$458 Cheap LATAM Airlines Group flights Mexico City (MEX) to Santa Cruz (VVI)

Finding cheap one-way LATAM Airlines flights from MEX to VVI from $458 on Expedia is easy — just filter by "Price (lowest to highest)." Or check out our affordable round-trip fares from $578 for your next break.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start your search for LATAM Airlines flights from MEX to VVI about one month before you want to leave. The most affordable time to reserve an international flight is usually 18 to 29 days ahead of your travel date when you can save 17% versus booking four to five months in advance. Regardless of fare class and itinerary, the best day of the week to book international airfare is usually Sunday. Friday can be the most expensive. Passengers who book on a Sunday can save 17% on average compared to those who book on a Friday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Morning" and "Early Morning" to find the earliest flights from MEX to VVI. Heading off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.