To upgrade bathroom." [](https://expedia.com/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Red Roof Inn St George, SC](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/962a9377_y.jpg) ### Red Roof Inn St George, SC 6/10 Okay "If you just want to sleep and shower this place is fine! I would not book again.. " [](https://expedia.com/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496_y.jpg) ### Hampton Inn Santee-I-95 8/10 Good "Yes " [](https://expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627_y.jpg) ### Tru By Hilton Santee 10/10 Excellent "The rooms were clean and comfortable." [](https://expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Holiday Inn Santee by IHG](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3_y.jpg) ### Holiday Inn Santee by IHG 8/10 Good "Room smells of pee an floor wasn’t cleaned " [](https://expedia.com/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Travelodge by Wyndham Santee](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40_y.jpg) ### Travelodge by Wyndham Santee 8/10 Good "The host was pleasant-and friendly Parking was convenient right outside the door It was nice having a decent restaurant within walking distance " [](https://expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ## More cheap stays in Whetsell ![Peach Tree Inn](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/c1880a3d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Peach Tree Inn 111 Conners Dr St. George SC $68 nightly $73 total Mar 19 - Mar 20 Total with taxes and fees 7.4/10 Good! (175 reviews) [](https://expedia.com/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Santee 249 Britain Street Santee SC $80 nightly $89 total Mar 17 - Mar 18 Total with taxes and fees 8/10 Very Good! (1,429 reviews) [](https://expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn & Suites Santee 221 Britain St Santee SC $106 nightly $118 total Mar 22 - Mar 23 Total with taxes and fees 8/10 Very Good! (1,003 reviews) [](https://expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Santee Inn I 95 Exit 98 Santee SC $112 nightly $124 total Mar 17 - Mar 18 Total with taxes and fees 8.8/10 Excellent! (1,006 reviews) [](https://expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St. Santee SC $115 nightly $128 total Mar 23 - Mar 24 Total with taxes and fees 9.2/10 Wonderful! (759 reviews) [](https://expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Santee-I-95 9060 Old Number Six Hwy Santee SC $134 nightly $149 total Mar 25 - Mar 26 Total with taxes and fees 9.6/10 Exceptional! (1,007 reviews) [](https://expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ## Hotels in Whetsell with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 1 properties [](https://expedia.com/4Star-Whetsell-Hotels.s40-0-d553248635974902828.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 6 properties [](https://expedia.com/3Star-Whetsell-Hotels.s30-0-d553248635974902828.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 41 properties [](https://expedia.com/2Star-Whetsell-Hotels.s20-0-d553248635974902828.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Whetsell? > This area is the heart of Whetsell, offering a blend of historic architecture and modern amenities. Main Street is lined with local shops, art galleries, and diverse dining options, leading down to the scenic Riverwalk along the Whetsell River. It's a very walkable district, making it convenient for exploring on foot. > > > Couples will find the Historic Downtown ideal for a refined and relaxing getaway. The area offers boutique hotels, intimate restaurants, and easy access to cultural attractions like the Whetsell Art Museum and evening strolls along the Riverwalk, which features beautifully maintained gardens and public art installations. > > > For solo travelers looking for convenience and a central base, the Historic Downtown also provides excellent options. ### When is the best time to go to Whetsell? > During spring, temperatures are mild, typically ranging from the low 60s to mid-70s Fahrenheit. This period is ideal for enjoying the blooming gardens and taking part in local festivals without the intense heat and humidity of summer. Travelers who enjoy comfortable weather for walking and sightseeing will find this time particularly appealing. > > > Fall also offers comfortable temperatures, generally from the low 60s to high 70s Fahrenheit, along with lower humidity. The changing foliage provides a scenic backdrop for exploring the area's natural beauty, such as the trails around Lake Whetsell. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Whetsell hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Whetsell hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Providence Hotels ](https://www.expedia.com/Providence-Hotels.d553248635975849205.Travel-Guide-Hotels) - [Bowman Hotels ](https://www.expedia.com/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [4 Star Hotels in Bowman ](https://www.expedia.com/4Star-Bowman-Hotels.s40-0-d553248634998681915.Travel-Guide-Filter-Hotels) - [Reevesville Hotels ](https://www.expedia.com/Reevesville-Hotels.d553248634998787689.Travel-Guide-Hotels) - [St. George Hotels ](https://www.expedia.com/St-George-Hotels.d183948.Travel-Guide-Hotels) - [Holly Hill Hotels ](https://www.expedia.com/Holly-Hill-Hotels.d3000455972.Travel-Guide-Hotels) - [Pet-Friendly Hotels in St. George ](https://www.expedia.com/St-George-Hotels-Pet-Friendly-Hotel.0-0-d183948-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - 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