$491 Cheap Flights from Charleston (CHS) to Florence (FLO)

View $491 flight on Wed, Oct 8, 2025Opens in a new window

Popular airlines from Charleston Intl. Airport (CHS) to Florence, SC (FLO-Florence Regional)

Cheap Flights from Charleston to Florence (CHS-FLO)

Prices were available within the past 7 days and start at $491 for one-way flights and $658 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Oct 23 - Sun, Oct 26
CHS
Charleston
FLO
Florence
$658 Roundtrip, found 3 days ago
$658
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 23 from Charleston to Florence, returning Sun, Oct 26, priced at $658 found 3 days ago

Frequently asked questions

How much does a flight from Charleston Intl. Airport (CHS) to Florence Regional Airport (FLO) cost?
Get a cheap one-way flight from $491 or cheap return flight from $658 from Charleston Intl. Airport (CHS) to Florence Regional Airport (FLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Charleston Intl. Airport (CHS) to Florence Regional Airport (FLO)?
October is the cheapest month to fly from CHS to FLO. Traveling during an off-peak travel window is often the key to better flight prices.
What is the cheapest airline that flies from Charleston Intl. Airport (CHS) to Florence Regional Airport (FLO)?
To find the cheapest airline flying from CHS to FLO, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Charleston Intl. Airport (CHS) to Florence Regional Airport (FLO)?
There aren't any daily direct flights departing from Charleston Intl. Airport (CHS) to Florence Regional Airport (FLO). But you can book flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from CHS to FLO?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary depending on various factors, such as the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Charleston Intl. Airport (CHS) to Florence Regional Airport (FLO)?
To avoid potential delays on the Charleston Intl. Airport (CHS) to Florence Regional Airport (FLO) route, fly before 3 PM. Flights after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Charleston Intl. Airport (CHS) to Florence Regional Airport (FLO) last-minute?
Last-minute fares from CHS to FLO are typically more expensive. To lock in the best prices, start looking for flights well in advance. That being said, if your travel plans are flexible, you may score a cheap ticket right before you leave.
Is it cheaper to book a CHS to FLO flight and hotel package?
Opting for a CHS to FLO flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Pick from our wide range of hotels and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Charleston Intl. Airport (CHS) to Florence Regional Airport (FLO)?
If you booked your CHS to FLO flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more details.

Travel information

Travel information

Origin airport
Charleston Intl.
Destination airport
Florence Regional
Roundtrip price
$657
Distance
92 mi

Book with confidence

Book with confidence

Charleston to Florence Flights

The cheapest times to fly from Charleston to Florence

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charleston to Florence are during the month of October. You can find some of the cheapest flights from Charleston to Florence with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charleston to Florence

Sunday is one of the best days to book for cheap flights from Charleston to Florence: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charleston to Florence

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charleston to Florence in 2025. You can also book with separate airlines for your outbound and return journeys, from $491 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charleston to Florence flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charleston to Florence airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Charleston to Florence Flights

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*Available to One Key members.