
Popular airlines from Clemson, SC (CEU-Oconee County Regional) to McGhee Tyson Airport (TYS)
- American Airlines
American Airlines
- United
United
- Southwest Airlines
Southwest Airlines
- Delta
Delta
- Frontier Airlines
Frontier Airlines
- JetBlue Airways
JetBlue Airways
- Alaska Airlines
Alaska Airlines
- Plan, book, fly with confidence
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Origin airport | Oconee County Regional |
Destination airport | McGhee Tyson |
Distance | 100 mi |
Clemson to Knoxville Flights
The cheapest times to fly from Clemson to Knoxville
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Clemson to Knoxville are during the month of . You can find some of the cheapest flights from Clemson to Knoxville with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Clemson to Knoxville
Sunday is one of the best days to book for cheap flights from Clemson to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Clemson to Knoxville
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Clemson to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Clemson to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Clemson to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
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Top Routes to Knoxville
- Chicago to Knoxville (ORD - TYS)
- Newark Liberty Intl. Airport to Knoxville (EWR - TYS)
- Chicago to Knoxville (MDW - TYS)
- San Diego to Knoxville (SAN - TYS)
- Los Angeles to Knoxville (LAX - TYS)
- Miami to Knoxville (MIA - TYS)
- Detroit to Knoxville (DTW - TYS)
- New York to Knoxville (LGA - TYS)
- Boston to Knoxville (BOS - TYS)
- Minneapolis to Knoxville (MSP - TYS)
- Denver to Knoxville (DEN - TYS)
- New York to Knoxville (JFK - TYS)
Top Routes to Knoxville
- American Airlines Chicago to Knoxville
- American Airlines Newark Liberty Intl. Airport to Knoxville
- Delta Chicago to Knoxville
- Delta Los Angeles to Knoxville
- American Airlines Miami to Knoxville
- Delta Detroit to Knoxville
- Delta Minneapolis to Knoxville
- American Airlines Denver to Knoxville
- American Airlines New York to Knoxville
- Delta Houston to Knoxville
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Greenville
Nearby Airports
- Greenville-Spartanburg Intl. Airport (GSP)
- Asheville Regional Airport (AVL)
- DeKalb-Peachtree Airport (PDK)
- McGhee Tyson Airport (TYS)
- Augusta Regional Airport (AGS)
- Fulton County Airport (FTY)
- Columbia Metropolitan Airport (CAE)
- Hartsfield-Jackson Atlanta Intl. Airport (ATL)
- Charlotte-Douglas Intl. Airport (CLT)
- Tri-Cities Regional Airport (TRI)
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