Residence Inn Durham McPherson/Duke University Medical Cntr

Hotel with free breakfast, 5-minute walk to Duke University

Choose dates to view prices

Where to?

Dates

November 2025

2

December 2025

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub) | 1 bedroom, in-room safe, desk, laptop workspace

Full-size fridge, microwave, stovetop, dishwasher

Residence Inn Durham McPherson/Duke University Medical Center offers a refreshed retreat with practical comforts. Enjoy a to-go breakfast, relax by the lobby fireplace, and request complimentary grocery shopping. WiFi in all rooms and an area shuttle make attractions accessible.

Wonderful

Popular amenities

Bar
Kitchen
Parking available
Housekeeping

Room options

Check availability for these dates

Tonight

Nov 2 - Nov 3

Tomorrow

Nov 3 - Nov 4

All rooms

1 bed

2 beds

3+ beds

Showing 10 of 10 rooms

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

Wonderful

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

469 sq ft
1 bedroom
Sleeps 3
1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed, Non Smoking

Excellent

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

480 sq ft
Sleeps 3
1 King Bed and 1 Double Sofa Bed

Studio, 1 Queen Bed with Sofa bed, Non Smoking

Exceptional

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

424 sq ft
Sleeps 3
1 Queen Bed and 1 Double Sofa Bed

Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

Excellent

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

Sleeps 3
1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

478 sq ft
Sleeps 3
1 King Bed and 1 Double Sofa Bed

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

479 sq ft
Sleeps 3
1 King Bed and 1 Double Sofa Bed

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

479 sq ft
Sleeps 3
1 King Bed and 1 Double Sofa Bed

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

426 sq ft
Sleeps 3
1 Queen Bed and 1 Double Sofa Bed

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

Sleeps 5
2 Queen Beds and 1 Double Sofa Bed

Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

Exceptional

Highlights

Separate sitting area

Air conditioning

Kitchen

Full-sized refrigerator/freezer

Dining table

Dishwasher

Smart TV

Renovated in 2024

Sleeps 3
1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

About the neighborhood

1108 West Main Street, Durham, NC, 27701

What's nearby

Duke University - 3 min walk - 0.2 miles
Durham Bulls Athletic Park - 16 min walk - 0.9 miles
Durham Performing Arts Center - 17 min walk - 0.9 miles
Duke University Hospital - 2 min drive - 1.7 miles
Cameron Indoor Stadium - 6 min drive - 2.5 miles

Getting around

Durham Station - 8 min walk
Raleigh-Durham International Airport (RDU) - 19 min drive

Restaurants

‪The Can Opener - ‬7 min walk
‪Ramblers - ‬7 min walk
‪Fonda Lupita - ‬3 min walk
‪Emmy Squared - ‬5 min walk
‪Clouds Brewcade + Kitchen - ‬4 min walk

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

Hotel remodeled in 2024 and located near Duke University

Consider a stay at Residence Inn Durham McPherson/Duke University Medical Cntr and take advantage of free to-go breakfast, a free grocery shopping service, and a terrace. In addition to dry cleaning/laundry services and a fireplace in the lobby, guests can connect to free in-room WiFi.

Other perks include:

A free area shuttle, self parking (surcharge), and express check-out
Express check-in, wedding services, and smoke-free premises
Coffee/tea in the lobby, luggage storage, and concierge services
Guest reviews speak highly of the helpful staff

Room features

All 147 rooms include comforts such as laptop-friendly workspaces and air conditioning, in addition to thoughtful touches like free WiFi and desk chairs.

Extra conveniences in all rooms include:

Recycling and LED light bulbs
Shower/tub combinations, free toiletries, and hair dryers
32-inch Smart TVs with Netflix and premium channels
Wardrobes/closets, separate sitting areas, and kitchens

Similar properties

Pet friendly
Free WiFi
Restaurant
Air conditioning

$118 nightly

Nov 23 - Nov 24

Total with taxes and fees

Property amenities

Internet

Available in all rooms: Free WiFi
Available in some public areas: Free WiFi

Parking and transportation

Free area shuttle
Self parking on site (USD 15 per day)
Wheelchair-accessible parking available

Food and drink

Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
A bar/lounge
Coffee and tea in common areas

Things to do

24-hour gym

Family friendly

Dining table
Free area shuttle
Grocery/convenience store
In-room full-sized refrigerator/freezer
In-room kitchen
In-room microwave
Laundry facilities

Conveniences

24-hour front desk
Free newspapers in lobby
Grocery/convenience store
Laundry facilities
Luggage storage
Safe at front desk

Guest services

Change of bedsheets (on request)
Change of towels on request
Concierge services
Dry cleaning/laundry service
Free grocery shopping service
Housekeeping (daily)
Wedding services

