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Lodging near Cape Romain National Wildlife Refuge, South Carolina

Stay close to nature from $92

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Compare 1,925 hotels close to Cape Romain National Wildlife Refuge with room rates, reviews, and availability. Most hotels are fully refundable.

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

4.0 star property
20.6 mi from Cape Romain National Wildlife Refuge
8.8 out of 10, Excellent, (1003)
"Great Stay!"
United States
Doug
$197 nightly
The price is $225
Dec 7 - Dec 8
Total with taxes and fees
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

2.5 star property
23.2 mi from Cape Romain National Wildlife Refuge
9.0 out of 10, Wonderful, (1000)
"Great place to stay!!!"
United States
Fredrick
$83 nightly
The price is $93
Jan 4 - Jan 5, 2026
Total with taxes and fees
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

2.5 star property
22.8 mi from Cape Romain National Wildlife Refuge
9.0 out of 10, Wonderful, (1001)
"Everything about my stay here has been a delight, clean room, professional & friendly staff "
United States
John
$83 nightly
The price is $94
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Tru by Hilton Mt Pleasant Charleston

2.5 star property
24.5 mi from Cape Romain National Wildlife Refuge
9.2 out of 10, Wonderful, (1453)
"It was a great hotel!"
United States
Alashia
$81 nightly
The price is $92
Dec 16 - Dec 17
Total with taxes and fees
Tru by Hilton Mt Pleasant Charleston

Wicklow Hall

2.0 star property
17.1 mi from Cape Romain National Wildlife Refuge
$353 nightly
The price is $392
Dec 9 - Dec 10
Total with taxes and fees
Wicklow Hall

The Palms Oceanfront Hotel

3.5 star property
23.5 mi from Cape Romain National Wildlife Refuge
8.2 out of 10, Very Good, (1056)
"Great location and clean rooms!"
United States
Kristen
$112 nightly
The price is $128
Jan 4 - Jan 5, 2026
Total with taxes and fees
The Palms Oceanfront Hotel

Hyatt Place Mount Pleasant Towne Centre

3.0 star property
23.5 mi from Cape Romain National Wildlife Refuge
9.0 out of 10, Wonderful, (1000)
"Nice place"
United States
Marcelle
$122 nightly
The price is $136
Dec 8 - Dec 9
Total with taxes and fees
Hyatt Place Mount Pleasant Towne Centre

Home2 Suites By Hilton Mt Pleasant Charleston

3.0 star property
23.8 mi from Cape Romain National Wildlife Refuge
8.8 out of 10, Excellent, (989)
"The staff were great "
United States
kamran
$95 nightly
The price is $108
Dec 11 - Dec 12
Total with taxes and fees
Home2 Suites By Hilton Mt Pleasant Charleston

Cambria Hotel Mount Pleasant – Charleston

3.0 star property
24.8 mi from Cape Romain National Wildlife Refuge
9.4 out of 10, Exceptional, (1786)
"Nice hotel for the price"
United States
James
$95 nightly
The price is $107
Dec 21 - Dec 22
Total with taxes and fees
Cambria Hotel Mount Pleasant – Charleston

Residence Inn by Marriott Charleston Mount Pleasant

3.0 star property
23.2 mi from Cape Romain National Wildlife Refuge
8.8 out of 10, Excellent, (183)
"Property was quiet and clean. It was convenient to dining and shopping options. Pool was very well maintained and breakfast was well-stocked and excellent each morning. "
United States
Holly
$110 nightly
The price is $124
Dec 14 - Dec 15
Total with taxes and fees
Residence Inn by Marriott Charleston Mount Pleasant

Wild Dunes Resort – Residences at Sweetgrass

3.5 star property
20.6 mi from Cape Romain National Wildlife Refuge
8.6 out of 10, Excellent, (175)
"We come here often"
United States
Joseph
$198 nightly
The price is $226
Dec 8 - Dec 9
Total with taxes and fees
Wild Dunes Resort – Residences at Sweetgrass

