Photo by Jessica Richter
Find all hotels by Independent in Southeast Missouri, MO from $51
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check Southeast Missouri hotel availability
Compare rooms and suites by Independent in Southeast Missouri with rates, reviews, and availability. Most hotels are fully refundable.
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
8.8 out of 10, Excellent, (1008)
The price is $66
$75 total
includes taxes & fees
Jun 17 - Jun 18
Travel Inn & Suites
Travel Inn & Suites
8.4 out of 10, Very Good, (523)
The price is $60
$69 total
includes taxes & fees
May 28 - May 29
The Farmstead Hotel
The Farmstead Hotel
9.0 out of 10, Wonderful, (193)
The price is $105
$119 total
includes taxes & fees
May 28 - May 29
Save an average of 15% on thousands of hotels when you're signed in
New Orleans Inn Portageville
New Orleans Inn Portageville
8.0 out of 10, Very Good, (428)
The price is $52
$57 total
includes taxes & fees
Jun 2 - Jun 3
Town House Inn
Town House Inn
8.0 out of 10, Very Good, (292)
The price is $51
$56 total
includes taxes & fees
Jun 2 - Jun 3
Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain View
8.6 out of 10, Excellent, (190)
The price is $100
$109 total
includes taxes & fees
Jun 3 - Jun 4
Dexter Inn
Dexter Inn
7.0 out of 10, Good, (239)
The price is $58
$66 total
includes taxes & fees
Jun 8 - Jun 9
Bullwinkles Rustic Lodge
Bullwinkles Rustic Lodge
8.8 out of 10, Excellent, (152)
The price is $84
$95 total
includes taxes & fees
May 31 - Jun 1
Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
6.0 out of 10, (139)
The price is $60
$68 total
includes taxes & fees
May 28 - May 29
Madison Inn Lodge
Madison Inn Lodge
7.4 out of 10, Good, (225)
The price is $86
$94 total
includes taxes & fees
May 29 - May 30
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Independent Southeast Missouri Hotel Guide
Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Southeast Missouri, Missouri. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Southeast Missouri hotels guarantees an unparalleled level of comfort and quality.
You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Southeast Missouri Independent locations may even offer extra little benefits and discounts for frequent travelers.
Recent reviews of Southeast Missouri hotelsExpedia verified reviews
5/5 Excellent
"Have stayed several times. Would stay again"
A verified traveler stayed at Auburn Place Hotel And Suites
Posted 2 days ago
Southeast Missouri Hotels by Brand
Hotels in Southeast Missouri Neighborhoods
Hotels near popular Southeast Missouri Attractions
- Hotels near Johnson's Shut-ins State Park
- Hotels near Elephant Rocks State Park
- Hotels near Mark Twain National Forest
- Hotels near Echo Bluff State Park
- Hotels near Current River
- Hotels near Ozark National Scenic Riverways
- Hotels near Southeast Missouri State University
- Hotels near Lake Wappapello
- Hotels near Big Spring
- Hotels near Alley Spring & Mill
More Hotel Options in Southeast Missouri
- Business Hotels (50)
- Casinos (13)
- Cheap Hotels (23)
- Family Hotels (60)
- Golf Hotels (28)
- Historic Hotels (10)
- Hotel Wedding Venues (16)
- Hotels & Resorts for Couples (17)
- Hotels with Air Conditioning (71)
- Hotels with Balconies (5)
- Hotels with Bars (19)
- Hotels with Connecting Rooms (24)
- Hotels with Free Breakfast (53)
- Hotels with Free Parking (65)
- Hotels with Free Wifi (64)
- Hotels with Hot Tubs (22)
- Hotels with Laundry Facilities (47)
- Hotels with Restaurants (67)
- Hotels with Suites (9)
- Hotels with Tennis Courts (5)
- Hotels with a Gym (35)
- Hotels with a Pool (45)
- Hotels with a View (5)
- Hotels with an Indoor Pool (26)
- Hotels with an Outdoor Pool (43)
- Hotels with smoking rooms (9)
- Luxury Hotels (12)
- Non-Smoking Hotels (33)
- Pet-friendly Hotels (48)
- Resorts & Hotels with Spas (14)
- Romantic Hotels (5)
- Winery Hotels (7)
More Accommodation Types in Southeast Missouri
- Condo Rentals (4,433)
- Vacation Homes (4,433)
- Apartments (2,201)
- Cabin Rentals (1,194)
- Cottages (665)
- Motels (217)
- Resorts (177)
- Lodges (134)
- Chalets (125)
- Villas (103)
- B&B (79)
- Farmstay (65)
- Guest Houses (59)
- RV Parks (44)
- Aparthotels (35)
- Inns (7)
- Condo Resorts (2)
- Hostels (2)
- Town Houses (2)
- Houseboats (1)
- Residences (1)
Explore more hotels
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Super 8 by Wyndham Farmington
- Pear Tree Inn Sikeston
- Silo Farm Haus- located in the heart of wine country!
- Comfort Inn Festus - St Louis South
- Quality Inn
- Candlewood Suites Cape Girardeau, an IHG Hotel
- Fairfield Inn & Suites by Marriott Poplar Bluff
- Courtyard by Marriott Cape Girardeau Downtown
- Best Western Plus Sikeston
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- The Farmstead Hotel
- Holiday Inn Express & Suites Perryville, an IHG Hotel
- Hampton Inn Poplar Bluff
- Super 8 by Wyndham Perryville
- Comfort Suites Jackson-Cape Girardeau
- Travel Inn & Suites
- New Orleans Inn Portageville
- Drury Inn & Suites Poplar Bluff
- Drury Inn & Suites Hayti Caruthersville
Expedia's Latest Trends
Hotels
Hotel Rooms in St. CharlesHotels in Country Club PlazaHotels in Power and Light DistrictSix Flags St. Louis hotelsHighway 76 Strip hotelsHotel Rooms in Southwest MissouriUniversity of Missouri hotelsHotel Rooms in Lee's SummitHotels in Downtown Kansas CityWorlds of Fun hotelsHotel Rooms in IndependenceHotel Rooms in ChesterfieldHotel Rooms in WentzvilleSouthwest Missouri Adults Only Resorts & HotelsHollywood Casino Amphitheatre hotelsSouthwest Missouri Hotels with a Swim-up BarArrowhead Stadium hotelsKauffman Stadium hotelsHotels in Downtown St. Louis
Cars
Activities
General