Uptown - Upper Duval, FL
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
4.5/5(3,182 reviews)
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
4/5(980 reviews)
Head to the southernmost beach of the continental United States to relax and swim in the waters where famous writer Tennessee Williams once took his daily swim.
Key West Butterfly and Nature Conservatory
4.5/5(760 reviews)
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Florida: Key West Overseas Highway App-Based Driving Audio Tour
$17
per traveler
80% of travellers recommend
Key West’s Old Town Treasures: A Self-Guided Audio Tour
$15
per adult
Florida Key West Self-Guided Walking Audio Tour Via App
$10
per traveler
Southernmost Key West History and Culture Small-Group Walking Tour
$40
per adult
An Audio Guide of Key West’s Journey From Village to Micro State
$12
per adult
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
1319 Duval Street, Key West, FL
$237 nightly
The price is $266 total per night from Oct 13 to Oct 14
$266 total
Oct 13 - Oct 14
Total with taxes and fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,771 reviews)
"Good location"
Reviewed on Sep 23, 2025
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street, Key West, FL
$257 nightly
The price is $289 total per night from Oct 5 to Oct 6
$289 total
Oct 5 - Oct 6
Total with taxes and fees
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,013 reviews)
"Great staff, view and food!"
Reviewed on Sep 24, 2025
Southwinds Motel
1321 Simonton Street, Key West, FL
$144 nightly
The price is $163 total per night from Oct 1 to Oct 2
$163 total
Oct 1 - Oct 2
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,185 reviews)
"The room was nice, & the area was fairly good. Near the Southernmost Point marker. Only downside was the water pressure was pretty weak."
Reviewed on Sep 22, 2025
The Southernmost Inn - Adults Only
525 United Street, Key West, FL
$123 nightly
The price is $138 total per night from Sep 28 to Sep 29
$138 total
Sep 28 - Sep 29
Total with taxes and fees
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,176 reviews)
"Handy for popular local area"
Reviewed on Sep 20, 2025
Santa Maria Suites
1401 Simonton St, Key West, FL
$295 nightly
The price is $332 total per night from Sep 29 to Sep 30
$332 total
Sep 29 - Sep 30
Total with taxes and fees
Stay at this 4-star resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. ...
9.6/10 Exceptional! (1,007 reviews)
"The suite we stayed in was just like the pictures. I would stay there again the next time I go to the keys. Karen"
Reviewed on Sep 21, 2025
Kona Kai Oasis
630 South Street, Key West, FL
$119 nightly
The price is $134 total per night from Sep 29 to Sep 30
$134 total
Sep 29 - Sep 30
Total with taxes and fees
Stay at this 3-star guesthouse in Key West. Enjoy free WiFi, free parking, and a garden. Our guests praise the helpful staff in our reviews. Popular attractions ...
8/10 Very Good! (556 reviews)
"Not many towels and the fridge was dirty"
Reviewed on Sep 6, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Other neighborhoods around Uptown - Upper Duval
Old Town Key West
4.5/5(226 area reviews)
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Bahama Village
5/5(38 area reviews)
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.
Key West Historic District
4.5/5(4,033 area reviews)
Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Saint Mary Star of the Sea, some noteworthy sights in the nearby area.
Uptown - Upper Duval, FL
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