Business services

2,530 square feet of conference space
Business center
Computer station

Outdoors

Terrace

Accessibility

If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
7 accessible parking spaces
Assistive listening devices in meeting rooms
Braille/raised signage
Elevator (42 inch wide door)
Hardwood flooring in room
Lever door handles
Thin carpet in room
Visual alarms in hallways
Wheelchair accessible (may have limitations)
Wheelchair-accessible business center
Wheelchair-accessible gym
Wheelchair-accessible lounge
Wheelchair-accessible parking
Wheelchair-accessible path of travel
Wheelchair-accessible path to elevator
Wheelchair-accessible registration desk (34 inches high)
Wheelchair-accessible restaurant

More

5 floors
Banquet hall
Biodegradable coffee stirrers available
Built in 2015
Comprehensive recycling policy
Double-glazed windows
Fireplace in lobby
No plastic coffee stirrers
No plastic drinking straws
Renovated entire property - April 2024
Smoking not allowed
Vegan dining options
Vegetarian breakfast available
Vegetarian dining options

Room amenities

Bedroom

Bedsheets provided
Blackout drapes

Bathroom

Free toiletries
Hair dryer
Shower/bathtub combination
Towels provided

Entertainment

32-inch smart TV with premium cable channels
Netflix
Pay movies

Food and drink

Coffee/tea maker
Cookware, dishware, and utensils
Dining table
Dishwasher
Full-sized refrigerator/freezer
Kitchen
Microwave
Stovetop

More

Air conditioning (climate-controlled)
Desk
Desk chair
Energy-saving switches in guestrooms
Free local calls
Iron/ironing board
Laptop workspace
LED lighting
Phone
Recycling
Safe
Separate sitting area
Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight

Express check-in available

Minimum check-in age: 21

Check-out

Check-out before noon

Contactless check-out available

Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100.00 per pet (varies based on length of stay)

Service animals are welcome, and are exempt from fees

2 total (up to 100 lbs per pet)

Restrictions apply; for more information contact the property at the number on the booking confirmation

Children and extra beds

Children are welcome

Rollaway/extra beds are not available

Cribs (infant beds) are not available

Property payment types

Important information

Optional extras

Self parking fee: USD 15 per day
Pet fee: USD 100.00 per pet (varies based on length of stay)
Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy

Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges

Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed

This property accepts credit cards; cash is not accepted

Safety features at this property include a carbon monoxide detector and a smoke detector

This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)

We should mention

Guests under 18 years old are not allowed in the fitness facility, and guests under 18 years old are only allowed in the swimming pool and fitness facility with adult supervision

This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel

Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn McPherson/Duke University Medical Cntr

Residence Inn McPherson/Duke University Medical Cntr Hotel

Residence Inn McPherson/Duke University Medical Cntr

Frequently asked questions

Is Residence Inn Durham McPherson/Duke University Medical Cntr pet-friendly?

Yes, Residence Inn Durham McPherson/Duke University Medical Cntr allows pets (limit 2 total) with a maximum weight of up to 100 lbs per pet. There's a fee of USD 100.00 per pet, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.

How much does it cost to stay at Residence Inn Durham McPherson/Duke University Medical Cntr?

As of Nov 2, 2025, prices found for a 1-night stay for 2 adults at Residence Inn Durham McPherson/Duke University Medical Cntr on Nov 23, 2025 start from $131.13, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

How much is parking at Residence Inn Durham McPherson/Duke University Medical Cntr?

Self parking is available for USD 15 per day.

What time is check-in at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-in start time: 3 PM; Check-in end time: midnight.

What time is check-out at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-out is at noon.

Where is Residence Inn Durham McPherson/Duke University Medical Cntr located?

Located in Downtown Durham, this hotel is within a 10-minute walk of Brightleaf Square and Duke University. Carolina Theatre and Durham Convention Center are also within 15 minutes. Durham Station is 8 minutes by foot.

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Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

9.2

Wonderful

9.4/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.4/10

Property conditions & facilities

9.0/10

Eco-friendliness

8/10 Good

James

Oct 13, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Nice hotel for the price. Good location. Big rooms. Quiet. Easy parking. Could be a little cleaner.

Stayed 2 nights in Oct 2025

8/10 Good

nicole

Oct 26, 2025

Liked: Cleanliness, staff & service, property conditions & facilities

Clean room. Lighting in bathroom needs to be better.

Stayed 1 night in Oct 2025

10/10 Excellent

Derek

Aug 5, 2025

Liked: Cleanliness, staff & service, property conditions & facilities

Was very nice. The staff was very polite when we arrived.

Stayed 1 night in Aug 2025

10/10 Excellent

LaMeesha

Jun 26, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.

Stayed 8 nights in Jun 2025

10/10 Excellent

Timmy

Jun 9, 2025

Liked: Cleanliness, amenities, property conditions & facilities

It was very clean and the staff was excellent. The stay was really good. The attendant was great at checking.

Stayed 1 night in Jun 2025

10/10 Excellent

Wendy

Sep 19, 2024

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Clean, friendly, great location.

Stayed 1 night in Sep 2024

8/10 Good

Lourdes Dolores

Jul 8, 2025

Liked: Cleanliness, property conditions & facilities, room comfort

Wasteful shower design

The room was clean and comfortable and the gym was good. However, I gave the hotel 3 stars because the shower lets out so much water that it is actually wasting water. There's no door for the shower, so when you bathe, the water streams out of the shower and onto the bathroom floor. So much water streams out that I had to place the bathmat 12 inches away from the shower entrance so that it wouldn't get wet.

