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Recommended hotels in Seneca
1. Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area2.5 star property
Seneca
9.2 out of 10, Wonderful, (765 reviews)
9.2/10
Wonderful
(765 reviews)
$119 nightly
The price is $131
$131 total
Dec 4 - Dec 5
Total with taxes and fees
2. Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson2.5 star property
Seneca
9.2 out of 10, Wonderful, (902 reviews)
9.2/10
Wonderful
(902 reviews)
$99 nightly
The price is $109
$109 total
Dec 12 - Dec 13
Total with taxes and fees
3. Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area3.0 star property
Seneca
9.2 out of 10, Wonderful, (292 reviews)
9.2/10
Wonderful
(292 reviews)
$120 nightly
The price is $132
$132 total
Nov 22 - Nov 23
Total with taxes and fees
4. Lakeside Lodge Clemson
Lakeside Lodge Clemson2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,005 reviews)
9.0/10
Wonderful
(1,005 reviews)
$123 nightly
The price is $135
$135 total
Nov 12 - Nov 13
Total with taxes and fees
5. Best Western Seneca-Clemson
Best Western Seneca-Clemson2.5 star property
Seneca
8.4 out of 10, Very good, (700 reviews)
8.4/10
Very good
(700 reviews)
$94 nightly
The price is $103
$103 total
Dec 1 - Dec 2
Total with taxes and fees
6. Quality Inn Seneca US-123
Quality Inn Seneca US-1232.5 star property
Seneca
8.0 out of 10, Very good, (770 reviews)
8.0/10
Very good
(770 reviews)
$86 nightly
The price is $94
$94 total
Dec 1 - Dec 2
Total with taxes and fees
7. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy2.0 star property
Seneca
9.8 out of 10, Exceptional, (120 reviews)
9.8/10
Exceptional
(120 reviews)
$139 nightly
The price is $153
$153 total
Nov 30 - Dec 1
Total with taxes and fees
8. Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area2.0 star property
Seneca
6.8 out of 10, (797 reviews)
6.8/10
(797 reviews)
$71 nightly
The price is $79
$79 total
Dec 1 - Dec 2
Total with taxes and fees
9. Private Room #3
Private Room #3Downtown
9.0 out of 10, Wonderful, (23 reviews)
9.0/10
Wonderful
(23 reviews)
$194 nightly
The price is $210
$210 total
Nov 12 - Nov 13
Total with taxes and fees
10. Boutique hotel in historic downtown Seneca. Room #5, two King beds.
Boutique hotel in historic downtown Seneca. Room #5, two King beds.Downtown
9.0 out of 10, Wonderful, (22 reviews)
9.0/10
Wonderful
(22 reviews)
$187 nightly
The price is $203
$203 total
Nov 16 - Nov 17
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Seneca Hotel Reviews
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
10/10 Excellent
This is a fantastic place to stay and get away. Good for quiet work or true relaxation. Internet was blazing fast too. Can I stay forever?
This is a fantastic place to stay and get away. Good for quiet work or true relaxation. Internet was blazing fast too. Can I stay forever?
Jonathan
The Inn at Patrick Square
The Inn at Patrick SquareClemson
10/10 Excellent
This was an absolutely beautiful and VERY clean hotel. It is not too far from Clemson University. We will stay here for all of our visits to Clemson.
This was an absolutely beautiful and VERY clean hotel. It is not too far from Clemson University. We will stay here for all of our visits to Clemson.
SHARRA
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown ClemsonClemson
10/10 Excellent
We had an amazing stay. From the beautifully decorated, relaxing room, to the restaurant decor and excellent service and food, to the cute coffee stations on each floor, to the bar and deck, it was all fantastic!
We had an amazing stay. From the beautifully decorated, relaxing room, to the restaurant decor and excellent service and food, to the cute coffee stations on each floor, to the bar and deck, it was all fantastic!
Amy
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson AreaSeneca
10/10 Excellent
I liked everything about this Hampton Inn. The staff were very professional in appearance and kindness. I needed more towels and it was late at night and they came right up with them. It was very quiet and the breakfast was such a great variety and taste was great. We will stay there again when we visit family. It was wonderful and price was good.
I liked everything about this Hampton Inn. The staff were very professional in appearance and kindness. I needed more towels and it was late at night and they came right up with them. It was very quiet and the breakfast was such a great variety and taste was great. We will stay there again when we visit family. It was wonderful and price was good.
LuAnn
Liberty Hall Bed and Breakfast
Liberty Hall Bed and BreakfastPendleton
10/10 Excellent
we were super excited to arrive to such a beautiful property!
Unsure why people stay in corporate hotels when this gem is available!
Our room was stellar! cozy, clean and quiet. The upstairs front porch was a delight to relax on, perfect for unwinding after our hike to a local waterfall
The hosts were very easy to interact with through text
we looking forward to the next time I can stay~
we were super excited to arrive to such a beautiful property!
