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Find Resorts & Hotels with Spas in Seneca, SC

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Top Seneca Resorts & Hotels with Spas

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Recommended hotels in Seneca

Lakeside Lodge Clemson
2.5 star property
9.0 out of 10, Wonderful, (1004)
"Very beautiful place to stay"
United States
Steven
$123 nightly
The price is $135
Oct 28 - Oct 29
Total with taxes and fees
Lakeside Lodge Clemson
Quality Inn Seneca Clemson Area US-123
2.5 star property
8.0 out of 10, Very Good, (651)
"Friendly check in, clean room."
United States
connie
$91 nightly
The price is $99
Nov 3 - Nov 4
Total with taxes and fees
Quality Inn Seneca Clemson Area US-123
Best Western Seneca-Clemson
2.5 star property
8.4 out of 10, Very Good, (624)
"Convenient for Clemson visits."
United States
Kathleen
$85 nightly
The price is $94
Nov 3 - Nov 4
Total with taxes and fees
Best Western Seneca-Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
9.4 out of 10, Exceptional, (199)
"Nice hotel by the lake"
United States
Mike
$120 nightly
The price is $132
Nov 23 - Nov 24
Total with taxes and fees
Fairfield Inn & Suites Seneca Clemson Univ Area
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
9.8 out of 10, Exceptional, (43)
"The place was absolutely magnificent."
United States
David
$169 nightly
The price is $186
Oct 28 - Oct 29
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Tru by Hilton Seneca Clemson
2.5 star property
9.2 out of 10, Wonderful, (777)
"Clean room, staff was great, will always stay at this hotel in Clemson. Best place to stay!"
United States
Gretchen
$106 nightly
The price is $116
Nov 2 - Nov 3
Total with taxes and fees
Tru by Hilton Seneca Clemson
Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
9.4 out of 10, Exceptional, (648)
"Great place to stay"
United States
Jose
$137 nightly
The price is $151
Nov 27 - Nov 28
Total with taxes and fees
Hampton Inn & Suites Seneca-Clemson Area
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC
10.0 out of 10, Exceptional, (8)
"The location was perfect for what we needed last minute. Our hosts and hosts family were so friendly and welcoming. We absolutely adored the homestead and market that was set up and our son loved having all the animals around. Waking up to the chickens and the sunrise was the perfect start to each day!"
United States
Emily E.
$189 nightly
The price is $208
Oct 28 - Oct 29
Total with taxes and fees
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC
Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
6.8 out of 10, (708)
"The rooms have been renovated it was nice and clean especially for the price. "
United States
Sherri
$74 nightly
The price is $81
Nov 3 - Nov 4
Total with taxes and fees
Days Inn by Wyndham Seneca / Clemson Area
Boutique hotel in historic downtown Seneca. Room #4, King bed.
9.6 out of 10, Exceptional, (14)
"Great location, updated, well decorated, and very comfy. Great communication with property manager. "
United States
Ali R.
$194 nightly
The price is $210
Oct 28 - Oct 29
Total with taxes and fees
Boutique hotel in historic downtown Seneca. Room #4, King bed.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Seneca

Top Seneca attractions for a relaxing vacation

Seneca, South Carolina, offers an enticing blend of natural beauty and relaxation, making it a perfect spot for travelers seeking hotels with spas. Explore the stunning Lake Hartwell, where you can indulge in a leisurely afternoon of fishing or boating, followed by a soothing massage at a nearby spa. The picturesque Oconee State Park provides hiking trails that lead you through lush forests and serene waterfalls, ideal for a refreshing retreat after a day of wellness. For a unique experience, visit the South Carolina Botanical Garden, where you can stroll through beautifully curated landscapes and enjoy the tranquility of nature, setting the perfect mood for a day of pampering. Don’t miss out on the charming downtown area, filled with local boutiques and cafes that invite you to unwind. Consider staying in a hotel near the lakefront where you can enjoy stunning sunset views while planning your next spa treatment, ensuring a restful and rejuvenating getaway.

Top Seneca Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Seneca?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Check out the lakeside setting in Seneca - worth a picture or two! Be sure to enjoy the coffeehouses during your stay. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Seneca?
Take in the sights and attractions that Seneca offers with a visit to Keowee Reservoir, Lake Keowee, and Keowee Key Golf Course. If you have extra time while you're in the area, you might want to see Lake Hartwell and Oconee County Library Seneca Branch.
What is a Seneca spa hotel?
Spa hotels in Seneca provide lodging and have an on-site spa offering services including couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

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