Stayed 10 nights in Jun 2025

6/10 Okay

Tian

May 30, 2025

Disliked: Staff & service, amenities

It smelled musky and like urine in our room and much of the facility just smelled like cleaning supplies. The wifi wasn’t great in the room. The location is decently close to Duke, but the immediate area is at a street intersection right by a gas station. There was plenty of parking for pay by mobile 15$.

Stayed 1 night in May 2025

10/10 Excellent

Jackson

Nov 25, 2022

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Nice clean room,good breakfast and great staff.

Stayed 4 nights in Nov 2022

10/10 Excellent

Mustafa

Nov 30, 2023

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

comfortable stay

Stayed 3 nights in Nov 2023

10/10 Excellent

Karl

May 26, 2023

Liked: Cleanliness, staff & service, property conditions & facilities

The staff was very friendly and helpful!

Stayed 2 nights in May 2023

10/10 Excellent

Lalita

Sep 3, 2024

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Excellent

Loved how clean and big the room was.

Stayed 3 nights in Aug 2024

10/10 Excellent

Luis

Feb 19, 2023

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Extremely convenient for the purpose of my visit

Stayed 6 nights in Feb 2023

10/10 Excellent

eleshia A

Jul 5, 2022

Liked: Cleanliness, staff & service, property conditions & facilities

I like everything about the hotel

Stayed 1 night in Jul 2022

10/10 Excellent

Adrian

May 4, 2024

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Wonderful experience

Stayed 1 night in May 2024

8/10 Good

Deborah

Dec 1, 2023

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Amazing room, just skip the breakfast

The room itself is exceptional and perfect for a business stay or writing retreat, especially as the kitchen allows you to cook and stay focused on work without having to leave the room. Location is also great if you do want to explore restaurants and Duke. Only complaint is that their breakfast is mediocre at best.

Stayed 2 nights in Nov 2023

10/10 Excellent

Milton

Jul 25, 2022

Love it

The hotel was very nice. Customer service was good. The room was very clean and up to date.

Stayed 1 night in Jul 2022

10/10 Excellent

Christine

Sep 2, 2024

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Went to visit my daughter who is attending Duke. Great place to stay. Rooms were nice and clean. Very comfortable. The bar has signs for hours that were not accurate. A few night I was there I was told staff left “because it was slow”. This was at 7:00 at night. Seemed weird.

Stayed 6 nights in May 2024

8/10 Good

Deborah

Apr 20, 2024

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Property under construction so super noisy all day.

Stayed 3 nights in Apr 2024

2/10 Terrible

Michael

Dec 6, 2024

Disliked: Cleanliness, staff & service, property conditions & facilities, room comfort

Long drive to have my room given away.

After confirming my stay with the Residence Inn Durham by checking in online, then email exchange just hours before my arrival stating “I am on my way and would be there in 2hrs”- then the hotel acknowledging that check in… I got to the front desk at 6:10pm to find out I no longer had a room and was being re-booked at a different, lesser quality hotel 10 mins away. (After driving 9hrs to get there). Utterly ridiculous and I’ll never book a room with them again.

Stayed 1 night in Dec 2024

10/10 Excellent

Paul

Apr 19, 2024

Liked: Cleanliness, staff & service, amenities

Didn't like all the noisy remodeling going on.

Stayed 1 night in Apr 2024

6/10 Okay

Rafael

Aug 14, 2023

Liked: Cleanliness

"Refresh the room" failed

Good location and clean property. However, although requested to clean the room every other day, as they suggest, we have the room "refreshed" only one time in a 7-day stay

Stayed 6 nights in Aug 2023

8/10 Good

Eileen

Oct 24, 2022

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

FYI: parking costs

Nice place. Parking is NOT free despite Hotels.com saying it is. Desk clerk said Hotels.com has been contacted numerous times to delete reference to free parking. Website says parking costs $12/day. Pool is small but looks nice. Breakfast is nicer than most hotels provide.

Stayed 1 night in Oct 2022

10/10 Excellent

Anthony

Jul 25, 2022

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Loved it here. Excellent property and rooms. Very well managed and the front desk lady was so kind and helpful. My saving grace after a rough week of work. Though I did have issues with the Wifi going in and out constantly. That could be improved for room 104. As I could not watch internet TV and my calls would drop out. Other than that I will definitely be back should the need arise!

Stayed 4 nights in Jul 2022

10/10 Excellent

Jill

Aug 15, 2024

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

I bought travel insurance for the first time ever from Expedia thinking it would cover any schedule changes I had. I let Expedia know well before the last day of my trip that I wanted to cancel my 3rd night and they said it was too late and I was charged anyway. Expedia is blaming the hotel but Expedia was where I paid for the hotel and the insurance so this has nothing to do with the hotel. Really disappointed with Expedia but the hotel was great.

Stayed 3 nights in Aug 2024