Unsure why people stay in corporate hotels when this gem is available!
Our room was stellar! cozy, clean and quiet. The upstairs front porch was a delight to relax on, perfect for unwinding after our hike to a local waterfall
The hosts were very easy to interact with through text
we looking forward to the next time I can stay~
loretta
The Abernathy of Clemson
The Abernathy of ClemsonClemson
10/10 Excellent
Amazing hotel, amazing location. Highly recommended.
Amazing hotel, amazing location. Highly recommended.
Michele
Carolina Camp Cedar
Carolina Camp CedarPickens
10/10 Excellent
The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!
The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!
Katlynn
Clemson Memorabilia House
Clemson Memorabilia HouseClemson
10/10 Excellent
The space was super clean and well appointed and the hosts were so helpful. They let us check in really early so we wouldn’t be without a space with our toddler all day when we ended up arriving ahead of schedule!
The space was super clean and well appointed and the hosts were so helpful. They let us check in really early so we wouldn’t be without a space with our toddler all day when we ended up arriving ahead of schedule!
Marissa
Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
10/10 Excellent
It was very clean and quiet- well kept and a nice play to come “home” to after a long, emotional day of dropping daughter off at Clemson!!
It was very clean and quiet- well kept and a nice play to come “home” to after a long, emotional day of dropping daughter off at Clemson!!
Margot
Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
10/10 Excellent
Love this place. It's pristine, the staff is wonderful, rooms were large and the parking was so perfect!!!
Love this place. It's pristine, the staff is wonderful, rooms were large and the parking was so perfect!!!
Maria
The Bleckley Inn
The Bleckley InnAnderson
10/10 Excellent
Very nice property. Conveniently located in downtown.
Very nice property. Conveniently located in downtown.
Anonymous traveler
Residence Inn by Marriott Anderson Clemson
Residence Inn by Marriott Anderson ClemsonAnderson
10/10 Excellent
It was a great place to stay when going to a Clemson football game. The staff was great and the rooms were clean.
It was a great place to stay when going to a Clemson football game. The staff was great and the rooms were clean.
Tina
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
10/10 Excellent
Lovely hotel. Clean, comfy and everything is expect for the price.
Plus free breakfast!
Lovely hotel. Clean, comfy and everything is expect for the price.
Plus free breakfast!
Ruth
Courtyard Marriott Clemson
Courtyard Marriott ClemsonClemson
10/10 Excellent
Courtyard had a lot of upgraded amenties. Fresh, new, clean. Very comfortable and well kept.
Courtyard had a lot of upgraded amenties. Fresh, new, clean. Very comfortable and well kept.
Anonymous traveler
Home2 Suites by Hilton Anderson Downtown
Home2 Suites by Hilton Anderson DowntownAnderson
10/10 Excellent
Very nice hotel and staff.
Very nice hotel and staff.
scott
Hilton Garden Inn Anderson
Hilton Garden Inn AndersonAnderson
10/10 Excellent
Wonderful hotel.
Complimentary breakfast would put it over the top!
Wonderful hotel.
Complimentary breakfast would put it over the top!
THOMAS
Hampton Inn Hartwell
Hampton Inn HartwellHartwell
10/10 Excellent
Staff was very friendly. Room was nice & clean.
Staff was very friendly. Room was nice & clean.
Aerial T
Find out more about Seneca
Top Seneca attractions for a relaxing vacation
Seneca, South Carolina, offers an enticing blend of natural beauty and relaxation, making it a perfect spot for travelers seeking hotels with spas. Explore the stunning Lake Hartwell, where you can indulge in a leisurely afternoon of fishing or boating, followed by a soothing massage at a nearby spa. The picturesque Oconee State Park provides hiking trails that lead you through lush forests and serene waterfalls, ideal for a refreshing retreat after a day of wellness. For a unique experience, visit the South Carolina Botanical Garden, where you can stroll through beautifully curated landscapes and enjoy the tranquility of nature, setting the perfect mood for a day of pampering. Don’t miss out on the charming downtown area, filled with local boutiques and cafes that invite you to unwind. Consider staying in a hotel near the lakefront where you can enjoy stunning sunset views while planning your next spa treatment, ensuring a restful and rejuvenating getaway.
Frequently Asked Questions
Looking for a spa hotel in Seneca?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Check out the lakeside setting in Seneca - worth a picture or two! Be sure to enjoy the coffeehouses during your stay. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Seneca?
Take in the sights and attractions that Seneca offers with a visit to Lake Keowee, Keowee Key Golf Course, and Lake Hartwell. If you have extra time while you’re in the area, you might want to see Oconee County Library Seneca Branch and Keowee Reservoir.
What is a Seneca spa hotel?
Spa hotels in Seneca provide lodging and have an on-site spa offering services including couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.