$110 Cheap Flights from Indianapolis (IND) to San Francisco (SFO)

View $110 flight on Mon, Nov 3, 2025Opens in a new window

Popular airlines from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)

Cheap Flights from Indianapolis to San Francisco (IND-SFO)

Prices were available within the past 7 days and start at $110 for one-way flights and $220 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Dec 4 - Thu, Dec 11
IND
Indianapolis
SFO
San Francisco
$220 Roundtrip, found 2 hours ago
$220
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Thu, Dec 4 from Indianapolis to San Francisco, returning Thu, Dec 11, priced at $220 found 2 hours ago
Delta
Wed, Nov 5 - Sat, Nov 15
IND
Indianapolis
SFO
San Francisco
$244 Roundtrip, found 18 hours ago
$244
Roundtrip
found 18 hours ago
Select Delta flight, departing Wed, Nov 5 from Indianapolis to San Francisco, returning Sat, Nov 15, priced at $244 found 18 hours ago
Frontier Airlines
Mon, Nov 3 - Thu, Nov 13
IND
Indianapolis
SFO
San Francisco
$250 Roundtrip, found 18 hours ago
$250
Roundtrip
found 18 hours ago
Select Frontier Airlines flight, departing Mon, Nov 3 from Indianapolis to San Francisco, returning Thu, Nov 13, priced at $250 found 18 hours ago
Frontier Airlines
Mon, Nov 10 - Tue, Nov 18
IND
Indianapolis
SFO
San Francisco
$250 Roundtrip, just found
$250
Roundtrip
just found
Select Frontier Airlines flight, departing Mon, Nov 10 from Indianapolis to San Francisco, returning Tue, Nov 18, priced at $250 just found
Frontier Airlines
Sat, Nov 15 - Wed, Nov 19
IND
Indianapolis
SFO
San Francisco
$253 Roundtrip, found 2 hours ago
$253
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Sat, Nov 15 from Indianapolis to San Francisco, returning Wed, Nov 19, priced at $253 found 2 hours ago
Frontier Airlines
Thu, Dec 4 - Wed, Dec 10
IND
Indianapolis
SFO
San Francisco
$254 Roundtrip, found 4 hours ago
$254
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Thu, Dec 4 from Indianapolis to San Francisco, returning Wed, Dec 10, priced at $254 found 4 hours ago
Frontier Airlines
Mon, Nov 17 - Thu, Nov 27
IND
Indianapolis
SFO
San Francisco
$255 Roundtrip, found 18 hours ago
$255
Roundtrip
found 18 hours ago
Select Frontier Airlines flight, departing Mon, Nov 17 from Indianapolis to San Francisco, returning Thu, Nov 27, priced at $255 found 18 hours ago
Alaska Airlines
Fri, Dec 5 - Thu, Dec 11
IND
Indianapolis
SFO
San Francisco
$260 Roundtrip, found 4 hours ago
$260
Roundtrip
found 4 hours ago
Select Alaska Airlines flight, departing Fri, Dec 5 from Indianapolis to San Francisco, returning Thu, Dec 11, priced at $260 found 4 hours ago
Southwest Airlines
Mon, Nov 10 - Sat, Nov 15
IND
Indianapolis
SFO
San Francisco
$262 Roundtrip, found 7 hours ago
$262
Roundtrip
found 7 hours ago
Select Southwest Airlines flight, departing Mon, Nov 10 from Indianapolis to San Francisco, returning Sat, Nov 15, priced at $262 found 7 hours ago
United
Sat, Nov 8 - Sat, Nov 15
IND
Indianapolis
SFO
San Francisco
$262 Roundtrip, found 2 hours ago
$262
Roundtrip
found 2 hours ago
Select United flight, departing Sat, Nov 8 from Indianapolis to San Francisco, returning Sat, Nov 15, priced at $262 found 2 hours ago

Find the cheapest month to fly from Indianapolis (IND) to San Francisco (SFO)

February is typically the cheapest month to fly

From $158 - $333 per traveler.

Alternative airports near San Francisco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Norman Y. Mineta San Jose Intl. SJC. Average driving time to city center is 50 minutes. Flights from $398
SJC
Norman Y. Mineta San Jose Intl.
Average driving time to city center50 min
Flights from $398
Select flight to Oakland Intl. OAK. Average driving time to city center is 26 minutes. Flights from $338
OAK
Oakland Intl.
Average driving time to city center26 min
Flights from $338

Frequently asked questions

How much does a flight from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO) cost?
Get a cheap one-way flight from $110 or cheap return flight from $220 from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
The cheapest month to fly from IND to SFO is December, when there's less demand. Off-peak months are usually when airlines offer better prices between these airports.
Which airlines fly direct from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
Board a nonstop flight with United Airlines and go straight from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO).
What is the cheapest airline that flies from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
To find the cheapest airline flying from IND to SFO, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
On average, there's only 1 nonstop flight operating from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO) every day. If this doesn't fit your travel plans, consider flights with layovers. Simply filter your search on Expedia to include one stop or more to discover a better alternative.
What are the most popular departure times for flights from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
Flights between IND and SFO are busiest at 7 AM. If you're after a more relaxed experience and potentially cheaper fares, choose a departure outside the usual busy windows.
What day of the week has the most flights from IND to SFO?
Jet off on a Friday if you're searching for the best choice of flights from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO).
What is the earliest flight from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
The first flight of the day departing from Indianapolis Intl. Airport (IND) is at around 7:33AM UTC-5. Board this plane and you'll land at San Francisco Intl. Airport (SFO) at approximately 9:38AM UTC-8. The overall travel time is 5h 5m.
How long does it take to fly from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
The average flight duration from IND to SFO is 5 hours and 5 minutes, covering a distance of 1,950 mi.
What airline has the least delays from IND to SFO?
United Airlines has the best performance for on-time direct flights from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO), with an on-time rating of 82%. Use the Expedia App to view your flight status before you go and get real-time updates about any trip changes.
What is the best time to fly from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
To reach San Francisco Intl. Airport (SFO) on time, opt for a flight that leaves from Indianapolis Intl. Airport (IND) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for San Francisco from Indianapolis Intl. Airport (IND)?
San Francisco Intl. Airport (SFO) is the only airport in San Francisco with direct flights from Indianapolis Intl. Airport (IND). Browse the available options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO) last-minute?
Booking your ticket from IND to SFO shortly before your journey is typically more expensive. However, if there's some wiggle room with your travel dates and times, you could score a cheap last-minute fare.
Is it cheaper to book an IND to SFO flight and hotel package?
You'll generally save money by securing an IND to SFO flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. Once you've selected your preferred flights and accommodations, consider adding extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from Indianapolis Intl. Airport (IND) to San Francisco Intl. Airport (SFO)?
Generally, it's possible to cancel or reschedule your IND to SFO flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Indianapolis Intl.
Destination airport
San Francisco Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, Southwest Airlines, Sun Country Airlines, United
Roundtrip price
$220
Distance
1939 mi
Average flight time
3 hours 26 mins

Book with confidence

Indianapolis to San Francisco Flights

The cheapest times to fly from Indianapolis to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Indianapolis to San Francisco are during the month of December. You can find some of the cheapest flights from Indianapolis to San Francisco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Indianapolis to San Francisco

Sunday is one of the best days to book for cheap flights from Indianapolis to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Indianapolis to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Indianapolis to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $110 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Indianapolis to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Indianapolis to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Indianapolis to San Francisco Flights

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*Available to One Key members.