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Find spa resorts & hotels in South Central Houston, Houston from $144

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Top South Central Houston Resorts & Hotels with Spas

Hotel Zaza Houston Museum District

4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (1840)
"Very nice room, great staff, excellent food & drink."
United States
Mary
$289 nightly
The price is $338
Dec 11 - Dec 12
Total with taxes and fees
Hotel Zaza Houston Museum District

Hilton Americas-Houston

4.0 star property
Downtown Houston
9.4 out of 10, Exceptional, (1595)
"Clean, great location and super convenient food options!"
United States
Valerie
$147 nightly
The price is $172
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hilton Americas-Houston

Blossom Hotel Houston, Curio Collection by Hilton

4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3590)
"Everything about our stay was excellent. "
United States
Clarence
$123 nightly
The price is $144
Dec 15 - Dec 16
Total with taxes and fees
Blossom Hotel Houston, Curio Collection by Hilton

Omni Houston Hotel

4.0 star property
Greater Uptown
9.0 out of 10, Wonderful, (1005)
"Great location! "
United States
Fletcher
$162 nightly
The price is $189
Dec 6 - Dec 7
Total with taxes and fees
Omni Houston Hotel

The Laura Hotel, Houston Downtown, Autograph Collection

4.5 star property
Downtown Houston
9.0 out of 10, Wonderful, (1036)
"I would stay at this hotel again "
United States
Domonique
$182 nightly
The price is $213
Dec 6 - Dec 7
Total with taxes and fees
The Laura Hotel, Houston Downtown, Autograph Collection

JW Marriott Houston Downtown

5.0 star property
Downtown Houston
9.0 out of 10, Wonderful, (1000)
"Love the room very kind personal at the check in. "
United States
Antonia
$198 nightly
The price is $231
Dec 19 - Dec 20
Total with taxes and fees
JW Marriott Houston Downtown

Marriott Marquis Houston

4.0 star property
Downtown Houston
9.0 out of 10, Wonderful, (1007)
"Completely loved our stay at this location. "
United States
Miriam
$211 nightly
The price is $246
Jan 1 - Jan 2, 2026
Total with taxes and fees
Marriott Marquis Houston

Hotel ZaZa Houston Memorial City

4.0 star property
Memorial
9.4 out of 10, Exceptional, (1003)
"Excellent service at spa ,front desk and restaurant "
United States
Kevin
$269 nightly
The price is $315
Dec 14 - Dec 15
Total with taxes and fees
Hotel ZaZa Houston Memorial City

Four Seasons Hotel Houston

5.0 star property
Downtown Houston
9.2 out of 10, Wonderful, (1002)
"Just beautiful. I recommend"
United States
LYDIA CHISOM
$439 nightly
The price is $514
Jan 1 - Jan 2, 2026
Total with taxes and fees
Four Seasons Hotel Houston

Thompson Houston, by Hyatt

4.0 star property
Fourth Ward
9.4 out of 10, Exceptional, (220)
"The rooms were very clean and well appointed."
United States
John
$279 nightly
The price is $326
Dec 14 - Dec 15
Total with taxes and fees
Thompson Houston, by Hyatt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about South Central Houston

Top South Central Houston attractions for a relaxing vacation

Travelers seeking a rejuvenating escape in South Central Houston will find a delightful blend of relaxation and adventure. Start your journey at the nearby Houston Museum District, where you can explore world-class museums like the Museum of Fine Arts and the Houston Museum of Natural Science, perfect for family visits and cultural enrichment. After a day of exploration, unwind at one of the local spas, such as the luxurious Trellis Spa at The Houstonian, known for its serene ambiance and signature treatments that incorporate local botanicals. Foodies will appreciate the vibrant culinary scene, with restaurants like Brennan's of Houston offering exquisite dining experiences that can be the perfect prelude to a spa day. For outdoor enthusiasts, the nearby Hermann Park invites you to stroll through its scenic gardens or take a paddleboat ride on the lake, providing a refreshing break before returning to your hotel. As the sun sets, retreat to your hotel, where you'll be greeted with attentive service and stunning amenities. Imagine relaxing in a plush robe while sipping herbal tea at a rooftop pool, soaking in the vibrant skyline—this is the essence of a spa hotel experience in South Central Houston.

Find the best hotels & resorts with spas in South Central Houston

For travelers seeking a rejuvenating escape in South Central Houston, these hotels offer exceptional spa services and amenities to pamper body and mind.

Hotel Zaza Houston Museum District

  • Why it's great for tailored spa getaway: Hotel Zaza Houston Museum District is the perfect retreat for spa enthusiasts, featuring a remarkable guest review rating of 9.0. This luxurious hotel offers a full-service spa that promises wellness experiences, including body treatments, hydrotherapy, aromatherapy, and a range of massages tailored to unwind and revitalize guests.
  • Other amenities: Guests can enjoy an outdoor pool and a terrace for relaxation, along with complimentary Frette Italian sheets and designer toiletries for added comfort. The hotel also provides 24-hour fitness facilities, valet parking, and daily housekeeping. Unique features such as couples dining, hydromassage showerheads, and champagne service elevate the experience, ensuring a memorable stay that blends relaxation with luxury.
  • Neighborhood: South Central Houston
  • Nearby attractions: Hermann Park - 0.21 miles, Houston Museum of Fine Arts - 0.26 miles, Houston Natural Science Museum - 0.33 miles

Top South Central Houston Hotel Reviews

Frequently asked questions

Looking for a spa hotel in South Central Houston?
Soothe the senses with some time in one of our wonderful spa hotels. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What's there to see and do in South Central Houston?
Experience South Central Houston with a stop at Midtown Arts and Theater Center Houston, Children's Museum of Houston, and Houston Natural Science Museum. If you have extra time while you're in the area, you might want to stop by Houston Museum of Fine Arts and Houston Zoo.
What is a South Central Houston spa hotel?
Spa hotels in South Central Houston provide lodging and have an on-site spa which offers services like therapies as well as body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.

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