Find all hotels by Independent in Prairie Home, MO from $75

Start date: Check-in selected.
To Date
End date: Check-out

Check prices for these dates

Tonight
Dec 13 - Dec 14
Tomorrow
Dec 14 - Dec 15
Next weekend
Dec 19 - Dec 21
In two weeks
Dec 26 - Dec 28

Our top choices for Prairie Home Independent

Indoor spa tub
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia
2.5 star property
Columbia
8.6 out of 10, Excellent, (1351)
"Great Stay"
United States
chasity
$91 nightly
The price is $103
Dec 21 - Dec 22
Total with taxes and fees
Stoney Creek Hotel Columbia
Desk, free WiFi, bed sheets, alarm clocks
Birch Hill Suites Columbia

Birch Hill Suites Columbia

Birch Hill Suites Columbia
2.0 star property
Columbia
6.4 out of 10, (457)
"The staff was very nice and helpfull the place has everything youd need"
United States
John
$66 nightly
The price is $75
Dec 14 - Dec 15
Total with taxes and fees
Birch Hill Suites Columbia
Reception
Midway Budget Inn

Midway Budget Inn

Midway Budget Inn
2.5 star property
Columbia
6.0 out of 10, (119)
"Fantastic! "
United States
Al
$80 nightly
The price is $85
Dec 14 - Dec 15
Total with taxes and fees
Midway Budget Inn
Exterior
By The Way Motel Columbia

By The Way Motel Columbia

By The Way Motel Columbia
2.0 star property
Columbia
2.8 out of 10, (5)
"I liked Patrick the manager always a available to help … but not the best part of town"
United States
Michael
$100 nightly
The price is $114
Dec 20 - Dec 21
Total with taxes and fees
By The Way Motel Columbia
Garden
Boonville Luxury Lodging

Boonville Luxury Lodging

Boonville Luxury Lodging
4.0 star property
Boonville
10.0 out of 10, Exceptional, (40)
"Everything is absolutely fantastic!"
United States
Rita
$187 nightly
The price is $212
Dec 31 - Jan 1, 2026
Total with taxes and fees
Boonville Luxury Lodging
Fridge, microwave, oven, stovetop
Katy Trail Pull Off

Katy Trail Pull Off

Katy Trail Pull Off
Boonville
9.6 out of 10, Exceptional, (99)
"Great home, quiet neighborhood, and comfy beds. Perfect home for our stay and we will stay again. "
United States
Samantha H.
$165 nightly
The price is $178
Dec 14 - Dec 15
Total with taxes and fees
Katy Trail Pull Off
Outdoor dining
Unique traincar stay at the Katy Caboose!

Unique traincar stay at the Katy Caboose!

Unique traincar stay at the Katy Caboose!
Hartsburg
9.4 out of 10, Exceptional, (10)
"We loved the 3 taverns in town. Great vibe in a tiny town. "
United States
Dusty
$167 nightly
The price is $176
Dec 21 - Dec 22
Total with taxes and fees
Unique traincar stay at the Katy Caboose!
Microwave, oven, stovetop, dishwasher
Upscale 2-bedroom luxury loft in vibrant downtown Columbia, MO, in The District

Upscale 2-bedroom luxury loft in vibrant downtown Columbia, MO, in The District

Upscale 2-bedroom luxury loft in vibrant downtown Columbia, MO, in The District
2.0 star property
Columbia
10.0 out of 10, Exceptional, (1)
"Amazing loft condo in an amazing location, heart of downtown Columbia. Highly recommend"
United States
Adam F.
Upscale 2-bedroom luxury loft in vibrant downtown Columbia, MO, in The District
Dining
Near Mizzou & Univ Hosp • Firepit • BBQ • Games

Near Mizzou & Univ Hosp • Firepit • BBQ • Games

Near Mizzou & Univ Hosp • Firepit • BBQ • Games
2.0 star property
Columbia
10.0 out of 10, Exceptional, (1)
"This was a nice VRBO. All king size beds. We were there for a FB game and it is convenient to Faurot. *For what it's worth...There is no pool - it kept mentioning this on the review. "
United States
John C.
Near Mizzou & Univ Hosp • Firepit • BBQ • Games
Fridge, microwave, oven, stovetop
Spacious & Cozy near Downtown ~ HotTub ~ Game Room

Spacious & Cozy near Downtown ~ HotTub ~ Game Room

Spacious & Cozy near Downtown ~ HotTub ~ Game Room
Columbia
10.0 out of 10, Exceptional, (55)
"The house was great for all of us to stay together for our family reunion. "
United States
Anonymous traveler
$611 nightly
The price is $640
Dec 14 - Dec 15
Total with taxes and fees
Spacious & Cozy near Downtown ~ HotTub ~ Game Room
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Prairie Home Hotel Reviews

Hilton Garden Inn Columbia

Hilton Garden Inn Columbia

10/10 Excellent
"The front desk people were very nice. Welcoming and caring. We had an issue. It was taken care of right away. Staff is amazing . "
Lisa 1-night trip
Posted 1 day ago
Hilton Garden Inn Columbia

Explore a world of travel with Expedia