Seneca Vacations from $439

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The Latest Seneca vacation packages

Price found within the past 48 hours. Click for updated prices.
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Comfort Inn & Suites Greer - Greenville
Hotel Hartness
La Quinta Inn & Suites by Wyndham Greenville Haywood
Mint House Greenville - Downtown
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Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca

Seneca Hotel Deals

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $137 total per night from Aug 22 to Aug 23
$137 total
Aug 22 - Aug 23
Total includes taxes and fees
9/10 Wonderful! (991 reviews)
"Stayed in one BR unit with full kitchen which was great! Blender worked perfectly for our daiquiris. It was a hot & sunny weekend. Pool was clean & plenty of chairs. Lobby & outdoor sitting areas nice & comfy during this busy weekend too. Would definitely recommend this resort. Can walk to shopping ..."

Reviewed on Aug 18, 2025

Lakeside Lodge Clemson
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd, Seneca, SC
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $98 total per night from Aug 31 to Sep 1
$98 total
Aug 31 - Sep 1
Total includes taxes and fees
7.8/10 Good! (632 reviews)
Nice hotel!
"Nice clean, comfortable stay with a great breakfast."

Reviewed on Aug 19, 2025

Quality Inn Seneca Clemson Area US-123
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street, Seneca, SC
$121 nightly
The price is $133 total per night from Aug 24 to Aug 25
$133 total
Aug 24 - Aug 25
Total includes taxes and fees
9.2/10 Wonderful! (626 reviews)
"Great stay except for the pillows. They were like thin paper couldn’t get comfortable besides that everything was great. I would just bring my own pillow next time."

Reviewed on Aug 17, 2025

Hampton Inn & Suites Seneca-Clemson Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Seneca vacation package cost?
You'll find cheap prices from $439 on Expedia for your Seneca break. However, factors like the season, choice of hotel and length of stay will determine how much your vacation to Seneca costs.
What are the cheapest months to go to Seneca?
You can typically find lower rates and better availability in September, October and December. Browse our cheap Seneca vacation packages and you could land some great off-season discounts.
How many days is enough for Seneca?
Usually, a handful of days is enough to tick off the top attractions during your Seneca vacation. But if you prefer to have more time to rest or go on day tours, consider extending your itinerary.
How to find the best Seneca package deals?
Start your search for a Seneca package deal by entering your destination and travel dates under our "Packages" tab. Then add some filters, like "Guest rating" and "Property type," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the perfect Seneca package deal right away, simply tweak your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Seneca escape underway.
Is it cheaper to book a Seneca vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, car rental and flight into one great-value price and you could save hundreds of dollars. You'll generally get a better deal than booking each component separately. And you'll still enjoy the freedom to create a personalized Seneca vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Seneca?
If you've got your Seneca travel dates locked in, book as early as you can to grab some fantastic deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment getaways? Our last-minute deals are great for traveling on a whim.
Does Expedia offer Book Now, Pay Later Seneca vacation packages?
Set off on your perfect escape to Seneca with help from our Book Now, Pay Later vacations. There's no need to scrimp and save or wait until your next payday — we've joined forces with online lender Affirm to give you financial flexibility. Our vacation packages with payment plans allow you to spread the total cost over 3, 6 or 12 months. With no hidden charges or late payment fees, you can easily stay on budget and snap up cheap deals before they disappear.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.