Hyatt House Charleston / Mount Pleasant

3.5 star property
24.7 mi from Cape Romain National Wildlife Refuge
9.2 out of 10, Wonderful, (1000)
"Good value and great location."
United States
Howard
$107 nightly
The price is $121
Jan 3 - Jan 4, 2026
Total with taxes and fees
Hyatt House Charleston / Mount Pleasant

Comfort Suites at Isle Of Palms Connector

2.5 star property
23.2 mi from Cape Romain National Wildlife Refuge
8.2 out of 10, Very Good, (1011)
"The staff was friendly and the room was exceptionally clean. "
United States
RAYMOND
$86 nightly
The price is $97
Jan 4 - Jan 5, 2026
Total with taxes and fees
Comfort Suites at Isle Of Palms Connector

DoubleTree by Hilton Charleston Mount Pleasant

4.0 star property
25.2 mi from Cape Romain National Wildlife Refuge
9.2 out of 10, Wonderful, (1013)
"Room was nice and staff was very friendly."
United States
Viorel
$90 nightly
The price is $101
Dec 21 - Dec 22
Total with taxes and fees
DoubleTree by Hilton Charleston Mount Pleasant

Homewood Suites by Hilton Charleston - Mt Pleasant

3.0 star property
23.1 mi from Cape Romain National Wildlife Refuge
8.4 out of 10, Very Good, (1005)
"Courteous staff and great location"
United States
Loushon
$105 nightly
The price is $119
Dec 10 - Dec 11
Total with taxes and fees
Homewood Suites by Hilton Charleston - Mt Pleasant

Courtyard by Marriott Charleston Mount Pleasant

3.0 star property
24.5 mi from Cape Romain National Wildlife Refuge
8.8 out of 10, Excellent, (1000)
"We had a very restful stay. The lady that checked us in was very nice. The room was very clean and the beds were comfortable. "
United States
Kathryn
$101 nightly
The price is $114
Dec 14 - Dec 15
Total with taxes and fees
Courtyard by Marriott Charleston Mount Pleasant

Seaside Inn Oceanfront

2.5 star property
23.6 mi from Cape Romain National Wildlife Refuge
7.6 out of 10, Good, (1001)
"Great place to stay!!! "
United States
Stephanie
$109 nightly
The price is $125
Dec 7 - Dec 8
Total with taxes and fees
Seaside Inn Oceanfront

TownePlace Suites Charleston Mt. Pleasant

3.0 star property
25.2 mi from Cape Romain National Wildlife Refuge
9.0 out of 10, Wonderful, (523)
"Great place to stay. Dog friendly. "
United States
Gabriela
$110 nightly
The price is $124
Dec 13 - Dec 14
Total with taxes and fees
TownePlace Suites Charleston Mt. Pleasant
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Cape Romain National Wildlife Refuge Hotel Reviews

Hotels near other Cape Romain National Wildlife Refuge attractions

Frequently asked questions

What's the area like around Cape Romain National Wildlife Refuge?
If you're planning to come to the area to visit Cape Romain National Wildlife Refuge, take some time to see the rest of the sights while you're in town. If you're looking for a convenient place to stay, you might search for properties close to public transportation so it's easy to get around.
What's the best hotel to stay close to Cape Romain National Wildlife Refuge?
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn is one of the top choices for your stay based on our traveler data, and this resort offers 5 outdoor pools and a full-service spa. You'll find it 20.6 mi (33.2 km) from Cape Romain National Wildlife Refuge. Another good choice is Rest & relax at your home away from home! Gorgeous guest house near Charleston!, located 18.1 mi (29.2 km) away.
If I need to cancel the hotel reservation for my stay near Cape Romain National Wildlife Refuge, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review top deals close to Cape Romain National Wildlife Refuge.
Where can I learn more about changing or cancelling my trip in the area near Cape Romain National Wildlife Refuge?
To find more details about changing or cancelling your stay near Cape Romain National Wildlife Refuge, go to https://www.expedia.com/service/.

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