Title: The Best 5 Star Hotels in Fredericktown, MO  | Expedia.com

[Fredericktown Travel Guide](https://expedia.com/Fredericktown.dx55114)[Hotels in Fredericktown](https://expedia.com/Fredericktown-Hotels.d55114.Travel-Guide-Hotels)[Vacation Rentals in Fredericktown](https://expedia.com/Fredericktown-Vacation-Rentals.d55114.Travel-Guide-VacationRentals)[Flights to Fredericktown](https://expedia.com/Cheap-Flights-To-Fredericktown.d55114.Travel-Guide-Flights)[Car Rentals in Fredericktown](https://expedia.com/Car-Rentals-In-Fredericktown.d55114.Car-Rental-Guide)[Fredericktown Vacation Packages](https://expedia.com/Fredericktown.d55114.Destination-Travel-Guides)

![Castor River Shut-Ins Fredericktown Missouri Ozarks](https://images.trvl-media.com/place/55114/f689985b-15df-4aa2-b301-649b2fafd71b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/55114/f689985b-15df-4aa2-b301-649b2fafd71b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

## Check availability on Fredericktown 5 Star Hotels

Tonight

[Mar 3 - Mar 4](https://www.expedia.com/Hotel-Search?regionId=55114&startDate=2026-03-03&endDate=2026-03-04&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 4 - Mar 5](https://www.expedia.com/Hotel-Search?regionId=55114&startDate=2026-03-04&endDate=2026-03-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=55114&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=55114&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Fredericktown.

![Urban Lofts](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/1b66adae_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Urban Lofts

104 North Jackson Street Perryville MO

[Get rates](https://expedia.com/Hotel-Search?startDate=3%2F17%2F2026&endDate=3%2F18%2F2026&selected=39926011&PinnedHotelID=39926011&HadPinnedHotel=true&regionId=55114)

[](https://expedia.com/Perryville-Hotels-Urban-Lofts.h39926011.Hotel-Information)

Still don't see what you're looking for?

[See all properties in Fredericktown.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&regionId=55114&star=50)

You can also use these popular filters to refine your search.

[Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&regionId=55114&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&regionId=55114&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&regionId=55114&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&regionId=55114&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&regionId=55114&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Fredericktown

Stroll through the historic courthouse square where local shops serve homemade treats and the 1822 courthouse stands proudly. Outdoor enthusiasts can paddle the St. Francis River or hike nearby Mark Twain National Forest trails when summer temperatures cool in the evening.

[See all hotels in Fredericktown](https://www.expedia.com/Hotel-Search?startDate=2026-03-17&endDate=2026-03-18&adults=2&regionId=55114)

![Castor River Shut-Ins Fredericktown Missouri Ozarks](https://images.trvl-media.com/place/55114/f689985b-15df-4aa2-b301-649b2fafd71b.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high)

## Top Fredericktown Hotel Reviews

## Find out more about Fredericktown

You enjoy the finer things in life, both at home and on vacation. Indulge yourself on your impending break. There's no reason to delay a getaway to Fredericktown any longer. You'll join the multitudes of vacationers who have made Fredericktown so fashionable in the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve an outstanding getaway. Reserve one of our 5-star hotels in Fredericktown and indulge in the finer things in life for a while.

### Book the Best Fredericktown 5-Star Hotels

You'll have a fantastic time at one of these 5-star hotels. Top-notch customer care, luxurious bedding, and fabulous spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready to kick back and indulge. What creature comforts do you want in your lodging? A body scrub that will leave you feeling outstanding? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A rejuvenating facial treatment to help your cares fall away? Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs. 

You won't sleep and order room service the entire time, though. We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Fredericktown are the perfect place to relax after a busy day.

### Make Your Escape

The results are in, and Fredericktown 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Choose one of our Fredericktown 5-star hotels today and soothe yourself in luxe surroundings tomorrow.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in Fredericktown?

> - Search for the lowest price per night

### What makes a hotel 5 stars in Fredericktown?

### Are there any 5-star all-inclusive resorts in Fredericktown?

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