East Prairie Vacation Rentals

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Check prices for these dates

In two weeks
Jan 9 - Jan 11
In two months
Feb 20 - Feb 22
In three months
Mar 20 - Mar 22
In four months
Apr 17 - Apr 19

Our top choices for East Prairie vacation rentals

Fridge, microwave, oven, stovetop
Charming 3-bedroom house near ball park in quiet neighborhood

Vacation Home in Bardwell

Charming 3-bedroom house near ball park in quiet neighborhood
10.0 out of 10, Exceptional, (12)
"Quaint stay to see Grand and kids. "
United States
Sheila C.
$150 nightly
The price is $161
Jan 1 - Jan 2, 2026
Total with taxes and fees
Charming 3-bedroom house near ball park in quiet neighborhood
Terrace/patio
The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed

Mobile Home in Hornbeak

The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed
2.0 star property
9.8 out of 10, Exceptional, (48)
"It was peaceful and Beautiful!"
United States
Jimmie W.
$260 nightly
The price is $292
Dec 26 - Dec 27
Total with taxes and fees
The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed
Smart TV
Tranquil charming Tiny House in Clinton

Apartment in Clinton

Tranquil charming Tiny House in Clinton
2.0 star property
$136 nightly
The price is $145
Jan 4 - Jan 5, 2026
Total with taxes and fees
Tranquil charming Tiny House in Clinton
Smart TV
The Hut II on Reelfoot Lake

Mobile Home in Hornbeak

The Hut II on Reelfoot Lake
10.0 out of 10, Exceptional, (1)
"We loved that the home is walking distance to the lake! We came in to hunt for a few days, and one of the reasons we chose this home was the number of beds it offered. It was fully equipped with everything we needed to make our stay comfortable. The host was incredibly welcoming and responsive, making our stay stress-free and enjoyable. We would absolutely stay here again!"
United States
Heather T.
$260 nightly
The price is $292
Dec 28 - Dec 29
Total with taxes and fees
The Hut II on Reelfoot Lake
Fridge, microwave, oven, stovetop
Charming 3-bedroom house with WiFi, AC in amazing Hornbeak

Vacation Home in Hornbeak

Charming 3-bedroom house with WiFi, AC in amazing Hornbeak
10.0 out of 10, Exceptional, (5)
"It was enjoyable and loved the house."
United States
Paula F.
$249 nightly
The price is $278
Jan 4 - Jan 5, 2026
Total with taxes and fees
Charming 3-bedroom house with WiFi, AC in amazing Hornbeak
Outdoor dining
Come and relax at the Refuge at beautiful Reelfoot Lake!

Mobile Home in Hornbeak

Come and relax at the Refuge at beautiful Reelfoot Lake!
9.4 out of 10, Exceptional, (23)
"Great place "
United States
William
$233 nightly
The price is $261
Jan 5 - Jan 6, 2026
Total with taxes and fees
Come and relax at the Refuge at beautiful Reelfoot Lake!
Exterior detail
Tiny house on the lake With a seventy five inch t v free internet walk shower

Cabin in Tiptonville

Tiny house on the lake With a seventy five inch t v free internet walk shower
$220 nightly
The price is $249
Dec 26 - Dec 27
Total with taxes and fees
Tiny house on the lake With a seventy five inch t v free internet walk shower
Fridge, microwave, coffee/tea maker, toaster
Vacation rental attached to our house out in the country.

Apartment in Union City

Vacation rental attached to our house out in the country.
$145 nightly
The price is $162
Jan 2 - Jan 3, 2026
Total with taxes and fees
Vacation rental attached to our house out in the country.
Fridge, microwave, oven, stovetop
Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR

Mobile Home in Hornbeak

Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR
9.8 out of 10, Exceptional, (56)
"Nice place, has everything you need."
United States
Joe V.
$260 nightly
The price is $291
Jan 1 - Jan 2, 2026
Total with taxes and fees
Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR
Fridge, microwave, oven, stovetop
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Vacation Home in New Madrid

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
10.0 out of 10, Exceptional, (1)
"The host was very quick to respond and so great to work with for on our stay. "
United States
Jessica S.
$341 nightly
The price is $341
Jan 3 - Jan 4, 2026
Total with taxes and fees
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
Fridge, microwave, oven, stovetop
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

Vacation Home in Hornbeak

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
2.0 star property
10.0 out of 10, Exceptional, (1)
"The house was exaclty what we needed. It had everything we needed. We will be back. Great set up for a large group. "
United States
Jon R.
$343 nightly
The price is $384
Dec 29 - Dec 30
Total with taxes and fees
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Outdoor dining
Log Cabin.

Cabin in Hornbeak

Log Cabin.
9.0 out of 10, Wonderful, (32)
"Nice place, would book again! "
United States
Lisette B.
$424 nightly
The price is $474
Jan 7 - Jan 8, 2026
Total with taxes and fees
Log Cabin.
Exterior
Guest house and spacious shop located between Discovery Park and Reelfoot Lake

Vacation Home in Union City

Guest house and spacious shop located between Discovery Park and Reelfoot Lake
10.0 out of 10, Exceptional, (3)
"Wonderful place to relax. Home has everything you need. The additional party barn is an added bonus!!"
United States
william P.
$345 nightly
The price is $387
Dec 31 - Jan 1, 2026
Total with taxes and fees
Guest house and spacious shop located between Discovery Park and Reelfoot Lake
Private kitchen
Sunkist beach house. Lake side house 3 bedroom house

Vacation Home in Tiptonville

Sunkist beach house. Lake side house 3 bedroom house
10.0 out of 10, Exceptional, (5)
"The house was nice and clean and had every thing on hand that we needed. The host was excellent to deal with. We would definitely stay here again. It’s in a nice quiet neighborhood and the kids enjoyed the park that’s right down the road. "
United States
Deanna P.
$322 nightly
The price is $364
Dec 26 - Dec 27
Total with taxes and fees
Sunkist beach house. Lake side house 3 bedroom house
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top East Prairie Hotel Reviews

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

10/10 Excellent
"When we arrived, check-in was fast and easy, room was 70 degrees, neat and clean. Breakfasts were nice and eating areas were kept clean. There was plenty of food and a good variety. No matter the conditions outside the room was very comfortable. We would definitely stay there again and highly recommend staying there. Check out was simple and quick too. "
Herman 3-night trip
Posted 4 days ago
Sleep Inn at Discovery Park of America

Find out more about East Prairie

Everything you need to know about East Prairie vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the East Prairie vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect East Prairie vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

East Prairie vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in East Prairie. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit East Prairie in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $261 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on East Prairie rentals

At Expedia, we put the best East Prairie vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top East Prairie rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream East Prairie vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around East Prairie. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in East Prairie?

Yes, you can find vacation rentals near the most popular sights in East Prairie, or you can select a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental that East Prairie has to offer?

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters: This vacation home rental near East Prairie is located on a lake and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop.

What can I see and do in East Prairie?

Mississippi River and Big Oak Tree State Park are a couple of lovely local spots to get outside and enjoy nature. In the larger area, you’ll find Central Park and Sikeston Depot Museum.

What are vacation rentals like in East Prairie?

Vacation rentals are privately owned accommodations you can reserve for a few days or a quick weekend in East Prairie. Vacation rentals feature extras like kitchens and laundry facilities so you'll feel right at home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from public hotel elevators and lobbies packed with people while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for family trips.